Visual Impairment and Eye Diseases in HIV-infected People in the Antiretroviral Therapy (ART) Era in Rakai, Uganda

References

• Douek DC, Roederer M, Koup RA. Emerging concepts in the immunopathogenesis of AIDS. Annu Rev Med. 2009;60:471–484. doi:10.1146/annurev.med.60.041807.123549.
   PubMed Web of Science ®Google Scholar
• The Joint United Nations Programme on HIV/AIDS. Fact sheet 2018, Global Statistics - 2018 http://www.unaids.org/en/resources/fact-sheet. 2018.
   Google Scholar
• AVERT.org. HIV AND AIDS IN UGANDA 2018. Available from: https://www.avert.org/professionals/hiv-around-world/sub-saharan-africa/uganda#footnote55_owr6x36 
   Google Scholar
• Robinson MR, Ross ML, Whitcup SM. Ocular manifestations of HIV infection. Curr Opin Ophthalmol. 1999 Dec;10(6):431–437. doi:10.1097/00055735-199912000-00011.
   PubMedGoogle Scholar
• Bekele S, Gelaw Y, Tessema F. Ocular manifestation of HIV/AIDS and correlation with CD4+ cells count among adult HIV/AIDS patients in Jimma town, Ethiopia: a cross sectional study. BMC Ophthalmol. 2013 May;27(13):20. doi:10.1186/1471-2415-13-20.
   Google Scholar
• Chan CC, Zhang M. [Ocular manifestations in HIV/AIDS]. Zhonghua Yan Ke Za Zhi. Jun 2005;41(6):563–571.
   PubMedGoogle Scholar
• Cunningham ET Jr., Margolis TP. Ocular manifestations of HIV infection. N Engl J Med. 1998 Jul 23;339(4):236–244. doi:10.1056/NEJM199807233390406.
   PubMed Web of Science ®Google Scholar
• Salzberger B, Hartmann P, Hanses F, et al. Incidence and prognosis of CMV disease in HIV-infected patients before and after introduction of combination antiretroviral therapy. Infection. Oct 2005;33(5–6):345–349. doi:10.1007/s15010-005-5050-z.
   PubMed Web of Science ®Google Scholar
• Accorinti M, Pirraglia MP, Corradi R, et al. Changing patterns of ocular manifestations in HIV seropositive patients treated with HAART. Eur J Ophthalmol. Sep-Oct 2006;16(5):728–732. doi:10.1177/112067210601600511.
   PubMed Web of Science ®Google Scholar
• Otiti-Sengeri J, Meenken C, van den Horn GJ, et al. Ocular immune reconstitution inflammatory syndromes. Curr Opin HIV AIDS. 2008;3(4):432–437. doi:10.1097/COH.0b013e328302cc3d.
   PubMed Web of Science ®Google Scholar
• Wandeler G, Johnson LF, Egger M. Trends in life expectancy of HIV-positive adults on antiretroviral therapy across the globe: comparisons with general population. Curr Opin HIV AIDS. 2016 Sep;11(5):492–500. doi:10.1097/COH.0000000000000298.
   PubMed Web of Science ®Google Scholar
• Ballocca F, D’Ascenzo F, Gili S, et al. Cardiovascular disease in patients with HIV. Trends Cardiovasc Med. Nov 2017;27(8):558–563. doi:10.1016/j.tcm.2017.06.005.
   PubMed Web of Science ®Google Scholar
• Silverberg MJ, Chao C, Leyden WA, et al. HIV infection and the risk of cancers with and without a known infectious cause. AIDS. Nov 13 2009;23(17):2337–2345. doi:10.1097/QAD.0b013e3283319184.
   PubMed Web of Science ®Google Scholar
• Womack JA, Goulet JL, Gibert C, et al. Increased risk of fragility fractures among HIV infected compared to uninfected male veterans. PLoS One. Feb 16 2011;6(2):e17217. doi:10.1371/journal.pone.0017217.
   PubMed Web of Science ®Google Scholar
• Sulkowski MS, Thomas DL. Hepatitis C in the HIV-Infected Person. Ann Intern Med. 2003 Feb 4;138(3):197–207. doi:10.7326/0003-4819-138-3-200302040-00012.
   PubMed Web of Science ®Google Scholar
• Lucas GM, Mehta SH, Atta MG, et al. End-stage renal disease and chronic kidney disease in a cohort of African-American HIV-infected and at-risk HIV-seronegative participants followed between 1988 and 2004. AIDS. Nov 30 2007;21(18):2435–2443. doi:10.1097/QAD.0b013e32827038ad.
   PubMed Web of Science ®Google Scholar
• Saylor D, Dickens AM, Sacktor N, et al. HIV-associated neurocognitive disorder–pathogenesis and prospects for treatment. Nat Rev Neurol. Apr 2016;12(4):234–248. doi:10.1038/nrneurol.2016.27.
   PubMed Web of Science ®Google Scholar
• Jabs DA, Van Natta ML, Sezgin E, et al. Prevalence of intermediate-stage age-related macular degeneration in patients with acquired immunodeficiency syndrome. Am J Ophthalmol. Jun 2015;159(6):1115–1122 e1. doi:10.1016/j.ajo.2015.01.037.
   PubMed Web of Science ®Google Scholar
• Jabs DA, Van Natta ML, Pak JW, et al. Incidence of intermediate-stage age-related macular degeneration in patients with acquired immunodeficiency syndrome. Am J Ophthalmol. Jul 2017;179:151–158. doi:10.1016/j.ajo.2017.05.004.
   PubMed Web of Science ®Google Scholar
• Kempen JH, Sugar EA, Varma R, et al. Risk of cataract among subjects with acquired immune deficiency syndrome free of ocular opportunistic infections. Ophthalmology. Dec 2014;121(12):2317–2324. doi:10.1016/j.ophtha.2014.06.014.
   PubMed Web of Science ®Google Scholar
• Tamalet C, Tissot-Dupont H, Motte A, et al. Emergence of uncommon HIV-1 non-B subtypes and circulating recombinant forms and trends in transmission of antiretroviral drug resistance in patients with primary infection during the 2013-2015 period in Marseille, Southeastern France. J Med Virol. Oct 2018;90(10):1559–1567. doi:10.1002/jmv.25228.
   PubMed Web of Science ®Google Scholar
• Kong X, Kigozi G, Ssekasanvu J, et al. Association of medical male circumcision and antiretroviral therapy scale-up with community HIV incidence in Rakai, Uganda. JAMA. Jul 12 2016;316(2):182–190. doi:10.1001/jama.2016.7292.
   PubMed Web of Science ®Google Scholar
• Grabowski MK, Serwadda DM, Gray RH, et al. HIV prevention efforts and incidence of HIV in Uganda. N Engl J Med. Nov 30 2017;377(22):2154–2166. doi:10.1056/NEJMoa1702150.
   PubMed Web of Science ®Google Scholar
• Conroy SA, Laeyendecker O, Redd AD, et al. Changes in the distribution of HIV type 1 subtypes D and A in Rakai District, Uganda between 1994 and 2002. AIDS Res Hum Retroviruses. Oct 2010;26(10):1087–1091. doi:10.1089/aid.2010.0054.
   PubMed Web of Science ®Google Scholar
• Otiti-Sengeri J, Colebunders R, Reynolds SJ, et al. Elevated inflammatory cytokines in aqueous cytokine profile in HIV-1 infected patients with cataracts in Uganda. BMC Ophthalmol. Jan 19 2018;18(1):12. doi:10.1186/s12886-018-0680-y.
   PubMedGoogle Scholar
• World Health Organization. World Report on Vision. Switzerland; 2019.
   Google Scholar
• Deeks SG. HIV infection, inflammation, immunosenescence, and aging. Annu Rev Med. 2011;62:141–155. doi:10.1146/annurev-med-042909-093756.
   PubMed Web of Science ®Google Scholar
• Sacktor N, Saylor D, Nakigozi G, et al. Effect of HIV subtype and antiretroviral therapy on HIV-associated neurocognitive disorder (HAND) stage in Rakai, Uganda. J Acquir Immune Defic Syndr. Feb 15 2019;81:216–223. doi:10.1097/QAI.0000000000001992.
   PubMed Web of Science ®Google Scholar
• Kiwanuka N, Robb M, Laeyendecker O, et al. HIV-1 viral subtype differences in the rate of CD4+ T-cell decline among HIV seroincident antiretroviral naive persons in Rakai district, Uganda. J Acquir Immune Defic Syndr. Jun 2010;54(2):180–184. doi:10.1097/QAI.0b013e3181c98fc0.
   PubMed Web of Science ®Google Scholar
• Pathai S, Lawn SD, Weiss HA, et al. Increased ocular lens density in HIV-infected individuals with low nadir CD4 counts in South Africa: evidence of accelerated aging. J Acquir Immune Defic Syndr. Jul 1 2013;63(3):307–314. doi:10.1097/QAI.0b013e31828ad759.
   PubMed Web of Science ®Google Scholar
• Engstrom RE Jr., Holland GN, Hardy WD, et al. Hemorheologic abnormalities in patients with human immunodeficiency virus infection and ophthalmic microvasculopathy. Am J Ophthalmol. Feb 15 1990;109(2):153–161. doi:10.1016/S0002-9394(14)75980-X.
   PubMed Web of Science ®Google Scholar
• Schaftenaar E, Khosa NS, Baarsma GS, et al. HIV-infected individuals on long-term antiretroviral therapy are at higher risk for ocular disease. Epidemiol Infect. Sep 2017;145(12):2520–2529. doi:10.1017/S0950268817000978.
   PubMed Web of Science ®Google Scholar
• Zetterberg M, Celojevic D. Gender and cataract–the role of estrogen. Curr Eye Res. 2015 Feb;40(2):176–190. doi:10.3109/02713683.2014.898774.
   PubMed Web of Science ®Google Scholar
• De Francesco D, Wit FW, Burkle A, et al. Do people living with HIV experience greater age advancement than their HIV-negative counterparts? AIDS. Feb 1 2019;33(2):259–268. doi:10.1097/QAD.0000000000002063.
   PubMed Web of Science ®Google Scholar
• Rasmussen LD, Kessel L, Molander LD, et al. Risk of cataract surgery in HIV-infected individuals: a Danish nationwide population-based cohort study. Clin Infect Dis. Dec 2011;53(11):1156–1163. doi:10.1093/cid/cir675.
   PubMed Web of Science ®Google Scholar
• Morales M, Nabha L, Toussant B, et al. Risk factors for premature nuclear cataract formation in Human Immunodeficiency Virus (HIV) infected individuals receiving antiretroviral therapy. Curr Res HIV/AIDS. 2016;CRHA:108.
   Google Scholar
• Klein BE, Klein R, Linton KL. Prevalence of age-related lens opacities in a population. The beaver dam eye study. Ophthalmology. 1992 Apr;99(4):546–552. doi:10.1016/S0161-6420(92)31934-7.
   PubMed Web of Science ®Google Scholar
• Lundstrom M, Stenevi U, Thorburn W. Gender and cataract surgery in Sweden 1992-1997. A retrospective observational study based on the Swedish national cataract register. Acta Ophthalmol Scand. 1999 Apr;77(2):204–208. doi:10.1034/j.1600-0420.1999.770218.x.
   PubMedGoogle Scholar
• Mitchell P, Cumming RG, Attebo K, et al. Prevalence of cataract in Australia: the blue mountains eye study. Ophthalmology. Apr 1997;104(4):581–588. doi:10.1016/S0161-6420(97)30266-8.
   PubMed Web of Science ®Google Scholar
• Johnson GJ, Minassian DC, Weale R. The epidemiology of eye disease. Community Eye Health. 1999;12:10.
   Google Scholar
• Naidoo K, Kempen JH, Gichuhi S, et al. Prevalence and causes of vision loss in sub-Saharan Africa in 2015: magnitude, temporal trends and projections. Br J Ophthalmol. 2020 Mar 30. doi:10.1136/bjophthalmol-2019-315217.
   Web of Science ®Google Scholar