Analysis of key candidate genes and pathways of endometriosis pathophysiology by a genomics-bioinformatics approach

Reference

• Cramer DW, Missmer SA. The epidemiology of endometriosis. Ann N Y Acad Sci. 2002;955:11–22. discussion 34–36, 396–406.
   PubMed Web of Science ®Google Scholar
• Blumenkrantz MJ, Gallagher N, Bashore RA, et al. Retrograde menstruation in women undergoing chronic peritoneal dialysis. Obstet Gynecol. 1981;57:667–670.
   PubMed Web of Science ®Google Scholar
• Garcia-Velasco JA, Somigliana E. Management of endometriomas in women requiring IVF: to touch or not to touch. Hum Reprod. 2009;24:496–501.
   PubMed Web of Science ®Google Scholar
• Pazhohan A, Amidi F, Akbari-Asbagh F, et al. The Wnt/beta-catenin signaling in endometriosis, the expression of total and active forms of beta-catenin, total and inactive forms of glycogen synthase kinase-3beta, WNT7a and DICKKOPF-1. Eur J Obstet Gynecol Reprod Biol. 2018;220:1–5.
   PubMed Web of Science ®Google Scholar
• Diao R, Wei W, Zhao J, et al. CCL19/CCR7 contributes to the pathogenesis of endometriosis via PI3K/Akt pathway by regulating the proliferation and invasion of ESCs. Am J Reprod Immunol. 2017;78:e12744.
   Web of Science ®Google Scholar
• Taniguchi F, Uegaki T, Nakamura K, et al. Inhibition of IAP (inhibitor of apoptosis) proteins represses inflammatory status via nuclear factor-kappa B pathway in murine endometriosis lesions. Am J Reprod Immunol. 2018;79:e12780.
   Web of Science ®Google Scholar
• Meola J, Rosa e Silva JC, Dentillo DB, et al. Differentially expressed genes in eutopic and ectopic endometrium of women with endometriosis. Fertil Steril. 2010;93:1750–1773.
   PubMed Web of Science ®Google Scholar
• Li X, Zhang Y, Zhao L, et al. Whole-exome sequencing of endometriosis identifies frequent alterations in genes involved in cell adhesion and chromatin-remodeling complexes. Hum Mol Genet. 2014;23:6008–6021.
   PubMed Web of Science ®Google Scholar
• Borghese B, Mondon F, Noel JC, et al. Gene expression profile for ectopic versus eutopic endometrium provides new insights into endometriosis oncogenic potential. Mol Endocrinol. 2008;22:2557–2562.
   PubMedGoogle Scholar
• Crispi S, Piccolo MT, D'Avino A, et al. Transcriptional profiling of endometriosis tissues identifies genes related to organogenesis defects. J Cell Physiol. 2013;228:1927–1934.
   PubMed Web of Science ®Google Scholar
• Eyster KM, Klinkova O, Kennedy V, et al. Whole genome deoxyribonucleic acid microarray analysis of gene expression in ectopic versus eutopic endometrium. Fertil Steril. 2007;88:1505–1533.
   PubMed Web of Science ®Google Scholar
• Hull ML, Escareno CR, Godsland JM, et al. Endometrial–peritoneal interactions during endometriotic lesion establishment. Am J Pathol. 2008;173:700–715.
   PubMed Web of Science ®Google Scholar
• Franceschini A, Szklarczyk D, Frankild S, et al. STRING v9.1: protein–protein interaction networks, with increased coverage and integration. Nucleic Acids Res. 2013;41(Database issue):D808–15.
   PubMed Web of Science ®Google Scholar
• Shannon P, Markiel A, Ozier O, et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 2003;13:2498–2504.
   PubMed Web of Science ®Google Scholar
• Hsieh YY, Chang CC, Chen SY, et al. XRCC1 399 Arg-related genotype and allele, but not XRCC1 His107Arg, XRCC1 Trp194Arg, KCNQ2, AT1R, and hOGG1 polymorphisms, are associated with higher susceptibility of endometriosis. Gynecol Endocrinol. 2012;28:305–309.
   PubMed Web of Science ®Google Scholar
• Carbajo-Lozoya J, Lutz S, Feng Y, et al. Angiotensin II modulates VEGF-driven angiogenesis by opposing effects of type 1 and type 2 receptor stimulation in the microvascular endothelium. Cell Signal. 2012;24:1261–1269.
   PubMed Web of Science ®Google Scholar
• MacKenzie A. Endothelium-derived vasoactive agents, AT1 receptors and inflammation. Pharmacol Ther. 2011;131:187–203.
   PubMed Web of Science ®Google Scholar
• Cakmak B, Cavusoglu T, Ates U, et al. Regression of experimental endometriotic implants in a rat model with the angiotensin II receptor blocker losartan. J Obstet Gynaecol Res. 2015;41:601–607.
   PubMed Web of Science ®Google Scholar
• Capobianco G, Wenger JM, Marras V, et al. Immunohistochemical evaluation of epithelial antigen Ber-Ep4 and CD10: new markers for endometriosis? Eur J Gynaecol Oncol. 2013;34:254–256.
   PubMed Web of Science ®Google Scholar
• Casey ML, MacDonald PC. Transforming growth factor-beta inhibits progesterone-induced enkephalinase expression in human endometrial stromal cells. J Clin Endocrinol Metab. 1996;81:4022–4027.
   PubMed Web of Science ®Google Scholar
• Klemmt PA, Carver JG, Kennedy SH, et al. Stromal cells from endometriotic lesions and endometrium from women with endometriosis have reduced decidualization capacity. Fertil Steril. 2006;85:564–572.
   PubMed Web of Science ®Google Scholar
• Saito A, Iwase A, Nakamura T, et al. Involvement of mesosalpinx in endometrioma is a possible risk factor for decrease of ovarian reserve after cystectomy: a retrospective cohort study. Reprod Biol Endocrinol. 2016;14:72.
   PubMed Web of Science ®Google Scholar
• Iwase A, Kotani T, Goto M, et al. Possible involvement of CD10 in the development of endometriosis due to its inhibitory effects on CD44-dependent cell adhesion. Reprod Sci. 2014;21:82–88.
   PubMed Web of Science ®Google Scholar
• Pazhohan A, Amidi F, Akbari-Asbagh F, et al. Expression and shedding of CD44 in the endometrium of women with endometriosis and modulating effects of vitamin D: a randomized exploratory trial. J Steroid Biochem Mol Biol. 2018;178:150–158.
   PubMed Web of Science ®Google Scholar
• Zhang Q, Liu X, Guo SW. Progressive development of endometriosis and its hindrance by anti-platelet treatment in mice with induced endometriosis. Reprod Biomed Online. 2017;34:124–136.
   PubMed Web of Science ®Google Scholar
• Chen X, Kong X, Liu D, et al. In vitro differentiation of endometrial regenerative cells into smooth muscle cells: alpha potential approach for the management of pelvic organ prolapse. Int J Mol Med. 2016;38:95–104.
   PubMed Web of Science ®Google Scholar
• Schreinemacher MH, Backes WH, Slenter JM, et al. Towards endometriosis diagnosis by gadofosveset-trisodium enhanced magnetic resonance imaging. PLoS One. 2012;7:e33241.
   PubMed Web of Science ®Google Scholar
• Barcena de Arellano ML, Gericke J, Reichelt U, et al. Immunohistochemical characterization of endometriosis-associated smooth muscle cells in human peritoneal endometriotic lesions. Hum Reprod. 2011;26:2721–2730.
   PubMed Web of Science ®Google Scholar
• van Kaam KJ, Schouten JP, Nap AW, et al. Fibromuscular differentiation in deeply infiltrating endometriosis is a reaction of resident fibroblasts to the presence of ectopic endometrium. Hum Reprod. 2008;23:2692–2700.
   PubMed Web of Science ®Google Scholar
• Canosa S, Moggio A, Brossa A, et al. Angiogenic properties of endometrial mesenchymal stromal cells in endothelial co-culture: an in vitro model of endometriosis. Mol Hum Reprod. 2017;23:187–198.
   PubMed Web of Science ®Google Scholar
• Martin TA, Jiang WG. Loss of tight junction barrier function and its role in cancer metastasis. Biochim Biophys Acta. 2009;1788:872–891.
   PubMed Web of Science ®Google Scholar
• Okamoto M, Nasu K, Abe W, et al. Enhanced miR-210 expression promotes the pathogenesis of endometriosis through activation of signal transducer and activator of transcription 3. Hum Reprod. 2015;30:632–641.
   PubMed Web of Science ®Google Scholar
• Frank B, Hoeft B, Hoffmeister M, et al. Association of hydroxyprostaglandin dehydrogenase 15-(NAD) (HPGD) variants and colorectal cancer risk. Carcinogenesis. 2011;32:190–196.
   PubMed Web of Science ®Google Scholar
• Wu R, Zhou W, Chen S, et al. Lipoxin A4 suppresses the development of endometriosis in an ALX receptor-dependent manner via the p38 MAPK pathway. Br J Pharmacol. 2014;171:4927–4940.
   PubMed Web of Science ®Google Scholar
• Xu Z, Zhao F, Lin F, et al. Lipoxin A4 inhibits the development of endometriosis in mice: the role of anti-inflammation and anti-angiogenesis. Am J Reprod Immunol. 2012;67:491–497.
   PubMed Web of Science ®Google Scholar
• Sinreih M, Anko M, Kene NH, et al. Expression of AKR1B1, AKR1C3 and other genes of prostaglandin F2alpha biosynthesis and action in ovarian endometriosis tissue and in model cell lines. Chem Biol Interact. 2015;234:320–331.
   PubMed Web of Science ®Google Scholar
• Cobellis L, Razzi S, De Simone S, et al. The treatment with a COX-2 specific inhibitor is effective in the management of pain related to endometriosis. Eur J Obstet Gynecol Reprod Biol. 2004;116:100–102.
   PubMed Web of Science ®Google Scholar
• Alsalameh S, Burian M, Mahr G, et al. Review article: the pharmacological properties and clinical use of valdecoxib, a new cyclo-oxygenase-2-selective inhibitor. Aliment Pharmacol Ther. 2003;17:489–501.
   PubMed Web of Science ®Google Scholar
• Lousse JC, Defrere S, Colette S, et al. Expression of eicosanoid biosynthetic and catabolic enzymes in peritoneal endometriosis. Hum Reprod. 2010;25:734–741.
   PubMed Web of Science ®Google Scholar