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ASSISTED REPRODUCTIVE TECHNOLOGY

Cryopreservation of human embryos and oocytes for fertility preservation in cancer and non cancer patients: a mini review

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Pages 381-388 | Received 05 Sep 2019, Accepted 18 Jan 2020, Published online: 31 Jan 2020

References

  • Geyter D, Calhaz-Jorge C, Kupka MS, et al. European IVF-monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE). ART in Europe, 2014: results generated from European registries by ESHRE: The European IVF-monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE). Hum Reprod. 2018;33(9):1586–1601.
  • (a) Fidler MM, Gupta S, Soerjomataram I, et al. Cancer incidence and mortality among young adults aged 20–39 years worldwide in 2012: a population-based study. Lancet Oncol. 2017;18(12):1579–1589; (b) Fidler MM, Frobisher C, Hawkins MM, Nathan PC. Challenges and opportunities in the care of survivors of adolescent and young adult cancers. Pediatr Blood Cancer 2019;66(6):e27668.
  • Kim SY, Kim SK, Lee JR, et al. Toward precision medicine for preserving fertility in cancer patients: existing and emerging fertility preservation options for women. J Gynecol Oncol. 2016;27(2):e22.
  • Chung K, Donnez J, Ginsburg E, et al. Emergency IVF versus ovarian tissue cryopreservation: decision making in fertility preservation for female cancer patients. Fertil Steril. 2013;99(6):1534–1542.
  • Feigin E, Freud E, Fisch B, et al. Fertility preservation in female adolescents with malignancies. Ch 3. In: Moorland MT, editor. Cancer in female adolescents. Hauppauge (NY): Nova Science Publishers; 2008. p. 103–138.
  • Schover LR, van der Kaaij M, van Dorst E, et al. Sexual dysfunction and infertility as late effects of cancer treatment. EJC Suppl EJC Off J EORTC Eur Organ Res Treat Cancer Al. 2014;12(1):41–53.
  • Wallace WHB, Anderson RA, Irvine DS. Fertility preservation for young patients with cancer: who is at risk and what can be offered? Lancet Oncology. 2005;6(4):209–218.
  • Ethics Committee of the American Society for Reproductive Medicine. Fertility preservation and reproduction in patients facing gonadotoxic therapies: an Ethics Committee opinion. Fertil Steril. 2018:110(3):380–386.
  • Konc J, Kanyo K, Kriston R, et al. Cryopreservation of embryos and oocytes in human assisted reproduction. Biomed Res Int. 2014;2014:1–9.
  • Gellert SE, Pors SE, Kristensen SG, et al. Transplantation of frozen-thawed ovarian tissue: an update on worldwide activity published in peer-reviewed papers and on the Danish cohort. J Assist Reprod Genet. 2018;35(4):561–570.
  • Fleischer RT, Vollenhoven BJ, Weston GC. The effects of chemotherapy and radiotherapy on fertility in premenopausal women. Obstet Gynecol Surv. 2011;66(4):248–254.
  • Lee SJ, Schover LR, Partridge AH, et al. American Society of Clinical Oncology recommendations on fertility preservation in cancer patients. JCO. 2006;24(18):2917–2931.
  • Bar-Joseph H, Ben-Aharon I, Rizel S, et al. Doxorubicin-induced apoptosis in germinal vesicle (GV) oocytes. Reprod Toxicol. 2010;30(4):566–572.
  • Ezoe K, Murata N, Yabuuchi A, et al. Long-term adverse effects of cyclophosphamide on follicular growth and angiogenesis in mouse ovaries. Reprod Biol. 2014;14(3):238–242.
  • Meirow D, Biederman H, Anderson RA, et al. Toxicity of chemotherapy and radiation on female reproduction. Clin Obstet Gynecol. 2010;53(4):727–739.
  • Tarumi W, Suzuki N, Takahashi N, et al. Ovarian toxicity of paclitaxel and effect on fertility in the rat. J Obstet Gynaecol Res. 2009;35(3):414–420.
  • Yucebilgin MS, Terek MC, Ozsaran A, et al. Effect of chemotherapy on primordial follicular reserve of rat: an animal model of premature ovarian failure and infertility. Aust N Z J Obstet Gynaecol. 2004;44(1):6–9.
  • Abusief ME, Missmer SA, Ginsburg ES, et al. The effects of paclitaxel, dose density, and trastuzumab on treatment-related amenorrhea in premenopausal women with breast cancer. Cancer. 2010;116(4):791–798.
  • Bath LE, Wallace WH, Shaw MP, et al. Depletion of ovarian reserve in young women after treatment for cancer in childhood: detection by anti-Mullerian hormone, inhibin B and ovarian ultrasound. Hum Reprod. 2003;18(11):2368–2374.
  • Sklar CA, Mertens AC, Mitby P, et al. Premature menopause in survivors of childhood cancer: a report from the childhood cancer survivor study. J Natl Cancer Inst. 2006;98(13):890–896.
  • Baysal O, Bastings L, Beerendonk CC, et al. Decision-making in female fertility preservation is balancing the expected burden of fertility preservation treatment and the wish to conceive. Hum Reprod. 2015;30(7):1625–1634.
  • Schover LR, Brey K, Lichtin A, et al. Knowledge and experience regarding cancer, infertility, and sperm banking in younger male survivors. JCO. 2002;20(7):1880–1889.
  • Kim SS, Klemp J, Fabian C. Breast cancer and fertility preservation. Fertil Steril. 2011;95(5):1535–1543.
  • Lee S, Ozkavukcu S, Heytens E, et al. Value of early referral to fertility preservation in young women with breast cancer. JCO. 2010;28(31):4683–4686.
  • Lee S, Heytens E, Moy F, et al. Determinants of access to fertility preservation in women with breast cancer. Fertil Steril. 2011;95(6):1932–1936.
  • Kim SS, Oktay K, Gracia C, et al. Which patients pursue fertility preservation treatments? A multicenter analysis of the predictors of fertility preservation in women with breast cancer. Fertil Steril. 2012;97(3):671–676.
  • Chen C. Pregnancy after human oocyte cryopreservation. Lancet. 1986;1:884–886.
  • van Uem JF, Siebzehnrubl ER, Schuh B, et al. Birth after cryopreservation of unfertilized oocytes. Lancet Mar. 1987;28:752–753.
  • Oktay K, Cil AP, Bang H. Efficiency of oocyte cryopreservation: a meta-analysis. Fertil Steril. 2006;86(1):70–80.
  • Bernard A, Fuller BJ. Cryopreservation of human oocytes: current problems and perspectives. Hum Reprod. 1996;2:193–207.
  • Paynter SJ, Cooper A, Gregory L, et al. Permeability characteristics of human oocytes in the presence of the cryoprotectant dimethylsulphoxide. Hum Reprod. 1999;14(9):2338–2342.
  • Fuller BJ, Hunter JE, Bernard AG, et al. The Permeability of unfertilised oocytes to 1,2-propanediol: a comparison of mouse and human cells. Cryo Lett. 1992;13:287–292.
  • Hunter JE, Bernard A, Fuller BJ, et al. Plasma membrane water permeabilities of human oocytes: the temperature dependence of water movement in individual cells. J Cell Physiol. 1992;150(1):175–179.
  • Pickering SJ, Johnson MH. The influence of cooling on the organization of the meiotic spindle of the mouse oocyte. Hum Reprod. 1987;2(3):207–216.
  • Pickering SJ, Braude PR, Johnson MH, et al. Transient cooling to room-temperature can cause irreversible disruption of the meiotic spindle in the human oocyte. Fertil Steril. 1990;54(1):102–108.
  • Vincent C, Garnier V, Heyman Y, et al. Solvent effects on cytoskeletal organization and in-vivo survival after freezing of rabbit oocytes. J Reprod Fertil. 1989;87(2):809–820.
  • Vincent C, Pickering SJ, Johnson MH. The hardening effect of dimethylsulphoxide on the mouse zona pellucida requires the presence of an oocyte and is associated with a reduction in the number of cortical granules present. J Reprod Fertil. 1990;89(1):253–259.
  • Porcu E, Fabbri R, Seracchioli R, et al. Birth of a healthy female after intracytoplasmic sperm injection of cryopreserved human oocytes. Fertil Steril. 1997;68(4):724–726.
  • Benagiano G, Gianaroli L. The new Italian IVF legislation. Reprod Biomed Online. 2004;9(2):117–125.
  • Kuleshova L, Gianaroli L, Magli C, et al. Birth following vitrification of a small number of human oocytes: case report. Human Reproduction. 1999;14(12):3077–3079.
  • Kuwayama M, Vajta G, Kato O, et al. Highly efficient vitrification method for cryopreservation of human oocytes. Reprod Biomed Online. 2005;11(3):300–308.
  • Liebermann J, Tucker MJ. Comparison of vitrification and conventional cryopreservation of day 5 and day 6 blastocysts during clinical application. Fertil Steril. 2006;86(1):20–26.
  • Rienzi L, Gracia C, Maggiulli R, et al. Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance. Hum Reprod Update. 2017;23(2):139–155.
  • Li Z, Wang YA, Ledger W, et al. Clinical outcomes following cryopreservation of blastocysts by vitrification or slow freezing: a population-based cohort study. Hum Reprod. 2014;29(12):2794–2801.
  • Loutradi KE, Kolibianakis EM, Venetis CA, et al. Cryopreservation of human embryos by vitrification or slow freezing: a systematic review and meta-analysis. Fertil Steril. 2008;90(1):186–193.
  • Cobo A, Kuwayama M, Perez S, et al. Comparison of concomitant outcome achieved with fresh and cryopreserved donor oocytes vitrified by the Cryotop method. Fertil Steril. 2008;89(6):1657–1664.
  • Cobo A, Diaz C. Clinical application of oocyte vitrification: a systematic review and meta-analysis of randomized controlled trials. Fertil Steril. 2011;96(2):277–285.
  • Grifo JA, Noyes N. Delivery rate using cryopreserved oocytes is comparable to conventional in vitro fertilization using fresh oocytes: potential fertility preservation for female cancer patients. Fertil Steril. 2010;93(2):391–396.
  • Wise J. UK lifts ban on frozen eggs. BMJ. 2000;320(7231):334.
  • Practice Committees of American Society for Reproductive Medicine, Society for Assisted Reproductive Technology. Mature oocyte cryopreservation: a guideline. Fertil Steril (2013). 2012;99(1):37–43.
  • Cobo A, Meseguer M, Remoh J, et al. Use of cryo-banked oocytes in an ovum donation programme: a prospective, randomized, controlled, clinical trial. Hum Reprod. 2010;25(9):2239–2246.
  • Rienzi L, Romano S, Albricci L, et al. Embryo development of fresh ‘versus’ vitrified metaphase II oocytes after ICSI: a prospective randomized sibling-oocyte study. HumReprod. 2010;2 5:66–73.
  • Bielanski A, Nadin-Davis S, Sapp T, et al. Viral contamination of embryos cryopreserved in liquid nitrogen. Cryobiology. 2000;40(2):110–116.
  • Bielanski A. A review of the risk of contamination of semen and embryos during cryopreservation and measures to limit cross-contamination during banking to prevent disease transmission in ET practices. Theriogenology. 2012;77(3):467–482.
  • Chen Y, Zheng X, Yan J, et al. Neonatal outcomes after the transfer of vitrified blastocysts: closed versus open vitrification system. Reprod Biol Endocrinol. 2013;11(1):107.
  • Smith GD, Serafini PC, Fioravanti J, et al. Prospective randomized comparison of human oocyte cryopreservation with slow-rate freezing or vitrification. Fertil Steril. 2010;94(6):2088–2095.
  • Vanderzwalmen P, Zech NH, Ectors F, et al. Blastocyst transfer after aseptic vitrification of zygotes: an approach to overcome an impaired uterine environment. Reprod Biomed Online. 2012;25(6):591–599.
  • Sciorio R, Thong KJ, Pickering SJ. Single blastocyst transfer (SET) and pregnancy outcome of day 5 and day 6 human blastocysts vitrified using a closed device. Cryobiology. 2018;84:40–45.
  • Vanderzwalmen P, Zech NH, Prapas Y, et al. Closed carrier device: a reality to vitrify oocytes and embryos in aseptic conditions. Gynecol Obstet Fertil. 2010;38(9):541–546.
  • van Landuyt L, Stoop D, Verheyen G, et al. Van den Abbeel E. Outcome of closed blastocyst vitrification in relation to blastocyst quality: evaluation of 759 warming cycles in a single-embryo transfer policy. Hum Reprod. 2011;26(3):527–534.
  • Parmegiani L, Accorsi A, Cognigni GE, et al. Sterilization of liquid nitrogen with ultraviolet irradiation for safe vitrification of human oocytes or embryos. Fertil Steril. 2010;94(4):1525–1528.
  • Cobo A, Romero JL, Perez S, et al. Storage of human oocytes in the vapor phase of nitrogen. Fertil Steril. 2010;94(5):1903–1907.
  • Vajta G, Rienzi L, Ubaldi FM. Open versus closed systems for vitrification of human oocytes and embryos. Reprod Biomed Online. 2015;30(4):325–333.
  • Brison D, Cutting R, Clarke H, et al. ACE consensus meeting report: oocyte and embryo cryopreservation Sheffield 17.05.11. Hum Fertil. 2012;15(2):69–74.
  • Merlo DF, Ceppi M, Filiberti R, et al. Breast cancer incidence trends in European women aged 20–39 years at diagnosis. Breast Cancer Res Treat. 2012;134(1):363–370.
  • Cobo A, Garcia‐Velasco JA, Domingo J, et al. Elective and onco‐fertility preservation: factors related to IVF outcomes. Hum Reprod. 2018;33 (12):2222–2231.
  • Gilchrist RB, Lane M, Thompson JG. Oocyte-secreted factors: regulators of cumulus cell function and oocyte quality. Hum Reprod Update. 2008;14(2):159–177.
  • Mtango NR, Potireddy S, Latham K. Oocyte quality and maternal control of development. Int Rev Cell Mol Biol. 2008;268:223–290.
  • Haahr T, Esteves SC, Humaidan P. Individualized controlled ovarian stimulation in expected poor-responders: an update. Reprod Biol Endocrinol. 2018;16(1):20.
  • Best BP. Cryoprotectant toxicity: facts, issues, and questions. Rejuvenation Res. 2015;18(5):422–436.
  • Pegg DE. The history and principles of cryopreservation. Semin Reprod Med. 2002;20(1):005–013.
  • Meryman HT. Cryoprotective agents. Cryobiology. 1971;8(2):173–183.
  • Mazur P. Kinetics of water loss from cells at subzero temperatures and the likelihood of intracellular freezing. J Gen Physiol. 1963;47(2):347–369.
  • Lee JA, Sekhon L, Grunfeld L, et al. In-vitro maturation of germinal vesicle and metaphase I eggs prior to cryopreservation optimizes reproductive potential in patients undergoing fertility preservation. Curr Opin Obstet Gynecol. 2014;26(3):168–173.
  • Gualtieri R, Iaccarino M, Mollo V, et al. Slow cooling of human oocytes: ultrastructural injuries and apoptotic status. Fertil Steril. 2009;91(4):1023–1034.
  • Jones A, Van Blerkom J, Davis P, et al. Cryopreservation of metaphase II human oocytes effects mitochondrial membrane potential: implications for developmental competence. Hum Reprod. 2004;19(8):1861–1866.
  • Yan LY, Yan J, Qiao J, et al. Effects of oocyte vitrification on histone modifications. Reprod Fertil Dev. 2010;22(6):920–925.
  • Donnez J, Dolmans MM. Fertility preservation in women. Nat Rev Endocrinol. 2013;9(12):735–749.
  • Cakmak H, Katz A, Cedars MI, et al. Effective method for emergency fertility preservation: random-start controlled ovarian stimulation. Fertil Steril. 2013;100(6):1673–1680.
  • Reddy J, Oktay K. Ovarian stimulation and fertility preservation with the use of aromatase inhibitors in women with breast cancer. Fertil Steril. 2012;98(6):1363–1369.
  • Garcia-Velasco JA, Domingo J, Cobo A, et al. Five years’ experience using oocyte vitrification to preserve fertility for medical and non medical indications. Fertil Steril. 2013;99(7):1994–1999.
  • Martinez M, Rabadan S, Domingo J, et al. Obstetric outcome after oocyte vitrification and warming for fertility preservation in women with cancer. Reprod Biomed Online. 2014;29(6):722–728.
  • Chian RC, Huang YG, Tan SL, et al. Obstetric and perinatal outcome in 200 infants conceived from vitrified oocytes. Reprod Biomed Online. 2008;16(5):608–610.
  • Noyes N, Porcu E, Borini A. Over 900 cryopreservation babies born with no apparent increase in congenital anomalies. Reprod Biomed Online. 2009;18(6):769–776.
  • Trounson A, Mohr L. Human pregnancy following cryopreservation, thawing and transfer of an eight-cell embryo. Nature. 1983;305(5936):707–709.
  • Cohen J, Simons RF, Fehillity CB, et al. Birth after replacement of hatching blastocyst cryopreserved at expanded blastocyst stage. Lancet. 1985;16:647.
  • Dolmans MM, Hollanders de Ouderaen S, Demylle D, et al. Utilization rates and results of long-term embryo cryopreservation before gonadotoxic treatment. J Assist Reprod Genet. 2015;32(8):1233–1237.
  • Adashi EY, Barri PN, Berkowitz R, et al. Infertility therapy-associated multiple pregnancies (births): an ongoing epidemic. Reprod Biomed Online. 2003;7(5):515–542.
  • Cohen J, Wells D, Munne S. Removal of 2 cells from cleavage stage embryos is likely to reduce the efficacy of chromosomal tests that are used to enhance implantation rates. Fertil Steril. 2007;87(3):496–503.
  • Roque M, Lattes K, Serra S, et al. Fresh embryo transfer versus frozen embryo transfer in in vitro fertilization cycles: a systematic review and meta-analysis. Fertil Steril. 2013;99(1):156–162.
  • Jadoul P, Kim SS & on behalf of ISFP Practice Committee. Fertility consideration in young women with hematological malignancies. J Assist Reprod Genet. 2012;29(6):479–487.
  • Donnez J, Dolmans MM, Demylle D, et al. Livebirth after orthotopic transplantation of cryopreserved ovarian tissue. Lancet. 2004;364(9443):1405–1410.
  • Gosden RG, Baird DT, Wade JC, et al. Restoration of fertility to oophorectomized sheep by ovarian autografts stored at −196 °C. Human Reproduction. 1994;9(4):597–603.
  • Donnez J, Dolmans MM. Fertility preservation in women. N Engl J Med . 2017;377(17):1657–1665.
  • Masciangelo R, Hossay C, Donnez J, et al. Does the Akt pathway play a role in follicle activation after grafting of human ovarian tissue? Reprod BioMed Online. 2019;39(2):196–198.
  • Castrillon DH, Miao L, Kollipara R, et al. Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a. Science. 2003;301(5630):215–218.
  • Reddy P, Liu L, Adhikari D, et al. Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool. Science. 2008;319(5863):611–613.
  • Masciangelo R, Hossay C, Chiti MC, et al. Role of the PI3K and Hippo pathways in follicle activation after grafting of human ovarian tissue. J Assist Reprod Genet. 2019;15.

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