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Gynecological Endocrinology Volume 36, 2020 - Issue sup1: Reproductive medicine: cell technology and clinical practice
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Original Articles

Oxytocinergic regulation in pathogenesis of pelvic pain caused by adenomyosis 

Mekan Orazova FSAEI HE “Peoples’ Friendship University of Russia”, Moscow, RussiaCorrespondence[email protected]
View further author information
,
Victor Radzinskya FSAEI HE “Peoples’ Friendship University of Russia”, Moscow, RussiaView further author information
,
Olga Sharapovab City Clinical Hospital Named V. V. Vinogradov, Moscow, RussiaView further author information
,
Igor Kostina FSAEI HE “Peoples’ Friendship University of Russia”, Moscow, RussiaView further author information
&
Yurii Chitanavaa FSAEI HE “Peoples’ Friendship University of Russia”, Moscow, RussiaView further author information
Pages 20-23 | Received 08 Jul 2020, Accepted 25 Aug 2020, Published online: 11 Dec 2020

References

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  • Orazov MR, Radzinsky VE, Khamoshina MB, et al. Pathological neurogenesis is a key element in the pathogenesis of pelvic pain associated withadenomyosis. Pathol Physiol Experimental Ther. 2018;62(1):59–64.
  • Zhang X, Lu B, Huang X, et al. Innervation of endometrium and myometrium in women with painful adenomyosis and uterine fibroids. Fertil Steril. 2010;94(2):730–737.
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  • Radzinsky VE, Orazov MR, Nosenko EN. Expression of vascular endothelial growth factor (VEGF) in the uterus tissues as one of algogenesismechanisms in adenomyosis associated with chronic pelvic pain. Pathol Physiol Experimental Ther. 2016;60(1):32–35.
  • Jiang C, Cheng Z. Update of recent studies of adenomyosis-associated dysmenorrhea. Gynecol Minimally Invasive Ther. 2016;5(4):137–140.
  • Mechsner S, Grum B, Gericke C, et al. Possible roles of oxytocin receptor and vasopressin-1α receptor in the pathomechanism of dysperistalsis and dysmenorrhea in patients with adenomyosis uteri. Fertil Steril. 2010;94(7):2541–2546.
  • Guo SW, Mao X, Ma Q, et al. Dysmenorrhea and its severity are associated with increased uterine contractility and overexpression of oxytocin receptor (OTR) in women with symptomatic adenomyosis. Fertil Steril. 2013;99(1):231–240.
  • Zhang Y, Yu P, Sun F, et al. Expression of oxytocin receptors in the uterine junctional zone in women with adenomyosis. Acta Obstet Gynecol Scand. 2015;94(4):412–418.
  • Nie J, Liu X, Guo SW. Immunoreactivity of oxytocin receptor and transient receptor potential vanilloid type 1 and its correlation with dysmenorrhea in adenomyosis. Am J Obstet Gynecol. 2010;202(4):346.e1.
  • Li Y, Zou S, Xia X, et al. Human adenomyosis endometrium stromal cells secreting more nerve growth factor: impact and effect. Reprod Sci. 2015;22(9):1073–1082.

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