Diagnostic performance of the platelet function analyzer (PFA-100®) for the detection of disorders of primary haemostasis in patients with a bleeding history–a systematic review and meta-analysis

References

• Kratzer MA, Born GV. Simulation of primary haemostasis in vitro. Haemostasis 1985; 15: 357–362
   PubMedGoogle Scholar
• Kretschmer V, Schikor B, Söhngen D, Dietrich G. In vitro bleeding test-a simple method for the detection of aspirin effects on platelet function. Thromb Res 1989; 56: 593–602
   PubMed Web of Science ®Google Scholar
• Weippert-Kretschmer M, Witte M, Budde U, Vigh T, Kretschmer V, Scharrer I. The Thrombostat 4000. A sensitive screening test for von Willebrand's disease. Semin Thromb Hemost 1995; 21(Suppl. 2)44–51
   PubMed Web of Science ®Google Scholar
• Kundu S, Sio R, Mitu A, Ostgaard R. Evaluation of platelet function by PFA-100(TM). Clin Chem 1994; 40: 1827–1828
   Web of Science ®Google Scholar
• Harrison P. In vitro measurement of high-shear platelet adhesion and aggregation by the PFA-100. Methods Mol Biol 2004; 272: 215–223
   PubMedGoogle Scholar
• Francis JL. Platelet Function Analyzer (PFA)-100. Platelets, A Michelson. Academic Press, San Diego, CA 2002; 325–335
   Google Scholar
• Zupan IP, Sabovic M, Salobir B, Ponikvar JB, Cernelc P, Lavre J, Vujkovac B. The study of anaemia-related haemostasis impairment in haemodialysis patients by in vitro closure time test. Thromb Haemost 2005; 93: 375–379
   PubMed Web of Science ®Google Scholar
• Valeri CR, Cassidy G, Pivacek LE, Ragno G, Lieberthal W, Crowley JP, Khuri SF, Loscalzo J. Anemia-induced increase in the bleeding time: Implications for treatment of nonsurgical blood loss. Transfusion 2001; 41: 977–983
   PubMed Web of Science ®Google Scholar
• Mandal NG. PFA-100® and regional analgesia [letter]. Br J Anaesth 2004; 93: 468–469
   PubMed Web of Science ®Google Scholar
• Lijmer JG, Mol BW, Heisterkamp S, Bonsel GJ, Prins MH, van der Meulen JHP, Bossyut PMM. Empirical evidence of design-related bias in studies of diagnostic tests. JAMA 1999; 282: 1061–1066
   PubMed Web of Science ®Google Scholar
• Whiting P, Rutjes AWS, Reitsma JB, Bossuyt PMM, Kleijnen J. The development of QUADAS: A tool for the quality assessment of studies of diagnostic accuracy included in systematic reveiws. BMC Med Res Methodol 2003; 3: 25
   PubMedGoogle Scholar
• Reid MC, Lachs MS, Feinstein AR. Use of methodological standards in diagnostic test research. Getting better but still not good. JAMA 1995; 274: 645–651
   PubMed Web of Science ®Google Scholar
• Berlin JA. On behalf of University of Pennsylvania Meta-Analysis Blinding Study Group. Does blinding of readers affect the results of meta-analyses?. Lancet 2005; 350: 185–186
   Google Scholar
• Littenberg B, Moses LE. Estimating diagnostic accuracy from multiple conflicting reports: A new meta-analytic method. Med Decis Making 1993; 13: 313–321
   PubMed Web of Science ®Google Scholar
• Sterne JAC, Egger M, Davey Smith G. Investigating and dealing with publication and other biases. Systematic reviews in health care: Meta-analysis in context, M Egger, G Davey Smith, DG Altman. BMJ Publishing Group, London 2001; 189–208
   Google Scholar
• Deeks JJ. Systematic reviews of evaluations of diagnostic and screening tests. Systematic reviews in health care: Meta-analysis in context, M Egger, G Davey Smith, DG Altman. BMJ Publishing Group, London 2001; 248–282
   Google Scholar
• DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7: 177–188
   PubMed Web of Science ®Google Scholar
• Fleiss JL. The statistical basis of meta-analysis. Stat Methods Med Res 1993; 2: 121–145
   PubMedGoogle Scholar
• Moses LE, Shapiro D, Littenberg B. Combining independent studies of a diagnostic test into a summary ROC curve: Data-analytic approaches and some additional considerations. Stat Med 1993; 12: 1293–1316
   PubMed Web of Science ®Google Scholar
• van Houwelingen HC, Arends LR, Stijnen T. Advanced methods in meta-analysis: Multivariate approach and meta-regression. Stat Med 2002; 21: 589–624
   PubMed Web of Science ®Google Scholar
• Buyukasik Y, Karakus S, Goker H, Haznedaroglu IC, Ozatli D, Sayinalp N, Ozcebe OI, Dundar SV, Kirazli S. Rational use of the PFA-100 device for screening of platelet function disorders and von Willebrand disease. Blood Coagul Fibrinolysis 2002; 13: 349–353
   PubMed Web of Science ®Google Scholar
• Carcao MD, Blanchette VS, Dean JA, He L, Kern MA, Stain AM, Sparling CR, Stephens D, Ryan G, Freedman J, Rand ML. The Platelet Function Analyzer (PFA-100): A novel in vitro system for evaluation of primary haemostasis in children. Br J Haematol 1998; 101: 70–73
   PubMed Web of Science ®Google Scholar
• Carcao MD, Blanchette VS, Stephens D, He L, Wakefield CD, Butchard S, Christie DJ, Rand ML. Assessment of thrombocytopenic disorders using the Platelet Function Analyzer (PFA-100®). Br J Haematol 2002; 117: 961–964
   PubMed Web of Science ®Google Scholar
• Cariappa R, Wilhite TR, Parvin CA, Luchtman-Jones L. Comparison of PFA-100 and bleeding time testing in pediatric patients with suspected hemorrhagic problems. J Pediatr Hematol Oncol 2003; 25: 474–479
   PubMed Web of Science ®Google Scholar
• Cattaneo M, Lecchi A, Agati B, Lombardi R, Zighetti ML. Evaluation of platelet function with the PFA-100 system in patients with congenital defects of platelet secretion. Thromb Res 1999; 96: 213–217
   PubMed Web of Science ®Google Scholar
• Cattaneo M, Federici AB, Lecchi A, Agati B, Lombardi R, Stabile F, Bucciarelli P. Evaluation of the PFA-100 system in the diagnosis and therapeutic monitoring of patients with von Willebrand disease. Thromb Haemost 1999; 82: 35–39
   PubMed Web of Science ®Google Scholar
• Cesar JM, de Miguel D, Garcia AA, Burgaleta C. Platelet dysfunction in primary thrombocythemia using the platelet function analyzer, PFA-100. Am J Clin Pathol 2005; 123: 772–777
   PubMed Web of Science ®Google Scholar
• Dean JA, Blanchette VS, Carcao MD, Stain AM, Sparling CR, Siekmann J, Turecek PL, Lillicrap D, Rand ML. von Willebrand disease in a pediatric-based population − comparison of type 1 diagnostic criteria and use of the PFA-100 and a von Willebrand factor/collagen-binding assay. Thromb Haemost 2000; 84: 401–409
   PubMed Web of Science ®Google Scholar
• Escolar G, Cases A, Vinas M, Pino M, Calls J, Cirera I, Ordinas A. Evaluation of acquired platelet dysfunctions in uremic and cirrhotic patients using the platelet function analyzer (PFA-100): Influence of hematocrit elevation. Haematologica 1999; 84: 614–619
   PubMed Web of Science ®Google Scholar
• Favaloro EJ, Kershaw G, Bukuya M, Hertzberg M, Koutts J. Laboratory diagnosis of von Willebrand disorder (vWD) and monitoring of DDAVP therapy: Efficacy of the PFA-100 and vWF:CBA as combined diagnostic strategies. Haemophilia 2001; 7: 180–189
   PubMed Web of Science ®Google Scholar
• Favaloro EJ, Facey D, Henniker A. Use of a novel platelet function analyzer (PFA-100) with high sensitivity to disturbances in von Willebrand factor to screen for von Willebrand's disease and other disorders. Am J Hematol 1999; 62: 165–174
   PubMed Web of Science ®Google Scholar
• Favaloro EJ, Zafer M, Nair SC, Hertzberg M, North K. Evaluation of primary haemostasis in people with neurofibromatosis type 1. Clin Lab Haematol 2004; 26: 341–345
   PubMedGoogle Scholar
• Franchini M, Zugni C, Veneri D, Gandini G, Lippi G, Manzato F, Brazzarola P. High prevalence of acquired von Willebrand's syndrome in patients with thyroid diseases undergoing thyroid surgery. Haematologica 2004; 89: 1341–1346
   PubMed Web of Science ®Google Scholar
• Francis J, Francis D, Larson L, Helms E, Garcia M. Can the Platelet Function Analyzer (PFA(TM))-100 test substitute for the template bleeding time in routine clinical practice?. Platelets 1999; 10: 132–136
   PubMed Web of Science ®Google Scholar
• Francis JL. Platelet dysfunction detected at high shear in patients with heart valve disease. Platelets 2000; 11: 133–136
   PubMed Web of Science ®Google Scholar
• Fressinaud E, Veyradier A, Truchaud F, Martin I, Boyer-Neumann C, Trossaert M, Meyer D. Screening for von Willebrand disease with a new analyzer using high shear stress: A study of 60 cases. Blood 1998; 91: 1325–1331
   PubMed Web of Science ®Google Scholar
• Fressinaud E, Veyradier A, Sigaud M, Boyer-Neumann C, Le Boterff C, Meyer D. Therapeutic monitoring of von Willebrand disease: Interest and limits of a platelet function analyser at high shear rates. Br J Haematol 1999; 106: 777–783
   PubMed Web of Science ®Google Scholar
• Harrison C, Khair K, Baxter B, Russell-Eggitt I, Hann I, Liesner R. Hermansky-Pudlak syndrome: Infrequent bleeding and first report of Turkish and Pakistani kindreds. Arch Dis Child 2002; 86: 297–301
   PubMed Web of Science ®Google Scholar
• Harrison P, Robinson MS, Mackie IJ, Joseph J, McDonald SJ, Liesner R, Savidge GF, Pasi J, Machin SJ. Performance of the platelet function analyser PFA-100 in testing abnormalities of primary haemostasis. Blood Coagul Fibrinolysis 1999; 10: 25–31
   PubMed Web of Science ®Google Scholar
• Harrison P, Robinson M, Liesner R, Khair K, Cohen H, Mackie I, Machin S. The PFA-100: A potential rapid screening tool for the assessment of platelet dysfunction. Clin Lab Haematol 2002; 24: 225–232
   PubMedGoogle Scholar
• James AH, Lukes AS, Brancazio LR, Thames E, Ortel TL. Use of a new platelet function analyzer to detect von Willebrand disease in women with menorrhagia. Am J Obstet Gynecol 2004; 191: 449–455
   PubMed Web of Science ®Google Scholar
• Kerényi A, Schlammadinger A, Ajzner E, Szegedi I, Kiss C, Pap Z, Boda Z, Muszbek L. Comparison of PFA-100 closure time and template bleeding time of patients with inherited disorders causing defective platelet function. Thromb Res 1999; 96: 487–492
   PubMed Web of Science ®Google Scholar
• Koscielny J, Ziemer S, Radtke H, Schmutzler M, Pruss A, Sinha P, Salama A, Kiesewetter H, Latza R. A practical concept for preoperative identification of patients with impaired primary hemostasis. Clin Appl Thromb Hemost 2004; 10: 195–204
   PubMed Web of Science ®Google Scholar
• Kretschmer V, Weippert-Kretschmer M. Determination and treatment of disorders of primary haemostasis: Experience with routine application of the in vitro bleeding test. Hämostaseologie 1999; 19: 168–175
   Google Scholar
• Mammen EF, Alshameeri RS, Comp PC. Preliminary data from a field trial of the PFA-100 system. Semin Thromb Hemost 1995; 21(Suppl 2)113–121
   PubMed Web of Science ®Google Scholar
• Mammen EF, Comp PC, Gosselin R, Greenberg C, Hoots WK, Kessler CM, Larkin EC, Liles D, Nugent DJ. PFA-100 system: A new method for assessment of platelet dysfunction. Semin Thromb Hemost 1998; 24: 195–202
   PubMed Web of Science ®Google Scholar
• Ortel TL, James AH, Thames EH, Moore KD, Greenberg CS. Assessment of primary hemostasis by PFA-100 analysis in a tertiary care center. Thromb Haemost 2000; 84: 93–97
   PubMed Web of Science ®Google Scholar
• Philipp CS, Miller CH, Faiz A, Dilley A, Michaels LA, Ayers C, Bachmann G, Dowling N, Saidi P. Screening women with menorrhagia for underlying bleeding disorders: The utility of the platelet function analyser and bleeding time. Haemophilia 2005; 11: 497–503
   PubMed Web of Science ®Google Scholar
• Posan E, McBane RD, Grill DE, Motsko CL, Nichols WL. Comparison of PFA-100 testing and bleeding time for detecting platelet hypofunction and von Willebrand disease in clinical practice. Thromb Haemost 2003; 90: 483–490
   PubMed Web of Science ®Google Scholar
• Quiroga T, Goycoolea M, Munoz B, Morales M, Aranda E, Panes O, Pereira J, Mezzano D. Template bleeding time and PFA-100 have low sensitivity to screen patients with hereditary mucocutaneous hemorrhages: Comparative study in 148 patients. J Thromb Haemost 2004; 2: 892–898
   PubMed Web of Science ®Google Scholar
• Rand ML, Carcao MD, Blanchette VS. Use of the PFA-100 in the assessment of primary, platelet-related hemostasis in a pediatric setting. Semin Thromb Hemost 1998; 24: 523–529
   PubMed Web of Science ®Google Scholar
• Schlammadinger A, Kerényi A, Muszbek L, Boda Z. Comparison of the O'Brien filter test and the PFA-100 platelet analyzer in the laboratory diagnosis of von Willebrand's disease. Thromb Haemost 2000; 84: 88–92
   PubMed Web of Science ®Google Scholar
• Veyradier A, Fressinaud E, Boyer-Neumann C, Trossaert M, Meyer D. Von Willebrand factor ristocetin cofactor activity correlates with platelet function in a high shear stress system. Thromb Haemost 2000; 84: 727–728
   PubMed Web of Science ®Google Scholar
• Wuillemin WA, Gasser KM, Zeerleder SS, Lammle B. Evaluation of a Platelet Function Analyser (PFA-100) in patients with a bleeding tendency. Swiss Med Wkly 2002; 132: 443–448
   PubMed Web of Science ®Google Scholar
• Zupan IP, Sabovic M, Salobir B, Ponikvar JB, Cernelc P. Utility of in vitro closure time test for evaluating platelet-related primary hemostasis in dialysis patients. Am J Kidney Dis 2003; 42: 746–751
   PubMed Web of Science ®Google Scholar
• Haynes RB, Wilczynski NL. Optimal search strategies for retrieving scientifically strong studies of diagnosis from Medline: Analytical survey. BMJ 2004; 328: 1040, for the Hedges Team
   PubMed Web of Science ®Google Scholar
• Moher D, Pham B, Klassen TP, Schulz KF, Berlin JA, Jadad AR, Liberati A. What contributions do languages other than English make on the results of meta-analyses?. J Clin Epidemiol 2000; 53: 964–972
   PubMed Web of Science ®Google Scholar
• Egger M, Dickersin K, Davey Smith G. Problems and limitations in conducting systematic reviews. Systematic reviews in health care: Meta-analysis in context, M Egger, G Davey Smith, DG Altman. BMJ Publishing Group, London 2001; 43–68
   Google Scholar
• Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, Lijmer JG, Moher D, Rennie D, de Vet HCW. Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD initiative. BMJ 2003; 326: 41–44, for the STARD steering group
   PubMed Web of Science ®Google Scholar
• Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig LM, Moher D, Rennie D, de Vet HCW, Lijmer JG. The STARD statement for reporting studies of diagnostic accuracy: Explanation and elaboration. Clin Chem 2003; 49: 7–18
   PubMed Web of Science ®Google Scholar
• Harrison P. The role of PFA-100® testing in the investigation and management of haemostatic defects in children and adults. Br J Haematol 2005; 130: 3–10
   PubMed Web of Science ®Google Scholar
• Hayward CP, Harrison P, Cattaneo M, Ortel TL, Rao AK. Platelet function analyzer (PFA)-100 closure time in the evaluation of platelet disorders and platelet function. J Thromb Haemost 2006; 4: 312–319
   PubMed Web of Science ®Google Scholar
• Hunink MGM, Glasziou PP, Siegel JE, Weeks JC, Pliskin JS, Elstein AS, Weinstein MC. Decision making in health and medicine. Integrating evidence and values. Cambridge University Press, Cambridge 2001
   Google Scholar
• Rao AK. Congenital disorders of platelet secretion and signal transduction. Hemostasis and thrombosis. Basic principles and clinical practice, RW Colman, J Hirsh, VJ Marder, AW Clowes, GN George. Lippincott Williams & Wilkins, Philadelphia, PA 2001; 893–904
   Google Scholar
• Kleinbaum DG, Kupper LL, Muller KE, Nizam A. Applied regression analysis and other multivariable methods. Duxbury Press, Pacific Grove, CA 1998; 389–390
   Google Scholar