Association of platelet activation markers with recurrence of atrial fibrillation after pulmonary vein isolation

References

• Heppell RM, Berkin KE, McLenachan JM, Davies JA. Haemostatic and haemodynamic abnormalities associated with left atrial thrombosis in non-rheumatic atrial fibrillation. Heart 1997;77:407–411.
   PubMed Web of Science ®Google Scholar
• Hu YF, Chen YJ, Lin YJ, Chen SA. Inflammation and the pathogenesis of atrial fibrillation. Nat Rev Cardiol 2015;12(4):230–243.
   PubMed Web of Science ®Google Scholar
• Cai H, Li Z, Goette A, Mera F, Honeycutt C, Feterik K, Wilcox JN, Dudley SC, Jr., Harrison DG, Langberg JJ. Downregulation of endocardial nitric oxide synthase expression and nitric oxide production in atrial fibrillation: Potential mechanisms for atrial thrombosis and stroke. Circulation 2002;106:2854–2858.
   PubMed Web of Science ®Google Scholar
• Nakamura Y, Nakamura K, Fukushima-Kusano K, Ohta K, Matsubara H, Hamuro T, Yutani C, Ohe T. Tissue factor expression in atrial endothelia associated with nonvalvular atrial fibrillation: Possible involvement in intracardiac thrombogenesis. Thromb Res 2003;111:137–142.
   PubMed Web of Science ®Google Scholar
• Alonso A, Tang W, Agarwal SK, Soliman EZ, Chamberlain AM, Folsom AR. Hemostatic markers are associated with the risk and prognosis of atrial fibrillation: Tthe ARIC study. Int J Cardiol 2012;155:217–222.
   PubMed Web of Science ®Google Scholar
• Drabik L, Wolkow P, Undas A. Denser plasma clot formation and impaired fibrinolysis in paroxysmal and persistent atrial fibrillation while on sinus rhythm: Association with thrombin generation, endothelial injury and platelet activation. Thromb Res 2015;136:408–414.
   PubMed Web of Science ®Google Scholar
• Lip GY, Patel JV, Hughes E, Hart RG. High-sensitivity C-reactive protein and soluble CD40 ligand as indices of inflammation and platelet activation in 880 patients with nonvalvular atrial fibrillation: Relationship to stroke risk factors, stroke risk stratification schema, and prognosis. Stroke 2007;38:1229–1237.
   PubMed Web of Science ®Google Scholar
• Karasoy D, Gislason GH, Hansen J, Johannessen A, Kober L, Hvidtfeldt M, Ozcan C, Torp-Pedersen C, Hansen ML. Oral anticoagulation therapy after radiofrequency ablation of atrial fibrillation and the risk of thromboembolism and serious bleeding: Long-term follow-up in nationwide cohort of Denmark. Eur Heart J 2015;36:307–14a.
   PubMed Web of Science ®Google Scholar
• Lip GY, Lip PL, Zarifis J, Watson RD, Bareford D, Lowe GD, Beevers DG. Fibrin D-dimer and beta-thromboglobulin as markers of thrombogenesis and platelet activation in atrial fibrillation. Effects of introducing ultra-low-dose warfarin and aspirin. Circulation 1996;94:425–431.
   PubMed Web of Science ®Google Scholar
• Atalar E, Haznedaroglu IC, Acil T, Ozer N, Kilic H, Ovunc K, Aksoyek S, Nazli N, Kes S, Kabakci G, et al. Patients with paroxysmal atrial fibrillation but not paroxysmal supraventricular tachycardia display evidence of platelet activation during arrhythmia. Platelets 2003;14:407–411.
   PubMed Web of Science ®Google Scholar
• Erdem K, Ayhan S, Ozturk S, Bugra O, Bozoglan O, Dursin H, Yazici M, Daglar B. Usefulness of the mean platelet volume for predicting new-onset atrial fibrillation after isolated coronary artery bypass grafting. Platelets 2014;25:23–26.
   PubMed Web of Science ®Google Scholar
• Choudhury A, Chung I, Blann AD, Lip GY. Platelet surface CD62P and CD63, mean platelet volume, and soluble/platelet P-selectin as indexes of platelet function in atrial fibrillation: A comparison of “healthy control subjects” and “disease control subjects” in sinus rhythm. J Am Coll Cardiol 2007;49:1957–1964.
   PubMed Web of Science ®Google Scholar
• Blann AD, Choudhury A, Freestone B, Patel J, Lip GY. Soluble CD40 ligand and atrial fibrillation: Relationship to platelet activation, and endothelial damage/dysfunction. Int J Cardiol 2008;127:135–137.
   PubMed Web of Science ®Google Scholar
• Azzam H, Abousamra NK, Wafa AA, Hafez MM, El-Gilany AH. Upregulation of CD40/CD40L system in rheumatic mitral stenosis with or without atrial fibrillation. Platelets 2013;24:516–520.
   PubMed Web of Science ®Google Scholar
• Choudhury A, Chung I, Panja N, Patel J, Lip GY. Soluble CD40 ligand, platelet surface CD40 ligand, and total platelet CD40 ligand in atrial fibrillation: Relationship to soluble P-selectin, stroke risk factors, and risk factor intervention. Chest 2008;134:574–581.
   PubMed Web of Science ®Google Scholar
• Lim HS, Schultz C, Dang J, Alasady M, Lau DH, Brooks AG, Wong CX, Roberts-Thomson KC, Young GD, Worthley MI, et al. Time course of inflammation, myocardial injury, and prothrombotic response after radiofrequency catheter ablation for atrial fibrillation. Circ Arrhythm Electrophysiol 2014;7:83–89.
   PubMed Web of Science ®Google Scholar
• Elgueta R, Benson MJ, de Vries VC, Wasiuk A, Guo Y, Noelle RJ. Molecular mechanism and function of CD40/CD40L engagement in the immune system. Immunol Rev 2009;229:152–172.
   PubMed Web of Science ®Google Scholar
• Heeschen C, Dimmeler S, Hamm CW, van den Brand MJ, Boersma E, Zeiher AM, Simoons ML. Soluble CD40 ligand in acute coronary syndromes. N Engl J Med. 2003;348:1104–1111.
   PubMed Web of Science ®Google Scholar
• Anand SX, Viles-Gonzalez JF, Badimon JJ, Cavusoglu E, Marmur JD. Membrane-associated CD40L and sCD40L in atherothrombotic disease. Thromb Haemost 2003;90:377–384.
   PubMed Web of Science ®Google Scholar
• Aloui C, Prigent A, Sut C, Tariket S, Hamzeh-Cognasse H, Pozzetto B, Richard Y, Cognasse F, Laradi S, and Garraud O. The signaling role of CD40 ligand in platelet biology and in platelet component transfusion. Int J Mol Sci 2014;15:22342–22364.
   PubMed Web of Science ®Google Scholar
• Burdess A, Michelsen AE, Brosstad F, Fox KA, Newby DE, Nimmo AF. Platelet activation in patients with peripheral vascular disease: Reproducibility and comparability of platelet markers. Thromb Res 2012;129:50–55.
   PubMed Web of Science ®Google Scholar
• Michelson AD, Barnard MR, Krueger LA, Valeri CR, Furman MI. Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: Studies in baboons, human coronary intervention, and human acute myocardial infarction. Circulation 2001;104:1533–1537.
   PubMed Web of Science ®Google Scholar
• Wrigley BJ, Shantsila E, Tapp LD, Lip GY. Increased formation of monocyte-platelet aggregates in ischemic heart failure. Circ Heart Fail 2013;6:127–135.
   PubMed Web of Science ®Google Scholar
• Lukasik M, Dworacki G, Kufel-Grabowska J, Watala C, Kozubski W. Upregulation of CD40 ligand and enhanced monocyte-platelet aggregate formation are associated with worse clinical outcome after ischaemic stroke. Thromb Haemost 2012;107:346–355.
   PubMed Web of Science ®Google Scholar
• Pfluecke C, Berndt K, Wydra S, Tarnowski D, Barthel P, Quick S, Ulbrich S, Christoph M, Waessnig N, Speiser U, et al. Atrial fibrillation is associated with high levels of monocyte-platelet-aggregates and increased CD11b expression in patients with aortic stenosis. Thromb Haemost 2016;115(5):993–1000.
   Google Scholar
• Pfluecke C, Tarnowski D, Plichta L, Berndt K, Schumacher P, Ulbrich S, Forkmann M, Christoph M, Poitz DM, Wunderlich C, et al. Monocyte-platelet aggregates and CD11b expression as markers for thrombogenicity in atrial fibrillation. Clin Res Cardiol 2015(4):314–322.
   PubMed Web of Science ®Google Scholar
• Morgan E, Varro R, Sepulveda H, Ember JA, Apgar J, Wilson J, Lowe L, Chen R, Shivraj L, Agadir A, et al. Cytometric bead array: A multiplexed assay platform with applications in various areas of biology. Clin Immunol 2004;110:252–266.
   PubMed Web of Science ®Google Scholar
• Hayashi M, Takeshita K, Inden Y, Ishii H, Cheng XW, Yamamoto K, Murohara T. Platelet activation and induction of tissue factor in acute and chronic atrial fibrillation: Involvement of mononuclear cell-platelet interaction. Thromb Res 2011;128:e113–e118.
   PubMed Web of Science ®Google Scholar
• Kopjar T, Petricevic M, Gasparovic H, Svetina L, Milicic D, Biocina B. Postoperative atrial fibrillation is associated with high on-aspirin platelet reactivity. Ann Thorac Surg 2015;100:1704–1711.
   PubMed Web of Science ®Google Scholar
• Makowski M, Smorag I, Bissinger A, Grycewicz T, Masiarek K, Makowska J, Grabowicz W, Lubinski A, Baj Z. Effect of sinus rhythm restoration on platelet function in patients with lone atrial fibrillation. Int J Cardiol 2014;172:e22–e23.
   PubMed Web of Science ®Google Scholar
• Lim HS, Willoughby SR, Schultz C, Chakrabarty A, Alasady M, Lau DH, Roberts-Thomson KC, Worthley MI, Young GD, Sanders P. Successful catheter ablation decreases platelet activation and improves endothelial function in patients with atrial fibrillation. Heart Rhythm 2014;11:1912–1918.
   PubMed Web of Science ®Google Scholar
• Mahe I, Drouet L, Chassany O, Mazoyer E, Simoneau G, Knellwolf AL, Caulin C, Bergmann JF. D-dimer: a characteristic of the coagulation state of each patient with chronic atrial fibrillation. Thromb Res 2002;107:1–6.
   PubMed Web of Science ®Google Scholar
• Morris AE, Remmele RL, Jr., Klinke R, Macduff BM, Fanslow WC, Armitage RJ. Incorporation of an isoleucine zipper motif enhances the biological activity of soluble CD40L (CD154). J Biol Chem 1999;274:418–423.
   PubMed Web of Science ®Google Scholar
• Andre P, Nannizzi-Alaimo L, Prasad SK, Phillips DR. Platelet-derived CD40L: The switch-hitting player of cardiovascular disease. Circulation 2002;106:896–899.
   PubMed Web of Science ®Google Scholar
• Schonbeck U, Libby P. The CD40/CD154 receptor/ligand dyad. Cell Mol Life Sci 2001;58:4–43.
   PubMed Web of Science ®Google Scholar
• Conway DS, Buggins P, Hughes E, Lip GY. Relationship of interleukin-6 and C-reactive protein to the prothrombotic state in chronic atrial fibrillation. J Am Coll Cardiol 2004;43:2075–2082.
   PubMed Web of Science ®Google Scholar
• Badr ER, Gremmel T, Schneller A, Stegfellner M, Kaider A, Mannhalter C, Lang I, Panzer S. High levels of platelet-monocyte aggregates after valve replacement for aortic stenosis: Relation to soluble P-selectin and P-selectin glycoprotein ligand-1 genes. Thromb Res 2012;129:453–458.
   PubMed Web of Science ®Google Scholar
• Gremmel T, Ay C, Riedl J, Eichelberger B, Koppensteiner R, Panzer S. Platelet-specific markers are associated with monocyte-platelet aggregate formation and thrombin generation potential in advanced atherosclerosis. Thromb Haemost 2015;115(3):615–621.
   Google Scholar
• Choudhury A, Chung I, Blann AD, Lip GY. Elevated platelet microparticle levels in nonvalvular atrial fibrillation: Relationship to p-selectin and antithrombotic therapy. Chest 2007;131:809–815.
   PubMed Web of Science ®Google Scholar
• Watson T, Shantsila E, Lip GY. Mechanisms of thrombogenesis in atrial fibrillation: Virchow’s triad revisited. Lancet 2009;373:155–166.
   PubMed Web of Science ®Google Scholar
• Smyth SS, Monroe DM, III, Wysokinski WE, McBane RD, Whiteheart SW, Becker RC, Steinhubl SR. Platelet activation and its patient-specific consequences. Thromb Res 2008;122:435–441.
   PubMed Web of Science ®Google Scholar
• Shantsila E, Lip GY. The role of monocytes in thrombotic disorders. Insights from tissue factor, monocyte-platelet aggregates and novel mechanisms. Thromb Haemost. 2009;102:916–924.
   Google Scholar
• Kopp CW, Gremmel T, Steiner S, Seidinger D, Minar E, Maurer G, Huber K. Platelet-monocyte cross talk and tissue factor expression in stable angina vs. unstable angina/non ST-elevation myocardial infarction. Platelets 2011;22:530–536.
   Google Scholar
• Singh MV, Davidson DC, Kiebala M, Maggirwar SB. Detection of circulating platelet-monocyte complexes in persons infected with human immunodeficiency virus type-1. J Virol Methods 2012;181:170–176.
   PubMed Web of Science ®Google Scholar
• Lip GY, Frison L, Halperin JL, Lane DA. Identifying patients at high risk for stroke despite anticoagulation: A comparison of contemporary stroke risk stratification schemes in an anticoagulated atrial fibrillation cohort. Stroke 2010;41:2731–2738.
   PubMed Web of Science ®Google Scholar
• Evangelista V, Manarini S, Sideri R, Rotondo S, Martelli N, Piccoli A, Totani L, Piccardoni P, Vestweber D, de GG, Cerletti C. Platelet/polymorphonuclear leukocyte interaction: P-selectin triggers protein-tyrosine phosphorylation-dependent CD11b/CD18 adhesion: Role of PSGL-1 as a signaling molecule. Blood 1999;93:876–885.
   PubMed Web of Science ®Google Scholar
• Weyrich AS, McIntyre TM, McEver RP, Prescott SM, Zimmerman GA. Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-alpha secretion. Signal integration and NF-kappa B translocation. J Clin Invest 1995;95:2297–2303.
   PubMed Web of Science ®Google Scholar
• Wu Q, Ren J, Hu D, Wu X, Li G, Wang G, Gu G, Chen J, Li R, Li Y, et al. Monocyte subsets and monocyte-platelet aggregates: implications in predicting septic mortality among surgical critical illness patients. Biomarkers 2016;21(6):509–516.
   Web of Science ®Google Scholar
• Dopheide JF, Rubrech J, Trumpp A, Geissler P, Zeller GC, Bock K, Dunschede F, Trinh TT, Dorweiler B, Munzel T, et al. Leukocyte-platelet aggregates: A phenotypic characterization of different stages of peripheral arterial disease. Platelets 2016; [epub ahead of print].
   Google Scholar
• Sarma J, Laan CA, Alam S, Jha A, Fox KA, Dransfield I. Increased platelet binding to circulating monocytes in acute coronary syndromes. Circulation 2002;105:2166–2171.
   PubMed Web of Science ®Google Scholar
• Passacquale G, Vamadevan P, Pereira L, Hamid C, Corrigall V, Ferro A. Monocyte-platelet interaction induces a pro-inflammatory phenotype in circulating monocytes. PLoS One 2011;6:e25595.
   PubMed Web of Science ®Google Scholar
• Suzuki A, Fukuzawa K, Yamashita T, Yoshida A, Sasaki N, Emoto T, Takei A, Fujiwara R, Nakanishi T, Yamashita S, et al. Circulating intermediate CD14++CD16+monocytes are increased in patients with atrial fibrillation and reflect the functional remodelling of the left atrium. Europace 2016 doi:10.1093/europace/euv422
   Web of Science ®Google Scholar
• Christersson C, Johnell M, Siegbahn A. The influence of direct thrombin inhibitors on the formation of platelet-leukocyte aggregates and tissue factor expression. Thromb Res 2010;126:e327–e333.
   PubMed Web of Science ®Google Scholar