Comparison of diverse platelet activation markers as indicators for left atrial thrombus in atrial fibrillation

References

• Klein AL, Grimm RA, Murray RD, Apperson-Hansen C, Asinger RW, Black IW, Davidoff R, Erbel R, Halperin JL, Orsinelli DA, et al. Use of transesophageal echocardiography to guide cardioversion in patients with atrial fibrillation. N Engl J Med 2001;344(19):1411–1420.
   PubMed Web of Science ®Google Scholar
• Tarnowski D, Plichta L, Forkmann M, Quick S, Ulbrich S, Heidrich FM, Wiedemann S, Christoph M, Poitz DM, Wunderlich C, et al. Reduction of atrial fibrillation burden by pulmonary vein isolation leads to a decrease of CD11b expression on inflammatory cells. Europace 2017 Jan 10.
   Google Scholar
• Lim HS, Willoughby SR, Schultz C, Gan C, Alasady M, Lau DH, Leong DP, Brooks AG, Young GD, Kistler PM, et al. Effect of atrial fibrillation on atrial thrombogenesis in humans: Impact of rate and rhythm. J Am Coll Cardiol 2013;61(x):852–860.
   PubMedGoogle Scholar
• Wu N, Tong S, Xiang Y, Wu L, Xu B, Zhang Y, Ma X, Li Y, Song Z, Zhong L. Association of hemostatic markers with atrial fibrillation: A meta-analysis and meta-regression. PLoS One 2015;10(4):1–19.
   Web of Science ®Google Scholar
• Fu R, Wu S, Wu P, Qiu J. A Study of blood soluble P-selectin, fibrinogen, and von Willebrand factor levels in idiopathic and lone atrial fibrillation. Europace 2011;13(1):31–36.
   PubMed Web of Science ®Google Scholar
• Choudhury A, Chung I, Panja N, Patel J, Lip GYH. Soluble CD40 ligand, platelet surface CD40 ligand, and total platelet CD40 ligand in atrial fibrillation: Relationship to soluble p-selectin, stroke risk factors, and risk factor intervention. Chest 2008;134(3):574–581.
   PubMed Web of Science ®Google Scholar
• Pfluecke C, Berndt K, Wydra S, Tarnowski D, Barthel P, Quick S, Ulbrich S, Christoph M, Waessnig N, Speiser U, et al. Atrial fibrillation is associated with high levels of monocyte-platelet-aggregates and increased CD11b expression in patients with aortic stenosis. Thromb Haemost 2016;115(5):993–1000.
   PubMed Web of Science ®Google Scholar
• Burdess Michelsen E, Brosstad F, Fox K, Newby DE, Nimmo. F. Platelet activation in patients with peripheral vascular disease: Reproducibility and comparability of platelet markers. Thromb Res 2012;129:50–55.
   PubMed Web of Science ®Google Scholar
• Zabalgoitia M, Halperin JL, Pearce LA, Blackshear JL, Asinger RW, Hart RG. Transesophageal echocardiographic correlates of clinical risk of thromboembolism in nonvalvular atrial fibrillation. J Am Coll Cardiol 1998;31(7):1622–1626.
   PubMed Web of Science ®Google Scholar
• Lukasik M, Dworacki G, Kufel-Grabowska J, Watala C, Kozubski W. Upregulation of CD40 ligand and enhanced monocyte-platelet aggregate formation are associated with worse clinical outcome after ischaemic stroke. Thromb Haemost 2012;107(2):346–355.
   PubMed Web of Science ®Google Scholar
• Pfluecke C, Tarnowski D, Plichta L, Berndt K, Schumacher P, Ulbrich S, Forkmann M, Christoph M, Poitz DM, Wunderlich C, et al. Monocyte–platelet aggregates and CD11b expression as markers for thrombogenicity in atrial fibrillation. Clin Res Cardiol 2016;105(4):314–322.
   PubMed Web of Science ®Google Scholar
• Heeringa J, Conway DSG, Van der Kuip DAM, Hofman A, Breteler MMB, Lip GYH, Witteman JCM. A longitudinal population-based study of prothrombotic factors in elderly subjects with atrial fibrillation: The Rotterdam Study 1990-1999. Journal of Thromb Haemost 2006;4(9):1944–1949.
   PubMed Web of Science ®Google Scholar
• Conway DSG, Buggins P, Hughes E, Lip GYH. Relation of interleukin-6, C-reactive protein, and the prothrombotic state to transesophageal echocardiographic findings in atrial fibrillation. Am J Cardiol 2004;93(11):1368–1373.
   PubMed Web of Science ®Google Scholar
• Hayashi M, Takeshita K, Inden Y, Ishii H, Cheng XW, Yamamoto K, Murohara T. Platelet activation and induction of tissue factor in acute and chronic atrial fibrillation: Involvement of mononuclear cell-platelet interaction. Thromb Res 2011;128(6):e113–e118.
   PubMed Web of Science ®Google Scholar
• Makowski M, Smorąg I, Bissinger A, Grycewicz T, Masiarek K, Makowska J, Grabowicz W, Lubiński A, Baj Z. Effect of sinus rhythm restoration on platelet function in patients with lone atrial fibrillation. Int J Cardiol 2016;172(1):e22–e23.
   Web of Science ®Google Scholar
• Lim HS, Willoughby SR, Schultz C, Chakrabarty A, Alasady M, Lau DH, Roberts-Thomson KC, Worthley MI, Young GD, Sanders P. Successful catheter ablation decreases platelet activation and improves endothelial function in patients with atrial fibrillation. Heart Rhythm 2016;11(11):1912–1918.
   Web of Science ®Google Scholar
• Mahé I, Drouet L, Chassany O, Mazoyer E, Simoneau G, Knellwolf AL, Caulin C, Bergmann JF. D-dimer: A characteristic of the coagulation state of each patient with chronic atrial fibrillation. Thromb Res 2002;107(1–2):1–6.
   PubMed Web of Science ®Google Scholar
• Habara S, Dote K, Kato M, Sasaki S, Goto K, Takemoto H, Hasegawa D, Matsuda O. Prediction of left atrial appendage thrombi in non-valvular atrial fibrillation. Eur Heart J 2007;28(18):2217–2222.
   PubMed Web of Science ®Google Scholar
• Wasmer K, Köbe J, Dechering D, Milberg P, Pott C, Vogler J, Stypmann J, Waltenberger J, Mönnig G, Breithardt G, et al. CHADS(2) and CHA(2)DS (2)-VASc score of patients with atrial fibrillation or flutter and newly detected left atrial thrombus. Clin Res Cardiol Off J German Cardiac Soc 2013;102(2):139–144.
   PubMed Web of Science ®Google Scholar
• Lip GYH, Frison L, Halperin JL, Lane D a. Identifying patients at high risk for stroke despite anticoagulation: A comparison of contemporary stroke risk stratification schemes in an anticoagulated atrial fibrillation cohort. Stroke 2010;41(12):2731–2738.
   Google Scholar
• Pfluecke C, Plichta L, Tarnowski D, Forkmann M, Ulbrich S, Quick S, Heidrich FM, Wiedemann S, Christoph M, Poitz DM, et al. Association of platelet activation markers with recurrence of atrial fibrillation after pulmonary vein isolation. Platelets 2016;7104(October):1–6.
   Google Scholar
• Meus R, Son M, Sobczyk D, Undas A. Prothrombotic state in patients with a left atrial appendage thrombus of unknown origin and cerebrovascular events. Stroke J Cereb Circ 2016;47(7):1872–8.
   Google Scholar
• Wrigley BJ, Shantsila E, Tapp LD, Lip GYH. Increased formation of monocyte-platelet aggregates in ischemic heart failure. Circ Heart Fail 2013;6(1):127–135.
   PubMed Web of Science ®Google Scholar
• Kirchhofer D, Riederer MA, Baumgartner HR. Specific accumulation of circulating monocytes and polymorphonuclear leukocytes on platelet thrombi in a vascular injury model. Blood. 1997;89(4):1270–1278.
   PubMed Web of Science ®Google Scholar
• Penn MS, Topol EJ. Tissue factor, the emerging link between inflammation, thrombosis, and vascular remodeling. Circ Res 2001;89(1):1–2.
   PubMed Web of Science ®Google Scholar
• Fijnheer R, Frijns CJ, Korteweg J, Rommes H, Peters JH, Sixma JJ, Nieuwenhuis HK. The origin of P-selectin as a circulating plasma protein. Thromb Haemost 1997;77(6):1081–1085.
   PubMed Web of Science ®Google Scholar
• Gremmel T, Ay C, Riedl J, Eichelberger B, Koppensteiner R, Panzer S. Platelet-specific markers are associated with monocyte-platelet aggregate formation and thrombin generation potential in advanced atherosclerosis. Thromb Haemost 2016;115(12):1–7.
   Google Scholar
• Khzam LB, Boulahya R, Abou-Saleh H, Hachem A, Zaid Y, Merhi Y. Soluble CD40 ligand stimulates the pro-angiogenic function of peripheral blood angiogenic outgrowth cells via increased release of matrix metalloproteinase-9. PLoS One 2013;8(12):1–10.
   Web of Science ®Google Scholar
• Slupsky JR, Kalbas M, Willuweit A, Henn V, Kroczek RA, Muller-Berghaus G. Activated platelets induce tissue factor expression on human umbilical vein endothelial cells by ligation of CD40. Thromb Haemost 1998;80(6):1008–1014.
   PubMed Web of Science ®Google Scholar
• Schönbeck U, Libby P. The CD40/CD154 receptor/ligand dyad. CMLS 2001;58(1):4–43.
   PubMed Web of Science ®Google Scholar
• Shinohara H, Fukuda N, Soeki T, Takeichi N, Yui Y, Tamura Y, Oki T. Relationship between flow dynamics in the left atrium and hemostatic abnormalities in patients with nonvalvular atrial fibrillation. Jpn Heart J 1998;39(6):721–30.
   PubMedGoogle Scholar
• Igarashi Y, Kashimura K, Makiyama Y, Sato T, Ojima K, Aizawa Y. Left atrial appendage dysfunction in chronic nonvalvular atrial fibrillation is significantly associated with an elevated level of brain natriuretic peptide and a prothrombotic state. Jpn Circ J 2001;65(September):788–792.
   PubMedGoogle Scholar
• Sanfilippo J, Abascal VM, Sheehan M, Oertel LB, Harrigan P, Hughes R, Weyman E. Atrial enlargement as a consequence of atrial fibrillation. A prospective echocardiographic study. Circulation 1990;82(3):792–797.
   PubMed Web of Science ®Google Scholar
• Schneider B, Stöllberger C, Schneider B. Diagnosis of left atrial appendage thrombi by multiplane transesophageal echocardiography. Circ J 2007;71(1):122–125.
   PubMed Web of Science ®Google Scholar
• Calvo N, Mont L, Vidal B, Nadal M, Montserrat S, Andreu D, Tamborero D, Pare C, Azqueta M, Berruezo A, et al. Usefulness of transoesophageal echocardiography before circumferential pulmonary vein ablation in patients with atrial fibrillation: Is it really mandatory? Europace 2011;13(4):486–491.
   PubMed Web of Science ®Google Scholar
• Mccready JW, Nunn L, Lambiase PD, Ahsan SY, Segal OR, Rowland E, Lowe MD, Chow AW. Incidence of left atrial thrombus prior to atrial fibrillation ablation: is pre-procedural transoesophageal echocardiography mandatory? Europace 2010;12(7):927–932.
   PubMed Web of Science ®Google Scholar