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Platelets Volume 33, 2022 - Issue 5
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Letter

Refractory immune thrombocytopenia successfully treated with bortezomib in a child with 22q11.2 deletion syndrome, complicated by Evans syndrome and hypogammaglobulinemia

Francesca Conti1 Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyView further author information
,
Francesca Gottardi2 Specialty School of Paediatrics, University of Bologna, Bologna, ItalyORCID Iconhttps://orcid.org/0000-0002-2325-3671View further author information
ORCID Icon,
Mattia Moratti2 Specialty School of Paediatrics, University of Bologna, Bologna, ItalyView further author information
,
Tamara Belotti1 Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyView further author information
,
Simona Ferrari3 Medical Genetics Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyView further author information
,
Paola Selva1 Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyView further author information
,
Mirna Bassi4 Laboratory of Immuno-haematology - Laboratorio Unico Metropolitano, Azienda USL, Bologna, ItalyView further author information
,
Daniele Zama1 Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyCorrespondence[email protected]
View further author information
&
Andrea Pession1 Pediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, ItalyORCID Iconhttps://orcid.org/0000-0002-0379-9562View further author information
ORCID Icon show all
Pages 801-806 | Received 13 Jul 2021, Accepted 25 Oct 2021, Published online: 08 Feb 2022

References

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  • Grimes AB, Kim TO, Kirk SE, Flanagan J, Lambert MP, Grace RF, Despotovic JM. Refractory autoimmune cytopenias in pediatric Evans syndrome with underlying systemic immune dysregulation. Eur J Haematol Published online 2021 February 11. doi:10.1111/ejh.13600.
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  • Kohler S, Märschenz S, Grittner U, Alexander T, Hiepe F, Meisel A. Bortezomib in antibody-mediated autoimmune diseases (TAVAB): study protocol for a unicentric, non-randomised, non-placebo controlled trial. BMJ Open 2019;9(1). doi:10.1136/bmjopen-2018-024523.
  • Kruizinga MD, van Tol MJD, Bekker V, Netelenbos T, Smiers FJ, Bresters D, Jansen-Hoogendijk AM, van Ostaijen-ten Dam MM, Kollen WJW, Zwaginga JJ, et al. Risk factors, treatment, and immune dysregulation in autoimmune cytopenia after allogeneic hematopoietic stem cell transplantation in pediatric patients. Biol Blood Marrow Transplant 2018;24(4):772–778. doi:10.1016/j.bbmt.2017.12.782.
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