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Original Article

A flow cytometric assay for the study of dense granule storage and release in human platelets

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Pages 153-158 | Published online: 18 Mar 2010

References

  • Coller B S. Inherited disorders of platelet function. Haemoslasis and Thrombosis, 3rd edn., A L Bloom, C D Forbes, D P Thomas, E GD Tuddenham. Churchill Livingstone, Edinburgh 1994; 721–66
  • Gordon N, Thorn J, Cole C, Baker R. Rapid detection of hereditary and acquired platelet storage pool deficiency by flow cytometry. Br J Haematol 1995; 89: 117–23
  • Warkentin T E, Kelton J G. Aquired platelet disorders. Haemoslasis and Thrombosis, 3rd edn., A L Bloom, C D Forbes, D P Thomas, E GD Tuddenham. Churchill Livingstone, Edinburgh 1994; 767–818
  • Israels S J, McNicol A, Robertson C, Gerrard J M. Platelet storage pool deficiency: diagnosis in patients with prolonged bleeding times and normal platelet aggregation. Br J Haematol 1990; 75: 118–21
  • Da Prada M, Pletscher A. Accumulation of basic drugs in 5-hydroxytryptamine storage organelles of rabbit blood platelets. Eur J Pharmacol 1975; 32: 179–85
  • Lorez H P, Da Prada M, Rendu F, Pletscher A. Mepacrine, a tool for investigating the 5-hydroxytryptamine organelles of blood platelets by fluorescence microscopy. J Lab Clin Med 1977; 89: 200–6
  • Skaer R J, Flemans R J, McQuilkan S. Mepacrine stains the dense bodies of human platelets and not platelet lysosomes. Br J Haematol 1981; 49: 435–8
  • Rendu F, Nurden A T, Lebret M, Caen J P. Relationship between mepacrine-labelled dense body number, platelet capacity to accumulate 14C-5-HT and platelet density in the Bernard-Soulier and Hermansky-Pudlak syndromes. Thromb Haemost 1979; 42: 694–704
  • Lorez H P, Richards J G, Da Prada M, Picotti G B, Pareti F I, Capitanio A, Mannucci P M. Storage pool disease: Comparative fluorescence microscopical, cytochemical and biochemical studies on amine-storing organelles of human blood platelets. Br J Haematol 1979; 43: 297–305
  • Wall J E, Buijs-Wilts M., Arnold J T, Wang W, White M M, Jennings L K, Jackson C W. A flow cytometric assay using mepacrine for study of uptake and release of platelet dense granule contents. Br J Haematol 1995; 89: 380–5
  • Lindahl T L, Festin R, Larsson A. Studies of fibrinogen binding to platelets by flow cytometry: an improved method for studies of platelet activation. Thromb Haemost 1992; 68: 221–5
  • Kehrel B, Wierwille S, Clemetson K J, Anders O, Sleiner M, Knight C G, Farndale R W, Okuma M, Barnes M J. Glycoprotein VI is a major collagen receptor for platelet activation: it recognizes the platelet-activating quaternary structure of collagen, whereas CD36, glycoprotein IIb/IIIa, and von Willebrand factor do not. Blood 1998; 91: 491–9
  • Larsson A, Lindahl T L. Inhibition of fibrinogen binding to platelets by MK-852, a new GPIIb/IIIa antagonist. Ups J Med Sci 1994; 99: 121–30

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