Genistein ameliorates hyperuricemia-associated nephropathy in hyperuricemic mice

References

• Aslan, M., Ryan, T. M., Adler, B., Townes, T. M., Parks, D. A., Thompson, J. A., Tousson, A., Gladwin, M. T., Patel, R. P., Tarpey, M. M., & Batinic-Haberle, I. (2001). Oxygen radical inhibition of nitric oxide-dependent vascular function In sickle cell disease. Proceedings of the National Academy of Sciences of the United States of America, 98(26), 15215–15220. https://doi.org/10.1073/pnas.221292098
   PubMed Web of Science ®Google Scholar
• Canyilmaz, E., Uslu, G. H., Bahat, Z., Kandaz, M., Mungan, S., Haciislamoglu, E., Mentese, A., & Yoney, A. (2016). Comparison of the effects of melatonin and genistein on radiation–induced nephrotoxicity: Results of an experimental study. Biomedical Reports, 4(1), 45–50. https://doi.org/10.3892/br.2015.547
   PubMed Web of Science ®Google Scholar
• Chen, L., Lan, Z., Lin, Q., Mi, X., He, Y., Wei, L., Lin, Y., Zhang, Y., & Deng, X. (2013). Polydatin ameliorates renal injury by attenuating oxidative stress-related inflammatory responses in fructose-induced urate nephropathic mice. Food and Chemical Toxicology, 52, 28–35. https://doi.org/10.1016/j.fct.2012.10.037
   PubMed Web of Science ®Google Scholar
• Chen, Y., Li, C., Duan, S., Yuan, X., Liang, J., & Hou, S. (2019). Curcumin attenuates potassium oxonate-induced hyperuricemia and kidney inflammation In mice. Biomedicine & Pharmacotherapy, 118, 109195. https://doi.org/10.1016/j.biopha.2019.109195
   PubMed Web of Science ®Google Scholar
• Cheng, W. X., Huang, H., Chen, J. H., Zhang, T. T., Zhu, G. Y., Zheng, Z. T., Lin, J. T., Hu, Y. P., Zhang, Y., Bai, X. L., & Wang, Y. (2020). Genistein inhibits angiogenesis developed during rheumatoid arthritis through the IL-6/JAK2/STAT3/VEGF signalling pathway. The Journal of Orthopaedic Translation, 22(2020), 92–100. https://doi.org/10.1016/j.jot.2019.07.007
   PubMedGoogle Scholar
• Cristóbal-García, M., García-Arroyo, F. E., Tapia, E., Osorio, H., Arellano-Buendía, A. S., Madero, M., Rodríguez-Iturbe, B., Pedraza-Chaverrí, J., Correa, F., Zazueta, C., & Johnson, R. J. (2015). Renal oxidative stress induced by long-term hyperuricemia alters mitochondrial function and maintains systemic hypertension. Oxidative Medicine and Cellular Longevity, 2015, Article ID 535686. https://doi.org/10.1155/2015/535686
   Web of Science ®Google Scholar
• Cui, D., Liu, S., Tang, M., Lu, Y., Zhao, M., Mao, R., … Liu, J. (2020). Phloretin ameliorates hyperuricemia-induced chronic renal dysfunction through inhibiting NLRP3 inflammasome and uric acid reabsorption. Phytomedicine, 66, 153111. https://doi.org/10.1016/j.phymed.2019.153111
   PubMed Web of Science ®Google Scholar
• Dinour, D., Gray, N. K., Campbell, S., Shu, X., Sawyer, L., Richardson, W., … Holtzman, E. J. (2010). Homozygous SLC2A9 mutations cause severe renal hypouricemia. The Journal of the American Society of Nephrology, 21(1), 64–72. https://doi.org/10.1681/ASN.2009040406
   PubMed Web of Science ®Google Scholar
• Fukunari, A., Okamoto, K., Nishino, T., Eger, B. T., Pai, E. F., Kamezawa, M., Yamada, I., & Kato, N. (2004). Y-700 [1-[3-cyano-4-(2, 2-dimethylpropoxy) phenyl]-1H-pyrazole-4-carboxylic acid]: a potent xanthine oxidoreductase inhibitor with hepatic excretion. The Journal of Pharmacology and Experimental Therapeutics, 311(2), 519–528. https://doi.org/10.1124/jpet.104.070433
   PubMed Web of Science ®Google Scholar
• Guo, L. F., Chen, X., Lei, S. S., Li, B., Zhang, N. Y., Ge, H. Z., Yang, K., Lv, G. Y., & Chen, S. H. (2020). Effects and mechanisms of dendrobium officinalis six nostrum for treatment of hyperuricemia with hyperlipidemia. Evidence-Based Complementary and Alternative Medicine, 2020, 1–12. https://doi.org/10.1155/2020/2914019
   Web of Science ®Google Scholar
• Hanwell, M. D., Curtis, D. E., Lonie, D. C., Vandermeersch, T., Zurek, E., & Hutchison, G. R. (2012). Avogadro: An advanced semantic chemical editor, visualization, and analysis platform. J. Cheminformatics, 4(1), 1–17. https://doi.org/10.1186/1758-2946-4-17
   PubMedGoogle Scholar
• Hayyan, M., Hashim, M. A., & AlNashef, I. M. (2016). Superoxide ion: Generation and chemical implications. Chemical Reviews, 116(5), 3029–3085. https://doi.org/10.1021/acs.chemrev.5b00407
   PubMed Web of Science ®Google Scholar
• Ho, E., & Bray, T. M. (1999). Antioxidants, NF-jB activation, and diabetogenesis. Proceedings of the Society for Experimental Biology and Medicine, 222(3), 205–213. https://doi.org/10.1046/j.1525-1373.1999.d01-137.x
   PubMed Web of Science ®Google Scholar
• Hu, Q. P., Huang, X. Y., Feng, W., Chen, F. F., Yan, H. X., Zhang, X., & Zhou, Y. W. (2021). Genistein Protects Epilepsy-Induced Brain Injury Through Regulating The JAK2/STAT3 and Keap1/Nrf2 Signaling Pathways in The Developing Rats.
   Google Scholar
• Ichida, K. (2009). What lies behind serum urate concentration? Insights from genetic and genomic studies. Genome Medicine, 1(12), 1–10. https://doi.org/10.1186/gm118
   PubMedGoogle Scholar
• Ichida, K., Hosoyamada, M., Hisatome, I., Enomoto, A., Hikita, M., Endou, H., & Hosoya, T. (2004). Clinical and molecular analysis of patients with renal hypouricemia in Japan-influence of URAT1 gene on urinary urate excretion. The Journal of the American Society of Nephrology, 15(1), 164–173. https://doi.org/10.1097/01.ASN.0000105320.04395.D0
   PubMed Web of Science ®Google Scholar
• Ishaq, M., Mehmood, A., Ur Rehman, A., Dounya Zad, O., Li, J., Zhao, L., … Lian, Y. (2020). Antihyperuricemic effect of dietary polyphenol sinapic acid commonly present in various edible food plants. J. Food Biochem, 44(2), e13111. https://doi.org/10.1111/jfbc.13111
   PubMed Web of Science ®Google Scholar
• Jalili, C., Rashidi, I., Roshankhah, S., Jalili, F., & Salahshoor, M. R. (2020). Protective effect of genistein on the morphine-induced kidney disorders in male mice. Electronic Journal of General Medicine, 17(3), 1–7. https://doi.org/10.29333/ejgm/7874
   Google Scholar
• Javani, G., Alihemmati, A., Habibi, P., Yousefi, H., Karimi, P., Ebraheimi, V., & Ahmadiasl, N. (2019). The effects of genistein on renal oxidative stress and inflammation of ovariectomized rats. Jundishapur Journal of Natural Pharmaceutical Products, 14(4). https://doi.org/10.5812/jjnpp.57149
   Web of Science ®Google Scholar
• Jia, Q., Yang, R., Liu, X. F., Ma, S. F., & Wang, L. (2019). Genistein attenuates renal fibrosis in streptozotocin–induced diabetic rats. Molecular Medicine Reports, 19(1), 423–431. https://doi.org/10.3892/mmr.2018.9635
   PubMed Web of Science ®Google Scholar
• Kim, M. J., & Lim, Y. (2013). Protective effect of short-term genistein supplementation on the early stage in diabetes-induced renal damage. Mediators of Inflammation, 2013, 1–25. https://doi.org/10.1155/2013/510212
   Web of Science ®Google Scholar
• Lan, Z., Liu, J., Chen, L., Fu, Q., Luo, J., Qu, R., Kong, L., & Ma, S. (2012). Danggui-Shaoyao-San ameliorates cognition deficits and attenuates oxidative stress-related neuronal apoptosis in d-galactose-induced senescent mice. The Journal of Ethnopharmacology, 141(1), 386–395. https://doi.org/10.1016/j.jep.2012.02.050
   PubMed Web of Science ®Google Scholar
• Lee, J. I., & Burckart, G. J. (1998). Nuclear factor kappa B: Important transcription factor and therapeutic target. The Journal of Clinical Pharmacology, 38(11), 981–993. https://doi.org/10.1177/009127009803801101
   PubMed Web of Science ®Google Scholar
• Lee, Y. S., Kim, S. H., Yuk, H. J., & Kim, D. S. (2018). DKB114, a mixture of Chrysanthemum indicum linne flower and Cinnamomum cassia (L.) J. presl bark extracts, improves hyperuricemia through inhibition of xanthine oxidase activity and increasing urine excretion. Nutrients, 10(10), 1381. https://doi.org/10.3390/nu10101381
   PubMed Web of Science ®Google Scholar
• Li, Y., Zhao, Z., Luo, J., Jiang, Y., Li, L., Chen, Y., Zhang, L., Huang, Q., Cao, Y., Zhou, P., & Pang, J. (2021). Apigenin ameliorates hyperuricemic nephropathy by inhibiting URAT1 and GLUT9 and relieving renal fibrosis via the Wnt/β-catenin pathway. Phytomedicine, 87, 153585. https://doi.org/10.1016/j.phymed.2021.153585
   PubMed Web of Science ®Google Scholar
• Liu, R., Han, C., Wu, D., Xia, X., Gu, J., Guan, H., … Teng, W. (2015). Prevalence of hyperuricemia and gout In mainland China from 2000 to 2014: A systematic review and meta-analysis. BioMed Research International, 2015, 1–17. https://doi.org/10.1155/2015/762820
   Web of Science ®Google Scholar
• Mandal, A. K., & Mount, D. B. (2015). The molecular physiology of uric acid homeostasis. The Annual Review of Physiology, 77(1), 323–345. https://doi.org/10.1146/annurev-physiol-021113-170343
   PubMedGoogle Scholar
• Mehmood, A., Ishaq, M., Zhao, L., Safdar, B., Rehman, A. U., Munir, M., Raza, A., Nadeem, M., Iqbal, W., & Wang, C. (2019a). Natural compounds with xanthine oxidase inhibitory activity: A review. Chemical Biology & Drug Design, 93(4), 387–418. https://doi.org/10.1111/cbdd.13437
   PubMed Web of Science ®Google Scholar
• Mehmood, A., Rehman, A. U., Ishaq, M., Zhao, L., Li, J., Usman, M., Zhao, L., Rehman, A., Zad, O. D., & Wang, C. (2020a). In vitro and in silico xanthine oxidase inhibitory activity of selected phytochemicals widely present in various edible plants. Combinatorial Chemistry & High Throughput Screening, 23(9), 917–930. https://doi.org/10.2174/1386207323666200428075224
   PubMed Web of Science ®Google Scholar
• Mehmood, A., Zhao, L., Ishaq, M., Safdar, B., Wang, C., & Nadeem, M. (2018). Optimization of total phenolic contents, antioxidant, and invitro xanthine oxidase inhibitory activity of sunflower head. Journal of Food, 16(1), 957–964. https://doi.org/10.1080/19476337.2018.1504121
   Google Scholar
• Mehmood, A., Zhao, L., Ishaq, M., Usman, M., Zad, O. D., Hossain, I., Raka, R. N., Naveed, M., Zhao, L., Wang, C., & Nadeem, M. (2020b). Uricostatic and uricosuric effect of grapefruit juice in potassium oxonate-induced hyperuricemic mice. The Journal of Food Biochemistry, 23(9), 917–930. https://doi.org/10.2174/1386207323666200428075224
   Google Scholar
• Mehmood, A., Zhao, L., Ishaq, M., Xin, W., Zhao, L., Wang, C., Hossen, I., Zhang, H., Lian, Y., & Xu, M. (2020c). Anti-hyperuricemic potential of stevia (Stevia rebaudiana bertoni) residue extract in hyperuricemic mice. Food & Function, 11(7), 6387–6406. https://doi.org/10.1039/C9FO02246E
   PubMedGoogle Scholar
• Mehmood, A., Zhao, L., Ishaq, M., Zad, O. D., Zhao, L., Wang, C., Usman, M., Lian, Y., & Xu, M. (2020d). Renoprotective effect of stevia residue extract on adenine-induced chronic kidney disease in mice. Journal of Functional Foods, 72, 103983. https://doi.org/10.1016/j.jff.2020.103983
   Web of Science ®Google Scholar
• Mehmood, A., Zhao, L., Wang, C., Hossen, I., & Nadeem, M. (2020e). Stevia residue extract alone and combination with allopurinol attenuate hyperuricemia in fructose–PO-induced hyperuricemic mice. J. Food Biochem, 44(1), e13087. https://doi.org/10.1111/jfbc.13087
   PubMed Web of Science ®Google Scholar
• Mehmood, A., Zhao, L., Wang, C., Nadeem, M., Raza, A., Ali, N., & Shah, A. A. (2019b). Management of hyperuricemia through dietary polyphenols as a natural medicament: A comprehensive review. Critical Reviews in Food Science and Nutrition, 59(9), 1433–1455. https://doi.org/10.1080/10408398.2017.1412939
   PubMed Web of Science ®Google Scholar
• Müller, d. S., Coelho, C. M., Araújo, G. B., Saúde-Guimarães, M. C. D. P. M., & A, D. (2019). Lychnophora pinaster ethanolic extract and its chemical constituents ameliorate hyperuricemia and related inflammation. The Journal of Ethnopharmacology, 242, 112040. https://doi.org/10.1016/j.jep.2019.112040
   PubMed Web of Science ®Google Scholar
• Nigam, S. K., Bush, K. T., & Bhatnagar, V. (2007). Drug and toxicant handling by the OAT organic anion transporters In the kidney and other tissues. Nature Reviews Nephrology, 3(8), 443–448. https://doi.org/10.1038/ncpneph0558
   Google Scholar
• Ning, Y., Chen, J., Shi, Y., Song, N., Yu, X., Fang, Y., & Ding, X. (2020). Genistein ameliorates renal fibrosis through regulation snail via m6A RNA demethylase ALKBH5. Frontiers in Pharmacology, 11. https://doi.org/10.3389/fphar.2020.579265
   Web of Science ®Google Scholar
• Nusse, R., & Clevers, H. (2017). Wnt/β-catenin signaling, disease, and emerging therapeutic modalities. Cell, 169(6), 985–999. https://doi.org/10.1016/j.cell.2017.05.016
   PubMed Web of Science ®Google Scholar
• Osarogiagbon, U. R., Choong, S., Belcher, J. D., Vercellotti, G. M., Paller, M. S., & Hebbel, R. P. (2000). Reperfusion injury pathophysiology in sickle transgenic mice. Blood, 96(1), 314–320. https://doi.org/10.1182/blood.V96.1.314
   PubMed Web of Science ®Google Scholar
• Pan, J., Shi, M., Li, L., Liu, J., Guo, F., Feng, Y., Ma, L., & Fu, P. (2019). Pterostilbene, a bioactive component of blueberries, alleviates renal fibrosis in a severe mouse model of hyperuricemic nephropathy. Biomedicine & Pharmacotherapy, 109, 1802–1808. https://doi.org/10.1016/j.biopha.2018.11.022
   PubMed Web of Science ®Google Scholar
• Pan, J., Zhang, C., Shi, M., Guo, F., Liu, J., Li, L., Ren, Q., Tao, S., Tang, M., Ye, H., & Fu, P. (2021). Ethanol extract of Liriodendron chinense (Hemsl.) Sarg barks attenuates hyperuricemic nephropathy by inhibiting renal fibrosis and inflammation in mice. The Journal of Ethnopharmacology, 264, 113278. https://doi.org/10.1016/j.jep.2020.113278
   PubMed Web of Science ®Google Scholar
• Pang, M., Fang, Y., Chen, S., Zhu, X., Shan, C., Su, J., Yu, J., Li, B., Yang, Y., Chen, B., & Lv, G. (2017). Gypenosides inhibits xanthine oxidoreductase and ameliorates urate excretion in hyperuricemic rats induced by high cholesterol and high fat food (lipid emulsion). Medical Science Monitor: International Medical Journal of Experimental and Clinical Research, 23(2017), 1129–1140. https://doi.org/10.12659/msm.903217
   PubMedGoogle Scholar
• Pavese, J. M., Farmer, R. L., & Bergan, R. C. (2010). Inhibition of cancer cell invasion and metastasis by genistein. Cancer and Metastasis Reviews, 29(3), 465–482. https://doi.org/10.1007/s10555-010-9238-z
   PubMed Web of Science ®Google Scholar
• Qian, X., Wang, X., Luo, J., Liu, Y., Pang, J., Zhang, H., Xu, Z., Xie, J., Jiang, X., & Ling, W. (2019). Hypouricemic and nephroprotective roles of anthocyanins in hyperuricemic mice. Food & Function, 10(2), 867–878. https://doi.org/10.1039/C8FO02124D
   PubMed Web of Science ®Google Scholar
• Rehman, K., Ali, M. B., & Akash, M. S. H. (2019). Genistein enhances the secretion of glucagon-like peptide-1 (GLP-1) via downregulation of inflammatory responses. Biomedicine & Pharmacotherapy, 112, 108670. https://doi.org/10.1016/j.biopha.2019.108670
   PubMed Web of Science ®Google Scholar
• Robinson, P. C. (2018). Gout–An update of aetiology, genetics, co-morbidities and management. Maturitas, 118, 67–73. https://doi.org/10.1016/j.maturitas.2018.10.012
   PubMed Web of Science ®Google Scholar
• Schmidt, H. M., Kelley, E. E., & Straub, A. C. (2018). The impact of xanthine oxidase (XO) on hemolytic diseases. Redox Biology, 21(2019), 101072. https://doi.org/10.1016/j.redox.2018.101072
   PubMedGoogle Scholar
• Stephenson, T. J., Setchell, K. D. R., Kendall, C. W. C., Jenkins, D. J. A., Anderson, J. W., & Fanti, P. (2005). Effect of soy protein-rich diet on renal function in young adults with insulin-dependent diabetes mellitus. Journal of Clinical Nephrology, 64(1), 1–11. https://doi.org/10.5414/cnp64001
   PubMed Web of Science ®Google Scholar
• Sung, M. J., Kim, D. H., Jung, Y. J., Kang, K. P., Lee, A. S., Lee, S., … Park, S. K. (2008). Genistein protects the kidney from cisplatin-induced injury. Kidney International, 74(12), 1538–1547. https://doi.org/10.1038/ki.2008.409
   PubMed Web of Science ®Google Scholar
• Tan, J., Wan, L., Chen, X., Li, X., Hao, X., Li, X., … Ding, H. (2019). Conjugated linoleic acid ameliorates high fructose-induced hyperuricemia and renal inflammation in rats via NLRP3 inflammasome and TLR4 signaling pathway. Molecular Nutrition & Food Research, 63(12), 1801402. https://doi.org/10.1002/mnfr.201801402
   PubMed Web of Science ®Google Scholar
• Tang, D. H., Ye, Y. S., Wang, C. Y., Li, Z. L., Zheng, H., & Ma, K. L. (2017). Potassium oxonate induces acute hyperuricemia In the tree shrew (tupaia belangeri chinensis). Experimental Animals, 66(3), 209–216. https://doi.org/10.1538/expanim.16-0096
   PubMed Web of Science ®Google Scholar
• Wang, M., Chen, D. Q., Chen, L., Cao, G., Zhao, H., Liu, D., Vaziri, N. D., Guo, Y., & Zhao, Y. Y. (2018a). Novel inhibitors of the cellular RAS components, poricoic acids, target Smad3 phosphorylation and Wnt/β-catenin pathway against renal fibrosis. The British Journal of Pharmacology, 175(13), 1384–1395. https://doi.org/10.1111/bph.14333
   Web of Science ®Google Scholar
• Wang, M., Chen, D. Q., Chen, L., Liu, D., Zhao, H., Zhang, Z. H., Vaziri, N. D., Guo, Y., Zhao, Y. Y., & Cao, G. (2018b). Novel RAS inhibitors poricoic acid ZG and poricoic acid ZH attenuate renal fibrosis via a Wnt/β-catenin pathway and targeted phosphorylation of smad3 signaling. Journal of Agricultural and Food Chemistry, 66(8), 1828–1842. https://doi.org/10.1021/acs.jafc.8b00099
   PubMed Web of Science ®Google Scholar
• Wang, X., Wang, C. P., Hu, Q. H., Lv, Y. Z., Zhang, X., OuYang, Z., & Kong, L. D. (2010). The dual actions of sanmiao wan as a hypouricemic agent: Down-regulation of hepatic XOD and renal mURAT1 in hyperuricemic mice. The Journal of Ethnopharmacology, 128(1), 107–115. https://doi.org/10.1016/j.jep.2009.12.035
   PubMed Web of Science ®Google Scholar
• Xiao, L., Zhou, D., Tan, R. J., Fu, H., Zhou, L., Hou, F. F., & Liu, Y. (2016). Sustained activation of Wnt/β-catenin signaling drives AKI to CKD progression. The Journal of the American Society of Nephrology, 27(6), 1727–1740. https://doi.org/10.1681/ASN.2015040449
   PubMed Web of Science ®Google Scholar
• Xu, Y., Cao, X., Zhao, H., Yang, E., Wang, Y., Cheng, N., & Cao, W. (2021). Impact of Camellia japonica bee pollen polyphenols on hyperuricemia and gut microbiota in potassium oxonate-induced mice. Nutrients, 13(8), 2665. https://doi.org/10.3390/nu13082665
   PubMed Web of Science ®Google Scholar
• Yang, H., Bai, W., Gao, L., Jiang, J., Tang, Y., Niu, Y., Lin, H., & Li, L. (2018). Mangiferin alleviates hypertension induced by hyperuricemia via increasing nitric oxide releases. Journal of Pharmacological Sciences, 137(2), 154–161. https://doi.org/10.1016/j.jphs.2018.05.008
   PubMed Web of Science ®Google Scholar
• Yin, Y., Li, X., Sha, X., Xi, H., Li, Y. F., Shao, Y., Mai, J., Virtue, A., Lopez-Pastrana, J., Meng, S., & Tilley, D. G. (2015). Early hyperlipidemia promotes endothelial activation via a caspase-1-sirtuin 1 pathway. Arteriosclerosis, Thrombosis, and Vascular Biology, 35(4), 804–816. https://doi.org/10.1161/ATVBAHA.115.305282
   PubMed Web of Science ®Google Scholar
• Yong, T., Zhang, M., Chen, D., Shuai, O., Chen, S., Su, J., Yong, T., Zhang, M., Chen, D., Shuai, O., Chen, S., Su, J., Jiao, C., Feng, D., & Xie, Y. (2016). Actions of water extract from Cordyceps militaris in hyperuricemic mice induced by potassium oxonate combined with hypoxanthine. Journal of Ethnopharmacology, 194, 403–411. https://doi.org/10.1016/j.jep.2016.10.001
   PubMed Web of Science ®Google Scholar
• Zeng, Y., Zhang, R., Wu, J., Liu, M., Peng, W., Yu, X., & Yang, X. (2012). Organic anion transporter 1 (OAT1) involved in renal cell transport of aristolochic acid. Human & Experimental Toxicology, 31(8), 759–770. https://doi.org/10.1177/0960327111424302
   PubMed Web of Science ®Google Scholar
• Zhang, Y., & Chen, H. (2011). Genistein attenuates WNT signaling by up-regulating sFRP2 In a human colon cancer cell line. Experimental Biology and Medicine, 236(6), 714–722. https://doi.org/10.1258/ebm.2011.010347
   PubMed Web of Science ®Google Scholar
• Zhou, Q., Jiang, S., Zhou, T., Tian, J., & Chen, J. (2017). A study comparing the safety and efficacy of febuxostat, allopurinol, and benzbromarone in Chinese gout patients: A retrospective cohort study. International Journal of Clinical Pharmacology and Therapeutics, 55(2), 163. https://doi.org/10.5414/CP202629
   PubMed Web of Science ®Google Scholar
• Zhou, Y., Zhao, M., Pu, Z., Xu, G., & Li, X. (2018). Relationship between oxidative stress and inflammation in hyperuricemia: Analysis based on asymptomatic young patients with primary hyperuricemia. Medicine, 97(49), e13108. https://doi.org/10.1097/MD.0000000000013108
   PubMed Web of Science ®Google Scholar
• Zuo, Y., & Liu, Y. (2018). New insights into the role and mechanism of Wnt/β-catenin signalling in kidney fibrosis. Nephrology, 23, 38–43. https://doi.org/10.1111/nep.13472
   PubMed Web of Science ®Google Scholar