Antioxidant and anti-inflammatory activities of Gynura procumbens flowers extract through suppressing LPS-induced MAPK/NF-κB signalling pathways

References

• Ahmad, M. H., Fatima, M., Hossain, M., & Mondal, A. C. (2018). Evaluation of naproxen-induced oxidative stress, hepatotoxicity and in-vivo genotoxicity in male Wistar rats. Journal of Pharmaceutical Analysis, 8(6), 400–406. https://doi.org/10.1016/j.jpha.2018.04.002
   PubMed Web of Science ®Google Scholar
• Alam, M. B., Chowdhury, N. S., Sohrab, M. H., Rana, M. S., Hasan, C. M., & Lee, S.-H. (2020). Cerevisterol alleviates inflammation via suppression of MAPK/NF-κB/AP-1 and activation of the Nrf2/HO-1 signaling cascade. Biomolecules, 10(2), 199. https://doi.org/10.3390/biom10020199
   PubMed Web of Science ®Google Scholar
• Ashraf, K. (2019). An updated phytochemical and pharmacological review on Gynura procumbens. Asian Journal of Pharmaceutical and Clinical Research, 12, 9–14. https://doi.org/10.22159/ajpcr.2019.v12i4.28996
   Google Scholar
• Baek, K.-S., Hong, Y. D., Kim, Y., Sung, N. Y., Yang, S., Lee, K. M., Park, J. Y., Park, J. S., Rho, H. S., & Shin, S. S. (2015). Anti-inflammatory activity of AP-SF, a ginsenoside-enriched fraction, from Korean ginseng. Journal of Ginseng Research, 39(2), 155–161. https://doi.org/10.1016/j.jgr.2014.10.004
   PubMed Web of Science ®Google Scholar
• Bai, M., Han, W., Zhao, X., Wang, Q., Gao, Y., & Deng, S. (2018). Glycosaminoglycans from a sea snake (Lapemis curtus): extraction, structural characterization and antioxidant activity. Marine Drugs, 16(5), 170. https://doi.org/10.3390/md16050170
   PubMedGoogle Scholar
• Bayazid, A. B., Chun, E. M., Al Mijan, M., Park, S. H., Moon, S.-K., Lim, B. O. J. F., & Immunology, A. (2021). Anthocyanins profiling of bilberry (Vaccinium myrtillus L.) extract that elucidates antioxidant and anti-inflammatory effects. Food and Agricultural Immunology, 32(1), 713–726. https://doi.org/10.1080/09540105.2021.1986471
   Web of Science ®Google Scholar
• Bayazid, A. B., Park, S. H., Kim, J. G., & Lim, B. O. (2020). Green chicory leaf extract exerts anti-inflammatory effects through suppressing LPS-induced MAPK/NF-κB activation and hepatoprotective activity in vitro. Food and Agricultural Immunology, 31(1), 513–532. https://doi.org/10.1080/09540105.2020.1742667
   Web of Science ®Google Scholar
• Cao, M.-y., Hu, J.-w., Gu, Z., Xiong, W., Wu, L., Xu, J.-g., & Wu, L.-y. (2021). Purification of four caffeoylquinic acid derivatives from the flowers of Gynura procumbens by HSCCC. Journal of Chromatographic Science, 59(10), 971–977. https://doi.org/10.1093/chromsci/bmab036
   PubMedGoogle Scholar
• Cao, M.-y., Wu, J., Wu, L., Gu, Z., Xie, C.-q., Wu, L.-y., Hu, J.-w., & Xu, G.-z. (2022). Separation of three flavonoid glycosides from Polygonum multiflorum Thunb. leaves using HSCCC and their antioxidant activities. European Food Research and Technology, 248(1), 129–139. https://doi.org/10.1007/s00217-021-03865-0
   Web of Science ®Google Scholar
• Cao, Y., Li, F., Luo, Y., Zhang, L., Lu, S., Xing, R., Yan, B., Zhang, H., & Hu, W. (2019). 20-Hydroxy-3-oxolupan-28-oic acid attenuates inflammatory responses by regulating PI3K–AKT and MAPKs signaling pathways in LPS-stimulated RAW264. 7 macrophages. Molecules, 24(3), 386. https://doi.org/10.3390/molecules24030386
   PubMedGoogle Scholar
• Cheng, B. C.-Y., Ma, X.-Q., Kwan, H.-Y., Tse, K.-W., Cao, H.-H., Su, T., Shu, X., Wu, Z.-z., & Yu, Z.-l. (2014). A herbal formula consisting of Rosae Multiflorae Fructus and Lonicerae Japonicae Flos inhibits inflammatory mediators in LPS-stimulated RAW 264.7 macrophages. Journal of Ethnopharmacology, 153(3), 922–927. https://doi.org/10.1016/j.jep.2014.02.029
   PubMedGoogle Scholar
• Endale, M., Kim, T.-H., Kwak, Y.-S., Kim, N.-M., Kim, S.-H., Cho, J. Y., Yun, B.-S., & Rhee, M.-H. (2017). Torilin inhibits inflammation by limiting TAK1-mediated MAP kinase and NF-κB activation. Mediators of Inflammation, 2017. https://doi.org/10.1155/2017/7250968
   Google Scholar
• Gong, G., Xie, F., Zheng, Y., Hu, W., Qi, B., He, H., Dong, T. T., & Tsim, K. W. (2020). The effect of methanol extract from Saussurea involucrata in the lipopolysaccharide-stimulated inflammation in cultured RAW 264.7 cells. Journal of Ethnopharmacology, 251, 112532. https://doi.org/10.1016/j.jep.2019.112532
   PubMedGoogle Scholar
• Gong, J., Chu, B., Gong, L., Fang, Z., Zhang, X., Qiu, S., Wang, J., Xiang, Y., Xiao, G., & Yuan, H. J. A. (2019). Comparison of phenolic compounds and the antioxidant activities of fifteen Chrysanthemum morifolium Ramat cv.‘Hangbaiju’in China. Antioxidants, 8(8), 325. https://doi.org/10.3390/antiox8080325
   Google Scholar
• Gong, L.-B., Wen, T., Li, Z., Xin, X., Che, X.-F., Wang, J., Liu, Y.-P., & Qu, X.-J. (2019). DYNC1I1 promotes the proliferation and migration of gastric cancer by up-regulating IL-6 expression. Frontiers in Oncology, 9(article 491), 1–18. doi:10.3389/fonc.2019.00491
   PubMedGoogle Scholar
• He, M. T., Park, H. S., Kim, Y. S., Lee, A. Y., & Cho, E. J. (2021). Protective effect of membrane-free stem cells against lipopolysaccharide and interferon-gamma-stimulated inflammatory responses in RAW 264.7 macrophages. International Journal of Molecular Sciences, 22(13), 6894. https://doi.org/10.3390/ijms22136894
   PubMedGoogle Scholar
• Hu, J.-W., Wu, J., Zhang, Y., Huang, B.-H., Fu, J.-P., Wu, L., & Xu, G. (2019). Chemical constituents of the stems of Gynura procumbens. Chemistry of Natural Compounds, 55(3), 583–585. https://doi.org/10.1007/s10600-019-02751-2
   Google Scholar
• Huang, X.-L., Li, X.-J., Qin, Q.-F., Li, Y.-S., Zhang, W. K., & Tang, H.-B. (2019). Anti-inflammatory and antinociceptive effects of active ingredients in the essential oils from Gynura procumbens, a traditional medicine and a new and popular food material. Journal of Ethnopharmacology, 239, 111916. https://doi.org/10.1016/j.jep.2019.111916
   PubMed Web of Science ®Google Scholar
• Hwang, S. J., Kim, Y.-W., Park, Y., Lee, H.-J., & Kim, K.-W. (2014). Anti-inflammatory effects of chlorogenic acid in lipopolysaccharide-stimulated RAW 264.7 cells. Inflammation Research, 63(1), 81–90. https://doi.org/10.1007/s00011-013-0674-4
   PubMed Web of Science ®Google Scholar
• Izuta, H., Narahara, Y., Shimazawa, M., Mishima, S., Kondo, S.-i., Hara, H. J. B., & Bulletin, P. (2009). 1, 1-diphenyl-2-picrylhydrazyl radical scavenging activity of bee products and their constituents determined by ESR. Biological and Pharmaceutical Bulletin, 32(12), 1947–1951. https://doi.org/10.1248/bpb.32.1947
   PubMedGoogle Scholar
• Jin, Y., Kim, H. P., Chi, M., Ifedigbo, E., Ryter, S. W., & Choi, A. M. (2008). Deletion of caveolin-1 protects against oxidative lung injury via up-regulation of heme oxygenase-1. American Journal of Respiratory Cell and Molecular Biology, 39(2), 171–179. https://doi.org/10.1165/rcmb.2007-0323OC
   PubMed Web of Science ®Google Scholar
• Kaewseejan, N., Sutthikhum, V., & Siriamornpun, S. (2015). Potential of Gynura procumbens leaves as source of flavonoid-enriched fractions with enhanced antioxidant capacity. Journal of Functional Foods, 12, 120–128. https://doi.org/10.1016/j.jff.2014.11.001
   Web of Science ®Google Scholar
• Kim, M.-S., & Kim, S.-H. (2011). Inhibitory effect of astragalin on expression of lipopolysaccharide-induced inflammatory mediators through NF-κB in macrophages. Archives of Pharmacal Research, 34(12), 2101–2107. https://doi.org/10.1007/s12272-011-1213-x
   PubMed Web of Science ®Google Scholar
• Klimontov, V. V., Korbut, A. I., Orlov, N. B., Dashkin, M. V., & Konenkov, V. I. (2020). Multiplex bead array assay of a panel of circulating cytokines and growth factors in patients with albuminuric and non-albuminuric diabetic kidney disease. Journal of Clinical Medicine, 9(9), 3006. https://doi.org/10.3390/jcm9093006
   PubMedGoogle Scholar
• Ko, M.-J., Nam, H.-H., & Chung, M.-S. (2020). Subcritical water extraction of bioactive compounds from Orostachys japonicus A. Berger (Crassulaceae). Scientific Reports, 10(1), 1–10. https://doi.org/10.1038/s41598-019-56847-4
   PubMed Web of Science ®Google Scholar
• Kumar, S., Sharma, S., & Vasudeva, N. (2017). Review on antioxidants and evaluation procedures. Chinese Journal of Integrative Medicine, 1–12. doi:10.1007/s11655-017-2414-z
   Google Scholar
• Li, X.-Y., Zhang, M.-T., Mu, Y.-M., Li, T.-T., Yang, Y.-L., Zeng, Z.-X., Li, Y.-S., & Zhou, H.-B. (2015). Quantitative analysis of multiple-components by a single marker of chlorogenic acid from Gynura procumbens (Lour.) Merr. Chinese Journal of Hospital Pharmacy, 35(22), 5. doi:10.13286/j.cnki.chinhosppharmacyj.2015.22.07
   Google Scholar
• Lu, Q., Sun, Y., Shu, Y., Tan, S., Yin, L., Guo, Y., & Tang, L. (2016). HSCCC separation of the two iridoid glycosides and three phenolic compounds from Veronica ciliata and their in vitro antioxidant and anti-hepatocarcinoma activities. Molecules, 21(9), 1234. https://doi.org/10.3390/molecules21091234
   PubMedGoogle Scholar
• Murugaiyah, V., Saeed, M. A. A., Kuong, Y.-M., Murugesu, K., Parasuraman, S., Asmawi, M. Z., & Sadikun, A. (2018). Lipid-lowering effect of hydroalcoholic extracts of Gynura procumbens in chemical-and high-fat diet-induced hyperlipidemic rats. Pharmacognosy Magazine, 14(55), 184. https://doi.org/10.4103/pm.pm_451_17
   Google Scholar
• Murugesu, K., Saghir, S. A. M., Sadikun, A., Khaw, K.-Y., & Murugaiyah, V. J. A. C. (2021). Exploiting column chemistry for chromatographic separation and quantification of caffeoylquinic acids in Gynura procumbens. Acta Chromatographica, 33(2), 170–178. https://doi.org/10.1556/1326.2020.00690
   Google Scholar
• Mustafa, I., Chin, N. L., Fakurazi, S., & Palanisamy, A. (2019). Comparison of phytochemicals, antioxidant and anti-inflammatory properties of sun-, oven-and freeze-dried ginger extracts. Foods, 8(10), 456. https://doi.org/10.3390/foods8100456
   PubMedGoogle Scholar
• Ning, T. J., Yusoff, S. D., Jubri, Z., Buang, F., Song, T. Z., Budiono, A., Jantan, I., Dianita, R., Kumolosasi, E., & Azmi, N. (2019). Inhibitory effects of Gynura procumbens ethanolic extract on nitric oxide production and inducible nitric oxide synthase (iNOS) protein expression in macrophages. Sains Malaysiana, 48(8), 1737–1744. https://doi.org/10.17576/jsm-2019-4808-20
   Web of Science ®Google Scholar
• Park, C.-H., Min, S.-Y., Yu, H.-W., Kim, K., Kim, S., Lee, H.-J., Kim, J.-H., & Park, Y.-J. (2020). Effects of apigenin on RBL-2H3, RAW264. 7, and HaCaT cells: Anti-allergic, anti-inflammatory, and skin-protective activities. International Journal of Molecular Sciences, 21(13), 4620. https://doi.org/10.3390/ijms21134620
   PubMedGoogle Scholar
• Peng, Y., Hu, M., Lu, Q., Tian, Y., He, W., Chen, L., Wang, K., Pan, S. J. F., & Immunology, A. (2019). Flavonoids derived from Exocarpium Citri Grandis inhibit LPS-induced inflammatory response via suppressing MAPK and NF-κB signalling pathways. Food and Agricultural Immunology, 30(1), 564–580. https://doi.org/10.1080/09540105.2018.1550056
   Web of Science ®Google Scholar
• Rosidah, Y. M., Sadikun, A., & Asmawi, M. (2008). Antioxidant potential of Gynura procumbens. Pharmaceutical Biology, 46(9), 616–625. https://doi.org/10.1080/13880200802179642
   Web of Science ®Google Scholar
• Sava, A., Buron, F., Routier, S., Panainte, A., Bibire, N., Constantin, S. M., Lupașcu, F. G., Focșa, A. V., & Profire, L. (2021). Design, synthesis, in silico and in vitro studies for new nitric oxide-releasing indomethacin derivatives with 1, 3, 4-oxadiazole-2-thiol scaffold. International Journal of Molecular Sciences, 22(13), 7079. https://doi.org/10.3390/ijms22137079
   PubMedGoogle Scholar
• Seo, Y.-J., Lee, K.-T., Rho, J.-R., & Choi, J.-H. (2015). Phorbaketal A, isolated from the marine sponge Phorbas sp., exerts its anti-inflammatory effects via NF-κB inhibition and heme oxygenase-1 activation in lipopolysaccharide-stimulated macrophages. Marine Drugs, 13(11), 7005–7019. https://doi.org/10.3390/md13117005
   PubMedGoogle Scholar
• Shin, J. Y., Kang, J. S., Byun, H. W., & Ahn, E. K. (2017). Regulatory effects and molecular mechanism of Trigonostemon reidioides on lipopolysaccharide-induced inflammatory responses in RAW264. 7 cells. Molecular Medicine Reports, 16(4), 5137–5142. https://doi.org/10.3892/mmr.2017.7297
   PubMedGoogle Scholar
• Sun, L.-P., Shi, F.-F., Zhang, W.-W., Zhang, Z.-H., & Wang, K. (2020). Antioxidant and anti-inflammatory activities of safflower (Carthamus tinctorius L.) honey extract. Foods, 9(8), 1039. https://doi.org/10.3390/foods9081039
   PubMed Web of Science ®Google Scholar
• Taira, J., Uehara, M., Tsuchida, E., Ohmine, W. J. J. o. a., & chemistry, f. (2014). Inhibition of the β-catenin/Tcf signaling by caffeoylquinic acids in sweet potato leaf through down regulation of the Tcf-4 transcription. Journal of Agricultural and Food Chemistry, 62(1), 167–172. https://doi.org/10.1021/jf404411r
   PubMedGoogle Scholar
• Tan, H.-L., Chan, K.-G., Pusparajah, P., Lee, L.-H., & Goh, B.-H. (2016). Gynura procumbens: An overview of the biological activities. Frontiers in Pharmacology, 7(article 52), 1–14. doi:10.3389/fphar.2016.00052
   PubMedGoogle Scholar
• Tantowi, N. A. C. A., Mohamed, S., Lau, S. F., & Hussin, P. (2020). Comparison of diclofenac with apigenin-glycosides rich Clinacanthus nutans extract for amending inflammation and catabolic protease regulations in osteoporotic-osteoarthritis rat model. DARU Journal of Pharmaceutical Sciences, 28(2), 443–453. https://doi.org/10.1007/s40199-020-00343-y
   Google Scholar
• Xiao, Y., Zheng, Y., Wu, S., Zhang, E.-H., Chen, Z., Liang, P., Huang, X., Yang, Z.-H., Ng, I.-S., & Chen, B.-Y. (2015). Pyrosequencing reveals a core community of anodic bacterial biofilms in bioelectrochemical systems from China. Frontiers in Microbiology, 6, 1410. https://doi.org/10.3389/fmicb.2015.01410
   PubMed Web of Science ®Google Scholar
• Yang, F., Qi, Y., Liu, W., Li, J., Wang, D., Fang, L., & Zhang, Y. (2019). Separation of five flavonoids from aerial parts of Salvia miltiorrhiza bunge using HSCCC and their antioxidant activities. Molecules, 24(19), 3448. https://doi.org/10.3390/molecules24193448
   PubMedGoogle Scholar
• Yang, Y., Ding, Z., Wang, Y., Zhong, R., Feng, Y., Xia, T., Xie, Y., Yang, B., Sun, X., & Shu, Z. (2020). Systems pharmacology reveals the mechanism of activity of Physalis alkekengi L. var. franchetii against lipopolysaccharide-induced acute lung injury. Journal of Cellular and Molecular Medicine, 24(9), 5039–5056. https://doi.org/10.1111/jcmm.15126
   PubMedGoogle Scholar
• Yang, Y., Wu, J.-J., Cheng, C.-D., Bao, D.-J., Dong, Y.-F., Li, D.-X., Niu, W.-X., Zhou, C.-X., & Niu, C.-S. (2018). G-protein-coupled receptor kinase-5 promotes glioblastoma progression by targeting the nuclear factor kappa B pathway. American Journal of Translational Research, 10(11), 3370–3384.
   PubMedGoogle Scholar
• Yin, L., Wei, L., Fu, R., Ding, L., Guo, Y., Tang, L., & Chen, F. (2014). Antioxidant and hepatoprotective activity of Veronica ciliata Fisch. extracts against carbon tetrachloride-induced liver injury in mice. Molecules, 19(6), 7223–7236. https://doi.org/10.3390/molecules19067223
   PubMed Web of Science ®Google Scholar