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AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 19, 2007 - Issue 9
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Original Articles

What should South African HIV vaccine trials do about social harms?

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Pages 1110-1117 | Published online: 06 Aug 2010

References

  • Allen , M. 2001 . Trial-related discrimination in HIV vaccine clinical trials . AIDS Research and Human Retroviruses , 17 : 667 – 668 .
  • Baleta , A. 1999 . South Africa faces an AIDS crisis as government health campaigns fail . Lancet , 353 : 653
  • Bartholow , B.N. , Buchbinder , S. , Goli , V. , Celum , C. , Koblin , B. , Marmor , M. , et al. . ( 2002 ). HIV risk behaviour change over 24 months of follow-up in a Phase-III HIV vaccine efficacy trial . Abstract of paper presented at XIV International AIDS Conference , Barcelona , August .
  • Bartholow , B. , Buchbinder , S. , Celum , C. , Goli , V. , Koblin , B. Para , M. 2005 . HIV sexual risk behaviour over 36 months of follow-up in the world's first HIV vaccine efficacy trial . Journal of Acquired Immune Deficiency Syndromes , 39 : 90 – 101 .
  • Belshe , R.B. , Stevens , C. , Gorse , G.J. , Buchbinder , S. , Weinhold , K. Sheppard , H. 2001 . Safety and immunogenicity of a canarypox-vectored HIV type 1 vaccine with or without GP 120 . Journal of Infectious Diseases , 183 : 1343 – 1352 .
  • Buchbinder , S. , Metch , B. , Holte , S.E. , Scheer , S. , Coletti , A. and Vittinghoff , E. 2004 . Determinants of enrollment in a preventive HIV vaccine trial: Hypothetical versus actual willingness and barriers to participation . Journal of Acquired Immune Deficiency Syndromes , 36 : 604 – 612 .
  • Buchbinder , S. , Wheeler , S. , Vittinghoff , E. , McKirnan , D. , Celum , C. , Mayer , K. , et al. ( 2003 ). Declines in risk behaviour are smaller in Phase III vaccine trial participants than in a non-vaccine trial control group . Abstract of paper presented at AIDS Vaccine Conference , New York , September .
  • Chesney , M.A. , Chambers , D.B. and Kahn , J.O. 1997 . Risk behavior for HIV infection in participants in preventive HIV vaccine trials: A cautionary note . Journal of Acquired Immune Deficiency Syndromes , 16 : 266 – 271 .
  • Coletti , A.S. , Heagerty , P. , Sheon , A.R. , Gross , M. , Koblin , B.A. Metzger , D.S. 2003 . Randomised, controlled evaluation of a prototype informed consent process for HIV vaccine efficacy trials . Journal of Acquired Immune Deficiency Syndromes , 32 : 161 – 169 .
  • Dawes , A. , Kafaar , Z. , de Sas Kropiwnicki , Z.O. , Pather , R. and Richter , L. 2004 . Partner violence, attitudes to child discipline and the use of corporal punishment: A South African national survey , Cape Town , , South Africa : Child Youth & Family Development, Human Sciences Research Council .
  • Deacon , H. , Stephney , I. and Prosalendis , S. 2005 . Understanding HIV/AIDS stigma: A theoretical and methodological analysis , 23 Cape Town , , South Africa : HSRC Press .
  • Dunkle , K.L. , Jewkes , R.K. , Brown , H.C. , Gray , G.E. , McIntyre , J.A. and Harlow , S.D. 2004 . Gender-based violence, relationship power, and risk of HIV infection among women attending antenatal clinics in South Africa . Lancet , 363 : 1415 – 1421 .
  • Fuchs , J. , Durham , M. , McLellan-Lemal , E. , Vittinghoff E Buchbinder S & Vax Study Team (2004). Younger HIV vaccine trial participants report negative social impacts [ThPeC7444] . Abstract of paper presented at XV International AIDS Conference, Bangkok, July .
  • Goffman , E. 1963 . Stigma: Notes on the management of a spoiled identity , New York : Simon & Schuster .
  • Grady , C. 1994 . HIV-preventive vaccine research: Selected ethical issues . Journal of Medicine and Philosophy , 19 : 595 – 612 .
  • Gupta , G.R. ( 2005) . Luncheon remarks on women and AIDS . Paper presented at Interactive Forum, Loews L'Enfant Plaza Hotel , June , Washington DC .
  • Harrison , A. , Smit , J.A. and Myer , L. 2000 . Prevention of HIV/AIDS in South Africa: A review of behaviour change interventions, evidence and options for the future . South African Journal of Science , 96 : 285 – 290 .
  • Herek , G.M. 2002 . Thinking about AIDS and stigma: A psychologist's perspective . Journal of Law, Medicine and Ethics , 30 : 594 – 607 .
  • Herek , G.M. and Capitanio , J.P. 1998 . Symbolic prejudice or fear of infection? A functional analysis of AIDS-related stigma . Basic and Applied Social Psychology , 20 : 230 – 241 .
  • Jenkins , R.A. , Thapinta , D. , Morgan , P.A. , Wongkamhaeng , S. , Sornsathapornkul , P. , Bussaratid , V. , et al. , & Thai AIDS Vaccine Evaluation Group ( 2005 ). Behavioural and social issues among volunteers in a preventive HIV vaccine trial in Thailand . Journal of Acquired Immune Deficiency Syndromes , 40 , 592 – 599 .
  • Jenkins , R. , Torugsa , K. , Markowitz , L. , Mason , C. , Jamroentana , V. Brown , A. 2000 . Willingness to participate in HIV-1 vaccine trials among Thai men . Sexually Transmitted Infections , 76 : 386 – 392 .
  • Jermano , J. ( 2000 ). Monitoring of social and behavioral harms in the Phase III trial of AIDS VAX(r) B/B [ThOrD679] . Abstract of paper presented at XIII International AIDS Conference , Durban , August .
  • Jewkes , R. , Levin , J. and Penn-Kekana , L. 2002 . Risk factors for domestic violence: Findings from a South African cross-sectional study . Social Science and Medicine , 55 : 1603 – 1617 .
  • Leider , P.A. 2000 . Domestic AIDS vaccine trials: Addressing the potential for social harm to the subjects of human experiments . California Law Review , 88 : 1185 – 1232 .
  • Link , B.G. and Phelan , J.C. 2001 . Conceptualising stigma . Annual Review of Sociology , 27 : 363 – 385 .
  • MacQueen , K.M. , Buchbinder , S. , Douglas , J.M. , Judson , F.N. , McKirnan , D.J. , & Bartholow , B. ( 1996 ). Required HIV antibody testing, social risk, and HIV-vaccine efficacy trials . AIDS Public Policy Journal , 11 , 104 – 112 .
  • Maduna-Butshe , A.C.Z. 1997 . Women sex workers and the pandemic: Stigma and blame in context . South African AIDS News , 5 : 8 – 11 .
  • Maek-A-Nantawat , W. , Pitisuttithum , P. , Phonrat , B. , Bussaratid , V. , Naksrisook , S. Peonim , W. 2003 . Evaluation of attitude, risk behaviour and expectations among Thai participants in Phase I/II HIV/AIDS vaccine trials . Journal of the Medical Association of Thailand , 86 : 299 – 307 .
  • Melkote , S.R. , Muppidi , S.R. and Goswami , D. 2000 . Social and economic factors in an integrated behavioural and societal approach to communications in HIV/AIDS . Journal of Health Communication , 5 ( Suppl ) : S17 – S27 .
  • Muyinda , H. , Seeley , J. , Pickering , H. and Barton , J. 1997 . Social aspects of AIDS-related stigma in rural Uganda . Health Place , 3 : 143 – 147 .
  • Parker , R. and Aggleton , P. 2003 . HIV and AIDS-related stigma and discrimination: A conceptual framework and implications for action . Social Science and Medicine , 57 : 13 – 24 .
  • Pitisuttithum , P. ( 2000 ). Social harm monitoring among injecting drug users in a Phase III HIV vaccine trial in Bangkok, Thailand: Preliminary results [TuOrD448] . Abstract of paper presented at XIII International AIDS Conference , Durban , August .
  • Pitisuttithum , P. , Martin , M. , & Vanichseni , S. ( 2004 ). Social impact and harm among injecting drug users (IDUs) in a Phase II HIV vaccine trial in Thailand [C11162] . Abstract of paper presented at XV International AIDS Conference , Bangkok , July .
  • Sheon , A. , Wagner , L. , McElrath , M. , Keefer , M. , Zimmerman , E. Israel , H. 1998 . Preventing discrimination against volunteers in prophylactic HIV vaccine trials: Lessons from a Phase II trial . Journal of Acquired Immune Deficiency Syndromes , 19 : 519 – 526 .
  • South African AIDS Vaccine Initiative ( 2002 ). Long-term insurance industry HIV testing protocol—changes to accommodate HIV vaccine trials . Available at: http://www.saavi.org.za/press26sep2002.htm
  • South African Medical Research Council ( 2001 ). Guidelines on ethics for medical research: General principles . Tygerberg , , South Africa : Author .
  • South African Medical Research Council ( 2003 ). Guidelines on ethics for medical research: HIV-preventive vaccine research . Tygerberg , , South Africa : Author .
  • Temoshok , L.R. 1994 . Behavioral research contributions to planning and conducting HIV vaccine efficacy studies . AIDS Research and Human Retroviruses , 10 : S277 – S280 .
  • Thapinta , D. , Jenkins , R.A. , Celentano , D.D. , Nitayaphan , S. , Buapunth , P. Triampon , A. 1999 . Evaluation of behavioral and social issues among Thai HIV vaccine trial volunteers . Journal of Acquired Immune Deficiency Syndromes , 20 : 308 – 315 .
  • UNAIDS ( 2000 ). Ethical Considerations in HIV-preventive Vaccine Research: UNAIDS Guidance Document . Geneva , , Switzerland : UNAIDS .
  • UNAIDS ( 2006 ). Report on the Global AIDS Epidemic . Geneva , , Switzerland : UNAIDS .
  • van Griensven , F. , Vanichseni , S. , Tappero , J. , Pitisuttithum , P. , Kitayaporn , D. , Martin , M. , et al. ( 2003 ). Monitoring of risk behaviour among injection drug users (IDU) in the AIDSVAX B/E vaccine trial in Bangkok: 36 months of follow-up . Abstract of paper presented at AIDS Vaccine Conference , New York , September .
  • Wassenaar , D. , & Barsdorf , N. ( 2007 ). The involvement of women in HIV vaccine trials in Africa . Women and Health , 45 , (in press) .
  • Wassenaar , D. 2005 . WHO-UNAIDS Expert Group (2005). Gender, age and ethnicity in HIV vaccine-related research and clinical trials: Report from a WHO-UNAIDS consultation, 26–28 August 2004, Lausanne, Switzerland . AIDS , 19 : 7 – 28 .
  • WHO-UNAIDS Expert Group (2005) . Gender, age and ethnicity in HIV vaccine-related research and clinical trials: report from a WHO-UNAIDS consultation , 26–28 August 2004. Lausanne, Switzerland. AIDS, 19, W7–W28 .

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