Examining the relationship between psychological distress and adherence to anti-retroviral therapy among Ugandan adolescents living with HIV

References

• Bakanda, C., Birungi, J., Mwesigwa, R., Nachega, J. B., Chan, K., Palmer, A., … Mills, E. J. (2011). Survival of HIV-infected adolescents on antiretroviral therapy in Uganda: Findings from a nationally representative cohort in Uganda. PLoS One, 6(4), e19261. doi:10.1371/journal.pone.0019261
   PubMed Web of Science ®Google Scholar
• Baker, J. V., Peng, G., Rapkin, J., Abrams, D. I., Silverberg, M. J., MacArthur, R. D., … Neaton, J. D. (2008). CD4+ count and risk of non-AIDS diseases following initial treatment for HIV infection. AIDS, 22(7), 841–848. doi: 10.1097/QAD.0b013e3282f7cb76
   PubMed Web of Science ®Google Scholar
• Battles, H. B., & Wiener, L. S. (2002). From adolescence through young adulthood: Psychosocial adjustment associated with long-term survival of HIV. Journal of Adolescent Health, 30(3), 161–168. doi: 10.1016/S1054-139X(01)00341-X
   PubMed Web of Science ®Google Scholar
• Bikaako-Kajura, W., Luyirika, E., Purcell, D. W., Downing, J., Kaharuza, F., Mermin, J., … Bunnell, R. (2006). Disclosure of HIV status and adherence to daily drug regimens among HIV-infected children in Uganda. AIDS and Behavior, 10(1), 85–93. doi: 10.1007/s10461-006-9141-3
   Web of Science ®Google Scholar
• Byakika-Tusiime, J., Crane, J., Oyugi, J. H., Ragland, K., Kawuma, A., Musoke, P., & Bangsberg, D. R. (2009). Longitudinal antiretroviral adherence in HIV+ Ugandan parents and their children initiating HAART in the MTCT-Plus family treatment model: Role of depression in declining adherence over time. AIDS and Behavior, 13(1), 82–91. doi: 10.1007/s10461-009-9546-x
   PubMed Web of Science ®Google Scholar
• Chesney, M., Ickovics, J., Chambers, D., Gifford, A., Neidig, K., Zwickl, B., … Wu, A. (2000). Self-reported adherence to antiretroviral medications among participants in HIV clinical trails: The AATCG adherence instruments. AIDS Care, 12(3), 255–266. doi: 10.1080/09540120050042891
   PubMed Web of Science ®Google Scholar
• Cohen, J. (1992). A power primer. Psychological Bulletin, 112(1), 155–159. doi: 10.1037/0033-2909.112.1.155
   PubMed Web of Science ®Google Scholar
• Cotton, S., Weekes, J. C., McGrady, M. E., Rosenthal, S. L., Michael, S. Y., Pargament, K., … Tsevat, J. (2012). Spirituality and religiosity in urban adolescents with asthma. Journal of Religion and Health, 51(1), 118–131. doi: 10.1007/s10943-010-9408-x
   PubMed Web of Science ®Google Scholar
• Cotton, S., Zebracki, K., Rosenthal, S. L., Tsevat, J., & Drotar, D. (2006). Religion/spirituality and adolescent health outcomes: A review. Journal of Adolescent Health, 38(4), 472–480. doi: 10.1016/j.jadohealth.2005.10.005
   PubMed Web of Science ®Google Scholar
• DiMatteo, M. R., Lepper, H. S., & Croghan, T. W. (2000). Depression is a risk factor for noncompliance with medical treatment: Meta-analysis of the effects of anxiety and depression on patient adherence. Archives of Internal Medicine, 160(14), 2101–2107. doi: 10.1001/archinte.160.14.2101
   PubMed Web of Science ®Google Scholar
• Filmer, D., & Pritchett, L. H. (2001). Estimating wealth effects without expenditure data—or tears: An application to educational enrollments in states of India. Demography, 38(1), 115–132.
   PubMed Web of Science ®Google Scholar
• Fiori, K. L., Brown, E. E., Cortina, K. S., & Antonucci, T. C. (2006). Locus of control as a mediator of the relationship between religiosity and life satisfaction: Age, race, and gender differences. Mental Health, Religion and Culture, 9(03), 239–263. doi: 10.1080/13694670600615482
   Google Scholar
• Fogarty, L., Roter, D., Larson, S., Burke, J., Gillespie, J., & Levy, R. (2002). Patient adherence to HIV medication regimens: A review of published and abstract reports. Patient Education and Counseling, 46(2), 93–108. doi: 10.1016/S0738-3991(01)00219-1
   PubMed Web of Science ®Google Scholar
• Harris, K. M., Halpern, C. T., Whitsel, E., Hussey, J., Tabor, J., Entzel, P., & Udry, J. R. (2009). The national longitudinal study of adolescent health: Research design: Carolina Population Center. Chapel Hill: University of North Carolina at Chapel Hill.
   Google Scholar
• Hood Jr, R. W., Hill, P. C., & Spilka, B. (2009). Psychology of religion: An empirical approach. New York, NY: Guilford Press.
   Google Scholar
• Kapetanovic, S., Wiegand, R. E., Dominguez, K., Blumberg, D., Bohannon, B., Wheeling, J., … the LEGACY Consortium, R. (2011). Associations of medically documented psychiatric diagnoses and risky health behaviors in highly active antiretroviral therapy-experienced perinatally HIV-infected youth. AIDS Patient Care & STDs, 25(8), 493–501. doi: 10.1089/apc.2011.0107
   PubMed Web of Science ®Google Scholar
• Kiboneka, A., Wangisi, J., Nabiryo, C., Tembe, J., Kusemererwa, S., Olupot-Olupot, P., … Montaner, J. S. (2008). Clinical and immunological outcomes of a national paediatric cohort receiving combination antiretroviral therapy in Uganda. Aids, 22(18), 2493–2499. doi: 10.1097/QAD.0b013e328318f148
   PubMed Web of Science ®Google Scholar
• Kudel, I., Cotton, S., Szaflarski, M., Holmes, W. C., & Tsevat, J. (2011). Spirituality and religiosity in patients with HIV: A test and expansion of a model. Annals of Behavioral Medicine, 41(1), 92–103. doi: 10.1007/s12160-010-9229-x
   PubMed Web of Science ®Google Scholar
• Lam, P. K., Naar-King, S., & Wright, K. (2007). Social support and disclosure as predictors of mental health in HIV-positive youth. AIDS Patient Care & STDs, 21(1), 20–29. doi: 10.1089/apc.2006.005
   PubMed Web of Science ®Google Scholar
• Lazarus, R. S., & Folkman, S. (1991). The concept of coping. In A. Monat & R. S. Lazarus (Eds.), Stress and coping: An anthology (3rd ed.) (pp. 189–206). New York, NY: Columbia University Press.
   Google Scholar
• Lima, V. D., Harrigan, R., Bangsberg, D. R., Hogg, R. S., Gross, R., Yip, B., & Montaner, J. S. (2009). The combined effect of modern highly active antiretroviral therapy regimens and adherence on mortality over time. Journal of Acquired Immune Deficiency Syndromes, 50(5), 529–536. doi: 10.1097/QAI.0b013e31819675e9
   PubMed Web of Science ®Google Scholar
• Liu, H., Golin, C. E., Miller, L. G., Hays, R. D., Beck, C. K., Sanandaji, S., … Kaplan, A. H. (2001). A comparison study of multiple measures of adherence to HIV protease inhibitors. Annals of Internal Medicine, 134(10), 968–977. doi: 10.7326/0003-4819-134-10-200105150-00011
   PubMed Web of Science ®Google Scholar
• Lowenthal, E., Lawler, K., Harari, N., Moamogwe, L., Masunge, J., Masedi, M., … Gross, R. (2012). Rapid psychosocial function screening test identified treatment failure in HIV+ African youth. AIDS Care, 24(6), 722–727. doi: 10.1080/09540121.2011.644233
   PubMed Web of Science ®Google Scholar
• MacDonell, K., Naar-King, S., Huszti, H., & Belzer, M. (2013). Barriers to medication adherence in behaviorally and perinatally infected youth living with HIV. AIDS and Behavior, 17(1), 86–93. doi: 10.1007/s10461-012-0364-1
   PubMed Web of Science ®Google Scholar
• Makoae, L. N., Greeff, M., Phetlhu, R. D., Uys, L. R., Naidoo, J. R., Kohi, T. W., … Holzemer, W. L. (2008). Coping with HIV-related stigma in five African countries. Journal of the Association of Nurses in AIDS Care, 19(2), 137–146. doi: 10.1016/j.jana.2007.11.004
   PubMed Web of Science ®Google Scholar
• Measure, DHS. (2012). Uganda demographic and health survey 2011. Calverton, Maryland, USA. Retrieved from http://www.measuredhs.com/pubs/pdf/PR18/PR18.pdf
   Google Scholar
• Mellins, C. A., Kang, E., Leu, C.-S., Havens, J. F., & Chesney, M. A. (2003). Longitudinal study of mental health and psychosocial predictors of medical treatment adherence in mothers living with HIV disease. AIDS Patient Care & STDs, 17(8), 407–416. doi: 10.1089/108729103322277420
   PubMed Web of Science ®Google Scholar
• Menon, A., Glazebrook, C., & Ngoma, M. (2009). Mental health of HIV positive adolescents in Zambia. Medical Journal of Zambia, 36(4), 151–156.
   Google Scholar
• Mills, E. J., Nachega, J. B., Buchan, I., Orbinski, J., Attaran, A., Singh, S., … Thabane, L. (2006). Adherence to antiretroviral therapy in sub-Saharan Africa and North America: A meta-analysis. JAMA: The Journal of the American Medical Association, 296(6), 679–690. doi: 10.1001/jama.296.6.679
   PubMed Web of Science ®Google Scholar
• Mukolo, A., & Wallston, K. A. (2012). The relationship between positive psychological attributes and psychological well-being in persons with HIV/AIDS. AIDS and Behavior, 16(8), 2374–2381. doi: 10.1007/s10461-011-0029-5
   PubMed Web of Science ®Google Scholar
• Murphy, D. A., Belzer, M., Durako, S. J., Sarr, M., Wilson, C. M., & Muenz, L. R. (2005). Longitudinal antiretroviral adherence among adolescents infected with human immunodeficiency virus. Archives of Pediatrics & Adolescent Medicine, 159(8), 764–770. doi: 10.1001/archpedi.159.8.764
   PubMed Web of Science ®Google Scholar
• Murphy, D. A., Moscicki, A. B., Vermund, S. H., & Muenz, L. R. (2000). Psychological distress among HIV+ adolescents in the REACH study: Effects of life stress, social support, and coping. Journal of Adolescent Health, 27(6), 391–398. doi: 10.1016/S1054-139X(00)00158-0
   PubMed Web of Science ®Google Scholar
• Murphy, D. A., Wilson, C., Durako, S., Muenz, L., & Belzer, M. (2001). Antiretroviral medication adherence among the REACH HIV-infected adolescent cohort in the USA. AIDS Care, 13(1), 27–40. doi: 10.1080/09540120020018161
   PubMed Web of Science ®Google Scholar
• Musiime, V., Kaudha, E., Kayiwa, J., Mirembe, G., Odera, M., Kizito, H., … Colebunders, R. (2013). Antiretroviral drug resistance profiles and response to second-line therapy among HIV type 1-infected Ugandan children. AIDS Research and Human Retroviruses, 29(3), 449–455. doi: 10.1089/aid.2012.0283
   PubMed Web of Science ®Google Scholar
• Musisi, S., & Kinyanda, E. (2003). Psychological problems of HIV sero-positive adolescents as seen at Mildmay Center, Kampala. Proceeds of The Eastern African Regional Psychiatric Annual Conference, Nairobi, Kenya.
   Google Scholar
• Musisi, S., & Kinyanda, E. (2009). Emotional and behavioural disorders in HIV seropositive adolescents in urban Uganda. East African Medical Journal, 86(1), 16–24. doi: 10.4314/eamj.v86i1.46923
   PubMedGoogle Scholar
• Mutumba, M., Resnicow, K., Bauermeister, J. A., Harper, G., Musiime, V., Snow, R., & Lepkowski, J. M. (2015). Development of a psychosocial distress measure for Ugandan adolescents living with HIV. AIDS and Behavior, 19(2), 380–392. doi: 10.1007/s10461-014-0973-y
   PubMed Web of Science ®Google Scholar
• Naar-King, S., Templin, T., Wright, K., Frey, M., Parsons, J. T., & Lam, P. (2006). Psychosocial factors and medication adherence in HIV-positive youth. AIDS Patient Care & STDs, 20(1), 44–47. doi: 10.1089/apc.2006.20.44
   PubMed Web of Science ®Google Scholar
• Nabukeera-Barungi, N., Kalyesubula, I., Kekitiinwa, A., Byakika-Tusiime, J., & Musoke, P. (2007). Adherence to antiretroviral therapy in children attending Mulago Hospital, Kampala. Annals of Tropical Paediatrics: International Child Health, 27(2), 123–131. doi: 10.1179/146532807X192499
   PubMed Web of Science ®Google Scholar
• Nachega, J. B., Marconi, V. C., van Zyl, G. U., Gardner, E. M., Preiser, W., … Gross, R. (2011). HIV treatment adherence, drug resistance, virologic failure: Evolving concepts. Infectious Disorders-Drug Targets, 11(2), 167–174. doi: 10.2174/187152611795589663
   PubMedGoogle Scholar
• Nugent, N. R., Brown, L. K., Belzer, M., Harper, G. W., Nachman, S., & Naar-King, S. (2010). Youth living with HIV and problem substance use: Elevated distress is associated with nonadherence and sexual risk. Journal of the International Association of Physicians in AIDS Care (JIAPAC), 9(2), 113–115. doi: 10.1177/1545109709357472
   PubMedGoogle Scholar
• Otolok-Tanga, E., Atuyambe, L., Murphey, C., Ringheim, K. E., & Woldehanna, S. (2007). Examining the actions of faith-based organizations and their influence on HIV/AIDS-related stigma: A case study of Uganda. Journal of African Health Sciences, 7(1), 55–60.
   PubMedGoogle Scholar
• Pargament, K., Feuille, M., & Burdzy, D. (2011). The brief RCOPE: Current psychometric status of a short measure of religious coping. Religions, 2(1), 51–76. doi: 10.3390/rel2010051
   Web of Science ®Google Scholar
• Pargament, K., McCarthy, S., Shah, P., Ano, G., Tarakeshwar, N., Wachholtz, A., … Locher, A. (2004). Religion and HIV: A review of the literature and clinical implications. Southern Medical Journal, 97(12), 1201–1209. doi: 10.1097/01.SMJ.0000146508.14898.E2
   PubMed Web of Science ®Google Scholar
• Paterson, D. L., Swindells, S., Mohr, J., Brester, M., Vergis, E. N., Squier, C., … Singh, N. (2000). Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Annals of Internal Medicine, 133(1), 21–30. doi: 10.7326/0003-4819-133-1-200007040-00004
   PubMed Web of Science ®Google Scholar
• Patterson, J. M., & McCubbin, H. I. (1987). Adolescent coping style and behaviors: Conceptualization and measurement. Journal of Adolescence, 10(2), 163–186. doi: 10.1016/S0140-1971(87)80086-6
   PubMed Web of Science ®Google Scholar
• Prado, G., Feaster, D. J., Schwartz, S. J., Pratt, I. A., Smith, L., & Szapocznik, J. (2004). Religious involvement, coping, social support, and psychological distress in HIV-seropositive African American mothers. AIDS and Behavior, 8(3), 221–235. doi: 10.1023/B:AIBE.0000044071.27130.46
   PubMed Web of Science ®Google Scholar
• Reisner, M. S. L., Mimiaga, M. J., Skeer, M. M., Perkovich, M. B., Johnson, M. C. V., & Safren, S. A. (2009). A review of HIV antiretroviral adherence and intervention studies among HIV-infected youth. Topics in HIV Medicine: A Publication of the International AIDS Society, 17(1), 14–25.
   PubMedGoogle Scholar
• Sarason, I. G., Sarason, B. R., Shearin, E. N., & Pierce, G. R. (1987). A brief measure of social support: Practical and theoretical implications. Journal of Social and Personal Relationships, 4(4), 497–510. doi: 10.1177/0265407587044007
   Web of Science ®Google Scholar
• Schapman, A. M., & Inderbitzen-Nolan, H. M. (2002). The role of religious behaviour in adolescent depressive and anxious symptomatology. Journal of Adolescence, 25(6), 631–643. doi: 10.1006/jado.2002.0510
   PubMed Web of Science ®Google Scholar
• Sebunya, R., Musiime, V., Kitaka, S. B., & Ndeezi, G. (2013). Incidence and risk factors for first line anti retroviral treatment failure among Ugandan children attending an urban HIV clinic. AIDS Research and Therapy, 10(1), 25. doi:10.1186/1742-6405-10-25
   PubMed Web of Science ®Google Scholar
• Skinner, E. A. (1995). Perceived control, motivation, & coping (Vol. 8). Thousand Oaks, CA: Sage.
   Google Scholar
• Szaflarski, M. (2013). Spirituality and religion among HIV-infected individuals. Current HIV/AIDS Reports, 10(4), 324–332. doi: 10.1007/s11904-013-0175-7
   PubMed Web of Science ®Google Scholar
• UNAIDS. (2014). Global report: UNAIDS report on the global AIDS epidemic 2013. Geneva. Retrieved from http://www.unaids.org/en/resources/campaigns/globalreport2013/globalreport/
   Google Scholar
• UNICEF. (2014). Countdown to zero: Elimination of new HIV infections among children by 2015 and keeping their mothers alive. Geneva. Retrieved from http://www.unicef.org/french/aids/files/hiv_pmtctfactsheetUganda.pdf
   Google Scholar
• Uthman, O. A., Magidson, J. F., Safren, S. A., & Nachega, J. B. (2014). Depression and adherence to antiretroviral therapy in low-, middle-and high-income countries: A systematic review and meta-analysis. Current HIV/AIDS Reports, 11(3), 291–307. doi: 10.1007/s11904-014-0220-1
   PubMed Web of Science ®Google Scholar
• Varas-Díaz, N., Neilands, T., Malavé Rivera, S., & Betancourt, E. (2010). Religion and HIV/AIDS stigma: Implications for health professionals in Puerto Rico. Global Public Health, 5(3), 295–312. doi: 10.1080/17441690903436581
   PubMed Web of Science ®Google Scholar
• Vreeman, R. C., Wiehe, S. E., Pearce, E. C., & Nyandiko, W. M. (2008). A systematic review of pediatric adherence to antiretroviral therapy in low-and middle-income countries. The Pediatric Infectious Disease Journal, 27(8), 686–691. doi: 10.1097/INF.0b013e31816dd325
   PubMed Web of Science ®Google Scholar
• Wagner, G. J. (2002). Predictors of antiretroviral adherence as measured by self-report, electronic monitoring, and medication diaries. AIDS Patient Care & STDs, 16(12), 599–608. doi: 10.1089/108729102761882134
   PubMed Web of Science ®Google Scholar
• Wiens, M. O., MacLeod, S., Musiime, V., Ssenyonga, M., Kizza, R., Bakeera-Kitaka, S., … Ssali, F. (2012). Adherence to antiretroviral therapy in HIV-positive adolescents in Uganda assessed by multiple methods. Pediatric Drugs, 14(5), 331–335. doi: 10.1007/BF03262238
   PubMed Web of Science ®Google Scholar
• Williams, P. L., Storm, D., Montepiedra, G., Nichols, S., Kammerer, B., Sirois, P. A., … Malee, K. (2006). Predictors of adherence to antiretroviral medications in children and adolescents with HIV infection. Pediatrics, 118(6), e1745–e1757. doi: 10.1542/peds.2006-0493
   PubMed Web of Science ®Google Scholar