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AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 31, 2019 - Issue 8
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Articles

Social support, stigma, and the mediating roles of depression on self-reported medication adherence of HAART recipients in China

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Pages 942-950 | Received 02 Jul 2018, Accepted 07 Feb 2019, Published online: 04 Mar 2019

References

  • Aibibula, W., Cox, J., Hamelin, A. M., Moodie, E. E. M., Naimi, A. I., McLinden, T. … Brassard, P. (2017). Impact of food insecurity on depressive symptoms among HIV-HCV co-infected people. AIDS and Behavior, 21(12), 3464–3472. doi: 10.1097/qai.000000000000154310.1007/s10461-017-1942-z
  • Alonzo, A. A., & Reynolds, N. R. (1995). Stigma, HIV and AIDS: An exploration and elaboration of a stigma trajectory. Social Science & Medicine, 41(3), 303–315. doi: 10.1016/0277-9536(94)00384-6
  • Ammassari, A., Antinori, A., Aloisi, M. S., Trotta, M. P., Murri, R., Bartoli, L., … Starace, F. (2004). Depressive symptoms, neurocognitive impairment, and adherence to highly active antiretroviral therapy among HIV-infected persons. Psychosomatics, 45(5), 394–402. doi: 10.1176/appi.psy.45.5.394
  • Anuradha, S., Joshi, A., Negi, M., Nischal, N., Rajeshwari, K., & Dewan, R. (2013). Factors influencing adherence to ART: New insights from a center providing free ART under the national program in Delhi, India. Journal of the International Association of Providers of AIDS Care (JIAPAC), 12(3), 195–201. doi: 10.1177/1545109711431344
  • Babson, K. A., Heinz, A. J., & Bonnmiller, M. O. (2013). Hiv medication adherence and HIV symptom severity: The roles of sleep quality and memory. Aids Patient Care & Stds, 27(10), 544–552. doi: 10.1089/apc.2013.0221
  • Berger, B. E., Ferrans, C. E., & Lashley, F. R. (2001). Measuring stigma in people with HIV: Psychometric assessment of the HIV stigma scale. Research in Nursing & Health, 24(6), 518–529. doi: 10.1002/nur.10011
  • Casale, M. (2015). The importance of family and community support for the health of HIV-affected populations in Southern Africa: What do we know and where to from here? British Journal of Health Psychology, 20(1), 21–35. doi: 10.1111/bjhp.12127
  • Cha, E. S., Erlen, J. A., Kim, K. H., Sereika, S. M., & Caruthers, D. (2008). Mediating roles of medication–taking self-efficacy and depressive symptoms on self-reported medication adherence in persons with HIV: A questionnaire survey. International Journal of Nursing Studies, 45(8), 1175–1184. doi: 10.1016/j.ijnurstu.2007.08.003
  • Chesney, M. A., Ickovics, J. R., Chambers, D. B., Gifford, A. L., Neidig, J., Zwickl, B., & Wu, A. W. (2000). Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: The AACTG adherence instruments. Patient care committee & adherence working group of the outcomes committee of the Adult AIDS Clinical Trials Group (AACTG). AIDS Care, 12(3), 255–266. doi: 10.1080/09540120050042891
  • Cohen, M. A., Alfonso, C. A., Hoffman, R. G., Milau, V., & Carrera, G. (2001). The impact of PTSD on treatment adherence in persons with HIV infection. General Hospital Psychiatry, 23(5), 294–296. doi: 10.1016/S0163-8343(01)00152-9
  • Contardo, C., Black, A. C., Beauvais, J., Dieckhaus, K., & Rosen, M. I. (2009). Relationship of prospective memory to neuropsychological function and antiretroviral adherence. Archives of Clinical Neuropsychology the Official Journal of the National Academy of Neuropsychologists, 24(6), 547–554. doi: 10.1093/arclin/acp046
  • Diiorio, C., Mccarty, F., Depadilla, L., Resnicow, K., Holstad, M. D., Yeager, K., … Lundberg, B. (2009). Adherence to antiretroviral medication regimens: A test of a psychosocial model. Aids & Behavior, 13(1), 10–22. doi: 10.1007/s10461-007-9318-4
  • Doku, P. N., Dotse, J. E., & Mensah, K. A. (2015). Perceived social support disparities among children affected by HIV/AIDS in Ghana: A cross-sectional survey. BMC Public Health, 15(1), 538. doi: 10.1186/s12889-015-1856-5
  • Farber, E. W., Lamis, D. A., Shahane, A. A., & Campos, P. E. (2014). Personal meaning, social support, and perceived stigma in individuals receiving HIV mental health services. Journal of Clinical Psychology in Medical Settings, 21(2), 173–182. doi: 10.1007/s10880-014-9394-3
  • Galvan, F. H., Davis, E. M., Banks, D., & Bing, E. G. (2008). Hiv stigma and social support among African Americans. Aids Patient Care & Stds, 22(5), 423–436. doi: 10.1089/apc.2007.0169
  • Gebo, K. A., Keruly, J., & Moore, R. D. (2003). Association of social stress, illicit drug use, and health beliefs with nonadherence to antiretroviral therapy. Journal of General Internal Medicine, 18(2), 104–111. doi: 10.1046/j.1525-1497.2003.10801.x
  • Godin, G., Cote, J., Naccache, H., Lambert, L. D., & Trottier, S. (2005). Prediction of adherence to antiretroviral therapy: A one-year longitudinal study. AIDS Care, 17(4), 493–504. doi: 10.1080/09540120412331291715
  • Goffman, E. (1963). Stigma: Notes on the management of spoiled identity.
  • Harries, A. D., Gomani, P., Teck, R., de Teck, O. A., Bakali, E., Zachariah, R., … Mpazanje, R. (2004). Monitoring the response to antiretroviral therapy in resource-poor settings: The Malawi model. Transactions of the Royal Society of Tropical Medicine and Hygiene, 98(12), 695–701. doi: 10.1016/j.trstmh.2004.05.002
  • Henderson, K. C., Hindman, J., Johnson, S. C., Valuck, R. J., & Kiser, J. J. (2011). Assessing the effectiveness of pharmacy-based adherence interventions on antiretroviral adherence in persons with HIV. AIDS Patient Care and STDs, 25(4), 221–228. doi: 10.1089/apc.2010.0324
  • Hu, L. T., & Bentler, P. M. (1999). Cutoff criteria for fit indexes in covariance structure anaysis: Conventional criteria versus new alternatives. Structural Equation Modeling, 6(1), 1–55. doi: 10.1080/10705519909540118
  • Janice Yanushka, B., Solomon, S. E., Carol, M., & Rex, F. (2007). Measurement of stigma in people with HIV: A reexamination of the HIV stigma scale. Aids Education & Prevention Official Publication of the International Society for Aids Education, 19(3), 198–208. doi: 10.1521/aeap.2007.19.3.198
  • Katz, I. T., Ryu, A. E., Onuegbu, A. G., Psaros, C., Weiser, S. D., Bangsberg, D. R., & Tsai, A. C. (2013). Impact of HIV-related stigma on treatment adherence: Systematic review and meta-synthesis. Journal of the International AIDS Society, 16(Supplement 3S2), 18640. doi: 10.7448/IAS.16.3.18640
  • Kekwaletswe, C. T., Jordaan, E., Nkosi, S., & Morojele, N. K. (2017). Social support and the mediating roles of alcohol use and adherence self-efficacy on Antiretroviral Therapy (ART) adherence among ART recipients in Gauteng, South Africa. AIDS and Behavior, 21(7), 1846–1856. doi: 10.1007/s10461-016-1595-3
  • Kleeberger, C. A., Buechner, J., Palella, F., Detels, R., Riddler, S., Godfrey, R., & Jacobson, L. P. (2004). Changes in adherence to highly active antiretroviral therapy medications in the multicenter AIDS cohort study. Aids (london, England), 18(4), 683–688. doi: 10.1097/00002030-200403050-00013
  • Kline, R. B. (2005). Principles and practice of structural equation modeling. New York: Guilford Press.
  • Li, J., Li, J., Thornicroft, G., Yang, H., Chen, W., & Huang, Y. (2015). Training community mental health staff in Guangzhou, China: Evaluation of the effect of a new training model. BMC Psychiatry, 15(263), doi: 10.1186/s12888-015-0660-1
  • Li, J., Mo, P. K., Wu, A. M., & Lau, J. T. (2017). Roles of self-stigma, social support, and positive and negative affects as determinants of depressive symptoms among HIV infected men who have sex with men in China. AIDS and Behavior, 21(1), 261–273. doi: 10.1007/s10461-016-1321-1
  • Lin, S. H., & Hsieh, P. J. (2010). Book Review: Kline, R. B. (2005). Principles and practice of structural equation modeling (2nd ed.). New York: Guilford. 366 pp., $40.50 paperback, ISBN 978-1-57230-690-5. Research on Social Work Practice, 20(1), 126–128. doi: 10.1177/1049731509336986
  • Logie, C., James, L., Tharao, W., & Loutfy, M. (2013). Associations between HIV-related stigma, racial discrimination, gender discrimination, and depression among HIV-positive African, Caribbean, and Black women in Ontario, Canada. AIDS Patient Care and STDs, 27(2), 114–122. doi: 10.1089/apc.2012.0296
  • Maccallum, R. C., & Austin, J. T. (2000). Applications of structural equation modeling in psychological research. Annual Review of Psychology, 51(1), 201–226. doi: 10.1146/annurev.psych.51.1.201
  • McIntosh, R. C., Ironson, G., Antoni, M., Fletcher, M. A., & Schneiderman, N. (2016). Alexithymia, assertiveness and psychosocial functioning in HIV: Implications for medication adherence and disease severity. AIDS and Behavior, 20(2), 325–338. doi: 10.1007/s10461-015-1126-7
  • Meng, Y. J., Li, N. X., Liu, C. J., Chen, J. H., Song, Y. C., & Qian, Z. S. (2008). Quality of life and hostile mentality trend of patients with HIV/AIDS in China. Public Health, 122(4), 404–411. doi: 10.1016/j.puhe.2007.06.007
  • Mental health in China: what will be achieved by 2020? (2015). Lancet, 385(9987), 2548. doi: 10.1016/s0140-6736(15)61146-1
  • Mo, P. K., Lau, J. T., Yu, X., & Gu, J. (2015). A model of associative stigma on depression and anxiety among children of HIV-infected parents in China. AIDS and Behavior, 19(1), 50–59. doi: 10.1007/s10461-014-0809-9
  • Musumari, P. M., Wouters, E., Kayembe, P. K., Kiumbu, N. M., Mbikayi, S. M., Suguimoto, S. P., … Piot, P. (2014). Food insecurity is associated with increased risk of non-adherence to antiretroviral therapy among HIV-infected adults in the Democratic Republic of Congo: A cross-sectional study. PLoS One, 9(1), e85327. doi: 10.1371/journal.pone.0085327
  • Okeke, B. O. (2016). Social support seeking and self-efficacy-building strategies in enhancing the emotional well-being of informal HIV/AIDS caregivers in Ibadan, Oyo state, Nigeria. SAHARA-J: Journal of Social Aspects of HIV/AIDS, 13(1), 35–40. doi: 10.1080/17290376.2015.1126794
  • Onyebuchi-Iwudibia, O., & Brown, A. (2014). Hiv and depression in Eastern Nigeria: The role of HIV-related stigma. AIDS Care, 26(5), 653–657. doi: 10.1080/09540121.2013.844761
  • Osman, A., Lamis, D. A., Freedenthal, S., Gutierrez, P. M., & Mcnaughton-Cassill, M. (2014). The Multidimensional scale of perceived social support: Analyses of internal reliability, measurement invariance, and correlates across gender. Journal of Personality Assessment, 96(1), 103–112. doi: 10.1080/00223891.2013.838170
  • Ostrop, N. J., & Gill, M. J. (2000). Antiretroviral medication adherence and persistence with respect to adherence tool usage. AIDS Patient Care and STDs, 14(7), 351–358. doi: 10.1089/108729100413220
  • Paterson, D. L., Swindells, S., Mohr, J., Brester, M., Vergis, E. N., Squier, C. … Singh, N. (2000). Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Annals of Internal Medicine, 133(1), 21–30. doi: 10.7326/0003-4819-133-1-200007040-00004
  • Pichon, L. C., Rossi, K. R., Ogg, S. A., Krull, L. J., & Griffin, D. Y. (2015). Social support, stigma and disclosure: Examining the relationship with HIV medication adherence among Ryan White program clients in the Mid-South USA. International Journal of Environmental Research and Public Health, 12(6), 7073–7084. doi: 10.3390/ijerph120607073
  • Prachakul, W., Grant, J. S., & Keltner, N. L. (2007). Relationships among functional social support, HIV-related stigma, social problem solving, and depressive symptoms in people living with HIV: A pilot study. . Journal of the Association of Nurses in Aids Care, 18(6), 67–76. doi: 10.1016/j.jana.2007.08.002
  • Rao, D., Chen, W. T., Pearson, C. R., Simoni, J. M., Fredriksen-Goldsen, K., Nelson, K., … Zhang, F. (2012). Social support mediates the relationship between HIV stigma and depression/quality of life among people living with HIV in Beijing, China. International Journal of STD & AIDS, 23(7), 481–484. doi: 10.1258/ijsa.2009.009428
  • Reisner, S. L., Mimiaga, M. J., Skeer, M., Perkovich, B., Johnson, C. V., & Safren, S. A. (2009). A review of HIV antiretroviral adherence and intervention studies among HIV–infected youth. Topics in Hiv Medicine A Publication of the International Aids Society Usa, 17(1), 14.
  • Safren, S. A., & Gershuny, B. E. (2003). Symptoms of posttraumatic stress and death anxiety in persons with HIV and medication adherence difficulties. Aids Patient Care & Stds, 17(12), 657–664. doi: 10.1089/108729103771928717
  • Saha, R., Saha, I., Sarkar, A. P., Das, D. K., Misra, R., Bhattacharya, K., … Bhattacharya, A. (2014). Adherence to highly active antiretroviral therapy in a tertiary care hospital in West Bengal, India. Singapore Medical Journal, 55(2), 92–98. doi: 10.11622/smedj.2014021
  • Schönnesson, L. N., Williams, M. L., Ross, M. W., Bratt, G., & Keel, B. (2007). Factors associated with suboptimal antiretroviral therapy adherence to dose, schedule, and dietary instructions. Aids & Behavior, 11(2), 175–183. doi: 10.1007/s10461-006-9160-0
  • Senter, H. F. (2008). Applied linear statistical models (Vol. 103).
  • Shively, M., Smith, T. L., Bormann, J., & Gifford, A. L. (2002). Evaluating self-efficacy for HIV disease management skills. Aids & Behavior, 6(4), 371–379. doi: 10.1023/A:1021156914683
  • Shrout, P. E., & Bolger, N. (2002). Mediation in experimental and nonexperimental studies: New procedures and recommendations. Psychological Methods, 7(4), 422–445. doi: 10.1037/1082-989X.7.4.422
  • Sledjeski, E. M., Delahanty, D. L., & Bogart, L. M. (2005). Incidence and impact of posttraumatic stress disorder and comorbid depression on adherence to HAART and CD4+ counts in people living with HIV. Aids Patient Care & Stds, 19(11), 728–736. doi: 10.1089/apc.2005.19.728
  • Stutterheim, S. E., Bos, A. E., Pryor, J. B., Brands, R., Liebregts, M., & Schaalma, H. P. (2011). Psychological and social correlates of HIV status disclosure: The significance of stigma visibility. AIDS Education and Prevention, 23(4), 382–392. doi: 10.1521/aeap.2011.23.4.382
  • Sun, L., Yang, S. M., Wu, H., Chen, B., Wang, C. J., & Li, X. F. (2017). Reliability and validity of the Chinese version of the HIV treatment adherence self-efficacy scale in mainland China. International Journal of STD & AIDS, 28(8), 829–837. doi: 10.1177/0956462416673922
  • Takada, S., Weiser, S. D., Kumbakumba, E., Muzoora, C., Martin, J. N., Hunt, P. W., … Tsai, A. C. (2014). The dynamic relationship between social support and HIV-related stigma in rural Uganda. Annals of Behavioral Medicine, 48(1), 26–37. doi: 10.1007/s12160-013-9576-5
  • Tesfaw, G., Ayano, G., Awoke, T., Assefa, D., Birhanu, Z., Miheretie, G., & Abebe, G. (2016). Prevalence and correlates of depression and anxiety among patients with HIV on-follow up at alert hospital, Addis Ababa, Ethiopia. BMC Psychiatry, 16(1), 368. doi: 10.1186/s12888-016-1037-9
  • Tse, S., Ran, M. S., Huang, Y., & Zhu, S. (2013). Mental health care reforms in Asia: The urgency of now: Building a recovery-oriented, community mental health service in China. Psychiatric Services, 64(7), 613–616. doi: 10.1176/appi.ps.000022013
  • Varni, S. E., Miller, C. T., Mccuin, T., & Solomon, S. E. (2012). Disengagement and engagement coping with HIV/AIDS stigma and psychological well-being of people with HIV/AIDS. Journal of Social and Clinical Psychology, 31(2), 123–150. doi: 10.1521/jscp.2012.31.2.123
  • Vyavaharkar, M., Moneyham, L., Corwin, S., Saunders, R., Annang, L., & Tavakoli, A. (2010). Relationships between stigma, social support, and depression in HIV-infected African American women living in the rural Southeastern United States. Journal of the Association of Nurses in AIDS Care, 21(2), 144–152. doi: 10.1016/j.jana.2009.07.008
  • Wagner, G. J., Linnemayr, S., Ghosh-Dastidar, B., Currier, J. S., Hoffman, R., & Schneider, S. (2016). Supporting treatment adherence readiness through training (START) for patients with HIV on antiretroviral therapy: Study protocol for a randomized controlled trial. Trials, 17(162), 162. doi: 10.1186/s13063-016-1287-3
  • Waite, K. R., Paasche-Orlow, M., Rintamaki, L. S., Davis, T. C., & Wolf, M. S. (2008). Literacy, social stigma, and HIV medication adherence. Journal of General Internal Medicine, 23(9), 1367–1372. doi: 10.1007/s11606-008-0662-5
  • Waldropvalverde, D., Ownby, R. L., Wilkie, F. L., Mack, A., Kumar, M., & Metsch, L. (2006). Neurocognitive aspects of medication adherence in HIV-positive injecting drug users. Aids & Behavior, 10(3), 287–297. doi: 10.1007/s10461-005-9062-6
  • Walsh, J. C., Mandalia, S., & Gazzard, B. G. (2002). Responses to a 1 month self-report on adherence to antiretroviral therapy are consistent with electronic data and virological treatment outcome. Aids (london, England), 16(2), 269–277. doi: 10.1097/00002030-200201250-00017
  • Wellman, B., & Wortley, S. (1990). Different strokes from different folks: Community ties and social support. American Journal of Sociology, 96(3), 558–588. doi: 10.1086/229572
  • White, W., Grant, J. S., Pryor, E. R., Keltner, N. L., Vance, D. E., & Raper, J. L. (2012). Do social support, stigma, and social problem-solving skills predict depressive symptoms in people living with HIV? A mediation analysis. Research and Theory for Nursing Practice, 26(3), 182–204. doi: 10.1891/1541-6577.26.3.182
  • Wohl, A. R., Galvan, F. H., Carlos, J. A., Myers, H. F., Garland, W., Witt, M. D., … George, S. (2013). A comparison of MSM stigma, HIV stigma and depression in HIV-positive Latino and African American men who have sex with men (MSM). AIDS and Behavior, 17(4), 1454–1464. doi: 10.1007/s10461-012-0385-9
  • Yang, C., Nay, S., & Hoyle, R. H. (2010). Three approaches to using lengthy ordinal scales in structural equation models: Parceling, latent scoring, and shortening scales. Applied Psychological Measurement, 34(2), 122. doi: 10.1177/0146621609338592
  • Zeng, C., Li, L., Hong, Y. A., Zhang, H., Babbitt, A. W., Liu, C. … Guo, Y. (2018). A structural equation model of perceived and internalized stigma, depression, and suicidal status among people living with HIV/AIDS. BMC Public Health, 18(1), 138. doi: 10.1186/s12889-018-5053-1

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