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AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 31, 2019 - Issue 10
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Articles

HIV pre-exposure prophylaxis (PrEP) awareness and acceptability among trans women: a review

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Pages 1234-1240 | Received 24 Sep 2018, Accepted 16 Apr 2019, Published online: 01 May 2019

References

  • Baeten, J. M., Donnell, D., Ndase, P., Mugo, N. R., Campbell, J. D., Wangisi, J., … Celum, C. (2012). Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. The New England Journal of Medicine, 367(5), 399–410. doi: 10.1056/NEJMoa1108524
  • Baral, S. D., Poteat, T., Strömdahl, S., Wirtz, A. L., Guadamuz, T. E., & Beyrer, C. (2013). Worldwide burden of HIV in transgender women: a systematic review and meta-analysis. The Lancet Infectious Diseases, 13(3), 214–222. doi: 10.1016/S1473-3099(12)70315-8
  • Bockting, W. O. (1999). From construction to context: Gender through the eyes of the transgendered. SIECUS Report, 28(1), 3–7.
  • Brennan, J., Kuhns, L. M., Johnson, A. K., Belzer, M., Wilson, E. C., & Garofalo, R. (2012). Syndemic theory and HIV-related risk among young transgender women: The role of multiple, co-occurring health problems and social marginalization. American Journal of Public Health, 102(9), 1751–1757. doi: 10.2105/AJPH.2011.300433
  • Choopanya, K., Martin, M., Suntharasamai, P., Sangkum, U., Mock, P. A., Leethochawalit, M., … Vanichseni, S. (2013). Antiretroviral prophylaxis for HIV infection in injecting drug users in Bangkok, Thailand (the Bangkok Tenofovir study): a randomised, double-blind, placebo-controlled phase 3 trial. The Lancet, 381(9883), 2083–2090. doi: 10.1016/S0140-6736(13)61127-7
  • Coleman, E., Bockting, W., Botzer, M., Cohen-Kettenis, G., DeCuypere, G., Feldman, J., … Zucker, K. (2012). Standards of care for the health of transsexual, transgender, and gender-Nonconforming people, version 7. International Journal of Transgenderism, 13(4), 165–232. doi: 10.1080/15532739.2011.700873
  • Deutsch, M. B., Glidden, D. V., Sevelius, J., Keatley, J., McMahan, V., Guanira, J., … Grant, R. M. (2015). HIV pre-exposure prophylaxis in transgender women: A subgroup analysis of the iPrEx trial. The Lancet HIV, 2(12), e512–e519. doi: 10.1016/S2352-3018(15)00206-4
  • Draper, B. L., Fowkes, F. J. I., Oo, Z. M., Thein, Z. W., Aung, P. P., Veronese, V., … Stoové, M. (2017). Willingness to use HIV pre-exposure prophylaxis among gay men, other men who have sex with men and transgender women in Myanmar. Journal of the International AIDS Society, 20(1), 21885. doi: 10.7448/IAS.20.1.21885
  • Eaton, L. A., Kalichman, S. C., Price, D., Finneran, S., Allen, A., & Maksut, J. (2017a). Stigma and conspiracy beliefs related to pre-exposure prophylaxis (PrEP) and interest in using PrEP among black and white men and transgender women who have sex with men. AIDS and Behavior, 21(5), 1236–1246. doi: 10.1007/s10461-017-1690-0
  • Eaton, L. A., Matthews, D. D., Driffin, D. D., Bukowski, L., Wilson, P. A., & Stall, R. D. (2017b). A multi-US city assessment of awareness and uptake of pre-exposure prophylaxis (PrEP) for HIV prevention among black men and transgender women who have sex with men. Prevention Science, 18(5), 505–516. doi: 10.1007/s11121-017-0756-6
  • Escudero, D. J., Kerr, T., Operario, D., Socías, M. E., Sued, O., & Marshall, B. D. L. (2015). Inclusion of trans women in pre-exposure prophylaxis trials: A review. AIDS Care, 27(5), 637–641. doi: 10.1080/09540121.2014.986051
  • Fiereck, K. (2015). Cultural conundrums: The ethics of epidemiology and the problems of population in implementing pre-exposure prophylaxis. Developing World Bioethics, 15(1), 27–39. doi: 10.1111/dewb.12034
  • Fonner, V. A., Dalglish, S. L., Kennedy, C. E., Baggaley, R., O'Reilly, K. R., Koechlin, F. M., … Grant, R. M. (2016). Effectiveness and safety of oral HIV preexposure prophylaxis for all populations. Aids (london, England), 30(12), 1973–1983. doi: 10.1097/QAD.0000000000001145
  • Garnett, M., Hirsch-Moverman, Y., Franks, J., Hayes-Larson, E., El-Sadr, W. M., & Manheimer, S. (2018). Limited awareness of pre-exposure prophylaxis among black men who have sex with men and transgender women in New York city. AIDS Care, 30(1), 9–17. doi: 10.1080/09540121.2017.1363364
  • Golub, S. A. (2018). PrEP stigma: Implicit and explicit drivers of disparity. Current HIV/AIDS Reports, 15(2), 190–197. doi: 10.1007/s11904-018-0385-0
  • Grant, R. M., Anderson, P. L., McMahan, V., Liu, A., Amico, K. R., Mehrotra, M., … Glidden, D. V. (2014). Uptake of pre-exposure prophylaxis, sexual practices, and HIV incidence in men and transgender women who have sex with men: A cohort study. The Lancet Infectious Diseases, 14(9), 820–829. doi: 10.1016/S1473-3099(14)70847-3
  • Grant, R. M., Lama, J. R., Anderson, P. L., McMahan, V., Liu, A. Y., Vargas, L., … Glidden, D. V. (2010). Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. The New England Journal of Medicine, 363(27), 2587–2599. doi: 10.1056/NEJMoa1011205
  • Grant, R. M., Sevelius, J. M., Guanira, J. V., Aguilar, J. V., Chariyalertsak, S., & Deutsch, M. B. (2016). Transgender women in clinical trials of pre-exposure prophylaxis. Journal of Acquired Immune Deficiency Syndromes, 72(Suppl.3), S226–S229. doi: 10.1097/QAI.0000000000001090
  • Grinsztejn, B., Hoagland, B., Moreira, R. I., Kallas, E. G., Madruga, J. V., Goulart, S., … Veloso, V. G. (2018). Retention, engagement, and adherence to pre-exposure prophylaxis for men who have sex with men and transgender women in PrEP Brasil: 48 week results of a demonstration study. The Lancet HIV, 5(3), e136–e145. doi: 10.1016/S2352-3018(18)30008-0
  • Grinsztejn, B., Jalil, E. M., Monteiro, L., Velasque, L., Moreira, R., Garcia, A. C., … Wilson, E. C. (2017). Unveiling of HIV dynamics among transgender women: A respondent-driven sampling study in Rio de Janeiro, Brazil. The Lancet HIV, 4(4), e169–e176. doi: 10.1016/S2352-3018(17)30015-2
  • Haberer, J. E. (2016). Current concepts for PrEP adherence in the PrEP revolution. Current Opinion in HIV and AIDS, 11(1), 10–17. doi: 10.1097/COH.0000000000000220
  • Herbst, J. H., Jacobs, E. D., Finlayson, T. J., McKleroy, V. S., Neumann, M. S., & Crepaz, N. (2008). Estimating HIV prevalence and risk behaviors of transgender persons in the United States: A systematic review. AIDS and Behavior, 12(1), 1–17. doi: 10.1007/s10461-007-9299-3
  • Hoagland, B., De Boni, R. B., Moreira, R. I., Madruga, J. V., Kallas, E. G., Goulart, S. P., … Veloso, V. G. (2017). Awareness and willingness to use pre-exposure prophylaxis (PrEP) among men who have sex with men and transgender women in Brazil. AIDS and Behavior, 21(5), 1278–1287. doi: 10.1007/s10461-016-1516-5
  • Jalil, E. M., Wilson, E., Velasque, L., Moreira, R. I., Hoagland, B., Castro, C., … Veloso, V. G. (2016, October). PrEP for transwomen in Rio de Janeiro, Brazil: low awareness but high willingness and candidacy to take PrEP. Poster session presented at HIV Research for Prevention, Chicago, Illinois.
  • Kuhns, L. M., Reisner, S. L., Mimiaga, M. J., Gayles, T., Shelendich, M., & Garofali, R. (2016). Correlates of PrEP indication in a multi-site cohort of young HIV-uninfected transgender women. AIDS and Behavior, 20(7), 1470–1477. doi: 10.1007/s10461-015-1182-z
  • Mascolini, M. (2011, July). TDF/FTC PrEP durable in MSM, but MSM and transgender responses differ. Paper presented at the 6th IAS conference on HIV pathogenesis, treatment and prevention, Rome, Italy. Retrieved from http://www.natap.org/2011/IAS/IAS_32.htm
  • McCormack, S., Dunn, D. T., Desai, M., Dolling, D. I., Gafos, M., Gilson, R., … Gill, O. N. (2016). Preexposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial. The Lancet, 387(10013), 53–60. doi: 10.1016/S0140-6736(15)00056-2
  • Melendez, R. M., & Pinto, R. (2007). “It’s really a hard life”: love, gender and HIV risk among male-to-female transgender persons. Culture, Health & Sexuality, 9(3), 233–245. doi: 10.1080/13691050601065909
  • Molina, J. M., Capitant, C., Spire, B., Pialoux, G., Cotte, L., Charreau, I., … Delfraissy, J. (2015). On-demand preexposure prophylaxis in men at high risk for HIV-1 infection. The New England Journal of Medicine, 373(23), 2237–2246. doi: 10.1056/NEJMoa1506273
  • Nwagwu, G. N. (2014). A phenomenological study of acceptability of preexposure prophylaxis therapy within the lived experiences of HIV negative male-to-female transgender young adults (Doctoral dissertation). Retrieved from https://search.proquest.com/docview/1544433723
  • Oldenburg, C. E., Le, B., Toan, T., Thien, D. D., Huyen, H. T., Friedman, M. R., … Colby, D. (2016). HIV pre-exposure prophylaxis indication and readiness among HIV-uninfected transgender women in Ho Chi Minh City, Vietnam. AIDS and Behavior, 20(3), 365–370. doi: 10.1007/s10461-016-1483-x
  • Operario, D., Soma, T., & Underhill, K. (2008). Sex work and HIV status among transgender women: Systematic review and meta-analysis. Journal of Acquired Immune Deficiency Syndromes, 48, 97–203. doi: 10.1097/QAI.0b013e31816e3971
  • Peng, P., Su, S., Fairley, C. K., Chu, M., Jiang, S., Zhuang, X., & Zhang, L. (2018). A global estimate of the acceptability of pre-exposure prophylaxis for HIV among men who have sex with men: A systematic review and meta-analysis. AIDS and Behavior, 22(4), 1063–1074. doi: 10.1007/s10461-017-1675-z
  • Poteat, T., Reisner, S. L., & Radix, A. (2014). HIV epidemics among transgender women. Current Opinion in HIV and AIDS, 9(2), 168–173. doi: 10.1097/COH.0000000000000030
  • Reisner, S. L., Radix, A., & Deutsch, M. B. (2016). Integrated and gender-affirming transgender clinical care and research. Journal of Acquired Immune Deficiency Syndromes, 72(3), S235–S242. doi: 10.1097/QAI.0000000000001088
  • Sevelius, J. M., Deutsch, M. B., & Grant, R. (2016a). The future of PrEP among transgender women: The critical role of gender affirmation in research and clinical practices. Journal of the International AIDS Society, 19(7(Suppl 6)). doi:10.7448/IAS.19.7.21105
  • Sevelius, J. M., Keatley, J., Calma, N., & Arnold, E. (2016b). ‘I am not a man': Trans-specific barriers and facilitators to PrEP acceptability among transgender women. Global Public Health, 11(7-8), 1060–1075. doi: 10.1080/17441692.2016.1154085
  • Soares, F., Dourado, I., Magno, L., Vasconcelos da Silva, L. A., & Nunn, A. (2017, July). Transgender women willingness to use PrEP in northeastern Brazil. Presented at the 9th IAS conference on HIV Science, Paris, France.
  • Tetteh, R. A., Yankey, B. A., Nartey, E. T., Lartey, M., Leufkens, H. G., & Dodoo, A. N. (2017). Pre-exposure prophylaxis for HIV prevention: Safety concerns. Drug Safety, 40(4), 273–283. doi: 10.1007/s40264-017-0505-6
  • Thigpen, M. C., Kebaabetswe, P. M., Paxton, L. A., Smith, D. K., Rose, C. E., Segolodi, T. M., … Brooks, J. T. (2012). Antiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana. The New England Journal of Medicine, 367(5), 423–434. doi: 10.1056/NEJMoa1110711
  • UNAIDS. (2014). Fast-track: ending the AIDS epidemic by 2030. Geneva: The Joint United Nations Programme on HIV/AIDS. Retrieved from http://www.unaids.org/en/resources/documents/2014/JC2686_WAD2014report
  • UNAIDS. (2016). Prevention gap report. Geneva: The joint United Nations programme on HIV/AIDS. Retrieved from http://www.unaids.org/en/resources/documents/2016/prevention-gap
  • UNAIDS. (2017). Ending AIDS: Progress towards the 90-90-90 targets. Geneva: The Joint United Nations Programme on HIV/AIDS. Retrieved from http://www.unaids.org/en/resources/documents/2017/20170720_Global_AIDS_update_2017
  • Uthappa, C. K., Allam, R. R., Pant, R., Pal, S., Dinaker, M., Oruganti, G., & Yeldandi, V. V. (2018). Pre-exposure prophylaxis: Awareness, acceptability and risk compensation behaviour among men who have sex with men and the transgender population. HIV Medicine, 19(4), 243–251. doi: 10.1111/hiv.12572
  • Wang, Z., Lau, J. T. F., Yang, X., Cai, Y., Gross, D. L., Ma, T., & Liu, Y. (2017). Acceptability of daily use of free oral pre-exposure prophylaxis (PrEP) among transgender women sex workers in Shenyang, China. AIDS and Behavior, 21(12), 3287–3298. doi: 10.1007/s10461-017-1869-4
  • WHO. (2012). Guidance on oral pre-exposure prophylaxis (PrEP) for serodiscordant couples, men and transgender women who have sex with men at high risk of HIV: Recommendations for use in the context of demonstration projects. Geneva: World Health Organization. Retrieved from http://www.who.int/hiv/pub/guidance_prep/en/
  • WHO. (2014). Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations. Geneva: World Health Organization. Retrieved from http://www.who.int/hiv/pub/guidelines/keypopulations/en/
  • WHO. (2016). Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: Recommendations for a public health approach - (2nd ed.). Geneva: World Health Organization. Retrieved from http://www.who.int/hiv/pub/arv/arv-2016/en/
  • Wilson, E. C., Jin, H., Liu, A., & Raymond, H. F. (2015). Knowledge, indications and willingness to take pre-exposure prophylaxis among transwomen in San Francisco, 2013. PLoS One, 10(6), e0128971. doi:10.1371/journal.pone.0128971
  • Wood, S. M., Lee, S., Barg, F. K., Castillo, M., & Dowshen, N. (2017). Young transgender women's attitudes toward HIV pre-exposure prophylaxis. Journal of Adolescent Health, 60(5), 549–555. doi: 10.1016/j.jadohealth.2016.12.004
  • Yang, D., Chariyalertsak, C., Wongthanee, A., Kawichai, S., Yotruean, K., Saokhieo, P., … Chariyalertsak, S. (2013). Acceptability of pre-exposure prophylaxis among men who have sex with men and transgender women in Northern Thailand. PLoS One, 8(10), e76650. doi:10.1371/journal.pone.0076650
  • Zalazar, V., Arístegui, I., Kerr, T., Marshall, B. D. L., Romero, M., Sued, O., & Socías, M. E. (2016). High willingness to use HIV pre-exposure prophylaxis among transgender women in Argentina. Transgender Health, 1(1), 266–273. doi: 10.1089/trgh.2016.0033

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