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AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 33, 2021 - Issue 1
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Articles

Poor rates of linkage to HIV care and uptake of treatment after home-based HIV testing among newly diagnosed 15-to-49 year-old men and women in a high HIV prevalence setting in South Africa

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Pages 70-79 | Received 22 Jan 2019, Accepted 24 Dec 2019, Published online: 09 Feb 2020

References

  • Barnabas, R. V., Van Rooyen, H., Tumwesigye, E., Murnane, P. M., Baeten, J. M., Humphries, H., … Celum, C. (2014). Initiation of antiretroviral therapy and viral suppression after home HIV testing and counselling in KwaZulu-Natal, South Africa, and Mbarara district, Uganda: A prospective, observational intervention study. The Lancet HIV, 1(2), e68–e76.
  • Bassett, I. V., Coleman, S. M., Giddy, J., Bogart, L. M., Chaisson, C. E., Ross, D., … Losina, E. (2017). Barriers to care and 1-year mortality among newly diagnosed HIV-infected people in Durban, South Africa. Journal of Acquired Immune Deficiency Syndromes, 74(4), 432–438.
  • Bassett, I. V., Regan, S., Chetty, S., Giddy, J., Uhler, L. M., Holst, H., … Losina, E. (2010). Who starts antiretroviral therapy in Durban, South Africa? … not everyone who should. AIDS, 24(Suppl 1), S37–S44.
  • Bogart, L. M., Chetty, S., Giddy, J., Sypek, A., Sticklor, L., Walensky, R. P., … Bassett, I. V. (2013). Barriers to care among people living with HIV in South Africa: Contrasts between patient and healthcare provider perspectives. AIDS Care, 25(7), 843–853.
  • Carmona, S., Bor, J., Nattey, C., Maughan-Brown, B., Maskew, M., Fox, M. P., … MacLeod, W. B. (2018). Persistent high burden of advanced HIV disease among patients seeking care in South Africa’s national HIV program: Data from a nationwide laboratory cohort. Clinical Infectious Diseases, 66(suppl_2), S111–S117.
  • Cohen, M. S., Chen, Y. Q., McCauley, M., Gamble, T., Hosseinipour, M. C., Kumarasamy, N., … Fleming, T. R. (2011). Prevention of HIV-1 infection with early antiretroviral therapy. New England Journal of Medicine, 365(6), 493–505.
  • Department of Health. (2015). National HIV testing services: Policy and guidelines 2015. Pretoria. Retrieved from https://www.nacosa.org.za/wp-content/uploads/2016/05/HTS-Policy-guideline.pdf
  • Desai, M. A., Okal, D. O., Rose, C. E., Ndivo, R., & Oyaro, B. (2017). Effect of point-of-care CD4 cell count results on linkage to care and antiretroviral initiation during a home-based HIV testing campaign: A non-blinded, cluster-randomised trial. The Lancet HIV, 4(9), e393–e401.
  • Dorward, J., Mabuto, T., Charalambous, S., Fielding, K. L., & Hoffmann, C. J. (2017). Factors associated with poor linkage to HIV care in South Africa: Secondary analysis of data from the Thol’impilo trial. Journal of Acquired Immune Deficiency Syndromes, 76(5), 453–460.
  • Fox, M. P., Larson, B., & Rosen, S. (2012). Defining retention and attrition in pre-antiretroviral HIV care: Proposals based on experience in Africa. Tropical Medicine & International Health, 17(10), 1235–1244.
  • Fox, M. P., Mazimba, A., Seidenberg, P., Crooks, D., Sikateyo, B., & Rosen, S. (2010). Barriers to initiation of antiretroviral treatment in rural and urban areas of Zambia: A cross-sectional study of cost, stigma, and perceptions about ART. Journal of the International AIDS Society, 13(1), 8.
  • Genberg, B. L., Naanyu, V., Wachira, J., Hogan, J. W., Sang, E., Nyambura, M., … Braitstein, P. (2015). Linkage to and engagement in HIV care in western Kenya: An observational study using population-based estimates from home-based counselling and testing. The Lancet HIV, 2(1), e20–e26.
  • Govindasamy, D., Ford, N., & Kranzer, K. (2012). Risk factors, barriers and facilitators for linkage to antiretroviral therapy care: A systematic review. AIDS, 26(16), 2059–2067.
  • Govindasamy, D., Kranzer, K., van Schaik, N., Noubary, F., Wood, R., Walensky, R. P., … Pett, S. (2013). Linkage to HIV, TB and non-communicable disease care from a mobile testing unit in Cape Town, South Africa. PLoS ONE, 8(11), e80017.
  • Govindasamy, D., van Schaik, N., Kranzer, K., Wood, R., Mathews, C., & Bekker, L.-G. (2011). Linkage to HIV care from a mobile testing unit in South Africa by different CD4 count strata. Journal of Acquired Immune Deficiency Syndromes, 58(3), 344–352.
  • Hachfeld, A., Ledergerber, B., Darling, K., Weber, R., Calmy, A., Battegay, M., … Wandeler, G. (2015). Reasons for late presentation to HIV care in Switzerland. Journal of the International AIDS Society, 18(1), 20317.
  • Hatcher, A. M., Turan, J. M., Leslie, H. H., Kanya, L. W., Kwena, Z., Johnson, M. O., … Cohen, C. R. (2012). Predictors of linkage to care following community-based HIV counseling and testing in rural Kenya. AIDS and Behavior, 16(5), 1295–1307.
  • Hoffmann, C. J., Mabuto, T., Ginindza, S., Fielding, K. L., Kubeka, G., Dowdy, D. W., … Charalambous, S. (2017). Strategies to accelerate HIV care and antiretroviral therapy initiation after HIV diagnosis: A randomized trial. Journal of Acquired Immune Deficiency Syndromes, 75(5), 540–547.
  • Horter, S., Thabede, Z., Dlamini, V., Bernays, S., Stringer, B., Mazibuko, S., … Jobanputra, K. (2017). “Life is so easy on ART, once you accept it”: Acceptance, denial and linkage to HIV care in Shiselweni, Swaziland. Social Science & Medicine (1982), 176, 52–59.
  • The INSIGHT START Study Group. (2015). Initiation of antiretroviral therapy in early asymptomatic HIV infection. New England Journal of Medicine, 373(9), 795–807.
  • Iwuji, C. C., Orne-Gliemann, J., Larmarange, J., Okesola, N., Tanser, F., Thiebaut, R., … Low, N. (2016). Uptake of home-based HIV testing, linkage to care, and community attitudes about ART in rural KwaZulu-Natal, South Africa: Descriptive results from the first phase of the ANRS 12249 TasP cluster-randomised trial. PLoS Medicine, 13(8), e1002107.
  • Johnson, L. F., Mossong, J., Dorrington, R. E., Schomaker, M., Hoffmann, C. J., Keiser, O., … Celentano, D. D. (2013). Life expectancies of South African adults starting antiretroviral treatment: Collaborative analysis of cohort studies. PLoS Medicine, 10(4), e1001418.
  • Kalichman, S., Simbayi, L., Jooste, S., Toefy, Y., Cain, D., Cherry, C., & Kagee, A. (2005). Development of a brief scale to measure AIDS-related stigma in South Africa. AIDS and Behavior, 9(2), 135–143.
  • Katz, I. T., Dietrich, J., Tshabalala, G., Essien, T., Rough, K., Wright, A. A., … Ware, N. C. (2015). Understanding treatment refusal among adults presenting for HIV-testing in Soweto, South Africa: A qualitative study. AIDS and Behavior, 19(4), 704–714.
  • Katz, I. T., Essien, T., Marinda, E. T., Gray, G. E., Bangsberg, D. R., Martinson, N. A., & de Bruyn, G. (2011). Antiretroviral therapy refusal among newly diagnosed HIV-infected adults. AIDS, 25(17), 2177–2181.
  • Katz, I. T., & Maughan-Brown, B. (2017). Improved life expectancy of people living with HIV: Who is left behind? The Lancet HIV, 4(8), e324–e326.
  • Kelly, J. D., Hartman, C., Graham, J., Kallen, M. A., & Giordano, T. P. (2014). Social support as a predictor of early diagnosis, linkage, retention, and adherence to HIV care: Results from the steps study. Journal of the Association of Nurses in AIDS Care, 25(5), 405–413.
  • Kharsany, A. B., Cawood, C., Khanyile, D., Grobler, A., Mckinnon, L. R., Samsunder, N., … Bere, A. (2015). Strengthening HIV surveillance in the antiretroviral therapy era: Rationale and design of a longitudinal study to monitor HIV prevalence and incidence in the uMgungundlovu District, KwaZulu-Natal, South Africa. BMC Public Health, 15, 1149.
  • Labhardt, N. D., Ringera, I., Lejone, T. I., Klimkait, T., Muhairwe, J., Amstutz, A., & Glass, T. R. (2018). Effect of offering same-day ART vs usual health facility referral during home-based HIV testing on linkage to care and viral suppression among adults with HIV in Lesotho. Journal of the American Medical Association, 319(11), 1103–1111.
  • Lahuerta, M., Wu, Y., Hoffman, S., Elul, B., Kulkarni, S. G., Remien, R. H., … Nash, D. (2014). Advanced HIV disease at entry into HIV care and initiation of antiretroviral therapy during 2006–2011: Findings from four sub-saharan African countries. Clinical Infectious Diseases, 58(3), 432–441.
  • Lewis, L., Maughan-Brown, B., Grobler, A., Cawood, C., Khanyile, D., Glenshaw, M., & Kharsany, A. B. M. (2019). Impact of home-based HIV testing services on progress toward the UNAIDS 90-90-90 targets in a hyperendemic area of South Africa. Journal of Acquired Immune Deficiency Syndromes, 80(2), 135–144.
  • MacKellar, D. A., Williams, D., Storer, N., Okello, V., Azih, C., Drummond, J., … Shankar, E. M. (2016). Enrollment in HIV care two years after HIV diagnosis in the kingdom of Swaziland: An evaluation of a national program of new linkage procedures. PLoS ONE, 11(2), e0150086.
  • Maughan-Brown, B., Kuo, C., Galárraga, O., Smith, P., Lurie, M. N., Bekker, L.-G., & Harrison, A. (2018). Stumbling blocks at the clinic: Experiences of seeking HIV treatment and care in South Africa. AIDS and Behavior, 22(3), 765–773.
  • Maughan-Brown, B., Smith, P., Kuo, C., Harrison, A., Lurie, M., Bekker, L.-G., & Galárraga, O. (2018). Readiness for antiretroviral therapy: Implications for linking HIV-infected individuals to care and treatment. AIDS and Behavior, 22(3), 691–700.
  • Maughan-Brown, B., & Venkataramani, A. (2018). Accuracy and determinants of perceived HIV risk among young women in South Africa. BMC Public Health, 18, 42.
  • Medley, A., Ackers, M., Amolloh, M., Owuor, P., Muttai, H., Audi, B., … Laserson, K. (2013). Early uptake of HIV clinical care after testing HIV-positive during home-based testing and counseling in western Kenya. AIDS and Behavior, 17(1), 224–234.
  • Motsoaledi, A. (2016). Health department budget vote speech 2016/17. Pretoria: Department of Health.
  • Mugglin, C., Estill, J., Wandeler, G., Bender, N., Egger, M., Gsponer, T., & Keiser, O. (2012). Loss to programme between HIV diagnosis and initiation of antiretroviral therapy in sub-Saharan Africa: Systematic review and meta-analysis. Tropical Medicine & International Health, 17(12), 1509–1520.
  • Naik, R., Doherty, T., Jackson, D., Tabana, H., Swanevelder, S., Thea, D. M., … Fox, M. P. (2015). Linkage to care following a home-based HIV counselling and testing intervention in rural South Africa. Journal of the International AIDS Society, 18(1), 19843.
  • Nakigozi, G., Atuyambe, L., Kamya, M., Makumbi, F. E., Chang, L. W., Nakyanjo, N., … Gray, R. (2013). A qualitative study of barriers to enrollment into free HIV care: Perspectives of never-in-care HIV-positive patients and providers in Rakai, Uganda. BioMed Research International, 2013(4), 470245.
  • Parker, L. A., Jobanputra, K., Rusike, L., Mazibuko, S., Okello, V., Kerschberger, B., … Teck, R. (2015). Feasibility and effectiveness of two community-based HIV testing models in rural Swaziland. Tropical Medicine & International Health, 20(7), 893–902.
  • Paz-Bailey, G., Pham, H., Oster, A. M., Lansky, A., Bingham, T., Wiegand, R. E., … Heffelfinger, J. D. (2014). Engagement in HIV care among HIV-positive men who have sex with men from 21 cities in the United States. AIDS and Behavior, 18(S3), 348–358.
  • Plazy, M., Dray-Spira, R., Orne-Gliemann, J., Dabis, F., & Newell, M.-L. (2014). Continuum in HIV care from entry to ART initiation in rural KwaZulu-Natal, South Africa. Tropical Medicine & International Health, 19(6), 680–689.
  • Radloff, L. S. (1977). The CES-D scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1(3), 385–401.
  • Ruzagira, E., Baisley, K., Kamali, A., Biraro, S., & Grosskurth, H. (2017). Linkage to HIV care after home-based HIV counselling and testing in sub-Saharan Africa: A systematic review. Tropical Medicine & International Health, 22(7), 807–821.
  • Sharma, M., Ying, R., Tarr, G., & Barnabas, R. (2015). Systematic review and meta-analysis of community and facility-based HIV testing to address linkage to care gaps in sub-Saharan Africa. Nature, 528(7580), S77–S85.
  • Smith, L. R., Amico, K. R., Shuper, P. A., Christie, S., Fisher, W. A., Cornman, D. H., … Fisher, J. D. (2013). Information, motivation, and behavioral skills for early pre-ART engagement in HIV care among patients entering clinical care in KwaZulu-Natal, South Africa. AIDS Care, 25(12), 1485–1490.
  • Stinson, K., & Myer, L. (2012). Barriers to initiating antiretroviral therapy during pregnancy: A qualitative study of women attending services in Cape Town, South Africa. African Journal of AIDS Research, 11(1), 65–73.
  • Suthar, A. B., Ford, N., Bachanas, P. J., Wong, V. J., Rajan, J. S., Saltzman, A. K., … Sansom, S. L. (2013). Towards universal voluntary HIV testing and counselling: A systematic review and meta-analysis of community-based approaches. PLoS Medicine, 10(8), e1001496.
  • UNAIDS. (2014). The gap report. Geneva: Author.
  • Van Rooyen, H., Barnabas, R. V., Baeten, J. M., Phakathi, Z., Joseph, P., Krows, M., … Celum, C. (2013). High HIV testing uptake and linkage to care in a novel program of home-based HIV counseling and testing with facilitated referral in KwaZulu-Natal, South Africa. Journal of Acquired Immune Deficiency Syndromes, 64(1), e1–e8.
  • WHO. (2016). Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Geneva: Author.
  • Wringe, A., Roura, M., Urassa, M., Busza, J., Athanas, V., & Zaba, B. (2009). Doubts, denial and divine intervention: Understanding delayed attendance and poor retention rates at a HIV treatment programme in rural Tanzania. AIDS Care, 21(5), 632–637.

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