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Review Article

Co-occurring psychiatric conditions in autism spectrum disorder

ORCID Icon, , & ORCID Icon
Pages 40-61 | Received 15 Nov 2017, Accepted 04 Mar 2018, Published online: 23 Apr 2018

References

  • Achenbach, T.M. (1966). The classification of children’s psychiatric symptoms: A factor-analytic study. Psychological Monographs: General and Applied, 80, 1–37. doi:10.1037/h0093906
  • American Psychiatric Association. (1980). Diagnostic and statistical manual of mental disorders (3rd ed.). Washington, DC: American Psychiatric Association.
  • American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed. tr). Washington, DC: Author.
  • American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.
  • Antshel, K.M., Zhang-James, Y., Wagner, K.E., Ledesma, A., & Faraone, S.V. (2016). An update on the comorbidity of ADHD and ASD: A focus on clinical management. Expert Review of Neurotherapeutics, 16, 279–293. doi:10.1586/14737175.2016.1146591
  • Bakken, T.L., Helverschou, S.B., Eilertsen, D.E., Heggelund, T., Myrbakk, E., & Martinsen, H. (2010). Psychiatric disorders in adolescents and adults with autism and intellectual disability: A representative study in one county in Norway. Research in Developmental Disabilities, 31, 1669–1677. doi:10.1016/j.ridd.2010.04.009
  • Berument, S.K., Rutter, M., Lord, C., Pickles, A., & Bailey, A. (1999). Autism screening questionnaire: Diagnostic validity. The British Journal of Psychiatry, 175, 444–451. doi:10.1192/bjp.175.5.444
  • Bögels, S., Hoogstad, B., van Dun, L., de Schutter, S., & Restifo, K. (2008). Mindfulness training for adolescents with externalizing disorders and their parents. Behavioural and Cognitive Psychotherapy, 36, 193–209. doi:10.1017/S1352465808004190
  • Bons, D., Van Den Broek, E., Scheepers, F., Herpers, P., Rommelse, N., & Buitelaaar, J.K. (2013). Motor, emotional, and cognitive empathy in children and adolescents with autism spectrum disorder and conduct disorder. Journal of Abnormal Child Psychology, 41, 425–443. doi:10.1007/s10802-012-9689-5
  • Butwicka, A., Långström, N., Larsson, H., Lundström, S., Serlachius, E., Almqvist, C., … Lichtenstein, P. (2017). Increased risk for substance use-related problems in autism spectrum disorders: A population-based cohort study. Journal of Autism and Developmental Disorders, 47, 80–89. doi:10.1007/s10803-016-2914-2
  • Cage, E., Di Monaco, J., & Newell, V. (2017). Experiences of autism acceptance and mental health in autistic adults. Journal of Autism and Developmental Disorders, 48, 5–8. doi:10.1007/s10803-017-3342-7
  • Cai, R.Y., Richdale, A.L., Dissanayake, C., & Uljarević, M. (2018). Brief report: Inter-relationship between emotion regulation, intolerance of uncertainty, anxiety, and depression in youth with autism spectrum disorder. Journal of Autism and Developmental Disorders, 48, 316–325. doi:10.1007/s10803-017-3318-7
  • Cassidy, S., Bradley, L., Bowen, E., Wigham, S., & Rodgers, J. (2018). Measurement properties of tools used to assess suicidality in adults with and without autism spectrum conditions: A systematic review. Autism Research. Retrieved from https://doi.org/10.1002/aur.1922
  • Cassidy, S., Bradley, P., Robinson, J., Allison, C., McHugh, M., & Baron-Cohen, S. (2014). Suicidal ideation and suicide plans or attempts in adults with asperger’s syndrome attending a specialist diagnostic clinic: A clinical cohort study. The Lancet Psychiatry, 1, 142–147. doi:10.1016/S2215-0366(14)70248-2
  • Chandrasekhar, T., & Sikich, L. (2015). Challenges in the diagnosis and treatment of depression in autism spectrum disorders across the lifespan. Dialogues in Clinical Neuroscience, 17, 219–227.
  • Chang, Y., Quan, J., & Wood, J.J. (2012). Effects of anxiety disorder severity on social functioning in children with autism spectrum disorders. Journal of Developmental and Physical Disabilities, 24, 235–245. doi:10.1007/s10882-012-9268-2
  • Christensen, D.L., Baio, J., Braun, K.V.N., Bilder, D., Charles, J., Constantino, J.N., … Yeargin-Allsopp, M. (2016). Prevalence and characteristics of autism spectrum disorder among children aged 8 years - autism and developmental disabilities monitoring network, 11 sites, United States, 2012. Morbidity and Mortality Weekly Report. Surveillance Summaries, 65, 1–23. doi:10.15585/mmwr.ss6503a1
  • Conner, C.M., & White, S.W. (2017). Brief report: Feasibility and preliminary efficacy of individual mindfulness therapy for adults with autism spectrum disorder. Journal of Autism and Developmental Disorders, 48, 290–300. doi:10.1007/s10803-017-3312-0
  • Craig, F., Lamanna, A.L., Margari, F., Matera, E., Simone, M., & Margari, L. (2015). Overlap between autism spectrum disorders and attention deficit hyperactivity disorder: Searching for distinctive/common clinical features. Autism Research, 8, 328–337. doi:10.1002/aur.1449
  • Croen, L.A., Shankute, N., Davignon, M., Massolo, M.L., & Yoshida, C. (2017). Demographic and clinical characteristics associated with engagement in behavioral health treatment among children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 47, 3347–3357. doi:10.1007/s10803-017-3247-5
  • Damiano, C.R., Mazefsky, C.A., White, S.W., & Dichter, G.S. (2014). Future directions for research in autism spectrum disorders. Journal of Clinical Child and Adolescent Psychology, 43, 828–843. doi:10.1080/15374416.2014.945214
  • Danial, J.T., & Wood, J.J. (2013). Cognitive behavioral therapy for children with autism: Review and considerations for future research. Journal of Developmental and Behavioral Pediatrics, 34, 702–715. doi:10.1097/DBP.0b013e31829f676c
  • De-la-Iglesia, M., & Olivar, J.-S. (2015). Risk factors for depression in children and adolescents with high functioning autism spectrum disorders. The Scientific World Journal, 2015, 127853. https://doi.org/10.1155/2015/127853
  • De Bruin, E.I., Ferdinand, R.F., Meester, S., De Nijs, P.F.A., & Verheij, F. (2007). High rates of psychiatric co-morbidity in PDD-NOS. Journal of Autism and Developmental Disorders, 37, 877–886. doi:10.1007/s10803-006-0215-x
  • Eack, S.M., Bahorik, A.L., McKnight, S.A.F., Hogarty, S.S., Greenwald, D.P., Newhill, C.E., … Minshew, N.J. (2013). Commonalities in social and non-social cognitive impairments in adults with autism spectrum disorder and schizophrenia. Schizophrenia Research, 148, 24–28. doi:10.1016/j.schres.2013.05.013
  • Eaton, N.R., Krueger, R.F., Keyes, K.M., Wall, M., Hasin, D.S., Markon, K.E., … Grant, B.F. (2013). The structure and predictive validity of internalizing disorders. Journal of Abnormal Psychology, 122, 86–92. doi:10.1037/a0029598
  • Eaton, N.R., Rodriguez-Seijas, C., Carragher, N., & Krueger, R.F. (2015). Transdiagnostic factors of psychopathology and substance use disorders: A review. Social Psychiatry and Psychiatric Epidemiology, 50, 171–182. doi:10.1007/s00127-014-1001-2
  • Ehlers, S., Gillberg, C., & Wing, L. (1999). A screening questionnaire for asperger syndrome and other high-functioning autism spectrum disorders in school age children. Journal of Autism and Developmental Disorders, 29, 129–141. doi:10.1023/A:1023040610384
  • Evans, D.W., Canavera, K., Kleinpeter, F.L., Maccubbin, E., & Taga, K. (2005). The fears, phobias and anxieties of children with autism spectrum disorders and down syndrome: Comparisons with developmentally and chronologically age matched children. Child Psychiatry and Human Development, 36, 3–26. doi:10.1007/s10578-004-3619-x
  • Frazier, J.A., Doyle, R., Chiu, S., & Coyle, J.T. (2002). Treating a child with Asperger's disorder and comorbid bipolar disorder. American Journal of Psychiatry, 159, 13–21. doi:10.1176/appi.ajp.159.1.13
  • Frazier, T.W., Youngstrom, E.A., Embacher, R., Hardan, A.Y., Constantino, J.N., Law, P., … Eng, C. (2014). Demographic and clinical correlates of autism symptom domains and autism spectrum diagnosis. Autism, 18, 571–582. doi:10.1177/1362361313481506
  • Fung, L.K., Mahajan, R., Nozzolillo, A., Bernal, P., Krasner, A., Jo, B., … Hardan, A.Y. (2016). Pharmacologic treatment of severe irritability and problem behaviors in Autism: A systematic review and meta-analysis. Pediatrics, 137, S124–S135. doi:10.1542/peds.2015-2851K
  • Gadow, K.D. (2012). Schizophrenia spectrum and attention-deficit/hyperactivity disorder symptoms in autism spectrum disorder and controls. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 1076–1084. doi:10.1016/j.jaac.2012.08.001
  • Gadow, K.D., & DeVincent, C.J. (2005). Clinical significance of tics and attention-deficit hyperactivity disorder (ADHD) in children with pervasive developmental disorder. Journal of Child Neurology, 20, 481–488. doi:10.1177/08830738050200060301
  • Gadow, K.D., DeVincent, C.J., & Drabick, D.A.G. (2008). Oppositional defiant disorder as a clinical phenotype in children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 38, 1302–1310. doi:10.1007/s10803-007-0516-8
  • Gadow, K.D., DeVincent, C.J., Pomeroy, J., & Azizian, A. (2004). Psychiatric symptoms in preschool children with PDD and clinic and comparison samples. Journal of Autism and Developmental Disorders, 34, 379–393. doi:10.1023/B:JADD.0000037415.21458.93
  • Gadow, K.D., DeVincent, C.J., Siegal, V.I., Olvet, D.M., Kibria, S., Kirsch, S.F., & Hatchwell, E. (2013). Allele-specific associations of 5-HTTLPR/rs25531 with ADHD and autism spectrum disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 40, 292–297. doi:10.1016/j.pnpbp.2012.10.019
  • Gadow, K.D., & Sprafkin, J. (2000). Early childhood symptom inventory-4 screening manual. Stony Brook, NY: Checkmate Plus.
  • Gadow, K.D., & Sprafkin, J. (2002). Child symptom inventory-4 screening and norms manual. Stony Brook, NY: Checkmate Plus.
  • Gotham, K., Brunwasser, S.M., & Lord, C. (2015a). Depressive and anxiety symptom trajectories from school-age through young adulthood in samples with autism spectrum disorder and developmental delay. Journal of the American Academy of Child & Adolescent Psychiatry, 54, 269–376. doi:10.1016/j.jaac.2015.02.005
  • Gotham, K., Unruh, K., & Lord, C. (2015b). Depression and its measurement in verbal adolescents and adults with autism spectrum disorder. Autism, 19, 491–504. doi:10.1177/1362361314536625
  • Greenlee, J.L., Mosley, A.S., Shui, A.M., Veenstra-VanderWeele, J., & Gotham, K.O. (2016). Medical and behavioral correlates of depression history in children and adolescents with autism spectrum disorder. Pediatrics, 137(Supplement), S105–S114. https://doi.org/10.1542/peds.2015-2851I
  • Grzadzinski, R., Di Martino, A., Brady, E., Mairena, M.A., O’neale, M., Petkova, E., … Castellanos, F.X. (2011). Examining autistic traits in children with ADHD: Does the autism spectrum extend to ADHD? Journal of Autism and Developmental Disorders, 41, 1178–1191. doi:10.1007/s10803-010-1135-3
  • Grzadzinski, R., Dick, C., Lord, C., & Bishop, S. (2016). Parent-reported and clinician-observed autism spectrum disorder (ASD) symptoms in children with attention deficit/hyperactivity disorder (ADHD): Implications for practice under DSM-5. Molecular Autism, 7, 7. doi:10.1186/s13229-016-0072-1
  • Gurney, J.G., McPheeters, M.L., & Davis, M.M. (2006). Parental report of health conditions and health care use among children with and without autism. Archives of Pediatrics & Adolescent Medicine, 160, 825–830. doi:10.1001/archpedi.160.8.825
  • Guttmann-Steinmetz, S., Gadow, K.D., DeVincent, C.J., & Crowell, J. (2010). Anxiety symptoms in boys with autism spectrum disorder, attention-deficit hyperactivity disorder, or chronic multiple tic disorder and community controls. Journal of Autism and Developmental Disorders, 40, 1006–1016. doi:10.1007/s10803-010-0950-x
  • Hofvander, B., Delorme, R., Chaste, P., Nydén, A., Wentz, E., Ståhlberg, O., … Leboyer, M. (2009). Psychiatric and psychosocial problems in adults with normal-intelligence autism spectrum disorders. BMC Psychiatry, 9, 35. doi:10.1186/1471-244X-9-35
  • Holtmann, M., Bölte, S., & Poustka, F. (2007a). Attention deficit hyperactivity disorder symptoms in pervasive developmental disorders: Association with autistic behavior domains and coexisting psychopathology. Psychopathology, 40, 172–177. doi:10.1159/000100007
  • Holtmann, M., Bölte, S., & Poustka, F. (2007b). Autism spectrum disorders: Sex differences in autistic behaviour domains and coexisting psychopathology. Developmental Medicine and Child Neurology, 49, 361–366. doi:10.1111/j.1469-8749.2007.00361.x
  • Hoover, D.W. (2015). The effects of psychological trauma on children with autism spectrum disorders: A research review. Review Journal of Autism and Developmental Disorders, 2, 287–299. doi:10.1007/s40489-015-0052-y
  • Hughes, C., Russell, J., & Robbins, T.W. (1994). Evidence for executive dysfunction in autism. Neuropsychologia, 32, 477–492. doi:10.1016/0028-3932(94)90092-2
  • Huke, V., Turk, J., Saeidi, S., Kent, A., & Morgan, J.F. (2013). Autism spectrum disorders in eating disorder populations: A systematic review. European Eating Disorders Review, 21, 345–351. doi:10.1002/erv.2244
  • Hunt, J.I., Case, B.G., Birmaher, B., Stout, R.L., Dickstein, D.P., Yen, S., … Keller, M.B. (2013). Irritability and elation in a large bipolar youth sample: Relative symptom severity and clinical outcomes over 4 years. Journal of Clinical Psychiatry, 74, e110–e117. doi:10.4088/JCP.12m07874
  • Hurtig, T., Kuusikko, S., Mattila, M.-L., Haapsamo, H., Ebeling, H., Jussila, K., … Moilanen, I. (2009). Multi-informant reports of psychiatric symptoms among high-functioning adolescents with asperger syndrome or autism. Autism, 13, 583–598. doi:10.1177/1362361309335719
  • Joshi, G., Biederman, J., Petty, C., Goldin, R.L., Furtak, S.L., & Wozniak, J. (2013a). Examining the comorbidity of bipolar disorder and autism spectrum disorders: A large controlled analysis of phenotypic and familial correlates in a referred population of youth with bipolar i disorder with and without autism spectrum disorders. Journal of Clinical Psychiatry, 74, 578–586. doi:10.4088/JCP.12m07392
  • Joshi, G., Faraone, S.V., Wozniak, J., Petty, C., Fried, R., Galdo, M., … Biederman, J. (2014). Examining the clinical correlates of autism spectrum disorder in youth by ascertainment source. Journal of Autism and Developmental Disorders, 44, 2117–2126. doi:10.1007/s10803-014-2063-4
  • Joshi, G., Wozniak, J., Petty, C., Martelon, M.K., Fried, R., Bolfek, A., … Biederman, J. (2013b). Psychiatric comorbidity and functioning in a clinically referred population of adults with autism spectrum disorders: A comparative study. Journal of Autism and Developmental Disorders, 43, 1314–1325. doi:10.1007/s10803-012-1679-5
  • Kaat, A.J., & Lecavalier, L. (2013). Disruptive behavior disorders in children and adolescents with autism spectrum disorders: A review of the prevalence, presentation, and treatment. Research in Autism Spectrum Disorders, 7, 1579–1594. doi:10.1016/j.rasd.2013.08.012
  • Kanner, L. (1968). Autistic disturbances of affective contact. Nervous Child, 35, 100–136. doi:10.1105/tpc.11.5.949
  • Kerns, C.M., & Kendall, P.C. (2012). The presentation and classification of anxiety in autism spectrum disorder. Clinical Psychology-Science and Practice, 19, 323–347. doi:10.1111/cpsp.12009
  • Kerns, C.M., Renno, P., Kendall, P.C., Berry, L., Souders, M.C., Franklin, M.E., Schultz, R.T., … Herrington, J. (2014). Traditional and atypical presentations of anxiety in youth with autism spectrum disorder. Journal of Autism and Developmental Disorders, 44, 2851–2861. doi:10.1007/s10803-014-2141-7
  • Kerns, C.M., Kendall, P.C., Wood, J.J., & Storch, E.A. (2016). Anxiety disorders interview schedule – autism addendum: Reliability and validity in children with autism spectrum disorder. Journal of Clinical Child & Adolescent Psychology, 46, 88–100. doi:10.1080/15374416.2016.1233501
  • Kerns, C.M., Kendall, P.C., Zickgraf, H., Franklin, M.E., Miller, J., & Herrington, J. (2015a). Not to be overshadowed or overlooked: Functional impairments associated with comorbid anxiety disorders in youth with ASD. Behavior Therapy, 46, 29–39. doi:10.1016/j.beth.2014.03.005
  • Kerns, C.M., Moskowitz, L., Rosen, T.E., Drahota, A., Wainer, A., Josephson, A., … Lerner, M.D. (2018). A multi-site, multidisciplinary Delphi consensus study describing “usual care” intervention practices for school- to transition-age youth with autism. Journal of Clinical Child and Adolescent Psychology, 1-22. doi:https://doi.org/10.1080/15374416.2017.1410826
  • Kerns, C.M., Newschaffer, C.J., & Berkowitz, S.J. (2015b). Traumatic childhood events and autism spectrum disorder. Journal of Autism and Developmental Disorders, 45, 3475–3486. doi:10.1007/s10803-015-2392-y
  • Kerns, C.M., Roux, A.M., Connell, J.E., & Shattuck, P.T. (2016). Adapting cognitive behavioral techniques to address anxiety and depression in cognitively able emerging adults on the autism spectrum. Cognitive and Behavioral Practice, 23, 329–340. doi:10.1016/j.cbpra.2016.06.002
  • Kerns, C.M., Rump, K., Worley, J., Kratz, H., McVey, A., Herrington, J., & Miller, J. (2016). The differential diagnosis of anxiety disorders in cognitively-able youth with autism. Cognitive and Behavioral Practice, 23, 530–547. doi:10.1016/j.cbpra.2015.11.004
  • Kessler, R.C., Chiu, W.T., Demler, O., & Walters, E.E. (2005). Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the national comorbidity survey replication. Arch Gen Psychiatry, 62, 617–627. doi:10.1001/archpsyc.62.6.617
  • Kim, H., & Eaton, N.R. (2015). The hierarchical structure of common mental disorders: Connecting multiple levels of comorbidity, bifactor models, and predictive validity. Journal of Abnormal Psychology, 124, 1064–1078. doi:10.1037/abn0000113
  • Konstantareas, M.M., & Hewitt, T. (2001). Autistic disorder and schizophrenia: diagnostic overlaps. [Article]. Journal of Autism & Developmental Disorders, 31, 19–28. doi:10.1023/A:1005605528309
  • Lainhart, J.E., & Folstein, S.E. (1994). Affective disorders in people with autism: A review of published cases. Journal of Autism and Developmental Disorders, 24, 587–601. doi:10.1007/BF02172140
  • Larson, F.V., Wagner, A.P., Jones, P.B., Tantam, D., Lai, M.C., Baron-Cohen, S., & Holland, A.J. (2017). Psychosis in autism: Comparison of the features of both conditions in a dually affected cohort. British Journal of Psychiatry, 210, 269–275. doi:10.1192/bjp.bp.116.187682
  • Lecavalier, L., Gadow, K.D., DeVincent, C.J., & Edwards, M.C. (2008). Validation of DSM-IV model of psychiatric syndromes in children with autism spectrum disorders. Journal of Autism & Developmental Disorders, 39, 278–289. doi:10.1007/s10803-008-0622-2
  • Lecavalier, L., Gadow, K.D., DeVincent, C.J., Houts, C.R., & Edwards, M.C. (2011). Validity of DSM-IV syndromes in preschoolers with autism spectrum disorders. Autism, 15, 527–543. doi:10.1177/1362361310391115
  • Leitner, Y. (2014). The co-occurrence of autism and attention deficit hyperactivity disorder in children -what do we know?. Frontiers in Human Neuroscience, 8, 1–8. doi:10.3389/fnhum.2014.00268
  • Lerner, M.D., Mazefsky, C.A., Weber, R.J., Transue, E., Siegel, M., & Gadow, K.D. (2017). Verbal ability and psychiatric symptoms in clinically referred inpatient and outpatient youth with ASD. Journal of Autism and Developmental Disorders. Retrieved from https://doi.org/10.1007/s10803-017-3344-5
  • Lever, A.G., & Geurts, H.M. (2016). Psychiatric co-occurring symptoms and disorders in young, middle-aged, and older adults with autism spectrum disorder. Journal of Autism and Developmental Disorders, 46, 1916–1930. doi:10.1007/s10803-016-2722-8
  • Leverich, G.S., & Post, R.M. (2006). Course of bipolar illness after history of childhood trauma. Lancet, 367, 1040–1042. doi:10.1016/S0140-6736(06)68450-X
  • Levy, S.E., Giarelli, E., Lee, L.C., Schieve, L.A., Kirby, R.S., Cunniff, C., … Rice, C.E. (2010). Autism spectrum disorder and co-occurring developmental, psychiatric, and medical conditions among children in multiple populations of the United States. Journal of Developmental and Behavioral Pediatrics, 31, 267–275. doi:10.1097/DBP.0b013e3181d5d03b
  • Leyfer, O.T., Folstein, S.E., Bacalman, S., Davis, N.O., Dinh, E., Morgan, J., … Lainhart, J.E. (2006). Comorbid psychiatric disorders in children with autism: Interview development and rates of disorders. Journal of Autism and Developmental Disorders, 36, 849–861. doi:10.1007/s10803-006-0123-0
  • Lord, C., Rutter, M., DiLavore, P.C., Risi, S., Gotham, K., & Bishop, S. (2012). Manual for the autism diagnostic observation schedule, second edition: ADOS-2. Los Angeles, CA: Western Psychological Services.
  • Lord, C., Rutter, M., & Le Couteur, A. (1994). Autism diagnostic interview-revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 659–685. doi:10.1007/BF02172145
  • Magnuson, K.M., & Constantino, J.N. (2011). Characterization of depression in children with autism spectrum disorders. Journal of Developmental and Behavioral Pediatrics: JDBP, 32, 332–340. doi:10.1097/DBP.0b013e318213f56c
  • Mahajan, R., Bernal, M.P., Panzer, R., Whitaker, A., Roberts, W., Handen, B., … Veenstra-VanderWeele, J. (2012). Clinical practice pathways for evaluation and medication choice for attention-deficit/hyperactivity disorder symptoms in autism spectrum disorders. Pediatrics, 130(Supplement 2), S125–S138. doi:10.1542/peds.2012-0900J
  • Mandell, D.S. (2010). Disparities in diagnosis received prior to a diagnosis of autism spectrum disorder. Autism, 37, 1795–1802. doi:10.1007/s10803-006-0314-8.Disparities
  • Mandell, D.S., Ittenbach, R.F., Levy, S.E., & Pinto-Martin, J.A. (2007). Disparities in diagnoses received prior to a diagnosis of autism spectrum disorder. Journal of Autism and Developmental Disorders, 37, 1795–1802. doi:10.1007/s10803-006-0314-8
  • Mandell, D.S., Lawer, L.J., Branch, K., Brodkin, E.S., Healey, K., Witalec, R., … Gur, R.E. (2012). Prevalence and correlates of autism in a state psychiatric hospital. Autism, 16, 557–567. doi:10.1177/1362361311412058
  • Mandell, D.S., Morales, K.H., Marcus, S.C., Stahmer, A.C., Doshi, J., & Polsky, D.E. (2008). Psychotropic medication use among medicaid-enrolled children with autism spectrum disorders. Pediatrics, 121, e441–e448. doi:10.1542/peds.2007-0984
  • Mandy, W., Chilvers, R., Chowdhury, U., Salter, G., Seigal, A., & Skuse, D. (2012). Sex differences in autism spectrum disorder: Evidence from a large sample of children and adolescents. Journal of Autism and Developmental Disorders, 42, 1304–1313. doi:10.1007/s10803-011-1356-0
  • Martin, J., Hamshere, M.L., O’donovan, M.C., Rutter, M., & Thapar, A. (2014). Factor structure of autistic traits in children with ADHD. Journal of Autism and Developmental Disorders, 44, 204–215. doi:10.1007/s10803-013-1865-0
  • Matson, J.L., & Cervantes, P.E. (2014). Commonly studied comorbid psychopathologies among persons with autism spectrum disorder. Research in Developmental Disabilities, 35, 952–962. Elsevier Ltd. doi:10.1016/j.ridd.2014.02.012
  • Mattila, M.L., Hurtig, T., Haapsamo, H., Jussila, K., Kuusikko-Gauffin, S., Kielinen, M., … Moilanen, I. (2010). Comorbid psychiatric disorders associated with asperger syndrome/high-functioning autism: A community- and clinic-based study. Journal of Autism and Developmental Disorders, 40, 1080–1093. doi:10.1007/s10803-010-0958-2
  • Maughan, B., Rowe, R., Messer, J., Goodman, R., & Meltzer, H. (2004). Conduct disorder and oppositional defiant disorder in a national sample: Developmental epidemology. Journal of Child Psychology and Psychiatry, 45, 609–621. doi:10.1111/j.1469-7610.2004.00250.x
  • Mayes, S.D., Calhoun, S.L., Mayes, R.D., & Molitoris, S. (2012). Autism and ADHD: Overlapping and discriminating symptoms. Research in Autism Spectrum Disorders, 6, 277–285. doi:10.1016/j.rasd.2011.05.009
  • Mayes, S.D., Gorman, A.A., Hillwig-Garcia, J., & Syed, E. (2013). Suicide ideation and attempts in children with autism. Research in Autism Spectrum Disorders, 7, 109–119. doi:10.1016/j.rasd.2012.07.009
  • Mazefsky, C.A. (2015). Emotion regulation and emotional distress in autism spectrum disorder: Foundations and considerations for future research. Journal of Autism and Developmental Disorders, 45, 3405–3408. doi:10.1007/s10803-015-2602-7
  • Mazefsky, C.A., Filipink, R., Lindsey, J., & Lubetsky, M.J. (2011). Medical evaluation and comorbid psychiatric disorders. In Autism spectrum disorder (pp. 41–84). New York: Oxford University Press.
  • Mazefsky, C.A., Folstein, S.E., & Lainhart, J.E. (2008). Overrepresentation of mood and anxiety disorders in adults with autism and their first-degree relatives: What does it mean?. Autism Research: Official Journal of the International Society for Autism Research, 1, 193–197. doi:10.1002/aur.23
  • Mazefsky, C.A., Herrington, J., Siegel, M., Scarpa, A., Maddox, B.B., Scahill, L., & White, S.W. (2013). The role of emotion regulation in autism spectrum disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 52, 679–688. doi:10.1016/j.jaac.2013.05.006
  • Mazefsky, C.A., Oswald, D.P., Day, T.N., Eack, S.M., Minshew, N.J., & Lainhart, J.E. (2012). ASD, a psychiatric disorder, or both? Psychiatric diagnoses in adolescents with high-functioning ASD. Journal of Clinical Child & Adolescent Psychology, 41, 516–523. doi:10.1080/15374416.2012.686102
  • Mazefsky, C.A., & White, S.W. (2014). Emotion regulation: Concepts & practice in autism spectrum disorder. Child and Adolescent Psychiatric Clinics of North America, 23, 15–24. doi:10.1016/j.chc.2013.07.002
  • Mazurek, M.O. (2014). Loneliness, friendship, and well-being in adults with autism spectrum disorders. Autism, 18, 223–232. doi:10.1177/1362361312474121
  • McGuire, K., Fung, L.K., Hagopian, L., Vasa, R.A., Mahajan, R., Bernal, P., … Whitaker, A.H. (2016). Irritability and problem behavior in autism spectrum disorder: A practice pathway for pediatric primary care. Pediatrics, 137(Supplement), S136–S148. doi:10.1542/peds.2015-2851L
  • Merikangas, K., Jian-Ping, H., Burstein, M., Swanson, S., Avenevoli, S., Lihong, C., … Swendsen, J. (2011). Lifetime prevalence of mental disorders in US adolescents: Results from the national comorbidity study-adolescent supplement. Journal of the American Academy Children Adolescent Psychiatry, 49, 980–989. doi:10.1016/j.jaac.2010.05.017.Lifetime
  • Miodovnik, A., Harstad, E., Sideridis, G., & Huntington, N. (2015). Timing of the diagnosis of attention-deficit/hyperactivity disorder and autism spectrum disorder. Pediatrics, 136, e830–e837. doi:10.1542/peds.2015-1502
  • Morrison, K.E., Pinkham, A.E., Penn, D.L., Kelsven, S., Ludwig, K., & Sasson, N.J. (2017). Distinct profiles of social skill in adults with autism spectrum disorder and schizophrenia. Autism Research, 10, 878–887. doi:10.1002/aur.1734
  • Moskowitz, L.J., Rosen, T.E., Lerner, M.D., & Levine, K. (2016). Assessment of anxiety in youth with autism spectrum disorder. In Evidence based assessment and treatment of anxiety in children and adolescents with autism spectrum disorder. London: Elsevier. Retrieved from https://www.sciencedirect.com/science/article/pii/B9780128051221000144
  • Newschaffer, C., Croen, L.A., Daniels, J., Giarelli, E., Grether, J.K., Levy, S.E., … Windham, G.C. (2007). The epidemiology of autism spectrum disorders. Annual Review of Public Health, 28, 235–258. doi:10.1146/annurev.publhealth.28.021406.144007
  • Norris, M., & Lecavalier, L. (2010). Screening accuracy of Level 2 autism spectrum disorder rating scales. A review of selected instruments. Autism: The International Journal of Research and Practice, 14, 263–284. doi:10.1177/1362361309348071
  • Owen, M.J., O’donovan, M.C., Thapar, A., & Craddock, N. (2011). Neurodevelopmental hypothesis of schizophrenia. British Journal of Psychiatry, 198, 173–175. doi:10.1192/bjp.bp.110.084384
  • Ozonoff, S., Pennington, B.F., & Rogers, S.J. (1991). Executive function deficits in high functioning autistic individuals: relationship to theory of mind. Journal of Child Psychology and Psychiatry, 32, 1081–1106. doi:10.1111/j.1469-7610.1991.tb00351.x
  • Pine, D.S., Guyer, A.E., Goldwin, M., Towbin, K.A., & Leibenluft, E. (2008). Autism spectrum disorder scale scores in pediatric mood and anxiety disorders. Journal of the American Academy of Child & Adolescent Psychiatry, 47, 652–661. doi:10.1097/CHI.0b013e-31816bffa5
  • Pinkham, A.E., Sasson, N.J., Beaton, D., Abdi, H., Kohler, C.G., & Penn, D.L. (2012). Qualitatively distinct factors contribute to elevated rates of paranoia in autism and schizophrenia. Journal of Abnormal Psychology, 121, 767–777. doi:10.1037/a0028510
  • Rao, P.A., & Landa, R.J. (2014). Association between severity of behavioral phenotype and comorbid attention deficit hyperactivity disorder symptoms in children with autism spectrum disorders. Autism, 18, 272–280. doi:10.1177/1362361312470494
  • Rapoport, J., Chavez, A., Greenstein, D., Addington, A., & Gogtay, N. (2009). Autism-spectrum disorders and childhood onset schizophrenia: Clinical and biological contributions to a relationship revisited. The Journal of Child Psychology and Psychiatry and Allied Disciplines, 48, 10–18. doi:10.1097/CHI.0b013e31818b1c63.Autism-Spectrum
  • Reichow, B., Volkmar, F.R., & Bloch, M.H. (2013). Systematic review and meta-analysis of pharmacological treatment of the symptoms of attention-deficit/hyperactivity disorder in children with pervasive developmental disorders. Journal of Autism and Developmental Disorders, 43, 2435–2441. doi:10.1007/s10803-013-1793-z
  • Reiersen, A.M., Constantino, J.N., & Richard, T.D. (2008). Co-occurrence of motor problems and autistic symptoms in attention-deficit/hyperactivity disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 47, 662–672. doi:10.1097/CHI.0b013e31816bff88
  • Reiersen, A.M., & Todd, R.D. (2008). Co-occurrence of ADHD and autism spectrum disorders: Phenomenology and treatment. Expert Review of Neurotherapeutics, 8, 657–669. doi:10.1586/14737175.8.4.657
  • Reiss, S., Levitan, G.W., & Szyszko, J. (1982). Emotional disturbance and mental retardation: Diagnostic overshadowing. American Journal of Mental Deficiency, 86, 567–574.
  • Research Units on Paediatric Psychopharmacology (RUPP) Autism Network. (2005). Randomized, controlled, crossover trial of methylphenidate in pervasive developmental disorders with hyperactivity. Archives of General Psychiatry, 62, 1266–1274. doi:10.1001/archpsyc.62.11.1266
  • Righi, G., Benevides, J., Mazefsky, C., Siegel, M., Sheinkopf, S.J., Morrow, E.M., … Lubetsky, M. (2017). Predictors of inpatient psychiatric hospitalization for children and adolescents with autism spectrum disorder. Journal of Autism and Developmental Disorders, 1–11. doi:10.1007/s10803-017-3154-9
  • Rodriguez-Seijas, C., Gadow, K., Rosen, T., Kim, H., Lerner, M., & Eaton, N.R. (under review). Transdiagnostic Psychiatric Comorbidity and Autism Spectrum Disorder. Manuscript in preparation.
  • Rommelse, N.N.J., Franke, B., Geurts, H.M., Hartman, C.A., & Buitelaar, J.K. (2010). Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder. European Child and Adolescent Psychiatry, 19, 281–295. doi:10.1007/s00787-010-0092-x
  • Ronald, A., Larsson, H., Anckarsäter, H., & Lichtenstein, P. (2014). Symptoms of autism and ADHD: A Swedish twin study examining their overlap. Journal of Abnormal Psychology, 123, 440–451. doi:10.1037/a0036088
  • Rosen, T.E., Connell, J.E., & Kerns, C.M. (2016). A review of behavioral interventions for anxiety-related behaviors in lower-functioning individuals with autism. Behavioral Interventions, 31, 120–143. doi:10.1002/bin.1442
  • Rosen, T.E., & Lerner, M.D. (2016). Externalizing and internalizing symptoms moderate longitudinal patterns of facial emotion recognition in autism spectrum disorder. Journal of Autism and Developmental Disorders, 46, 2621–2634. doi:10.1007/s10803-016-2800-y
  • Russell, G., Rodgers, L.R., & Ford, T. (2013). The strengths and difficulties questionnaire as a predictor of parent-reported diagnosis of autism spectrum disorder and attention deficit hyperactivity disorder. PLoS ONE, 8, e80247. doi:10.1371/journal.pone.0080247
  • Rutter, M. (1970). Autistic children: infancy to adulthood. Semin Psychiatry, 2, 435–450.
  • Saha, S., Chant, D., Welham, J., & McGrath, J. (2005). A systematic review of the prevalence of schizophrenia. PLoS Medicine, 2, 0413–0433. doi:10.1371/journal.pmed.0020141
  • Santosh, P.J., & Mijovic, A. (2006). Does pervasive developmental disorder protect children and adolescents against drug and alcohol use?. European Child & Adolescent Psychiatry, 15, 183–188. doi:10.1007/s00787-005-0517-0
  • Sasson, N.J., Pinkham, A.E., Weittenhiller, L.P., Faso, D.J., & Simpson, C. (2016). Context effects on facial affect recognition in schizophrenia and autism: Behavioral and eye-tracking evidence. Schizophrenia Bulletin, 42, 675–683. doi:10.1093/schbul/sbv176
  • Seidman, L.J. (2006). Neuropsychological functioning in people with ADHD across the lifespan. Clinical Psychology Review, 26, 466–485. doi:10.1016/j.cpr.2006.01.004
  • Silverman, W.K., & Albano, A.M. (1996). The anxiety disorders interview schedule for children (ADIS-C/P). San Antonio, TX: Psychological Corporation.
  • Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 921–929. doi:10.1097/CHI.0b013e318-179964f
  • Skokauskas, N., & Frodl, T. (2015). Overlap between autism spectrum disorder and bipolar affective disorder. Psychopathology, 48, 209–216. doi:10.1159/000435787
  • Spek, A. A., van Ham, N.C., & Nyklíček, I. (2013). Mindfulness-based therapy in adults with an autism spectrum disorder: A randomized controlled trial. Research in Developmental Disabilities, 34, 246–253. doi:10.1016/j.ridd.2012.08.009
  • Sprenger, L., Bühler, E., Poustka, L., Bach, C., Heinzel-Gutenbrunner, M., Kamp-Becker, I., & Bachmann, C. (2013). Impact of ADHD symptoms on autism spectrum disorder symptom severity. Research in Developmental Disabilities, 34, 3545–3552. doi:10.1016/j.ridd.2013.07.028
  • Starling, J., & Dossetor, D. (2009). Pervasive developmental disorders and psychosis. Current Psychiatry Reports, 11, 190–196. doi:10.1007/s11920-009-0030-0
  • Stewart, M.E., Barnard, L., Pearson, J., Hasan, R., & O’brien, G. (2006). Presentation of depression in autism and Asperger syndrome: A review. Autism, 10, 103–116. doi:10.1177/1362361306062013
  • Storch, E.A., Abramowitz, J., & Goodman, W.K. (2008). Where does obsessive-compulsive disorder belong in DSM-V?. Depression and Anxiety, 25, 336–347. doi:10.1002/da.20488
  • Storch, E.A., Sulkowski, M.L., Nadeau, J., Lewin, A.B., Arnold, E.B., Mutch, P.J., … Murphy, T.K. (2013). The phenomenology and clinical correlates of suicidal thoughts and behaviors in youth with autism spectrum disorders. Journal of Autism and Developmental Disorders, 43, 2450–2459. doi:10.1007/s10803-013-1795-x
  • Strang, J.F., Meagher, H., Kenworthy, L., de Vries, A.L.C., Menvielle, E., Leibowitz, S., … Anthony, L.G. (2016). Initial clinical guidelines for co-occurring autism spectrum disorder and gender dysphoria or incongruence in adolescents. Journal of Clinical Child and Adolescent Psychology, 4416, 1–11. doi:10.1080/15374416.2016.1228462
  • Sukhodolsky, D.G., Bloch, M.H., Panza, K.E., & Reichow, B. (2013). Cognitive-behavioral therapy for anxiety in children with high-functioning autism: A meta-analysis. Pediatrics, 132, 1341–1350. doi:10.1542/peds.2013-1193
  • Sukhodolsky, D.G., Scahill, L., Gadow, K.D., Arnold, L.E., Aman, M.G., McDougle, C.J., … Vitiello, B. (2008). Parent-rated anxiety symptoms in children with pervasive developmental disorders: Frequency and association with core autism symptoms and cognitive functioning. Journal of Abnormal Child Psychology, 36, 117–128. doi:10.1007/s10802-007-9165-9
  • Supekar, K., Iyer, T., & Menon, V. (2017). The influence of sex and age on prevalence rates of comorbid conditions in autism. Autism Research, 10, 778–789. doi:10.1002/aur.1741
  • Taylor, J.L., & Gotham, K.O. (2016). Cumulative life events, traumatic experiences, and psychiatric symptomatology in transition-aged youth with autism spectrum disorder. Journal of Neurodevelopmental Disorders, 8, 28. doi:10.1186/s11689-016-9160-y
  • Turygin, N.C., Matson, J.L., MacMillan, K., & Konst, M. (2013). The relationship between challenging behavior and symptoms of depression in intellectually disabled adults with and without autism spectrum disorders. Journal of Developmental and Physical Disabilities, 25, 475–484. doi:10.1007/s10882-012-9321-1
  • Van Der Meer, J.M.J., Oerlemans, A.M., Van Steijn, D.J., Lappenschaar, M.G.A., De Sonneville, L.M.J., Buitelaar, J.K., & Rommelse, N.N.J. (2012). Are autism spectrum disorder and attention-deficit/hyperactivity disorder different manifestations of one overarching disorder? Cognitive and symptom evidence from a clinical and population-based sample. Journal of the American Academy of Child and Adolescent Psychiatry, 51, 1160–1172.e3. doi:10.1016/j.jaac.2012.08.024
  • Van Der Miesen, A.I.R., Hurley, H., & De Vries, A.L.C. (2016). Gender dysphoria and autism spectrum disorder: A narrative review. International Review of Psychiatry, 28, 70–80. doi:10.3109/09540261.2015.1111199
  • van der Werf, M., Hanssen, M., Köhler, S., Verkaaik, M., Verhey, F.R., van Winkel, R., … Allardyce, J. (2014). Systematic review and collaborative recalculation of 133,693 incident cases of schizophrenia. Psychological Medicine, 44, 9–16. doi:10.1017/S0033291712002796
  • van Steensel, F.J.A., Bögels, S.M., & de Bruin, E.I. (2013). Psychiatric comorbidity in children with autism spectrum disorders: A comparison with children with ADHD. Journal of Child and Family Studies, 22, 368–376. doi:10.1007/s10826-012-9587-z
  • van Steensel, F.J.A., Bögels, S.M., & Perrin, S. (2011). Anxiety disorders in children and adolescents with autistic spectrum disorders: A meta-analysis. Clinical Child and Family Psychology Review, 14, 302–317. doi:10.1007/s10567-011-0097-0
  • Vannucchi, G., Masi, G., Toni, C., Dell’osso, L., Erfurth, A., & Perugi, G. (2014). Bipolar disorder in adults with Asperger’s Syndrome: A systematic review. Journal of Affective Disorders, 168, 151–160. doi:10.1016/j.jad.2014.06.042
  • Vasa, R.A., Carroll, L.M., Nozzolillo, A.A., Mahajan, R., Mazurek, M.O., Bennett, A.E., … Bernal, M.P. (2014). A systematic review of treatments for anxiety in youth with Autism Spectrum Disorders. Journal of Autism and Developmental Disorders, 44, 3215–3229. doi:10.1007/s10803-014-2184-9
  • Vasa, R.A., Mazurek, M.O., Mahajan, R., Bennett, A.E., Bernal, M.P., Nozzolillo, A.A., … Coury, D.L. (2016). Assessment and treatment of anxiety in youth with autism spectrum disorders. Pediatrics, 137(Supplement), S115–S123. doi:10.1542/peds.2015-2851J
  • Visser, S.N., Danielson, M.L., Bitsko, R.H., Holbrook, J.R., Kogan, M.D., Ghandour, R.M., … Blumberg, S.J. (2014). Trends in the parent-report of health care provider-diagnosed and medicated attention-deficit/hyperactivity disorder: United States, 2003-2011. Journal of the American Academy of Child and Adolescent Psychiatry, 53, 34–46.e2. doi:10.1016/j.jaac.2013.09.001
  • Weisbrot, D., Gadow, K., DeVincent, C., & Pomeroy, J. (2005). The presentation of anxiety in children with pervasive developmental disorders. Journal of Child and Adolescent Psychopharmacology, 15, 477–496. doi:10.1089/cap.2005.15.477
  • Weiss, J.A. (2014). Transdiagnostic case conceptualization of emotional problems in youth with ASD: An emotion regulation approach. Clinical Psycholoogy: Science and Practice, 21, 331–350. doi:10.1111/cpsp.12084
  • Wentz Nilsson, E., Gillberg, C., Gillberg, C., & Rastam, M. (1999). Ten-year follow-up of adolescent-onset anorexia nervosa: Personality disorders. Journal of the American Academy of Child & Adolescent Psychiatry, 38, 1389–1395. doi:10.1097/00004583-199911000-00013
  • Weston, L., Hodgekins, J., & Langdon, P.E. (2016). Effectiveness of cognitive behavioural therapy with people who have autistic spectrum disorders: A systematic review and meta-analysis. Clinical Psychology Review, 49, 41–54. doi:10.1016/j.cpr.2016.08.001
  • Westwood, H., & Tchanturia, K. (2017). Autism spectrum disorder in anorexia nervosa: An updated literature review. Current Psychiatry Reports, 19, 41. doi:10.1007/s11920-017-0791-9
  • White, S.W., Lerner, M.D., McLeod, B.D., Wood, J.J., Ginsburg, G.S., Kerns, C., … Compton, S. (2015). Anxiety in youth with and without autism spectrum disorder: Examination of factorial equivalence. Behavior Therapy, 46, 40–53. doi:10.1016/j.beth.2014.05.005
  • Witwer, A.N., & Lecavalier, L. (2010). Validity of comorbid psychiatric disorders in youngsters with autism spectrum disorders. Journal of Developmental and Physical Disabilities, 22, 367–380. doi:10.1007/s10882-010-9194-0
  • Wood, J.J., & Gadow, K.D. (2010). Exploring the nature and function of anxiety in youth with autism spectrum disorders. Clinical Psychology: Science and Practice, 17, 281–292. doi:10.1111/j.1468-2850.2010.01220.x
  • Wozniak, J., Biederman, J., Faraone, S.V., Frazier, J., Kim, J., Millstein, R., … Snyder, J.B. (1997). Mania in children with pervasive developmental disorder revisited. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 1552–1559-1560. doi:10.1016/S0890-8567(09)66564-3

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