Advanced search
Publication Cover
Journal of Dermatological Treatment Volume 15, 2004 - Issue 4
Submit an article Journal homepage
90
Views
8
CrossRef citations to date
0
Altmetric
Article

Combination therapy consisting of week pulses of oral terbinafine plus topical application of terbinafine cream in the treatment of onychomycosis

B Sanmano Department of Dermatology, Juntendo University School of Medicine, Tokyo, Japan
,
M Hiruma Department of Dermatology, Juntendo University School of Medicine, Tokyo, Japan
,
M Mizoguchi Department of Dermatology, Juntendo University School of Medicine, Tokyo, Japan
&
H Ogawa Department of Dermatology, Juntendo University School of Medicine, Tokyo, JapanCorrespondence[email protected] [email protected]
Pages 245-251 | Received 26 Jan 2004, Accepted 22 Apr 2004, Published online: 12 Jul 2009

References

  • Kejda J, Itraconazole pulse therapy vs continuous terbinafine dosing for toenail onychomycosis. Postgrad Med 1999; Spec No: 12–15.
  • Harrell TK, Necomb WW, Replogle WH et al, Onycho- mycosis: improved cure rates with itraconazole and terbinafine. J Am Board Fam Pract (2000) 13: 268–73.
  • Hiruma M, Matsushita A, Kobayashi M et al, One week pulse therapy with itraconazole (200 mg day-1) for onychomycosis. Evaluation of treatment results accord- ing to patient background. Mycoses (2001) 44: 87–93.
  • Gupta AK, Lynde CW, Konnikov N, Single-blind, randomized, prospective study of sequential itraconazole and terbinafine pulse compared with terbinafine pulse for the treatment of toenail onychomycosis. J Am Acad Dermatol (2001) 44: 485–91.
  • Jain S, Sehgal VN, Itraconazole versus terbinafine in the management of onychomycosis: an overview. J Dermatol Treat (2003) 14: 30–42.
  • Faergemann J, Zehender H, Denouel J et al, Levels of terbinafine in plasma, stratum corneum, dermis- epidermis (without stratum corneum), sebum, hair and nails during and after 250 mg terbinafine orally once per day for four weeks. Acta Derm Venereol (1993) 73: 305–9.
  • Debruyne D, Coquerel A, Pharmacokinetics of antifungal agents in onychomycoses. Clin Pharmacokinet (2001) 40: 441–72.
  • Heikkila H, Stubb S, Long-term results in patients with onychomycosis treated with terbinafine or itraconazole. Br J Dermatol (2002) 146: 250–3.
  • Tosti A, Piraccini BM, Stinchi C et al, Treatment of dermatophyte nail infections: an open randomized study comparing intermittent terbinafine therapy with con- tinuous terbinafine treatment and intermittent itraco- nazole therapy. J Am Acad Dermatol (1996) 34: 595–600.
  • Alpsoy E, Yilmaz E, Basaran E, Intermittent therapy with terbinafine for dermatophyte toe-onychomycosis: a new approach. J Dermatol (1996) 23: 259–62.
  • Warshaw EM, Carver SM, Zielke GR et al, Intermittent terbinafine for toenail onychomycosis: is it effective? Results of a randomized pilot trial. Arch Dermatol (2001) 137: 1253.
  • Darkes MJ, Scott LJ, Goa KL, Terbinafine: a review of its use in onychomycosis in adults. Am J Clin Dermatol (2003) 4: 39–65.
  • Scher RK, Onychomycosis: therapeutic update. J Am Acad Dermatol (1999) 40: S21–6.
  • Gupta AK, Adam P, Terbinafine pulse therapy is effective in tinea capitis. Pediatr Dermatol (1998) 15: 56–8.
  • Albanese G, Di Cintio R, Martini C, Nicoletti A, Short therapy for tinea unguium with terbinafine: four differ- ent courses of treatment. Mycoses (1995) 38: 211–14.
  • Gupta AK, Ryder J, Summerbell RC, Comparison of efficacy criteria across onychomycosis trials: need for standardization. Int J Dermatol (2003) 42: 312–15.
  • Evans EG, Drug synergies and the potential for combination therapy in onychomycosis. Br J Dermatol (2003) 149 (suppl 65): 11–13.
  • Olafsson JH, Sigurgeirsson B, Baran R, Combination therapy for onychomycosis. Br J Dermatol (2003) 149 (suppl 65): 15–18.
  • Rigopoulos D, Katoulis AC, Ioannides D et al, A randomized trial of amorolfine 5% solution nail lacquer in association with itraconazole pulse therapy compared with itraconazole alone in the treatment of Candida fingernail onychomycosis. Br J Dermatol (2003) 149: 151–6.
  • Evans EG, The rationale for combination therapy. Br J Dermatol (2001) 145 (suppl 60): 9–13.
  • Baran R, Topical amorolfine for 15 months combined with 12 weeks of oral terbinafine, a cost-effective treatment for onychomycosis. Br J Dermatol (2001) 145 (suppl 60): 15–19.
  • Lecha M, Amorolfine and itraconazole combination for severe toenail onychomycosis; results of an open randomized trial in Spain. Br J Dermatol (2001) 145 (suppl 60): 21–6.
  • Baran R, Feuilhade M, Combernale P et al, A randomized trial of amorolfine 5% solution nail lacquer combined with oral terbinafine compared with terbina- fine alone in the treatment of dermatophytic toenail onychomycoses affecting the matrix region. Br J Dermatol (2000) 142: 1177–83.
  • Reinel D, Clarke C, Comparative efficacy and safety of amorolfine nail lacquer 5% in onychomycosis, once- weekly versus twice-weekly. Clin Exp Dermatol (1992) 17 (suppl 1): 44–9.
  • Gupta AK, Ryder JE, Baran R, The use of topical therapies to treat onychomycosis. Dermatol Clin (2003) 21: 481–9.
  • Faergemann J, Baran R, Epidemiology, clinical presenta- tion and diagnosis of onychomycosis. Br J Dermatol (2003) 149 (suppl 65): 1–4.
  • Scher RK, Baran R, Onychomycosis in clinical practice: factors contributing to recurrence. Br J Dermatol (2003) 149 (suppl 65): 5–9.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.