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Journal of Dermatological Treatment Volume 35, 2024 - Issue 1
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Research Article

A multicenter, double-blind, randomized, parallel-group, active-controlled, phase 3 clinical trial to compare the effectiveness and safety of two botulinum toxin type A formulations for improving moderate to severe glabellar wrinkles in Asians

Sun Young Choia Department of Dermatology, Chung-Ang University Gwangmyeong Hospital, Chung-Ang University College of Medicine, Gwangmyeong-si, Gyeonggi-do, Republic of KoreaORCID Iconhttps://orcid.org/0000-0003-0248-7708View further author information
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Young Gue Kohb Department of Dermatology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Republic of KoreaORCID Iconhttps://orcid.org/0000-0002-6376-0328View further author information
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Yang Won Leec Department of Dermatology, Konkuk University School of Medicine, Seoul, Republic of Korea;d Research Institute of Medical Science, Konkuk University, Seoul, Republic of KoreaORCID Iconhttps://orcid.org/0000-0003-1268-1248View further author information
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Hyung Seok Sonc Department of Dermatology, Konkuk University School of Medicine, Seoul, Republic of KoreaORCID Iconhttps://orcid.org/0000-0002-0607-7530View further author information
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Yi Na Yoonc Department of Dermatology, Konkuk University School of Medicine, Seoul, Republic of KoreaORCID Iconhttps://orcid.org/0000-0001-8050-1750View further author information
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Gyeonghoon Kime Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of KoreaORCID Iconhttps://orcid.org/0000-0002-5350-2309View further author information
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Chonghyun Wone Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of KoreaORCID Iconhttps://orcid.org/0000-0003-1997-2240View further author information
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Hyesoo Choe Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of KoreaORCID Iconhttps://orcid.org/0000-0002-5284-2037View further author information
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Joo-Sun Sonf R&D Center, BMI KoreaORCID Iconhttps://orcid.org/0009-0004-4311-4072View further author information
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Eun-Kyoung Kimf R&D Center, BMI KoreaORCID Iconhttps://orcid.org/0009-0005-2700-3273View further author information
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Beom Joon Kimb Department of Dermatology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Republic of KoreaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-2320-7621View further author information
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Article: 2359511 | Received 07 Dec 2023, Accepted 23 Apr 2024, Published online: 16 Jun 2024

References

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  • Rzany BJ, Ascher B, Avelar RL, et al. A multicenter, randomized, double-blind, placebo-controlled, single-dose, phase III, non-inferiority study comparing PrabotulinumtoxinA and OnabotulinumtoxinA for the treatment of moderate to severe glabellar lines in adult patients. Aesthet Surg J. 2020;40(4):413–429.
  • Monheit GD, Cohen JL; Reloxin Investigational Group. Long-term safety of repeated administrations of a new formulation of botulinum toxin type a in the treatment of glabellar lines: interim analysis from an open-label extension study. J Am Acad Dermatol. 2009;61:421–425.

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