38
Views
28
CrossRef citations to date
0
Altmetric
Research Article

Dose–response of initial G2-chromatid breaks induced in normal human fibroblasts by heavy ions

, , , , , & show all
Pages 165-174 | Published online: 03 Jul 2009

References

  • ALSBEIH, G. and RAAPHORST, G. P., 1999, Differential induction of premature chromosome condensation by calyculin A in human fibroblast and tumor cell lines. Anticancer Research, 19, 903–908.
  • BARENDSEN, G. W., 1968, Responses of cultured cells, tumours and normal tissues to radiations of different linear energy transfer. In: Current Topics of Radiation Research, vol. IV, edited by M. Ebert and A. Howard (Amsterdam: North-Holland), pp. 293–356.
  • BEDFORD, J. S. and GOODHEAD, D. T., 1989, Breakage of human interphase chromosomes by alpha particles and X-rays. International Journal of Radiation Biology, 55, 211–216.
  • BOOTSMA, D., BUDKE, L. and Vos, 0., 1964, Studies on synchron-ized division of tissue culture cells initiated by excess thymidine. Experimental Cell Research, 33, 301–304.
  • CORNFORTH, M. N. and BEDFORD, J. S., 1983, X-ray-induced breakage and rejoining of human interphase chromo-somes. Science, 222, 1141–1143.
  • CORNFORTH, M. N. and BEDFORD, J. S., 1993, Ionizing radiation damage and its early development in chromosomes. Advances in Radiation Biology, 17, 423–497.
  • Cox, R. and MAssoN, W. K., 1979, Mutation and inactivation of cultured mammalian cells exposed to beams of acceler-ated heavy ions. III. Human diploid fibroblasts. International Journal of Radiation Biology, 36, 149–160.
  • Cox, R., THACKER, J., GOODHEAD, D. T. and MUNSON, R. J., 1977, Mutation and inactivation of mammalian cells by various ionising radiations. Nature, 267, 425–427.
  • DURANTE, M., FURUSAWA, Y., GEORGE, K., GIALANELLA, G., GRECO, 0., GROSSI, G., MATSUFUJI, N., PUGLIESE, M. and YANG, T. C., 1998a, Rejoining and misrejoining of radiation-induced chromatin breaks. IV. Charged par-ticles. Radiation Research, 149, 446–454.
  • DURANTE, M., FURUSAWA, Y. and GOTOH, E., 1998b, A simple method for simultaneous interphase-metaphase chromo-some analysis in biodosimetry. International Journal of Radiation Biology, 74, 457–462.
  • DURANTE, M., GIALANELLA, G., GROSSI, G. F., NAPPO, M., PUGLIESE, M., BETTEGA, D., CALZOLARI, P., CHIORDA, G. N., 0 TTOLENGHI, A. and TALLONE-LOMBARDI, L., 1994, Radiation-induced chromosomal aberrations in mouse 1011/2 cells: dependence on the cell-cycle stage at the time of irradiation. International Journal of Radiation Biology, 65, 437–447.
  • FURUSAWA, Y., FUKUTSU, K., AOKI, M., ITSUKAICHI, H., EGUCHI-KASAI, K., OHARA, H., YATAGAI, F., KANAI, T. and ANDO, K., 2000, Inactivation of aerobic and hypoxic cells from three different cell lines by accelerated 'He-, 12C-and 20Ne-ion beams. Radiation Research, 154, 485–496.
  • GOODWIN, E. H., BAILEY, S. M., CHEN, D. J. and CORNFORTH, M. N., 1996, The effect of track structure on cell inactiva-tion and chromosome damage at a constant LET of 120keV/pm. Advances in Space Research, 18, 93–98.
  • GOODWIN, E. H., BLAKELY, E. A. and TOBIAS, C. A., 1994, Chromosomal damage and repair in Gl-phase Chinese hamster ovary cells exposed to charged-particle beams. Radiation Research, 138, 343–351.
  • GOTOH, E., ASAKAWA, Y. and KOSAKA, H., 1995, Inhibition of protein serine/threonine phosphatases directly induces premature chromosome condensation in mammalian somatic cells. Biomedical Research, 16, 63–68.
  • GOTOH, E., KAWATA, T. and DURANTE, M., 1999, Chromatid break rejoining and exchange aberration formation fol-lowing y-ray exposure: analysis in G2 human fibroblasts by chemical-induced premature chromosome condensa-tion. International Journal of Radiation Biology, 75, 1129–1135.
  • GRIFFIN, C. S., HARVEY, A. N. and SAVAGE, J. R. K., 1994, Chromatid damage induced by 238Pu a-particles in G2 and S phase Chinese hamster V79 cells. International Journal of Radiation Biology, 66, 85–98.
  • HEI, T. K., CHEN, D. J., BRENNER, D. J. and HALL, E. J., 1988, Mutation induction by charged particles of defined linear energy transfer. Carcinogenesis, 9, 1233–1236.
  • HEINrz, N., SivE, H. L. and ROEDER, R. G., 1983, Regulation of human histone gene expression: kinetics of accumula-tion and changes in the rate of synthesis and half-lives of individual histone mRNAs during the HeLa cell cycle. Molecular Cell Biology, 3, 539–550.
  • HIEBER, L. and LUcKE-HuiLE, C., 1983, PCC technique reveals severe chromatin lesions and repair in G2-arrested cells after alpha irradiation. Experimental Cell Research, 144, 57–62.
  • HITTELMAN, W. N. and RAO, P. N., 1974, Premature chromo-some condensation. I. Visualization of x-ray-induced chromosome damage in interphase cells. Mutation Research, 23, 251–258.
  • JA0a4AN, J. and O'CONNOR, P. M., 1998, Methods for synchron-izing cells at specific stages of the cell cycle. In: Current Protocols in Cell Biology, edited by J. S. Bonifacino, M. Dasso, J. B. Harford, J. Lippincott-Schwartz and K. M. Yamada (Chichester: John Wiley), Unit 8.3.1–8.3.20.
  • JOHNSON, R. T. and RAO, P. N., 1970, Mammalian cell fusion: induction of premature chromosome condensation in interphase nuclei. Nature, 226, 717–722.
  • KAWATA, T., GOTOH, E., DURANTE, M., Wu, H., GEORGE, K., FURUSAWA, Y. and CUCINOTTA, F. A., 2000, High-LET radiation-induced aberrations in prematurely condensed G2 chromosomes of human fibroblasts. International Journal of Radiation Biology, 76, 929–938.
  • KRANERT, T., SCHNEIDER, E. and KIEFER, J., 1990, Mutation induction in V79 Chinese hamster cells by very heavy ions. International Journal of Radiation Biology, 58, 975–987.
  • LOUCAS, B. D. and GEARD, C. R., 1994, Initial damage in human interphase chromosomes from alpha particles with linear energy transfers relevant to radon exposure. Radiation Research, 139, 9–14.
  • MURRAY, A. and HUN TT., 1993, The Cell Cycle: An Introduction (New York: W. H. Freeman and Company).
  • NAPOLITANO, M., DURANTE, M., GROSSI, G. F., PUGLIESE, M. and GIALANELLA, G., 1992, Inactivation of C3H 10T1/2 cells by monoenergetic high LET alpha-particles. International Journal of Radiation Biology, 61, 813–820.
  • PANTELIAS, G. E. and MAILLIE, H. D., 1984, The use of peripheral blood mononuclear cell prematurely con-densed chromosomes for biological dosimetry. Radiation Research, 99, 140–150.
  • RAJU, M. R., EISEN, Y., CARPENTER, S. and INKRET, W. C., 1991, Radiobiology of alpha particles. III. Cell inactiva-tion by alpha-particle traversals of the cell nucleus. Radiation Research, 128, 204–209.
  • SAVAGE, J. R. K., 1975, Classification and relationships of induced chromosomal structural changes. Journal of Medical Genetics, 13, 103–122.
  • STEIN, G. S. and BORUN, T. W., 1972, The synthesis of acidic chromosomal proteins during the cell cycle of HeLa cells. Journal of Cell Biology, 52, 292–296.
  • SUZUKI, M., WATANABE, M., SUZUKI, K., NAKANO, K. and KANEKO, I., 1989, Neoplastic cell transformation by heavy ions. Radiation Research, 120, 468–476.
  • THACKER, J., STRETCH, A. and STEVENS, M. A., 1979, Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. II. Chinese hamster V79 cells. International Journal of Radiation Biology, 36, 137–148.
  • TSUBOI, K., YANG, T. C. and CHEN, D. J., 1992, Charged-particle mutagenesis. 1. Cytotoxic and mutagenic effects of high-LET charged iron particles on human skin fibroblasts. Radiation Research, 129, 171–176.
  • WALDREN, C. A. and JoHNsoN, R. T., 1974, Analysis of interphase chromosome damage by means of premature chromo-some condensation after X- and ultraviolet-irradiation. Proceedings of the National Academy of Sciences of the United States of America, 71, 1137–1141.
  • WATANABE, M., SUZUKI, M., SUZUKI, K., NAKANO, K. and YATAGAI, F., 1992, Radiation-induced chromosome damage in GI phase cells as breaks in premature chromo-some condensation (PCC) and its biological meaning. Journal of Radiation Research, 33, 87–94.
  • YANG, T. C., CRAISE, L. M., MET, M. and TOBIAS, C. A., 1985, Neoplastic cell transformation by heavy charged particles. Radiation Research, 8, (Suppl.), S177—S187.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.