21
Views
4
CrossRef citations to date
0
Altmetric
Article

Persistence of altered 5‐hydroxytryptamine turnover following hemibody X‐irradiation in the rat distal colon

, , &
Pages 399-411 | Received 27 Feb 2003, Accepted 22 Mar 2004, Published online: 03 Jul 2009

References

  • AHONEN, A., KYOSOLA, K. and PENTriTA, 0., 1976, Entero-chromaffin cells in macrophages in ulcerative colitis and irritable colon. Annals of Clinical Research, 8, 1–7.
  • BRADFORD, M. M., 1976, A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein—dye binding. Analytica Biochemistry, 72, 248–254.
  • BUELL, M. G. and HARDING, R. K., 1989, Proinflammatory effects of local abdominal irradiation on rat gastrointestinal tract. Digestive Diseases and Sciences, 34, 390–399.
  • CARR, K. E., 2001, Effects of radiation damage on intestinal morphology. International Review of Cytology, 208, 1–119.
  • CARR, K. E., HUME, S. P., NELSON, A. C., O'SHEA, 0., HAZZARD, R. A. and McCuTTouGH, J. S., 1996, Morphological profiles of neutron and X-irradiated small intestine. Journal of Radiation Research, 37, 38–48.
  • CHAMPIER, J., CLAUSTRAT, B., BESANCON, R., EYMIN, C., KILLER, C., JOUVET, A., CHAMBA, G. and FEVRE-MONTANGE, M., 1997, Evidence for tryptophan hydroxylase and hydroxy-indo1-0-methyl-transferase mRNAs in human blood platelets. Life Sciences, 60, 2191–2197.
  • CHEN, J. J., Li, Z., PAN, H., MURPHY, D. L., TAMIR, H., KOEPSELL, H. and GERSHON, M. D., 2001, Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: abnormal intestinal motility and the expression of cation transporters. Journal of Neuroscience, 21, 6348–6361.
  • CH, J. X., PAN, H., ROTHMAN, T. P., WE, P. R. and GERSHON, M. D., 1998, Guinea pig 5-HT transporter: cloning, expression, distribution, and function in intestinal sensory reception. American Journal of Physiology, 275, G433—G448.
  • DE BRUINE, A. P., DINJENS, W. N., ZuTEma, J. H., LENDERS, M. H. and BOSMAN, F. T., 1992, Renewal of enterochromaffin cells in the rat caecum. Anatomical Record, 233, 75–82.
  • DOMEK, M.", BLACKMAN, E. I., KkO, J., ZHANG, X. Y., IWATA, F. N., SENO, K. and LEUNG, F. W., 1997, Functional ablation of afferent nerves aggravates dextran sulphate sodium-induced colonic damage in rats. Journal of Gastroenterology and Hepatology, 12, 698–702.
  • DUBLINEAU, I., KSAS, B., AIGUEPERSE, J., GOURMELON, P. and GRIFFITHS, N. M., 1998, In vivo alterations of fluid and electrolyte fluxes in rat colon by gamma irradiation. Digestive Diseases and Sciences, 43, 652–662.
  • DUBLINEAU, I., MOREL, E. and GRIFFITHS, N. M., 2002, Characterization of altered absorptive and secretory functions in the rat colon after abdominal irradiation: comparison with the effects of total-body irradiation. Radiation Research, 157, 52–61.
  • ERSPAMER, V. and ASERO, B., 1952, Identification of enteramine, the specific hormone of the enterochromaffin cell system, as 5-hydroxytryptamine. Nature, 169, 800–801.
  • FRANcOIS, A., KSAS, B., GOURMELON, P. and GRIFFITHS, N. M., 2000, Implication of 5-HT-mediated pathways in radiation-induced attenuation and recovery of rat colonic electrolyte transport. American Journal of Physiology, 278, G75—G82.
  • GERSHON, M. D., 1999, Review article: roles of 5-hydroxytryptamine in the physiology of the bowel. Alimentary Pharmacology and Therapeutics, 13\(Suppl. 2), 15–30.
  • GERSHON, M. D., DREYFUS, C. F., PICKEL, V. M., JOH, T. H. and REIS, D. J., 1977, Serotonergic neurons in the peripheral nervous system: identification in gut by immuno-histochemical localization of tryptophan hyclroxylase. Proceedings of National Academy of Sciences, USA, 74, 3086–3089.
  • GOKE, B., RIGHTER, G., KEIM, V. and ARNOLD, R., 1987, Tryptophan rich diet as a new approach to study the serotoninergic enteropancreatic axis. Gut, 28, 203–205.
  • HIRSCHOWITZ, L. and RODE, J., 1991, Changes in neurons, neuroendocrine cells and nerve fibres in lamina propria of irradiated bowel. Virchows Archly A Pathological Anatomy and Histopathology, 418, 163–168.
  • HORSCHITZ, S., HUMMERICH, R. and SCHLOSS, P., 2001, Structure, function and regulation of the 5-hyclroxytryptamine (serotonin) transporter. Biochemical Society Transactions, 29, 728–732.
  • HUSEBYE, E., SKAR, V., HOVERSTAD, T., IVERSEN, T. and MELBY, K., 1995, Abdominal intestinal motor patterns explain enteric colonization with Gram-negative bacilli in late radiation enteropathy. Gastroenterology, 109, 1078–1089.
  • KACHUR, J. F., KESHAVARZIAN, A., SUNDARESAN, R., DORIA, M., DE LAS ALAS, M. M. and GAGINELLA, T. S., 1995, Colitis reduces short-circuit current response to inflammatory mediators in rat colonic mucosa. Inflammation, 19, 245–259.
  • LAMPERT, I. A., THORPE, P., VAN NORDEN, S., MARSH, J., GOLDMAN, J. M., GORDON-SMITH, E. C. and EVANS, D. J., 1985, Selective sparing of enterochromaffin cells in graft versus host disease affecting the colonic mucosa. Histopathology, 9, 875–886.
  • LINDEN, D. R., CHEN," X., GERSHON, M. D., SHARKEY, K. A. and MAWE, G. M., 2003, Serotonin availability is increased in mucosa of guinea pigs with TNBS-induced colitis. American Journal of Physiology, 285, G207—G216.
  • Lu, S. J., Liu, Y. Q, LIN,J. S., Wu, H. J., SUN, Y. H. and TAN, Y. B, 1999, VIP immunoreactive nerves and somatostatin and serotonin containing cells in Crohn's disease. World Journal of Gastroenterology, 5, 541–543.
  • MACNAUGHTON, W. K. and LEACH, K. E., 1995, Ionising radiation-induced intestinal hypersecretion is region specific and 5-HT3-dependent. Gastroenterology, 108, A303.
  • MACNAUGHTON, W. K., LEACH, K. E., PRUD'HOMME-LALONDE, L., Ho, W. and SHARKEY, K. A., 1994, Ionizing radiation reduces neurally evoked electrolyte transport in rat ileum through a mast cell-dependent mechanism. Gastroentero-logy, 106, 324–335.
  • MAGRO, F., VIEIRA-COELHO, M. A., FRAGA, S., SERRA°, M. P., VELOSO, F. T. and SOARES-DA-SILVA, P., 2002, Impaired synthesis or cellular storage of norepinephrine, dopamine, and 5-hydroxytryptamine in human inflammatory bowel disease. Digestive Diseases and Sciences, 47, 216–224.
  • MCHUOLL, K. J., WEINGARTEN, C., KEENAN, C., WALLACE, J. L. and COLLINS, S. M., 1993, On the suppression of food intake in experimental models of colitis. American Journal of Physiology, 264, R871—R876.
  • MIWA, J., ECHIZEN, H., MATSUEDA, K. and UMEDA, N., 2001, Patients with constipation-predominant irritable bowel syndrome (IBS) may have elevated serotonin concentra-tions in colonic mucosa as compared with diarrhoea-predominant patients and subjects with normal bowel habits. Digestion, 63, 188–194.
  • MOREL, E., DUBL1NEAU, I., LEBRUN, F. and GRIFFITHS, N. M., 2002, Alterations of the VIP-stimulated cAMP pathway in rat distal colon after abdominal irradiation. American Journal of Physiology, 282, G835—G843.
  • NAGIEV, E. and TSYUL'SKII, V. V., 1990, Monoamine oxiclase activity in gastrointestinal tract tissues of animals after irradiation and administration of pyridoxal phosphate. Ukrains'kyi biokhimichnyi zhurnal, 62, 114–118.
  • OSHIMA, S., FUJINIURA, M. and FUKIMIYA, M., 1999, Changes in number of serotonin-containing cells and serotonin levels in the intestinal mucosa of rats with colitis induced by dextran sodium sulfate. Histochemistry and Cell Biology, 112, 257–263.
  • PANES, J., MOLLA, M., CASADEVALL, M., SALAS, A., SANS, M., CONILL, C., ANDERSON, D. C., ROSELLO-CATAFUS, J., GRANGER, D. N. and PIQUE, J. M., 2000, Tepoxalin inhibits inflammation and microvascular dysfunction induced by abdominal irradiation in rats. Alimentary Pharmacology and Therapeutics, 14, 841–850.
  • PARMENTIER, H. K., DE VRIES, C., RUITENBERG, E. J. and VAN LOVERN, H., 1987, Involvement of serotonin in intestinal mastoctyopoiesis and inflammation during a Tfichinella spiralis infection in mice. International Archives of Allergy and Applied Immunology, 83, 31–38.
  • PENTRRI AA., KORMAN°, M. and AHONEN, A., 1975, Effects of 400 R whole-body X-irradiation on 5-hydroxytryptamine content of the rat gastrointestinal tract. Strahlentherapie, 149, 426–437.
  • PICARD, C., KSAS, B., GRIFFITHS, N. M. and FIORAMONTI, J., 2002, Effect of granisetron on radiation-induced alterations of colonic motility and fluid absorption in rats. Alimentary Pharmacology and Therapeutics, 16, 623–631.
  • PICARD, C., WYSOCKI, J., LINARD, C., GARCIA-VILLAR, R., BUENO, L., GRIEErrlls, N. M. and FIORAMONTI, J., 2001, Absence of protective role of afferent nerves in early intestinal mucosal alterations induced by abdominal irradiation in rats. International Journal of Radiation Biology, 77, 349–356.
  • PIETROLETIT, R., BLAAUWGEERS, J. L., TAAT, C. W., SIMI, M., BRUMMELKAMP, W. H. and BECKER, A. E., 1989, Intestinal endocrine cells in radiation enteritis. Surgery, Gynecology and Obstetrics, 169, 127–130.
  • POTREN, C. S., 1990, A comprehensive study of the radio-biological response of the murine (BDF1) small intestine. International Journal of Radiation Biology, 58, 925–973.
  • POTT'EN, C. S., 1995, Structure, function and proliferative organisation of mammalian gut. In C. S. Potten and J. H. Hendry (eds), Radiation and Gut (Amsterdam: Elsevier), pp. 1–31.
  • Qu, Y., MOONS, L. and VANDESANDE, F., 1997, Determination of serotonin, catecholamines and their metabolites by direct injection of supernatants from chicken brain tissue homo-genate using liquid chromatography with electrochemical detection. Journal of Chromatography B, Biomedical Sciences and Applications, 704, 351–358.
  • ROPENGA, A. and GRIFFITHS, N. M., 2001, Persistence of modifications in 5-HT-associated short-circuit current responses in rat distal colon following radiation exposure. Journal of Physiology 533P (abst).
  • SPILLER, R. C., JENKINS, D., THORNLEY, J. P., HEBDEN, J. M., WRIGHT, T., SKINNER, M. and NEAL, K. R., 2000, Increased rectal mucosal enteroendocrine cells, T lymphocytes, and increased gut permeability following acute Campylobacter enteritis and in post-dysenteric irritable bowel syndrome. Gut, 47, 804–811.
  • SPRRZER, T. R., FRIEDMAN, C. J., BUSHNELL, W., FRANKEL, S. R. and RASCHKO, J., 2000, Double-blind, randomized, parallel-group study on the efficacy and safety of oral granisetron and oral onclansetron in the prophylaxis of nausea and vomiting in patients receiving hyperfractionated total body irradiation. Bone Marrow Transplantation, 26, 203–210.
  • TERRY, N. H. A., DENEKAMP, J. and MAUGHAN, R. L., 1983, RBE values and repair characteristics for cob-rectal injury after caesium 137 gamma ray and neutron irradiation. I. Single doses. British Journal of Radiology, 56, 257–265.
  • TSUROUCM, S. and LEBLOND, C. P., 1979, Migration and turnover of entero-endocrine and caveolated cells in the epithelium of the descending colon, as shown by radioautography after continuous infusion of 3H-thymid.ine into mice. American Journal of Anatomy, 156, 431–451.
  • VEN1NGA, T. S., KERKSTRA, J. and WAGENAAR, J., 1973, Origin of radiation released serotonin in rabbits and mice. Acta Radiologica—Therapy, Physics, Biology, 12, 454–464.
  • WADE, P. R., CHEN, J., JAFFE, B., KAssEm, I. S., BLAKELY, R. D. and GERSHON, M. D., 1996, Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract. Journal of Neurosciences, 16, 2352–2364.
  • WALDEN, T. L. and FARZANEH, N. K., 1990, Biological dosimeters. In T. L. Walden and N. K. Farzaneh (eds), Biochemistg of Ionizing Radiation (New York: Raven), pp. 160–175.
  • Yu, P. L., FUJ1MURA, M., OKUMIYA, K., KINOSHITA, M., HASEGAWA, H. and FujariYA, M., 1999, Immunohistochemical localiza-tion of tryptophan hydroxylase in the human and rat gastrointestinal tracts. Journal of Comparative Neurology, 411, 654–665.
  • ZHAO, R., BAIG, M. K., WEXNER, S. D., CHEN, W., SINGH, J. J., NOGUERAS, J. J. and WOODHOUSE, S., 2000, Enterochro-maffin and serotonin cells are abnormal for patients with colonic inertia. Diseases of the Colon and Rectum, 43, 858–863.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.