Loss of mitochondrial membrane potential and caspase activation enhance apoptosis in irradiated K562 cells treated with herbimycin A

References

• Acehan D, Jiang X, Morgan D G, Heuser J E, Wang X, Akey C W. Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation. Mol Cell 2002; 9: 423–432
   PubMed Web of Science ®Google Scholar
• Adrain C, Martin S J. The mitochondrial apoptosome: A killer unleashed by the cytochrome seas. Trends Biochem Sci 2001; 26: 390–397
   PubMed Web of Science ®Google Scholar
• Alnemri E S, Livingston D J, Nicholson D W, Salvesen G, Thornberry N A, Wong W W, Yuan J. Human ICE/CED-3 protease nomenclature. Cell 1996; 87: 171
   PubMed Web of Science ®Google Scholar
• Bernardi P. The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death. Biochim Biophys Acta 1996; 1275: 5–9
   Google Scholar
• Bernardi P, Petronilli V, Di Lisa F, Forte M. A mitochondrial perspective on cell death. Trends Biochem Sci 2001; 26: 112–117
   PubMed Web of Science ®Google Scholar
• Bratton S B, Cohen G M. Apoptotic death sensor: An organelle's alter ego?. Trends Pharmacolog Sci 2001; 22: 306–315
   PubMed Web of Science ®Google Scholar
• Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, Brown J P, Sedivy J M, Kinzler K W, Vogelstein B. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 1998; 20: 1497–1501
   Google Scholar
• Cahill D P, Lengauer C, Yu J, Riggins G J, Willson J K, Markowitz S D, Kinzler K W, Vogelstein B. Mutations of mitotic checkpoint genes in human cancers. Nature 1998; 19: 300–303
   Google Scholar
• Calabretta B, Perrotti D. The biology of CML blast crisis. Blood 2004; 103: 2003–2012
   PubMed Web of Science ®Google Scholar
• Castedo M, Perfettini J L, Roumier T, Valent A, Raslova H, Yakushijin K, Horne D, Feunteun J, Lenoir G, Medema R, Vainchenker W, Kroemer G. Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy. Oncogene 2004; 23: 4353–4561
   PubMed Web of Science ®Google Scholar
• Chan T A, Hermeking H, Lengauer C, Kinzler K W, Vogelstein B. 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Nature 1999; 401: 616–620
   PubMed Web of Science ®Google Scholar
• Darzynkiewicz Z, Gong J, Juan G, Ardelt B, Traganos F. Cytometry of cyclin proteins. Cytometry 1996; 25: 1–13
   Google Scholar
• Desagher S, Martinou J C. Mitochondria as the central control point of apoptosis. Trends Cell Biol 2000; 10: 369–377
   PubMed Web of Science ®Google Scholar
• Earnshaw W C. Apoptosis. A cellular poison cupboard. Nature 1999; 397: 387–389
   PubMed Web of Science ®Google Scholar
• Fesik S W. Insights into programmed cell death through structural biology. Cell 2000; 103: 273–282
   PubMed Web of Science ®Google Scholar
• Gottlieb R A. Mitochondria: Execution central. FEBS Lett 2000; 482: 6–12
   PubMed Web of Science ®Google Scholar
• Hendry J H, West C M. Apoptosis and mitotic cell death: Their relative contributions to normal-tissue and tumour radiation response. Int J Radiation Biol 1997; 71: 709–719
   PubMed Web of Science ®Google Scholar
• Ianzini F, Cherubini R, Mackey M A. Mitotic catastrophe induced by exposure of V79 Chinese hamster cells to low-energy protons. Int J Radiation Biol 1999; 75: 717–723
   PubMed Web of Science ®Google Scholar
• Jeong S J, Jin Y H, Moon C W, Bae H R, Yoo Y H, Lee H S, Lee S H, Lim Y J, Lee J D, Jeong M H. Protein tyrosine kinase inhibitors modulate radiosensitivity and radiation-induced apoptosis in K562 cells. Radiation Res 2001; 156: 751–760
   PubMed Web of Science ®Google Scholar
• Jin P, Hardy S, Morgan D O. Nuclear localization of cyclinB1 controls mitotic entry after DNA damage. J Cell Biol 1998; 141: 875–885
   PubMed Web of Science ®Google Scholar
• Kerr J F, Wyllie A H, Currie A R. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26: 239–257
   PubMed Web of Science ®Google Scholar
• Kluck R M, Bossy-Wetzel E, Green D R, Newmeyer D D. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 1997; 275: 1132–1136
   PubMed Web of Science ®Google Scholar
• Kroemer G, Dallaporta B, Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Ann Rev Physiol 1998; 60: 619–642
   PubMed Web of Science ®Google Scholar
• Lane D P. Cancer. A death in the life of p53. Nature 1993; 362: 786–787
   PubMed Web of Science ®Google Scholar
• Li P, Nijhawan D, Budihardjo I, Srinivasula S M, Ahmad M, Alnemri E S, Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91: 479–489
   PubMed Web of Science ®Google Scholar
• Lozzio C B, Lozzio B B. Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. Blood 1975; 45: 321–334
   PubMed Web of Science ®Google Scholar
• Nabha S M, Mohammad R M, Dandashi M H, Coupaye-Gerard B, Aboukameel A, Pettit G R, Al Katib A M. Combretastatin-A4 prodrug induces mitotic catastrophe in chronic lymphocytic leukemia cell line independent of caspase activation and poly(ADP-ribose) polymerase cleavage. Clin Cancer Res 2002; 8: 2735–2741
   PubMed Web of Science ®Google Scholar
• Nagasawa H, Keng P, Harley R, Dahlberg W, Little J B. Relationship between γ-ray induced G2/M delay and cellular radiosensitivity. Int J Radiation Biol 1994; 66: 373–379
   PubMed Web of Science ®Google Scholar
• Okabe M, Kawamura K, Miyagishima T, Itaya T, Goodwyn D, Shoji M, Vogler W R, Sakurada K, Uehara M, Miyazaki T. Effect of herbimycin A, an inhibitor of tyrosine kinase, on protein tyrosine kinase activity and phosphotyrosyl proteins of Ph1-positive leukemia cells. Leukemia Res 1994; 18: 213–220
   PubMed Web of Science ®Google Scholar
• Okabe M, Uehara M. New insight into oncoprotein-targeted antitumor effect: Herbimycin A as an antagonist of protein tyrosine kinase against Ph1-positive leukemia cells. Leukemia Lymphoma 1993; 12: 41–49
   PubMed Web of Science ®Google Scholar
• Okabe M, Uehara Y, Miyagishima T, Itaya T, Tanaka M, Kuni-Eda Y, Kurosawa M, Miyazaki T. Effect of herbimycin A, an antagonist of tyrosine kinase, on bcr/abl oncoprotein-associated cell proliferations: Abrogative effect on the transformation of murine hematopoietic cells by transfection of a retroviral vector expressing oncoprotein P210bcr/abl and preferential inhibition on Ph1-positive leukemia cell growth. Blood 1992; 80: 1330–1338
   PubMed Web of Science ®Google Scholar
• Oltvai Z N, Milliman C L, Korsmeyer S J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 1993; 74: 609–619
   PubMed Web of Science ®Google Scholar
• Pietenpol J A, Stewart Z A. Cell cycle checkpoint signaling: cell cycle arrest versus apoptosis. Toxicology 2002; 181–182: 475–481
   PubMed Web of Science ®Google Scholar
• Roninson I B, Broude E V, Chang B D. If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells. Drug Resistance Update 2001; 4: 303–313
   PubMed Web of Science ®Google Scholar
• Sawyers C L, Denny C T, Witte O N. Leukemia and the disruption of normal hematopoiesis. Cell 1991; 64: 337–350
   PubMed Web of Science ®Google Scholar
• Scolnick D M, Halazonetis T D. The checkpoint protein Chfr defines a mitotic stress checkpoint that delays entry into metaphase. Nature 2000; 406: 430–435
   PubMed Web of Science ®Google Scholar
• Shankar S L, Mani S, O'guin K N, Kandimalla E R, Agrawal S, Shafit-Zagardo B. Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways. J Neurochem 2001; 79: 426–436
   PubMed Web of Science ®Google Scholar
• Song Q, Burrows S R, Smith G, Lees-Miller S P, Kumar S, Chan D W, Trapani J A, Alnemri E, Litwack G, Lu H, Moss D J, Jackson S, Lavin M F. Interleukin-1 beta-converting enzyme-like protease cleaves DNA-dependent protein kinase in cytotoxic T cell killing. J Exp Med 1996; 184: 619–626
   PubMed Web of Science ®Google Scholar
• Susin S A, Zamzami N, Kroemer G. Mitochondria as regulators of apoptosis: Doubt no more. Biochim Biophys Acta 1998; 1366: 151–165
   PubMed Web of Science ®Google Scholar
• Susin S A, Lorenzo H K, Zamzami N, Marzo I, Brenner C, Larochette N, Prevost M C, Alzari P M, Kroemer G. Mitochondrial release of Caspase-2 and -9 during the apoptotic process. J Exp Med 1999; 189: 381–394
   PubMed Web of Science ®Google Scholar
• Wyllie A H, Kerr J F, Currie A R. Cell death: the significance of apoptosis. Int Rev Cytol 1980; 68: 251–306
   PubMedGoogle Scholar
• Yoon H S, Moon S C, Kim N D, Park B S, Jeong M H, Yoo Y H. Genistein induces apoptosis of RPE-J cells by opening mitochondrial PTP. Biochem Biophys Res Comm 2000; 276: 151–156
   PubMed Web of Science ®Google Scholar
• Zamzami N, Marchetti P, Castedo M, Zanin C, Vayssiere J L, Petit P X, Kroemer G. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J Exp Med 1995; 181: 1661–1672
   PubMed Web of Science ®Google Scholar
• Zamzami N, Susin S A, Marchetti P, Hirsch T, Gomez-Monterrey I, Castedo M, Kroemer G. Mitochondrial control of nuclear apoptosis. J Exp Med 1996; 183: 1533–1544
   PubMed Web of Science ®Google Scholar