Chromosome breakpoint distribution of damage induced in peripheral blood lymphocytes by densely ionizing radiation

References

• Anderson R M, Marsden S J, Paice S J, Bristow A E, Kadhim M A, Griffin C S, Goodhead D T. Transmissible and nontransmissible complex chromosome aberrations characterized by three-color and mFISH define a biomarker of exposure to high-LET alpha particles. Radiation Research 2003; 159: 40–48
   PubMed Web of Science ®Google Scholar
• Anderson R M, Marsden S J, Wright E G, Kadhim M A, Goodhead D T, Griffin C S. Complex chromosome aberrations in peripheral blood lymphocytes as a potential biomarker of exposure to high-LET alpha-particles. International Journal of Radiation Biology 2000; 76: 31–42
   PubMed Web of Science ®Google Scholar
• Anderson R M, Stevens D L, Goodhead D T. M-FISH analysis shows that complex chromosome aberrations induced by alpha-particle tracks are cumulative products of localized rearrangements. Proceedings of the National Academy of Sciences of the United States of America 2002; 99: 12167–12172
   PubMed Web of Science ®Google Scholar
• Barquinero J F, Knehr S, Braselmann H, Figel M, Bauchinger M. DNA-proportional distribution of radiation-induced chromosome aberrations analysed by fluorescence in situ hybridization painting of all chromosomes of a human female karyotype. International Journal of Radiation Biology 1998; 74: 315–323
   PubMed Web of Science ®Google Scholar
• Bornfleth H, Edelmann P, Zink D, Cremer T, Cremer C. Quantitative motion analysis of subchromosomal foci in living cells using four-dimensional microscopy. Biophysics Journal 1999; 77: 2871–2886
   PubMed Web of Science ®Google Scholar
• Boutouil M, Fetni R, Qu J, Dallaire L, Richer C L, Lemieux N. Fragile site and interstitial telomere repeat sequences at the fusion point of a de novo (Y;13) translocation. Human Genetics 1996; 98: 323–327
   PubMedGoogle Scholar
• Braselmann H, Kulka U, Huber R, Figel H M, Zitzelsberger H. Distribution of radiation-induced exchange aberrations in all human chromosomes. International Journal of Radiation Biology 2003; 79: 393–403
   PubMed Web of Science ®Google Scholar
• Cafourkova A, Lukasova E, Kozubek S, Kozubek M, Govorun R D, Koutna I, Bartova E, Skalnikova M, Jirsova P, Pasekova R, Krasavin E A. Exchange aberrations among 11 chromosomes of human lymphocytes induced by gamma-rays. International Journal of Radiation Biology 2001; 77: 419–429
   PubMed Web of Science ®Google Scholar
• Chadwick K H, Leenhouts H P. The rejoining of DNA double-strand breaks and a model for the formation of chromosomal rearrangements. International Journal of Radiation Biology Relat Stud Phys Chem Med 1978; 33: 517–529
   PubMed Web of Science ®Google Scholar
• Cigarran S, Barrios L, Barquinero J F, Caballin M R, Ribas M, Egozcue J. Relationship between the DNA content of human chromosomes and their involvement in radiation-induced structural aberrations, analysed by painting. International Journal of Radiation Biology 1998; 74: 449–455
   PubMed Web of Science ®Google Scholar
• Cigarran S, Barrios L, Caballin M R, Barquinero J F. Effect of DMSO on radiation-induced chromosome aberrations analysed by FISH. Cytogenetic and Genome Research 2004; 104: 168–172
   PubMedGoogle Scholar
• Cremer C, Munkel C, Granzow M, Jauch A, Dietzel S, Eils R, Guan X Y, Meltzer P S, Trent J M, Langowski J, Cremer T. Nuclear architecture and the induction of chromosomal aberrations. Mutation Research 1996; 366: 97–116
   PubMedGoogle Scholar
• Cremer T, Cremer C. Chromosome territories, nuclear architecture and gene regulation in mammalian cells. Nature Reviews Genetics 2001; 2: 292–301
   PubMed Web of Science ®Google Scholar
• De Braekeleer M, Smith B. Two methods for measuring the non-randomness of chromosome abnormalities. Annals of Human Genetics 1988; 52(Pt 1)63–67
   PubMedGoogle Scholar
• Dessen P, Huret J. Chromosome 11 and Chromosome 13. Atlas of Genetic, Cytogenetic, Oncology and Haematology. 2002, URL: http://www.infobiogen.fr/services/chromcancer/indexbychromosome
   Google Scholar
• Figgitt M, Savage J RK. Interphase chromosome domain re-organization following irradiation. International Journal of Radiation Biology 1999; 75: 811–817
   PubMed Web of Science ®Google Scholar
• Goohead D T. Radiationtracks in biological materials: Initial damage in cells, DNA and associated structures. In Genes, Cancer and Radiation Protection, M L Mendelson. Published by NCRP. 1991; 25–37
   Google Scholar
• Goodhead D T. Track structure considerations in low-dose and low-dose rate effects of ionizing-radiation. Advances in Radiation Biology 1992; 16: 7–44
   Google Scholar
• Goodwin E H, Blakely E A, Tobias C A. Chromosomal damage and repair in G1-phase Chinese hamster ovary cells exposed to charged-particle beams. Radiation Research 1994; 138: 343–351
   PubMed Web of Science ®Google Scholar
• Johnson K L, Brenner D J, Nath J, Tucker J D, Geard C R. Radiation-induced breakpoint misrejoining in human chromosomes: random or non-random?. International Journal of Radiation Biology 1999; 75: 131–141
   PubMed Web of Science ®Google Scholar
• Johnson K L, Tucker J D, Nath J. Frequency, distribution and clonality of chromosome damage in human lymphocytes by multi-color FISH. Mutagenesis 1998; 13: 217–227
   PubMed Web of Science ®Google Scholar
• Kiuru A, Lindholm C, Auvinen A, Salomaa S. Localization of radiation-induced chromosomal breakpoints along human chromosome 1 using a combination of G-banding and FISH. International Journal of Radiation Biology 2000; 76: 667–672
   PubMed Web of Science ®Google Scholar
• Knehr S, Zitzelsberger H, Braselmann H, Nahrstedt U, Bauchinger M. Chromosome analysis by fluorescence in situ hybridization: further indications for a non-DNA-proportional involvement of single chromosomes in radiation-induced structural aberrations. International Journal of Radiation Biology 1996; 70: 385–392
   PubMed Web of Science ®Google Scholar
• Mahy N L, Perry P E, Bickmore W A. Gene density and transcription influence the localization of chromatin outside of chromosome territories detectable by FISH. Journal of Cell Biology 2002; 159: 753–763
   PubMed Web of Science ®Google Scholar
• Martinez-Lopez W, Boccardo E M, Folle G A, Porro V, Obe G. Intrachromosomal localization of aberration breakpoints induced by neutrons and gamma rays in Chinese hamster ovary cells. Radiation Research 1998; 150: 585–592
   PubMedGoogle Scholar
• Morton N E. Parameters of the human genome. Proceedings of the National Academy of Sciences of the United States of America 1991; 88: 7474–7476
   PubMed Web of Science ®Google Scholar
• Natarajan A T, Balajee A S, Boei J J, Chatterjee S, Darroudi F, Grigorova M, Noditi M, Oh H J, Slijepcevic P, Vermeulen S. Recent developments in the assessment of chromosomal damage. Intternational Journal of Radiation Biology 1994; 66: 615–623
   PubMed Web of Science ®Google Scholar
• Radulescu I, Elmroth K, Stenerlow B. Chromatin organization contributes to non-randomly distributed double-strand breaks after exposure to high-LET radiation. Radiation Research 2004; 161: 1–8
   PubMed Web of Science ®Google Scholar
• Rydberg B. Clusters of DNA damage induced by ionizing radiation: formation of short DNA fragments. II. Experimental detection. Radiation Research 1996; 145: 200–209
   PubMed Web of Science ®Google Scholar
• Savage J R. Cancer. Proximity matters. Science 2000; 290: 62–63
   PubMedGoogle Scholar
• Savage J R. Interchange and intra-nuclear architecture. Environ Mol Mutagen 1993; 22: 234–244
   PubMed Web of Science ®Google Scholar
• Savage J R, Papworth D G. The relationship of radiation-induced dicentric yield to chromosome arm number. Mutation Research 1973; 19: 139–143
   PubMedGoogle Scholar
• Savage J R, Simpson P J. FISH ‘painting’ patterns resulting from complex exchanges. Mutation Research 1994; 312: 51–60
   PubMed Web of Science ®Google Scholar
• Scarpato R, Lori D, Tomei A, Cipollini M, Barale R. High prevalence of chromosome 10 rearrangements in human lymphocytes after in vitro X-ray irradiation. International Journal of Radiation Biology 2000; 76: 661–666
   PubMedGoogle Scholar
• Surralles J, Darroudi F, Natarajan A T. Low level of DNA repair in human chromosome 1 heterochromatin. Genes Chromosomes and Cancer 1997; 20: 173–184
   PubMed Web of Science ®Google Scholar
• Tarone R E. Testing for non-randomness of events in sparse data situations. Annals of Human Genetics 1989; 53(Pt 4)381–387
   PubMedGoogle Scholar
• Visser A E, Aten J A. Chromosomes as well as chromosomal subdomains constitute distinct units in interphase nuclei. Journal of Cell Science 1999; 112(Pt 19)3353–3360
   PubMedGoogle Scholar
• Volpi E V, Chevret E, Jones T, Vatcheva R, Williamson J, Beck S, Campbell R D, Goldsworthy M, Powis S H, Ragoussis J, Trowsdale J, Sheer D. Large-scale chromatin organization of the major histocompatibility complex and other regions of human chromosome 6 and its response to interferon in interphase nuclei. Journal of Cell Science 2000; 113(Pt 9)1565–1576
   PubMedGoogle Scholar
• Wu H, Durante M, Lucas J N. Relationship between radiation-induced aberrations in individual chromosomes and their DNA content: effects of interaction distance. International Journal of Radiation Biology 2001; 77: 781–786
   PubMed Web of Science ®Google Scholar
• Wu H, George K, Yang T C. Estimate of the frequency of true incomplete exchanges in human lymphocytes exposed to 1 GeV/u Fe ions in vitro. International Journal of Radiation Biology 1999; 75: 593–599
   PubMed Web of Science ®Google Scholar
• Xiao Y, Natarajan A T. Non-proportional involvement of Chinese hamster chromosomes 3, 4, 8 and 9 in X-ray-induced chromosomal aberrations. International Journal of Radiation Biology 1999; 75: 943–951
   PubMedGoogle Scholar