Increased excretion of collagen crosslinks in irradiated patients indicates destruction of collagen

References

• Acil Y, Brinckmann J, Behrens P, Müller P K, Batge B. Semipreparative isolation of collagen types I, II, III and V by sodium dodecyl sulfatepolyacrylamide gel electrophoresis and electroelution. Journal of Chromatography A 1997; 758: 313–318
   PubMed Web of Science ®Google Scholar
• Acil Y, Müller P K. A rapid method for the isolation of the mature collagen cross-links, hydroxylysylpyridinoline (HP) and lysylpyridinoline (LP). Journal of Chromatography A 1994; 664: 183–188
   PubMed Web of Science ®Google Scholar
• Acil Y, Brinckmann J, Notbohm H, Müller P K, Batge B. Changes with age in the urinary excretion of hydroxylysylpyridinoline (HP) and lysylpyridinoline (LP). Scandinavian Journal of Clinical Labor Investigation 1996; 56(3)275–283
   PubMed Web of Science ®Google Scholar
• Acil Y, Springer I N, Prasse J G, Hedderich J, Jepsen S. Concentration of collagen cross-links in human dentin bears no relation to the individual age. International Journal of Legal Medicine 2002; 116(6)340–343
   PubMed Web of Science ®Google Scholar
• Acil Y, Springer I N, Behrens P, Ulrich K P, Hedderich J, Bruns J. Differential enhancement of collagen crosslink excretion in cases of osteosarcoma and chondrosarcom. Journal of Cancer Research 2003; 129: 583–588
   Web of Science ®Google Scholar
• Black D, Farquharson C, Robins S P. Excretion of pyridinium cross-links of collagen in ovariectomized rats as urinary markers for increased bone resorption. Calcification Tissue International 1988; 44(5)343–347
   Web of Science ®Google Scholar
• Bures M F, Wuehrmann A H. Bone-remodelling dynamics following local x-irradiation: Part II. Journal of Dental Research 1969a; 48: 376–384
   PubMedGoogle Scholar
• Bures M F, Wuehrmann A H. Bone-remodelling dynamics following local x-irradiation: Part II. Journal of Dental Research 1969b; 48: 904–908
   PubMedGoogle Scholar
• Coleman R E, Houston S, James I, Rodger A, Rubens R D, Leonard R C, Ford J. Preliminary results of the use of urinary excretion of pyridinium crosslinks for monitoring metastatic bone disease. British Journal of Cancer 1992; 65(5)766–768
   PubMed Web of Science ®Google Scholar
• Diel I J, Solmayer E F, Bastert G. Bisphosphonates and the prevention of metastasis: First evidences from preclinical and clinical studies. Cancer 2000; 88: 3080–3088
   PubMedGoogle Scholar
• Eyre D. New biomarkers of bone resorption. Journal Clinical Endocrinology & Metabolism 1992; 74(3)470A–470C
   Web of Science ®Google Scholar
• Fajardo L F. Pathology of radiation injury. Masson, New York 1982
   Google Scholar
• Fantner G E, Hassenkam T, Kindt J H, Weaver J C, Birkedal H, Pechnik L, Cutroni J A, Cidade G A, Stucky G D, Morse D E, Hansma P K. Sacrificial bonds and hidden length dissipate energy as mineralized fibrils separate during bone fracture. Nature Materials 2005; 4: 612–616
   PubMed Web of Science ®Google Scholar
• Holler U, Hoecht S, Wudel E, Hinkelbein W. Osteoradionecrosis after radiotherapy for gynecologic tumors. Strahlentherapie Onkologie 2001; 177(6)291–295
   PubMed Web of Science ®Google Scholar
• Hoskin P J, Stratford M RL, Folkes L K, Regan J, Yarnold J R. Effect of local radiotherapy for bone pain on urinary markers of osteoclast activity. Lancet 2000; 355: 1428–1429
   PubMed Web of Science ®Google Scholar
• Inoue Y, Miki C, Ojima E, Nomoto J, Kusunoki M. Pelvic insufficiency fractures after preoperative radiotherapy for rectal carcinoma. International Journal of Clinical Oncology 2003; 8(5)336–339
   PubMedGoogle Scholar
• Jung A, Bisaz S, Fleisch H. The binding of pyrophosphate and two diphosphonates by hydroxyapatite crystals. Calcifed Tissue Research 1973; 11: 269–280
   PubMedGoogle Scholar
• Kanis J A, McCloskey E V. Bone turnover and biochemical markers in malignancy. Cancer 1997; 15(80 Suppl.)1538–1545
   Google Scholar
• King M A, Casarett G W, Weber D A. A study of irradiated bone: Part I. Histopathology and physiologic changes. Journal of Nuclear Medicine 1979; 20: 1142–1149
   PubMed Web of Science ®Google Scholar
• Kolar J, Vrabec R. Strahlenbedingte Knochenschäden. Handbuch der medizinischen Radiologie, Diethelm L. Hrsg. Springer, Berlin-Heidelberg-New York 1976; V/1: 389–512, Röntgendiagnostik der Skeletterkrankungen
   Google Scholar
• Kurth A A, Kim S Z, Bauss F, Muller R, Hovy L. [Anti-osteolytic therapy preserves trabecular structure and mechanical properties of bone in tumor osteolysis]. Zeitung für Orthopädie und Ihre Grenzgebiete 2000; 138(2)146–151
   PubMed Web of Science ®Google Scholar
• Matsubayashi T H, Koga Y, Nishiyama S. The reparative process of metastatic bone lesions after radiotherapy. Japanese Journal of Clinical Oncology 1981; 11(Suppl)253–264
   Google Scholar
• Mose S, Pfitzner D, Rahn A, Nierhoff C, Schiemann M, Bottcher H D. Role of radiotherapy in the treatment of multiple myeloma. Strahlentherapie und Onkologie 2000; 176: 506–512
   PubMed Web of Science ®Google Scholar
• Papatheofanis F J. Quantitation of biochemical markers of bone resorption following strontium-89-chloride therapy for metastatic prostatic carcinoma. Journal of Nuclear Medicine 1997; 38: 1175–1179
   PubMed Web of Science ®Google Scholar
• Rieden K, Adolph J, Lellig U, Zum Winkel K. The radiotherapeutic effect on bone metastases in relation to the frequency of metastases, sites of metastases and histology of the primary tumor. Strahlentherapie und Onkologie 1989; 165: 380–385
   PubMed Web of Science ®Google Scholar
• Riekki R, Jukkola A, Sassi M L, Hoyhtya M, Kallioinen M, Risteli J, Oikarinen A. Modulation of skin collagen metabolism by irradiation: Collagen synthesis is increased in irradiated human skin. British Journal of Dermatology 2000; 142: 874–880
   PubMed Web of Science ®Google Scholar
• Sato M, Grasser W, Endo N, Akins R, Simmons H, Thompson D D, Golub E, Rodan G A. Bisphosphonates action: Alenodrate localization in rat bone and effects on osteoclast ultrastructure. Journal of Clinical Investigation 1991; 88: 2095–2105
   PubMed Web of Science ®Google Scholar
• Springer I N, Terheyden H, Geiss S, Harle F, Hedderich J, Acil Y. Particulated bone grafts effectiveness of bone cell supply. Clinical Oral Implants Research 2004; 15(2)205–212
   PubMed Web of Science ®Google Scholar
• Springer I N, Terheyden H, Suhr M A, Warnke P, Dunsche A, Tiemann M, Acil Y. Follow-up of collagen crosslink excretion in patients with oral squamous cell carcinoma and analysis of tissue samples. British Journal of Cancer 2003a; 89(9)1722–1728
   PubMed Web of Science ®Google Scholar
• Springer I N, Terheyden H, Dunsche A, Czech N, Tiemann M, Hedderich J, Acil Y. Collagen crosslink excretion and staging of oral cancer. British Journal of Cancer 2003b; 88(7)1105–1110
   PubMed Web of Science ®Google Scholar
• Springer I N, Niehoff P, Warnke P H, Bocek G, Kovacs G, Suhr M, Wiltfang J, Acil Y. Radiation caries – radiogenic destruction of dental collagen. Oral Oncology 2005; 41: 723–728
   PubMed Web of Science ®Google Scholar
• Weber W, Rosler H P, Doll G, Dostert M, Kutzner J, Schild H. The percutaneous irradiation of osteolytic bone metastases – a course assessment. Strahlentherapie und Onkologie 1992; 168(5)275–280
   PubMedGoogle Scholar