203
Views
10
CrossRef citations to date
0
Altmetric
Original Articles

Resveratrol ameliorates ionizing irradiation-induced long-term immunosuppression in mice

ORCID Icon, ORCID Icon, , , ORCID Icon, , ORCID Icon & ORCID Icon show all
Pages 28-36 | Received 03 Jun 2017, Accepted 07 Nov 2017, Published online: 12 Dec 2017

References

  • Al Ghamdi AA, Badr G, Hozzein WN, Allam A, Al-Waili NS, Al-Wadaan MA, Garraud O. 2015. Oral supplementation of diabetic mice with propolis restores the proliferation capacity and chemotaxis of b and t lymphocytes towards ccl21 and cxcl12 by modulating the lipid profile, the pro-inflammatory cytokine levels and oxidative stress. BMC Immunol. 16:54.
  • Assayed ME. 2010. Radioprotective effects of black seed (nigella sativa) oil against hemopoietic damage and immunosuppression in gamma-irradiated rats. Immunopharmacol Immunotoxicol. 32:284–296.
  • Athar M, Back JH, Tang X, Kim KH, Kopelovich L, Bickers DR, Kim AL. 2007. Resveratrol: a review of preclinical studies for human cancer prevention. Toxicol Appl Pharmacol. 224:274–283.
  • Baur JA, Sinclair DA. 2006. Therapeutic potential of resveratrol: The in vivo evidence. Nat Rev Drug Discov. 5:493–506.
  • Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mostoslavsky R, Cohen HY, et al. 2004. Stress-dependent regulation of foxo transcription factors by the sirt1 deacetylase. Science. 303:2011–2015.
  • Burchiel SW, Lauer FT, McDonald JD, Reed MD. 2004. Systemic immunotoxicity in aj mice following 6-month whole body inhalation exposure to diesel exhaust. Toxicol Appl Pharmacol. 196:337–345.
  • Dayal R, Singh A, Pandey A, Mishra KP. 2014. Reactive oxygen species as mediator of tumor radiosensitivity. J Can Res Ther. 10:811-8–25579513.
  • Demidenko ZN, Blagosklonny MV. 2009. At concentrations that inhibit mtor, resveratrol suppresses cellular senescence. Cell Cycle. 8:1901–1904.
  • Diaz-Ruiz A, Gonzalez-Freire M, Ferrucci L, Bernier M, de Cabo R. 2015. Sirt1 synchs satellite cell metabolism with stem cell fate. Cell Stem Cell. 16:103–104.
  • Duan WJ, Liu FL, He RR, Yuan WL, Li YF, Tsoi B, Su WW, Yao XS, Kurihara H. 2013. Autophagy is involved in the effects of resveratrol on prevention of splenocyte apoptosis caused by oxidative stress in restrained mice. Mol Nutr Food Res. 57:1145–1157.
  • Duan Y, Chen F, Yao X, Zhu J, Wang C, Zhang J, Li X. 2015. Protective effect of lycium ruthenicum murr. Against radiation injury in mice. IJERPH. 12:8332–8347.
  • Fan ZL, Wang ZY, Zuo LL, Tian SQ. 2012. Protective effect of anthocyanins from lingonberry on radiation-induced damages. IJERPH. 9:4732–4743.
  • Feng YH, Zhou WL, Wu QL, Li XY, Zhao WM, Zou JP. 2002. Low dose of resveratrol enhanced immune response of mice. Acta Pharmacol Sin. 23:893–897.
  • Finch SC. 1987. Landmark perspective: Acute radiation syndrome. JAMA. 258:664–667.
  • Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, Lagorce-Pages C, Tosolini M, Camus M, Berger A, Wind P, et al. 2006. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science. 313:1960–1964.
  • Gao X, Xu YX, Janakiraman N, Chapman RA, Gautam SC. 2001. Immunomodulatory activity of resveratrol: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production. Biochem Pharmacol. 62:1299–1308.
  • Ghafoori P, Marks LB, Vujaskovic Z, Kelsey CR. 2008. Radiation-induced lung injury. Assessment, management, and prevention. Oncology. 22:37–47. discussion 52–3.
  • Ghazy AA, Abu El-Nazar SY, Ghoneim HE, Taha AR, Abouelella AM. 2015. Effect of murine exposure to gamma rays on the interplay between th1 and th2 lymphocytes. Front Pharmacol. 6:74.
  • Ghosh HS, McBurney M, Robbins PD. 2010. Sirt1 negatively regulates the mammalian target of rapamycin. PLoS One. 5:e9199–20169165.
  • Guarente L. 2014. Linking DNA damage, nad(+)/sirt1, and aging. Cell Metab. 20:706–707.
  • Igietseme JU, Eko FO, He Q, Black CM. 2004. Antibody regulation of tcell immunity: Implications for vaccine strategies against intracellular pathogens. Expert Rev Vaccines. 3:23–34.
  • Iuga C, Alvarez-Idaboy JR, Russo N. 2012. Antioxidant activity of trans-resveratrol toward hydroxyl and hydroperoxyl radicals: a quantum chemical and computational kinetics study. J Org Chem. 77:3868–3877.
  • Jagetia GC, Reddy TK. 2005. Modulation of radiation-induced alteration in the antioxidant status of mice by naringin. Life Sci. 77:780–794.
  • Jameson SC. 2005. T cell homeostasis: Keeping useful t cells alive and live t cells useful. Semin Immunol. 17:231–237.
  • Kikuchi K, Kasai H, Watanabe A, Lai AY, Kondo M. 2008. Il-7 specifies b cell fate at the common lymphoid progenitor to pre-prob transition stage by maintaining early b cell factor expression. J Immunol. 181:383–392.
  • Kim KO, Park H, Kim HS. 2014. Effects of high-protein diet and/or resveratrol supplementation on the immune response of irradiated rats. JFN. 19:156–163.
  • Lin KH, Lin KC, Lu WJ, Thomas PA, Jayakumar T, Sheu JR. 2015. Astaxanthin, a carotenoid, stimulates immune responses by enhancing ifn-gamma and il-2 secretion in primary cultured lymphocytes in vitro and ex vivo. Int J Mol Sci. 17:E44. doi: 10.3390/ijms17010044
  • Luo-Owen X, Pecaut MJ, Rizvi A, Gridley DS. 2012. Low-dose total-body gamma irradiation modulates immune response to acute proton radiation. Radiat Res. 177:251–264.
  • Maccalli C, Scaramuzza S, Parmiani G. 2009. Tnk cells (nkg2d + cd8+ or cd4+ t lymphocytes) in the control of human tumors. Cancer Immunol Immunother. 58:801–808.
  • Malhotra P, Adhikari M, Mishra S, Singh S, KP, Singh SK, Kumar R. 2016. N-acetyl tryptophan glucopyranoside (natg) as a countermeasure against gamma radiation-induced immunosuppression in murine macrophage j774a.1 cells. Free Radic Res. 50:1265–1278.
  • Michan S, Sinclair D. 2007. Sirtuins in mammals: Insights into their biological function. Biochem J. 404:1–13.
  • Mishra S, Patel DD, Bansal DD, Kumar R. 2016. Semiquinone glucoside derivative provides protection against gamma-radiation by modulation of immune response in murine model. Environ Toxicol. 31:478–488.
  • Park HS, Kim S, Lee Y, Choi MS, Choi MU. 2006. Alteration of lipid composition of rat thymus during thymic atrophy by whole-body x-irradiation. Int J Radiat Biol. 82:129–137.
  • Pervaiz S, Holme AL. 2009. Resveratrol: Its biologic targets and functional activity. Antioxid Redox Signal. 11:2851–2897.
  • Saiko P, Szakmary A, Jaeger W, Szekeres T. 2008. Resveratrol and its analogs: Defense against cancer, coronary disease and neurodegenerative maladies or just a fad?. Mut Res. 658:68–94.
  • Schluns KS, Kieper WC, Jameson SC, Lefrancois L. 2000. Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo. Nat Immunol. 1:426–432.
  • Schmeisser H, Bekisz J, Zoon KC. 2014. New function of type i ifn: Induction of autophagy. J Interferon Cytokine Res. 34:71–78.
  • Singh VK, Singh PK, Wise SY, Posarac A, Fatanmi OO. 2013. Radioprotective properties of tocopherol succinate against ionizing radiation in mice. J Radiat Res..54:210–220.
  • Tao L, Ding Q, Gao C, Sun X. 2016. Resveratrol attenuates neuropathic pain through balancing pro-inflammatory and anti-inflammatory cytokines release in mice. Int Immunopharmacol. 34:165–172.
  • Tucci P. 2012. Caloric restriction: Is mammalian life extension linked to p53?. Aging (Albany NY). 4:525–534.
  • Wang H, Yang YL, Zhang H, Yan H, Wu XJ, Zhang CZ. 2014. Administration of the resveratrol analogues isorhapontigenin and heyneanol-a protects mice hematopoietic cells against irradiation injuries. BioMed Res Int. 2014:282657–25050334.
  • Wang SJ, Bo QY, Zhao XH, Yang X, Chi ZF, Liu XW. 2013. Resveratrol pre-treatment reduces early inflammatory responses induced by status epilepticus via mtor signaling. Brain Res. 1492:122–129.
  • Wang Y, Meng A, Lang H, Brown SA, Konopa JL, Kindy MS, Schmiedt RA, Thompson JS, Zhou D. 2004. Activation of nuclear factor kappab in vivo selectively protects the murine small intestine against ionizing radiation-induced damage. Cancer Res. 64:6240–6246.
  • Wang Y, Schulte BA, LaRue AC, Ogawa M, Zhou D. 2006. Total body irradiation selectively induces murine hematopoietic stem cell senescence. Blood. 107:358–366.
  • Zhang H, Li J, Wang YY, Meng AM, Liu Q, Wang L, Chen FH, Wang XC, Zhai ZB, Fu Y, et al. 2012. Retinoblastoma 94 enhances radiation treatment of esophageal squamous cell carcinoma in vitro and in vivo. J Radiat Res. 53:117–124.
  • Zhang H, Zhai Z, Wang Y, Zhang J, Wu H, Wang Y, Li C, Li D, Lu L, Wang X, et al. 2013. Resveratrol ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice. Free Radic Biol Med. 54:40–50.
  • Zou T, Yang Y, Xia F, Huang A, Gao X, Fang D, Xiong S, Zhang J. 2013. Resveratrol inhibits cd4+ t cell activation by enhancing the expression and activity of sirt1. PLoS One. 8:e75139.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.