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International Journal of Radiation Biology Volume 96, 2020 - Issue 1: Non-clinical Radiation Biology and Pharmacology Models: Appraisal of State-of-the-Art and Innovation
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Dosimetry

Development of a biodosimeter for radiation triage using novel blood protein biomarker panels in humans and non-human primates

Robert P. BalogSRI International, Menlo Park, CA, USA; View further author information
,
Rowena BacherSRI International, Menlo Park, CA, USA; View further author information
,
Polly ChangSRI International, Menlo Park, CA, USA; View further author information
,
Michael GreensteinSRI International, Menlo Park, CA, USA; View further author information
,
Songeeta JammalamadakaSRI International, Menlo Park, CA, USA; View further author information
,
Harold JavitzSRI International, Menlo Park, CA, USA; View further author information
,
Susan J. KnoxDepartment of Radiation Oncology, Stanford University, Stanford, CA, USAView further author information
,
Shirley LeeSRI International, Menlo Park, CA, USA; View further author information
,
Hua LinSRI International, Menlo Park, CA, USA; View further author information
,
Thomas ShalerSRI International, Menlo Park, CA, USA; View further author information
,
Lei ShuraDepartment of Radiation Oncology, Stanford University, Stanford, CA, USAView further author information
,
Paul SteinSRI International, Menlo Park, CA, USA; View further author information
,
Kathryn ToddSRI International, Menlo Park, CA, USA; View further author information
&
David E. CooperSRI International, Menlo Park, CA, USA; Correspondence[email protected]
View further author information
 show all
Pages 22-34 | Received 05 Jun 2018, Accepted 22 Sep 2018, Published online: 03 Jan 2019

References

  • Barrett A, Jacobs A, Kohn J, Raymond J, Powles RL. 1982. Changes in serum amylase and its isoenzymes after whole body irradiation. Br Med J (Clin Res Ed). 285:170–171.
  • Balog RP, Chang P, Javitz H, Lee S, Lin H, Shaler T, Cooper DE. 2018. Development of a point-of-care radiation biodosimeter: studies using novel protein biomarker panels in non-human primates. To be published this issue.
  • Bazan JG, Chang P, Balog R, D'Andrea A, Shaler T, Lin H, Lee S, Harrison T, Shura L, Schoen L, et al. 2014. Novel human radiation exposure biomarker panel applicable for population triage. Int J Radiat Oncol Biol Phys. 90:612–619.
  • Bertho JM, Demarquay C, Frick J, Joubert C, Arenales S, Jacquet N, Sorokine-Durm I, Quang Chau Q, Lopez M, Aigueperse J, et al. 2001. Level of Flt3-ligand in plasma: a possible new bio-indicator for radiation-induced aplasia. Intern J Radiat Biol. 77:703–712.
  • Bertho JM, Roy L, Souidi M, Benderitter M, Gueguen Y, Lataillade JJ, Prat M, Fagot T, De Revel T, Gourmelon P. 2008. New biological indicators to evaluate and monitor radiation-induced damage: an accident case report. Radiat Res. 169:543–550.
  • Bertho JM, Roy L, Souidi M, Benderitter M, Bey E, Racine R, Fagot T, Gourmelon P. 2009. Initial evaluation and follow-up of acute radiation syndrome in two patients from the Dakar accident. Biomarkers. 14:94–102.
  • Buddemeier B. 2015. Medical needs in the aftermath of nuclear terrorism. LLNL-PRES-677346 (Presented at EPR BioDose 2015, Hanover, NH, October 48, 2015).
  • Buddemeier BR. 2011. National capital region: Key response planning factors for the aftermath of nuclear terrorism. Lawrence Livermore National Lab.(LLNL), Livermore, CA (United States). Report No: LLNL-TR-512111. Available from: http://fas.org/irp/agency/dhs/fema/ncr.pdf.
  • Citrin DE, Hitchcock YJ, Chung E, Frandsen J, Urick M, Shield W, Gaffney D. 2012. Determination of cytokine protein levels in oral secretions in patients undergoing radiotherapy for head and neck malignancies. Radiat Oncol. 7:64. doi: 10.1186/1748-717X-7-64.
  • Deshmane SL, Kremlev S, Amini S, Sawaya BE. 2010. Monocyte chemoattractant protein-1 (MCP-1): an overview. J Interferon Cytokine Res. 29:313–326.
  • Dressman HK, Muramoto GG, Chao NJ, Meadows S, Marshall D, Ginsburg GS, Nevins JR, Chute JP. 2007. Gene expression signatures that predict radiation exposure in mice and humans. PLoS Med. 4:e106.
  • Fisher RA. 1925. Statistical Methods for Research Workers. Oliver and Boyd (Edinburgh). ISBN 0-05-002170-2.
  • Gaugler M-H, Vereycken-Holler V, Squiban C, Vandamme M, Vozenin-Brotons M-C, Benderitter M. 2005. Pravastatin limits endothelial activation after irradiation and decreases the resulting inflammatory and thrombotic responses. Radiat Res. 163:479–487.
  • Guipaud O, Benderitter M. 2009. Protein biomarkers for radiation exposure: towards a proteomic approach as a new investigation tool. Ann Ist Super Sanita. 45:278–286.
  • Junglee D, Katrak A, Mohiuddin J, Blacklock H, Prentice HG, Dandona P. 1986. Salivary amylase and pancreatic enzymes in serum after total body irradiation. Clin Chem. 32:609–610.
  • Kenins L, Gill JW, Boyd RL, Holländer GA, Wodnar-Filipowicz A. 2008. Intrathymic expression of Flt3 ligand enhances thymic recovery after irradiation. J Exp Med. 205:523–531.
  • Kishima HK, Kirkham WR, Andrews JR. 1965. Post irradiation sialadenitis. A study of the clinical features, histopathologic changes and serum enzyme variations following irradiation of human salivary glands. Am J Roentgenol Radium Ther Nucl Med. 94:271–291.
  • Leslie MD, Dische S. 1992. Changes in serum and salivary amylase during radiotherapy for head and neck cancer: a comparison of conventionally fractionated radiotherapy with CHART. Radiother Oncol. 24:27–31.
  • Moriconi F, Christiansen H, Raddatz D, Dudas J, Hermann RM, Rave-Fränk M, Sheikh N, Saile B, Hess CF, Ramadori G. 2008. Effect of radiation on gene expression of rat liver chemokines: in vivo and in vitro studies. Radiat Res. 169:162–169.
  • Nalla AK, Gogineni VR, Gupta R, Dinh DH, Rao JS. 2011. Suppression of uPA and uPAR blocks radiation-induced MCP-1 mediated recruitment of endothelial cells in meningioma. Cell Signal. 23:1299–1310.
  • Port M, Majewski M, Herodin F, Valente M, Drouet M, Forcheron F, Tichy A, Sirak I, Zavrelova A, Malkova A, et al. 2018. Validating baboon ex vivo and in vivo radiation-related gene expression with corresponding human data. Radiat Res. 189:389–398.
  • Siva S, MacManus M, Kron T, Best N, Smith J, Lobachevsky P, Ball D, Martin O. 2014. A pattern of early radiation-induced inflammatory cytokine expression is associated with lung toxicity in patients with non-small cell lung cancer. PLoS One. 9:e109560.

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