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Mini-Review

Peggy Louise Olive: A journey through the ‘comet’ and beyond

Pages 344-348 | Received 05 Sep 2019, Accepted 29 Oct 2019, Published online: 21 Nov 2019

References

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  • Dorie MJ, Kovacs MS, Gabalski EC, Adam M, Le QT, Bloch DA, Pinto HA, Terris DJ, Brown JM. 1999. DNA damage measured by the comet assay in head and neck cancer patients treated with tirapazamine. Neoplasia. 1(5):461–467.
  • McLaren DB, Pickles T, Thomson T, Olive PL. 1997. Impact of nicotinamide on human tumour hypoxic fraction measured using the comet assay. Radiother Oncol. 45(2):175–182.
  • Møller P. 2018. The comet assay: ready for 30 more years. Mutagenesis. 33(1):1–7.
  • OECD. 2016. Test No. 489: In Vivo Mammalian Alkaline Comet Assay, OECD Guidelines for the Testing of Chemicals, Section 4, OECD Publishing, Paris, https://doi.org/10.1787/9789264264885-en.
  • Olive PL. 1989. Cell proliferation as a requirement for development of the Contact Effect in Chinese Hamster V79 Spheroids. Radiat Res. 117(1):79–92.
  • Olive PL. 2011. Retention of γH2AX foci as an indication of lethal DNA damage. Radiother Oncol. 101(1):18–23.
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  • Ostling O, Johanson KJ. 1984. Microelectrophoretic study of radiation induced DNA damages in individual mammalian cells. Biochem Biophys Res Commun. 123(1):291–298.
  • Partridge SE, Aquino-Parsons C, Luo C, Green A, Olive PL. 2001. A pilot study comparing intratumoral oxygenation using the comet assay following 2.5% and 5% carbogen and 100% oxygen. Int J Radiat Oncol Biol Phys. 49(2):575–580.
  • Rogakou EP, Nieves-Neira W, Boon C, Pommier Y, Bonner WM. 2000. Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AXhistone at serine 139. J Biol Chem. 275(13):9390–9395.
  • Singh NP. 2016. The comet assay: reflections on its development, evolution and applications. Mutat Res Rev Mutat Res. 767:23–30.
  • Singh NP, McCoy MT, Tice RR, Schneider EL. 1988. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res. 175(1):184–191.

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