Dosimetry study on Auger electron-emitting nuclear medicine radioisotopes in micrometer and nanometer scales using Geant4-DNA simulation

References

• Alexandre ST, João Manuel RS. 2010. Evaluating 99mTc Auger electrons for targeted tumor radiotherapy by computational methods. Med Phys. 37(7 Pt 1):3551–3559.
   PubMed Web of Science ®Google Scholar
• Agostinelli S, Allison J, Amako K, Apostolakis J, Araujo H, Arce P, Asai M, Axen D, Banerjee S, Barrand G, et al. 2003. Geant4—a simulation toolkit. Inst Meth Phys Res A. 506(3):250–303.
   Web of Science ®Google Scholar
• André T, Morini F, Karamitros M, Delorme R, Le Loirec C, Campos L, Champion C, Groetz J-E, Fromm M, Bordage M-C, et al. 2014. Comparison of Geant4-DNA simulation of S-values with other Monte Carlo codes. Nucl Instrum Meth Phys Res B Beam Interact Mater At. 319:87–94.
   Web of Science ®Google Scholar
• Bernal MA, Bordage MC, Brown JMC, Davidkova M, Delage E, Bitar ZE, Enger SA, Francis Z, Guatelli S, Ivanchenko VN, et al. 2015. Track structure modeling in liquid water: a review of the Geant4-DNA very low energy extension of the Geant4 Monte Carlo simulation toolkit. Phys Med. 31(8):861–874.
   PubMed Web of Science ®Google Scholar
• Bernal MA, Liendo JA. 2009. An investigation on the capabilities of the PENELOPE MC code in nanodosimetry. Med Phys. 36(2):620–625.
   PubMed Web of Science ®Google Scholar
• Bousis C. 2011. Dosimetry on sub-cellular level for intracellular incorporated Auger-electron-emitting radionuclides: a comparison of Monte Carlo simulations and analytic calculations. Radiat Prot Dosim. 143(1):33–41.
   PubMed Web of Science ®Google Scholar
• Bousis C, Emfietzoglou D, Hadjidoukas P, Nikjoo H. 2010. Monte Carlo single-cell dosimetry of Auger-electron emitting radionuclides. Phys Med Biol. 55(9):2555–2572.
   PubMed Web of Science ®Google Scholar
• Bousis C, Emfietzoglou D, Nikjoo H. 2012. Monte Carlo single-cell dosimetry of I-131, I-125 and I-123 for targeted radioimmuno therapy of B-cell lymphoma. Int J Radiat Biol. 88:1–8.
   Web of Science ®Google Scholar
• Champion C, Zanotti-Fregonara P, Hindie E. 2008. CELLDOSE: a Monte Carlo code to assess electron dose distribution—S values for 131I in spheres of various sizes. J Nucl Med. 49(1):151–157.
   PubMed Web of Science ®Google Scholar
• Charlton DE, Humm JL. 1988. A method of calculating initial DNA strand breakage following the decay of incorporated 125 I. Int J Radiat Biol. 53(3):353–365.
   Web of Science ®Google Scholar
• Chatterjee A, Magee JL. 1985. Theoretical investigation of the production of strand breaks in DNA by water radicals. Radiat Prot Dosim. 13(1–4):137–140.
   Web of Science ®Google Scholar
• Chauvie S, Francis Z, Guatelli S, Incerti S, Mascialino B, Moretto F, Nieminen P, Pia MG. 2007. Geant4 physics processes for microdosimetry simulation: design foundation and implementation of the first set of models. IEEE Trans Nucl Sci. 54(6):2619–2628.
   Web of Science ®Google Scholar
• Emfietzoglou D, Kostarelos K, Hadjidoukas P, Bousis C, Fotopoulos A, Pathak A, Nikjoo H. 2008. Subcellular S-factors for low-energy electrons: a comparison of Monte Carlo simulations and continuous-slowing-down calculations. Int J Radiat Biol. 84(12):1034–1044.
   PubMed Web of Science ®Google Scholar
• Falzone N, Fernandez-Varea JM, Flux G, Vallis KA. 2015. Monte Carlo evaluation of Auger electron-emitting theragnostic radionuclides. J Nucl Med. 56(9):1441–1615.
   PubMed Web of Science ®Google Scholar
• Falzone N, Lee BQ, Fernandez-Varea JM, Kartsonaki C, Stuchbery AE, Kibedi T, Vallis KA. 2017. Absorbed dose evaluation of auger electron-emitting radionuclides: impact of input decay spectra on dose point kernels and S-values. Phys Med Biol. 62(6):2239–2253.
   PubMed Web of Science ®Google Scholar
• Fourie H, Newman RT, Slabbert JP. 2015. Microdosimetry of the Auger electron emitting 123I radionuclide using Geant4-DNA simulations. Phys Med Biol. 60(8):3333–3346.
   PubMed Web of Science ®Google Scholar
• Ftacnikova S, Bohm R. 2000. Monte Carlo calculations of energy deposition on cellular, multicellular and organ level for Auger emitters. Radiat Prot Dosim. 92:279–288.
   Web of Science ®Google Scholar
• Ftacnikova S, Bohm R. 2000. Monte Carlo calculations of energy deposition in DNA for Auger emitters. Radiat Prot Dosim. 92:269–278.
   Web of Science ®Google Scholar
• Gardin I, Faraggi M, Huc E, Bok BD. 1995. Modeling of the relationship between cell dimensions and mean electron dose delivered to the cell nucleus: application to five radionuclides used in nuclear medicine. Phys Med Biol. 40(6):1001–1014.
   PubMed Web of Science ®Google Scholar
• Geant4. 2003. Geant4 collaboration web site: http://cern.ch/geant4.
   Google Scholar
• Germain D, Gentilhomme O, Bryon PA, Coiffier B. 1981. Cellules sanguines et organes hematopoletiques. In: Simep SA, editor. Physiologie humaine. Villeurbanne: Simep SA; p. 184–247.
   Google Scholar
• Goddu S, Howell R, Bouchet L, Bolch W, Rao D. 1997. MIRD cellular S values. Reston (VA): Society of Nuclear Medicine.
   Google Scholar
• Hindorf C, Emfietzoglou D, Lindén O, Kostarelos K, Strand S-E. 2005. Internal microdosimetry for single cells in radioimmunotherapy of B-cell lymphoma. Cancer Biother Radiopharm. 20(2):224–230.
   PubMed Web of Science ®Google Scholar
• Hindorf C, Emfietzoglou D, Linden O, Bousis C, Fotopoulos A, Kostarelos K, Flux G. 2007. Single-cell dosimetry for radioimmunotherapy of B-cell lymphoma patients with special reference to leukemic spread. Cancer Biother Radiopharm. 22(3):357–366.
   PubMed Web of Science ®Google Scholar
• Howell RW. 2008. Auger processes in the 21st century. Int J Radiat Biol. 84(12):959–967.
   PubMed Web of Science ®Google Scholar
• Howell RW. 1992. Radiation spectrum for Auger-electron emitting radionuclides: report no. 2 of AAPM Nuclear Medicine Task Group No. 6. Med Phys. 19(6):1371–1383.
   PubMed Web of Science ®Google Scholar
• Humm JL, Charlton DE. 1989. A new calculational method to assess the therapeutic potential of Auger electron emission. Int J Radiat Oncol Biol Phys. 17(2):351–360.
   PubMed Web of Science ®Google Scholar
• Incerti S, Ivanchenko A, Karamitros M, Mantero A, Moretto P, Tran HN, Mas-Cialino B, Champion C, Ivanchenko VN, Bernal MA, et al. 2010. Comparison of GEANT4 very low energy cross section models with experimental data in water. Med Phys. 37:46–92.
   Web of Science ®Google Scholar
• Incerti S, Kyriakou I, Bernal MA, Bordage MC, Francis Z, Guatelli S, Ivanchenko V, Karamitros M, Lampe N, Lee SB, et al. 2018. Geant4-DNA example applications for track structure simulations in liquid water: a report from the Geant4-DNA Project. Med Phys. 45:722–739.
   Web of Science ®Google Scholar
• Joiner M, Kogel A. 2009. Basic clinical radiobiology. 4th ed. UK: Edward Arnold.
   Google Scholar
• Josefsson A. 2014. Microdosimetry of radiohalogens in thyroid models. Gothenburg, Sweden: Department of Radiation Physics, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg.
   Google Scholar
• Kassis A. 2004. The amazing world of Auger electrons. Int J Radiat Biol. 80(11–12):789–803.
   PubMed Web of Science ®Google Scholar
• Kassis A, Adelstein S. 2005. Radiobiologic principles in radionuclide therapy. J Nucl Med. 46:4S–12S.
   PubMed Web of Science ®Google Scholar
• Khan FM. 2007. Treatment planning in radiation oncology. 2nd ed. Baltimore: Lippincott Williams & Wilkins.
   Google Scholar
• Kyriakou I, Emfietzoglou D, Ivanchenko V, Bordage MC, Guatelli S, Lazarakis P, Tran HN, Incerti S. 2017. Microdosimetry of electrons in liquid water using the low-energy models of Geant4. J Appl Phys. 122(2):024303.
   Web of Science ®Google Scholar
• Kyriakou I, Incerti S, Francis Z. 2015. Technical note: improvements in GEANT4 energy-loss model and the effect on low energy electron transport in liquid water. Med Phys. 42(7):3870–3876.
   PubMed Web of Science ®Google Scholar
• Kyriakou I, Sefl M, Nourry V, Incerti S. 2016. The impact of new Geant4-DNA cross section models on electron track structure simulations in liquid water. J Appl Phys. 119(19):194902.
   Web of Science ®Google Scholar
• Lampe N, Karamitros M, Breton V, Brown J, Kyriakou I, Sakata D, Sarramia D, Incerti S. 2018. Mechanistic DNA damage simulations in Geant4-DNA part 1: a parameter study in a simplified geometry. Phys Med. 48:135–145.
   PubMed Web of Science ®Google Scholar
• Lazarakis P, Incerti S, Ivanchenko V, Kyriakou I, Emfietzoglou D, Corde S, Rosenfeld AB, Lerch M, Tehei M, Guatelli S. 2018. Investigation of track structure and condensed history physics models for applications in radiation dosimetry on a micro and nano scale in Geant4. Biomed Phys Eng Express. 4(2):024001.
   Web of Science ®Google Scholar
• LeMotte PK, Little JB. 1984. DNA damage induced in human diploid cells by decay of incorporated radionuclides. Cancer Res. 44(4):1337–1342.
   PubMed Web of Science ®Google Scholar
• Nikjoo H, Emfietzoglou D, Charlton DE. 2008. The Auger effect in physical and biological research. Int J Radiat Biol. 84(12):1011–1026.
   PubMed Web of Science ®Google Scholar
• Nikjoo H, Goodhead DT, Charlton DE, Paretzke HG. 1989. Energy deposition in small cylindrical targets by ultrasoft X-rays. Phys Med Biol. 34(6):691–705.
   PubMed Web of Science ®Google Scholar
• Pomplun E. 1992. 123I: calculation of the Auger electron spectrum and assessment of the strand breakage efficiency. AAPM Symposium Series No. 8. p. 121–136.
   Google Scholar
• Pool SE, Krenning EP, Koning GA, van Eijck CHJ, Teunissen JJM, Kam B, Valkema R, Kwekkeboom DJ, de Jong M. 2010. Preclinical and clinical studies of peptide receptor radionuclide therapy. Semin Nucl Med. 40(3):209–218.
   PubMed Web of Science ®Google Scholar
• Raisali G, Mirzakhanian L, Masoudi SF, Semsarha F. 2013. Calculation of DNA strand breaks due to direct and indirect effects of Auger electrons from incorporated 123 I and 125 I radionuclides using the Geant4 computer code. Int J Radiat Biol. 89(1):57–64.
   PubMed Web of Science ®Google Scholar
• Rebischung C, Hoffmann D, Stefani L, Desruet MD, Wang K, Adelstein SJ, Artignan X, Vincent F, Gauchez AS, Zhang H, et al. 2008. First human treatment of resistant neoplastic meningitis by intrathecal administration of MTX plus (125)IUdR. Int J Radiat Biol. 84(12):1123–1129.
   PubMed Web of Science ®Google Scholar
• Roeske JL, Aydogan B, Bardies M, Humm JL. 2008. Small-scale dosimetry: challenges and future directions. Semin Nucl Med. 38:67–83.
   PubMed Web of Science ®Google Scholar
• Roots R, Kraft G, Gosschalk E. 1985. The formation of radiation-induced DNA breaks: the ratio of double-strand breaks to single-strand breaks. Int J Radiat Oncol Biol Phys. 11(2):259–265.
   PubMed Web of Science ®Google Scholar
• Sakata D, Lampe N, Karamitros M, Kyriakou I, Belov O, Bernal MA, Bolst D, Bordage MC, Breton V, Brown J, et al. 2019. Evaluation of early radiation DNA damage in a fractal cell nucleus model using Geant4-DNA. Phys Med. 62:152–157.
   PubMed Web of Science ®Google Scholar
• Salim R, Taherparvar P. 2019. Monte Carlo single-cell dosimetry using Geant4-DNA: the effects of cell nucleus displacement and rotation on cellular S value. Radiat Environ Biophys. 58(3):353–371.
   PubMed Web of Science ®Google Scholar
• Sefl M, Incerti S, Papamichael G, Emfietzoglou D. 2015. Calculation of cellular S-values using Geant4-DNA: the effect of cell geometry. Appl Radiat Isot. 104:113–123.
   PubMed Web of Science ®Google Scholar
• Seifi M, Shirani B. 2018. Micro-dosimetry calculation of Auger-electron emitting radionuclides mostly used in nuclear medicine using GEANT4-DNA. Appl Radiat Isot. 141:73–79.
   PubMed Web of Science ®Google Scholar
• Semsarha F, Raisali GR, Goliaei B, Khalafi H. 2015. Study of strand breaks induced by direct effects of monoenergetic electrons in B conformation of genetic material of living cells by using Geant4. J Nucl Sci Technol. 71:51–59.
   Google Scholar
• Stepanek J, Larsson B, Weinrei R. 1996. Auger-electron spectra of radionuclides for therapy and diagnostic. Acta Oncol. 35(7):863–868.
   PubMed Web of Science ®Google Scholar
• Stigbrand T, Carlsson J, Adams G. 2008. Targeted radionuclide tumor therapy. Dordrecht, Netherlands: Springer.
   Google Scholar
• Tounekti O, Kenani A, Foray N, Orlowski S, Mir LM. 2001. The ratio of single- to double-strand DNA breaks and their absolute values determine cell death pathway. Br J Cancer. 84(9):1272–1279.
   PubMed Web of Science ®Google Scholar
• Vallis KA, Reilly RM, Scollard D, Merante P, Brade A, Velauthapillai S, Caldwell C, Chan I, Freeman M, Lockwood G, et al. 2014. Phase I trial to evaluate the tumor and normal tissue uptake, radiation dosimetry and safety of (111)In-DTPA-human epidermal growth factor in patients with metastatic EGFR-positive breast cancer. Am J Nucl Med Mol Imaging. 4(2):181–192.
   PubMedGoogle Scholar