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Original Article

Manipulation of the Radiosensitivity of Pig Epidermis by Changing the Concentration of Oxygen and Halothane in the Anaesthetic Gas Mixture

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Pages 1023-1032 | Received 15 Feb 1989, Accepted 15 Jul 1989, Published online: 03 Jul 2009

References

  • van den Aardweg G.J.M.J., Hopewell J.W., Simmonds R.H. Repair and recovery in the epithelial and vascular connective tissues of pig skin after irradiation. Radiotherapy and Oncology 1988; 11: 73–82
  • van den Aardweg G.J.M.J., Hopewell J.W., Barnes D.W.H., Sansom J.M., Nethersell A.B.W. Modification of the radiation response of pig skin by manipulation of tissue oxygen tension using anaesthetics and administration of BW12C. International Journal of Radiation Oncology, Biology and Physics 1989; 16: 1191–1194
  • Adams G.E., Barnes D., duBoulay C., Loutit J.F., Cole S., Sheldon P.W., Stratford I.J., van den Aardweg G.J.M.J., Hopewell J.W., White R.D., Kneen G., Nethersell A.B.W., Edwards J.C. Induction of hypoxia in normal and malignant tissues by changing the oxygen affinity of hemoglobin—implications for therapy. International Journal of Radiation Oncology, Biology and Physics 1986; 12: 1299–1302
  • Algotsson L., Messeter K., Nordstrom C.H., Ryding E. Cerebral blood flow and oxygen consumption during isoflurane and halothane anesthesia in man. Acta Anaesthesiologica Scandinavica 1988; 32: 15–20
  • Alper T., Hornsey S. The effect of hypoxia during irradiation on four-day death in mice given single and split doses of electrons. British Journal of Radiology 1968; 41: 375–380
  • Bachofen M., Gage A., Bachofen H. Vascular response to changes in blood oxygen tension under various blood flow rates. American Journal of Physiology 1971; 220: 1786–1792
  • Bollen B., Tinker J., Hermsmeyer K. Halothane relaxes previously constricted isolated porcine coronary artery segments more than isoflurane. Anesthesiology 1987; 66: 748–752
  • van den Brenk H.A.S., Kerr R.C., Richter W., Papworth M.P. Enhancement of radiosensitivity of skin of patients by high pressure oxygen. British Journal of Radiology 1965; 38: 857–864
  • Cater D.B., Silver I.A. Quantitative measurements of oxygen tension in normal tissues and in the tumours of patients before and after radiotherapy. Acta Radiologica 1960; 53: 233–256
  • Churchill-Davidson I., Sanger C., Thomlinson R.H. Oxygenation in radiotherapy. II. Clinical application. British Journal of Radiology 1957; 30: 406–422
  • Davidson G.M. Peripheral blood flow during anaesthesia. Australian and New Zealand Journal of Surgery 1961; 31: 29–39
  • Denekamp J., Fowler J.F. Further investigations of the response of irradiated mouse skin. International Journal of Radiation Biology 1966; 10: 435–441
  • Denekamp J., Michael B.D., Rojas A., Stewart F.A. Thiol radioprotection in vivo: the critical role of tissue oxygen concentration. British Journal of Radiology 1981; 54: 1112–1114
  • Dische S., Anderson P.J., Sealy R., Watson E.R. Carcinoma of the cervix—anaemia, radiotherapy and hyperbaric oxygen. British Journal of Radiology 1983; 56: 251–255
  • Donavan W.E. Experimental models in skin flap research. Skin Flaps, W.C. Grabb, M.B. Myers. Little Brown, Boston 1975; 11–20
  • Down J.D., Collis C., Jeffrey P.K., Steel G.G. The effects of anaesthetics and misonidazole on the development of radiation-induced lung damage in mice. International Journal of Radiation Oncology, Biology and Physics 1983; 9: 221–226
  • Eger E.I. Isoflurane: A review. Anesthesiology 1981; 55: 559–576
  • Fowler J.F., Morgan R.L., Silvester J.A., Bewley D.K., Turner B.A. Experiments with fractionated X-ray treatment of the skin of pigs. I. Fractionation up to 28 days. British Journal of Radiology 1963; 36: 188–196
  • Fowler J.F., Bewley D.K., Morgan R.L., Silvester J.A. Experiments with fractioned x-irradiation of the skin of pigs. II. Fractionation up to five days. British Journal of Radiology 1965 a; 38: 278–284
  • Fowler J.F., Kragt K., Ellis R.E., Lindop P., Berry R.J. The effect of divided doses of 15 MeV electrons on the skin response of mice. International Journal of Radiation Biology 1965 b; 9: 241–252
  • Gelman S., Fowler K.C., Smith L.R. Regional blood flow during isoflurane and halothane anesthesia. Anesthesia, Analgesia 1984; 63: 557–565
  • Gilbert M., Roberts S.L., Mori M., Blomberg R., Tinker J.H. Comparative coronary vascular reactivity and hemodynamics during halothane and isoflurane anesthesia in swine. Anesthesiology 1988; 68: 243–253
  • Gillman M.A. Haematological changes caused by nitrous oxide. Cause for concern?. British Journal of Anaesthesia 1987; 59: 143–145
  • Hendry J.H. Radionecrosis of normal tissues: studies on mouse tails. International Journal of Radiation Biology 1978; 33: 47–55
  • Hendry J.H. Quantitation of the radiotherapeutic importance of naturally-hypoxic normal tissues from collated experiments with rodents using single doses. International Journal of Radiation Oncology, Biology and Physics 1979; 5: 971–976
  • Hickey R.F., Sybert P.E., Verrier E.D., Cason B.S. Effects of halothane, enflurane, and isoflurane on coronary blood flow autoregulation and coronary vascular reserve in the canine heart. Anesthesiology 1988; 68: 21–30
  • Hopewell J.W., van den Aardweg G.J.M.J. Radiobiological studies with pig skin. International Journal of Radiation Oncology, Biology and Physics 1988; 14: 1047–1050
  • Hornsey S., Myers R., Andreozzi U. Differences in the effects of anaesthesia on hypoxia in normal tissues. International Journal of Radiation Biology 1977; 32: 609–612
  • Jamieson D., van den Brenk H.A.S. Effect of progressive changes in body temperature of rats on tissue oxygen-tension, in relation to radiosensitivity. International Journal of Radiation Biology 1963 a; 6: 529–540
  • Jamieson D., van den Brenk H.A.S. Comparison of oxygen tension in normal tissues and yoshida sarcoma of the rat breathing air or oxygen at 4 atmospheres. British Journal of Cancer 1963 b; 17: 70–78
  • Keizer H.J., van Putten L.M. The radioprotective action on bone marrow CFU during immobilization of mice. Radiation Research 1976; 66: 326–336
  • Lanza V., Mercadante S., Pignataro A. Effects of halothane, enflurane, and nitrous oxide on oxyhemoglobin affinity. Anesthesiology 1988; 68: 591–594
  • McDowell D.G., Harper A.M. Blood flow and oxygen uptake of the cerebral cortex of the dog during anaesthesia with different volatile agents. Acta Neurologica Scandinavica 1965; 41(14)146–146
  • Meyn R.E., Jenkins W.T. Variations in normal and tumor sensitivity of mice to ionizing radiation-induced DNA strand breaks in vivo. Cancer Research 1983; 43: 5668–5673
  • Muldoon S.M., Hart J.L., Bowen K.A., Freas W. Attenuation of endothelium-mediated vasodilation by halothane. Anesthesiology 1988; 68: 31–37
  • Nunn J.F., Sharer N.M., Gorchein A., Jones J.A., Wickramasinghe S.N. Megaloblastic haemopoiesis after multiple short-term exposure to nitrous oxide. Lancet 1982; 1: 1379–1381
  • Pauca A.L., Hopkins A.M. Acute effects of halothane, nitrous oxide and thiopentone on the upper limb blood flow. British Journal of Anaesthesia 1971; 43: 326–333
  • Sahlman L., Hendriksson B.A., Martner J., Ricksten S.E. Effects of halothane, enflurane, and isoflurane on coronary vascular tone, myocardial performance, and oxygen consumption during controlled changes in aortic and left atrial pressure. Anesthesiology 1988; 69: 1–10
  • Sakabe T., Kuramoto T., Kumagae S., Takeshita H. Cerebral responses to the addition of nitrous oxide to halothane in man. British Journal of Anaesthesia 1976; 48: 957–962
  • Sessler D.I., Olofsson C.I., Rubinstein E.H., Beebe J.J. The thermoregulatory threshold in humans during halothane anesthesia. Anesthesiology 1988; 68: 836–842
  • Seyde W.C., Ellis J.E., Longnecker D.E. The addition of nitrous oxide to halothane decreases renal and splanchnic flow and increases cerebral blood flow in rats. British Journal of Anaesthesia 1986; 58: 63–68
  • Seyde W.C., Longnecker D.E. Anesthetic influences on regional hemodynamics in normal and hemorrhaged rats. Anesthesiology 1984; 61: 686–698
  • Siemann D.W., Hill R.P., Penney D.P. Early and late pulmonary toxicity in mice evaluated 180 and 240 days following localized lung irradiation. Radiation Research 1982; 89: 396–407
  • Spiss C.K., Smith C.M., Tsujimoto G., Hoffman B.B., Maze M. Prolonged hyporesponsiveness of vascular smooth muscle contraction after halothane anesthesia in rabbits. Anesthesia, Analgscia 1985; 64: 1–6
  • Sprague D.H., Yang J.C., Ngai S.H. Effects of isoflurane and halothane on contractility and the cyclic 3′, 5′-adenosine monophosfate system in the rat aorta. Anesthesiology 1974; 40: 162–167
  • Steel G.G., Adams K., Peckham M.J. Lung damage in C57BL mice following thoracic irradiation: enhancement by chemotherapy. British Journal of Radiology 1979; 52: 741–747
  • Travis E.L., Parkins C.S., Holmes S.J., Down J.D. Effect of misonidazole and radiation injury to mouse spinal cord. British Journal of Cancer 1982; 45: 469–473
  • Winters G.D. Epidermal regeneration studies in the domestic pig. Epidermal Wound Healing, H.E. Maibach, D.T. Rovee. Year Book Medical Publishers, Chicago 1972; 71–112
  • Withers H.R. The effect of oxygen and anaesthesia on radiosensitivity in vivo of epithelial cells of mouse skin. British Journal of Radiology 1967; 40: 335–343
  • Young C.M.A. Functional and morphological changes in the dermis of pig skin following surgery or X-irradiation. Oxford 1978, D.Phil. thesis
  • Young C.M.A., Hopewell J.W. Functional and morphological changes in pig skin after single or fractionated doses of X-rays. International Journal of Radiation Oncology, Biology and Physics 1982; 8: 1539–1547
  • Yuhas J.M. Misonidazole enhancement of acute and late radiation injury to the rat spinal cord. British Journal of Cancer 1979; 40: 161–163

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