17
Views
39
CrossRef citations to date
0
Altmetric
Original Article

DNA Organization Affects Cellular Radiosensitivity and Detection of Initial DNA Strand Breaks

Pages 389-396 | Received 12 Feb 1992, Accepted 20 Apr 1992, Published online: 03 Jul 2009

References

  • Adachi Y., Käs E., Laemmli U.K. Preferential, cooperative binding of DNA topoisomerase II to scaffold-associated regions. EMBO Journal 1989; 8: 3997–4006
  • Ahnström G., Erixon K. Radiation-induced single-strand breaks in DNA determined by rate of alkaline strand separation and hydroxylapatite chromatography: an alternate to velocity sedimentation. International Journal of Radation Biology 1973; 36: 197–199
  • Ahnström G. Techniques to measure DNA single-strand breaks in cells: a review. International Journal of Radiation Biology 1988; 54: 695–707
  • Ben-Ze'ev A. Animal cell shape changes and gene expression. BioEssays 1991; 13: 207–211
  • Bodnar J.W., Jones C.J., Coombs D.H., Pearson G.D., Ward D.C. Proteins tightly bound to DNA at nuclear matrix attachment sites. Molecular and Cellular Biology 1983; 3: 1567–1567
  • Bohr V.A., Phillips D.H., Hanawalt P.C. Heterogeneous DNA damage and repair in the mammalian genome. Cancer Research 1987; 47: 6426–6436
  • Bradley M.O., Kohn D.W. X-ray induced DNA double-strand break production and repair in mammalian cells as measured by neutral filter elution. Nucleic Acids Research 1979; 7: 793–804
  • Chiu S.M., Oleinick N.L., Friedman L.R., Stambrook P.J. Hypersensitivity of DNA in transcriptionally active chromatin to ionizing radiation. Biochemica et Biophysica Acta 1982; 699: 15–21
  • Chiu S.M., Xue L., Friedman L.R., Oleinick N.L. Chromatin compaction and the efficiency of formation of DNA-protein crosslinks in γ-irradiated mammalian cells. Radiation Research 1992; 129: 184–191
  • Cook P.R. Hypothesis on differentiation and the inheritance of gene superstructure. Nature 1973; 245: 23–25
  • Cook P.R., Brazell I.A. Supercoils in human DNA. Journal of Cell Science 1975; 19: 261–279
  • Cook P.R. The nucleoskeleton: artefact, passive framework or active site?. Journal of Cell Science 1988; 90: 1–6
  • Cress A.E., Kurath K.M., Stea B., Bowden G.T. The crosslinking of nuclear protein to DNA using ionizing radiation. Journal of Cancer Research and Clinical Oncology 1991; 116: 324–330
  • de Jong L., van Driel R., Stuurman N., Meijne M.L., van Renswoude J. Principles of nuclear organization. Cell Biology International Reports 1990; 14: 1051–1074
  • Durand R.E., Sutherland R.M. Effects of intercellular contact on repair of radiation damage. Experimental Cell Research 1972; 71: 75–80
  • Durand R.E., Olive P.L. Radiation-induced DNA damage in V79 spheroids and monolayers. Radiation Research 1981; 78: 50–60
  • Elkind M.M. Damage-repair studies of the DNA from X-irradiated Chinese hamster cells. Molecular Mechanisms for Repair of DNA, Part B, P.C. Hanawalt, R.B. Setlow. Plenum Press, New York 1974; 689–698, In
  • Folkman J., Moscona A. Role of cell shape in growth control. Nature 1978; 273: 345–349
  • Fox M.H., Arndt-Jovin D.J., Jovin T.M., Baumann P.H., Robert-Nicoud M. Spatial and temporal distribution of DNA replication sites localized by immunofluorescence and confocal microscopy in mouse fibroblasts. Journal of Cell Science 1991; 99: 247–253
  • George A.M., Cramp W.A. The effects of ionizing radiation on structure and function of DNA. Progress on Biophysics and Molecular Biology 1987; 50: 121–169
  • Gordon D.J., Milner A.W., Beaney R.P., Gridina D.J., Vaughan A.T.M. The increase in radioresistance of V79 cells cultured as spheroids is correlated to changes in nuclear morphology. Radiation Research 1990; 121: 174–179
  • Iliakis G. The role of DNA double-strand breaks in ionizing radiation-induced killing of eukaryotic cells. BioEssays 1991; 13: 641–648
  • Iliakis G., Okayasu R., Seaner R. Radiosensitive xrs-5 and parental CHO cells show identical DNA neutral filter elution dose-response: implications for a relationship between cell radiosensitivity and induction of DNA double-strand breaks. International Journal of Radiation Biology 1988; 54: 55–62
  • Kapiszewska M., Wright W.D., Lange C.S., Roti Roti J.L. DNA supercoiling changes in nucleoids from irradiated L5178Y-S and -R cells. Radiation Research 1989; 119: 569–575
  • Kaufmann S.H., Fields A.P., Shaper J.H. The nuclear matrix: current concepts and unanswered questions. Methods and Achievements in Experimental Pathology. Karger, Basel 1986; 12: 141–171, In
  • Kelland L.R., Edwards S.M., Steel G.G. Induction and rejoining of DNA double-strand breaks in human cervix carcinoma cell lines of differing radiosensitivity. Radiation Research 1988; 116: 526–538
  • Klymkowski M.W., Bachant J.B., Domingo A. Functions of intermediate filaments. Cell Motility and the Cytoskeleton 1989; 14: 309–331
  • Lipetz P.D., Gaisky A.G., Stephens R.E. Relationship of DNA tertiary and quaternary structure to carcinogenic processes. Advances in Cancer Research 1982; 36: 165–210
  • Ljungman M., Nyberg S., Nygren J., Eriksson M., Ahnström G. DNA-bound proteins contribute much more than soluble intracellular compounds to the intrinsic protection against radiation-induced DNA strand breaks in human cells. Radiation Research 1991; 127: 171–176
  • Milner A.E., Vaughan A.T.M., Clark I.P. Measurement of DNA damage in mammalian cells using flow cytometry. Radiation Research 1987; 110: 108–117
  • Mirkovitch J., Mirault M., Laemmli J.K. Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold. Cell 1984; 39: 223–232
  • Mullenders L.H.F., Venema J., Mayne L., Natarajan A.T., van Zeeland A.A. Non-random distribution of UV-induced repair in higher-order chromatin loops in human cells and its relationship to preferential repair of active genes. DNA Repair Mechanisms and Their Biological Implications in Mammalian Cells, M.W. Lambert, J. Laval. Plenum Press, NY 1988; 339–348, In
  • Nakamura H., Morita T., Sato C. Structural organizations of replicon domains during DNA synthetic phase in the mammalian nucleus. Experimental Cell Research 1986; 165: 291–297
  • Okayasu R., Blöcher D., Iliasis G. Variation through the cell cycle in the dose-response of DNA neutral filter elution in X-irradiated synchronous CHO cells. International Journal of Radiation Biology 1988; 53: 729–747
  • Olive P.L., Hilton J., Durand R.E. DNA conformation of Chinese hamster V79 cells and senstivity to ionizing radiation. Radiation Research 1986; 107: 115–124
  • Olive P.L. DNA precipitation assay: a rapid and simple method for detecting DNA damage in mammalian cells. Environmental and Molecular Mutagenesis 1988; 11: 487–495
  • Olive P.L. Cell proliferation as a requirement for development of the contact effect in Chinese hamster V79 spheroids. Radiation Research 1989; 117: 79–92
  • Olive P.L., Vanderbyl S., MacPhail S.H. Resistance to DNA denaturation in irradiated Chinese hamster V79 fibroblasts is linked to cell shape. Experimental Cell Research 1991a; 193: 330–345
  • Olive P.L., Wlodek D., Banath J.P. DNA double-strand breaks measured in individual cells subjected to gel electrophoresis. Cancer Research 1991b; 51: 4671–4676
  • Olive P.L., Banath J.P., Durand R.E., Evans H.H. Etoposide sensitivity and topoisomerase II activity in Chinese hamster V79 monolayers and small spheroids. International Journal of Radiation Biology 1991c; 60: 453–466
  • Olive P.L., MacPhail S.H. Radiation-induced DNA unwinding is influenced by cell shape and trypsin. Radiation Research 1992; 130: 241–248
  • Osheroff N. Biochemical basis for the interactions of type I and type II topoisomerases with DNA. Pharmacology and Therapeutics 1989; 41: 223–241
  • Painter R.B., Young B.R. Formation of nascent DNA molecules during inhibition of replicon initiation in mammalian cells. Biochemica Biophysica Acta 1976; 418: 146–253
  • Penman S. If genes just make proteins and our proteins are the same, then why are we so different?. Journal of Cell Biochemistry 1991; 47: 95–98
  • Pienta K.J., Partin A.W., Coffey D.S. Cancer as a disease of DNA organization and dynamic cell structure. Cancer Research 1989; 49: 2525–2532
  • Radford I.R. The level of induced DNA double-strand breakage correlates with cell killing after X-irradiation. International Journal of Radiation Biology 1985; 48: 45–54
  • Radford I.R. Use of ‘nuclear monolayers’ to identify factors influencing DNA double-strand breakage by X-rays. International Journal of Radiation Biology 1987; 52: 555–563
  • Radford I.R., Hodgson G.S. A comparison of the induction of DNA double-strand breakage and lethal lesions by X-irradiation in Ataxia telangiectasia and normal fibroblasts. Radiation Research 1990; 124: 334–335
  • Roti Roti J.L., Wright W.D. Visualization of DNA loops in nucleoids from HeLa cells: assays for DNA damage and repair. Cytometry 1987; 8: 461–467
  • Sapora O., Belli M., Maione B., Pazzaglia S., Tabocchini M.A. The influence of genome structural organization on DNA damage and repair in eukaryotic cells exposed to ionizing radiation. NATO ASI Series, Vol. H54, The Early Effects of Radiation on DNA, E.M. Fielden, P. O'Neill. Springer-Verlag, Berlin 1991, In
  • Schwartz J.L., Vaughan A.T.M. Association among DNA/chromosome break rejoining rates, chromatin structure alterations and radiation sensitivity in human tumor cell lines. Cancer Research 1989; 49: 5054–5057
  • Schwartz J.L., Mustafi R., Beckett M.A., Czyzewski E.A., Farhangi E., Gridina D.J., Rotmensch J., Weichselbaum R.R. Radiation-induced DNA double-strand break frequencies in human squamous cell carcinoma cell lines of different radiation sensitivities. International Journal of Radiation Biology 1991; 59: 1341–1352
  • Smerdon M.J. DNA Repair and the role of chromatin structure. Current Opinion in Cell Biology 1991; 3: 422–428
  • Smith P.J. DNA topoisomerases and radiation responses. International Journal of Radiation Biology 1990; 58: 553–559
  • Stamato T.D., Denko N. Asymmetric filed inversion gel electrophoresis: a new method for detecting DNA double-strand breaks in mammalian cells. Radiation Research 1990; 121: 196–205
  • Sweigert S.E., Rowley R., Warters R.L., Dethlefsen L.A. Cell cycle effect on the induction of DNA double-strand breaks by X-rays. Radiation Research 1988; 116: 228–244
  • Taylor Y.C., Duncan P.G., Zhang X., Wright W.D. Differences in the DNA supercoiling response of irradiated cell lines from ataxia-telangiectasia versus unaffected individuals. International Journal of Radiation Biology 1991a; 59: 359–371
  • Taylor Y.C., Zhang X., Parsian Z.J., Dungan P.G. Image analysis-based measurement of DNA supercoiling changes in transformed and nontransformed human cell lines. Experimental Cell Research 1991b; 197: 222–228
  • Vaughan A.T.M., Milner A.M., Gordon D.G., Schwartz J.L. Interaction between ionizing radiation and supercoiled DNA within human tumor cells. Cancer Research 1991; 51: 3857–3861
  • Ward J.F. The yield of DNA double-strand breaks produced intracellularly by ionizing radiation: a review. International Journal of Radiation Biology 1990; 57: 114–1150
  • Warters R.L., Lyons B.W. Detection of ionizing radiation-induced DNA double-strand breaks by filter elution is affected by nuclear chromatin structure. Radiation Research 1990; 124: 309–316
  • Wlodek D., Hittelman W.N. The repair of double-strand breaks correlates with radiosensitivity of L5178Y-S and L5178Y-R cells. Radiation Research 1987; 112: 146–155
  • Wlodek D., Olive P.L. Physical basis for detection of DNA double-strand breaks using neutral filter elution. Radiation Research 1990; 124: 326–333
  • Wlodek D., Olive P.L. Neutral filter elution detects differences in chromatin organization which can influence cellular radiosensitivity. Radiation Research 1992, in press
  • Wlodek D., Banath J., Olive P.L. Comparison between pulsed-field and constant-field gel electrophoresis for measurement of DNA double-strand breaks in irradiated CHO cells. International Journal of Radiation Biology 1991; 60: 779–790
  • Yasui L., Ling-Indeck L., Johnson-Wint B., Fink T.J., Molsen D. Changes in the nuclear structure in the radiation-sensitive CHO mutant, xrs-5. Radiation Research 1991; 127: 269–277
  • Yatvin M.B., Yukawa O., Dennis W.H. Influence of membrane lipid composition and organization on radio- and thermosensitivity of bacteria. Prostaglandin and Lipid Metabolism in Radiation Injury, T.L. Walden, H.N. Hughes. Plenum Press, New York 1987; 45–57, In

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.