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Original Article

Does the Enzymatic Conversion of DNA Single-strand Damage into Double-strand Breaks Contribute to Biological Inactivation of γ-irradiated Plasmid DNA

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Pages 167-171 | Received 27 Apr 1992, Accepted 08 Sep 1992, Published online: 03 Jul 2009

References

  • Ahnström G., Bryant P.E. DNA double-strand breaks generated by the repair of X-ray damage in Chinese hamster cells. International Journal of Radiation Biology 1982; 41: 671–676
  • Bonura T., Smith K.C., Kaplan H.S. Enzymatic induction of DNA double-strand breaks in γ-irradiated Escherichia coli K-12. Proceedings of the National Academy of Sciences, USA 1975; 72: 4265–4269
  • Bresler S.E., Noskin L.A., Suslov A.V. Induction by gamma irradiation of double-strand breaks of Escherichia coli chromosomes and their role in cell lethality. Biophysical Journal 1984; 45: 749–754
  • Bryant P.E. Enzymatic restriction of mammalian cell DNA using Pvu II and Bam Hl: evidence of the double-strand break origin of chromosomal aberrations. International Journal of Radiation Biology 1984; 46: 57–65
  • Dikomey E. Induction and repair of DNA strand breaks in X-irradiated proliferating and quiescent CHO cells. International Journal of Radiation Biology 1990; 57: 1169–1182
  • Frankenberg D., Frankenberg-Schwager M., Blöcher D., Harbich R. Evidence for DNA double-strand breaks as the critical lesions in yeast cells irradiated with sparsely or densely ionizing radiation under oxic or anoxic conditions. Radiation Research 1981; 88: 524–532
  • Hartke A., Schulte-Frohlinde D. Survival of M13mp18 gapped duplex DNA as a function of gap length. Mutation Research 1991; 255: 39–48
  • Herskind C., Thacker J. Inactivation of DNA-mediated transformation of hamster cells by γ-rays and deoxyribonuclease I. Mutation Research 1988; 198: 169–178
  • Kaplan H.S. DNA-strand scission and loss of viability after X irradiation of normal and sensitized bacterial cells. Proceedings of the National Academy of Sciences, USA 1966; 55: 1442–1446
  • Klimczak U. Strangbrüche und letale Schäden in 60Co-γ-bestrahlter Plasmid-DNA. Ruhr-Universität Bochum. 1992, Thesis
  • Kohfeldt E., Bertram H., Hagen U. Action of gamma endonuclease on clustered lesions in irradiated DNA. Radiation and Environmental Biophysics 1988; 27: 123–132
  • Kow Y.W., Faundez G., Melamede R.J., Wallace S.S. Processing of model single-strand breaks in φ174 RF transfecting DNA by Escherichia coli. Radiation Research 1991; 126: 357–366
  • Lafleur M.V.M., Loman H. Radiation damage to φ174 DNA and biological effects. Radiation Environmental Biophysics 1986; 25: 197–200
  • Lu A.-L., Clark S., Modrich P. Methyl-directed repair of DNA base-pair mismatches in vitro. Proceedings of the National Academy of Sciences, USA 1983; 80: 4639–4643
  • Martin-Bertram H., Rumpf E., Winkler C. Evidence for radiation-induced bulky lesions in DNA. Radiation and Environmental Biophysics 1983; 21: 305–307
  • Moran E., Wallace S.S. The role of specific DNA base damages in the X-ray-induced inactivation of bacteriophage PM2. Mutation Research 1985; 146: 229–241
  • Preston R.J. Effect of cytosine-arabinoside on the frequency of X-ray induced chromosome aberrations in normal human-leucocytes. Mutation Research 1980; 69: 71–79
  • Radford I.R. The level of induced DNA double-strand breakage correlates with cell killing after X-irradiation. International Journal of Radiation Biology 1985; 48: 45–54
  • Sargentini N.J., Smith K.C. Characterization and quantitation of DNA strand breaks requiring recA-dependent repair in X-irradiated Escherichia coli. Radiation Research 1986; 105: 180–186
  • Schulte-Frohlinde D., Bothe E., Klimczak U., Ludwig D.C., Mark F., Rettberg P., Schünemann S., Ventur Y., Worm K.-H. Radiation-induced damage and biological inactivation of plasmid DNA in water-alcohol mixtures: what is the lethal damage?. Proceedings IOP Publishing, Padua, Italy Sept. 2–5 (1991). Hilger, New York 1992, Biophysical modelling of radiation effects
  • Van der Schans G.P., Bleichrodt J.F., Blok J. Contribution of various types of damage to inactivation of a biologically-active double-stranded circular DNA by gamma-radiation. International Journal of Radiation Biology 1973; 23: 133–150
  • Wake C.T., Gudewicz T., Porter T., White A., Wilson J.H. How damaged is the biologically active subpopulation of transfected DNA?. Molecular and Cellular Biology 1984; 4: 387–398
  • Waters L.C., Sikpi M.O., Preston R.J., Mitra S., Jaberaboansari A. Mutations induced by ionizing radiation in a plasmid replicated in human cells. Radiation Research 1991; 127: 190–201
  • Wheeler K.T., Nelson G.B. DNA repair kinetics in irradiated undifferentiated and terminally differentiated cells. Radiation and Environmental Biophysics 1983; 22: 3–19

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