Cloning Efficiency and Spontaneous Mutant Frequency in Circulating T-lymphocytes in Ataxia-telangiectasia Patients

References

• Arlett C.F., Priestley A. An assessment of the radiosensitivity of ataxia-telangiectasia heterozygotes. Ataxia-Telangiectasia: Genetics, Neuropathology, and Immunology of a Degenerative Disease of Childhood, R.A. Gatti, M. Swift. Liss, New York 1985; 101–110, In
   Google Scholar
• Arlett D.F., Green M.H.L., Priestley A., Harcourt S.A., Mayne L.M. Comparative human cellular radiosensitivity. I. The effect of SV40 transformation and immortalisation on the γ-irradiation survival of skin-derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes. International Journal of Radiation Biology 1988; 54: 911–928
   PubMed Web of Science ®Google Scholar
• Bigbee W.L., Langlois R.G., Swift M., Jensen R.H. Evidence for an elevated frequency of in vivo somatic cell mutations in ataxia-telangiectasia. American Journal of Human Genetics 1989; 44: 402–408
   PubMed Web of Science ®Google Scholar
• Borresen A., Anderson T.I., Tretli S., Helberg A., Moller P. Breast cancer and other cancers in Norweigan families with ataxia-telangiectasia. Genes, Chromosomes and Cancer 1990; 2: 339–340
   PubMed Web of Science ®Google Scholar
• Broughton B.C., Steingrimsdottir H., Weber C., Lehmann A.R. Mutations in the xeroderma pigmentosum group D DNA repair gene in patients with trichothiodystrophy. Nature Genetics 1994; 7: 189–193
   PubMed Web of Science ®Google Scholar
• Ataxia-Telangiectasia: A Cellular and Molecular Link Between Cancer, Neuropathology and Immune Deficiency, B.A. Bridges, D.G. Harnden. Wiley, London 1982
   Google Scholar
• Christopoulos G.C. The application of an improved micronucleus assay in the detection of ataxiatelangiectasia heterozygotes. University of Sussex. 1987, MPhil thesis
   Google Scholar
• Cole J., Arlett C.F., Green M.H.L., Harcourt S.A., Priestly A., Henderson L., Cole H., James S.E., Richmond F.R. Comparative human cellular readiosensitivity. II. The survival following gamma-irradiation of unstimulated (G0)T-lymphocytes, T-lymphocytes lines, lymphoblastoid cell lines and fibroblasts from normal donors, from ataxia-telangiectasia patients and from ataxia-telangiectasia heterozygotes. International Journal of Radiation Biology 1988b; 54: 929–943
   PubMed Web of Science ®Google Scholar
• Cole J., Arlett C.F., Green M.H.L., James S.E., Henderson L., Cole H., Sala-Trepat M., Benzi R., Price M.L., Bridges B.A. Measurement of mutant frequency to 6-thioguanine resistance in circulating T-lymphocytes for human population monitoring. New Trends in Genetic Risk Assessment, G. Jolles, A. Cordier. Academic, London 1989; 175–203, In
   Google Scholar
• Cole J., Arlett C.F., Green M.H.L., Norris P.G., Price M.L. An assessment of the circulating T-lymphocyte 6-thioguanine resistance system for population monitoring. Biomonitoring and Carcinogen Risk Assessment, R.C. Garner. Oxford University Press, Oxford 1991a, In
   Google Scholar
• Cole J., Arlett C.F., Norris P.G., Stephens G., Waugh A.P.W., Beare D.M., Green M.H.L. Elevated hrpt mutant frequency in circulating T-lymphocytes of xeroderma pigmentosum patients. Mutation Research 1992; 273: 171–178
   PubMedGoogle Scholar
• Cole J., Green M.H.L., James S.E., Henderson L., Cole H. Human population monitoring: a further assessment of factors influencing measurements of thioguanine-resistant mutant frequency in circulating T-lymphocytes. Mutation Research 1988a; 204: 493–507
   PubMedGoogle Scholar
• Cole J., Green M.H.L., Stephens G., Waugh A.P.W., Beare D., Steingrimsdottir H., Bridges B.A. HPRT Somatic mutation data. Mutation and the Environment. Part C. Somatic and Heritable Mutation, Adduction and Epidemiology, M.L. Mendelsohn, R.J. Albertini. Wiley-Liss, New York 1990; 25–35, In
   Google Scholar
• Cole J., Skopek T.R. ICPEMC Committee on spontaneous mutation: Working Paper 3: Somatic mutant frequency, mutation rates and mutational spectra in the human population. Mutation Research 1994; 304: 33–105
   PubMed Web of Science ®Google Scholar
• Cole J., Waugh A.P.W., Beare D.M., Sala-Trepat M., Stephens G., Green M.H.L. HPRT mutant frequencies in circulating lymphocytes: population studies using normal donors, exposed groups and cancer-prone syndromes. Trends in Biological Dosimetry, B.L. Gledhill, F. Mauro. Wiley, New York 1991b; 319–328, In
   Google Scholar
• Fiorilli M., Antonelli A., Russo G., Crescendi M., Carbonari M., Petrinelli P. Variant of ataxiatelangiectasia with low-level radiosensitivity. Human Genetics 1985; 70: 274–277
   PubMed Web of Science ®Google Scholar
• Ataxia-Telangiectasia: Genetics, Neuropathology, and Immunology of a Degenerative Disease of Childhood, R.A. Gatti, M. Swift. Liss, New York 1985
   Google Scholar
• Henderson L., Cole H., Cole J., James S.E., Green M.H.L. Detection of somatic mutations in man: evaluation of the microtiter cloning assay for T-lymphocytes. Mutagenesis 1986; 1: 195–200
   PubMed Web of Science ®Google Scholar
• Hoar D.I. Phenotypic manifestations of ataxiatelangiectasia. Lancet 1975; ii: 1048–1048
   Google Scholar
• Lehmann A.R., Arlett C.F., Burke J.F., Green M.H.L., James M.R., Lowe J.E. A derivative of an ataxia-telangiectasia (A-T) cell line with normal radiosensitivity but A-T-like inhibition of DNA synthesis. International Journal of Radiation Biology 1986; 49: 639–643
   Web of Science ®Google Scholar
• Jaspers N.G.J., Gatti R.A., Baan C., Linssen P.C.M.L., Bootsma D. Genetic complementation analysis of ataxia-telangiectasia and Nijmegen breakage syndrome: a survey of 50 patients. Cytogenetics and Cell Genetics 1988; 49: 259–263
   PubMedGoogle Scholar
• Jeggo P.A., Tesmer J., Chen D.J. Genetic analysis of ionizing radiation sensitive mutants of cultured mammalian cell lines. Mutation Research 1991; 254: 125–133
   PubMed Web of Science ®Google Scholar
• Nicklas J.A., Hunter T.C., O'Neill J.P., Albertini R.J. Molecular analyses of in vivo hprt mutations in human T-lymphocytes III. Longitudinal study of hprt structural alterations and T-cell clonal origins. Mutation Research 1989; 215: 147–160
   PubMedGoogle Scholar
• Pippard E.C., Hall A.J., Barker D.J.P., Bridges B.A. Cancer in homozygotes and heterozygotes of ataxia-telangiectasia and xeroderma pigmentosum in Britain. Cancer Research 1988; 48: 2929–2933
   PubMed Web of Science ®Google Scholar
• Robinson D.R., Goodall K., Albertini R.J., O'Neill J.P., Finette B., Sala-Trepat M., Moustacchi E., Tates A.D., Beare D.M., Green M.H.L., Cole J. An analysis of in vivo hprt mutant frequency in the normal population: a comparison of four data bases. Mutation Research 1994, in press
   PubMedGoogle Scholar
• Scott D., Jones L.A., Elyan S.A.G., Spreadborough A., Cowan R., Ribiero G. Identification of A-T heterozygotes. Ataxia-Telangiectasia, R.A. Gatti, R.B. Painter. Nato ASI Series, Springer, Berlin 1993; H77: 101–116, In
   Google Scholar
• Sedgwick R.P., Boder E. Ataxia-telangiectasia. Handbook of Clinical Neurology, Hereditary Neuropathies and Spinocerebellar Atrophies, J.M.B.V. de Jong. Elsevier, Amsterdam 1991; 16: 347–423, In
   Google Scholar
• Steingrimsdottir H., Rowley G., Waugh A., Beare D., Ceccherini I., Cole J., Lehmann A.R. Molecular analysis of mutations in the hprt gene in circulating lymphocytes from normal and DNA repairdeficient donors. Mutation Research 1993; 294: 29–41
   PubMedGoogle Scholar
• Swift M., Reitnauer P.J., Morrel D., Chase C.L. Breast and other cancers in families with ataxiatelangiectasia. New England Journal of ' Medicine 1987; 316: 1289–1294
   PubMed Web of Science ®Google Scholar
• Tanaka K. Analysis of DNA excision repair genes in XP. Frontiers of Photobiology, A. Shima, M. Ichahashi, Y. Fujiwara, H. Takebe. Excerpta Medica, Amsterdam 1993; 293–302, In
   Google Scholar
• Tates A.D., Bernini L.F., Natarajan A.T., Ploem J.S., Verwoerd N.P., Cole J., Green M.H.L., Arlett C.F., Norris P.N. Detection of somatic mutations in man: HPRT mutations in lymphocytes and hemoglobin mutations in erythrocytes. Mutation Research 1989; 213: 73–82
   PubMedGoogle Scholar
• Taylor A.M.R. Cytogenetics of ataxia-telangiectasia. Ataxia-Telangiectasia: A Cellular and Molecular Link between Cancer, Neuropathology and Immune Deficiency, B.A. Bridges, D.G. Harnden. Wiley, London 1982; 53–81, In
   Google Scholar
• Taylor A.M.R., Flude E., Laher B., Stacey M., McKay E., Watt J., Green S.H., Harding A.E. Variant forms of ataxia-telangiectasia. Journal of Medical Genetics 1987; 24: 669–677
   PubMed Web of Science ®Google Scholar
• Taylor A.M.R., McConville C.M., Woods C.G., Byrd P.J., Hernandez D. Clinical and cellular heterogeneity in ataxia-telangiectasia. Ataxia-Telangiectasia, R.A. Gatti, R.B. Painter. Nato ASI Series, Springer, Berlin 1993; H77: 209–231, In
   Google Scholar
• Thacker J., Wilkinson R.E. The genetic basis of resistance to ionising radiation damage in cultured mammalian cells. Mutation Research 1991; 254: 135–142
   PubMedGoogle Scholar
• Woods C.G., Bundey S.E., Taylor A.M.R. Unusual features in the inheritance of ataxia telangiectasia. Human Genetics 1990; 84: 555–562
   PubMed Web of Science ®Google Scholar