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Original Article

Radiation-induced Genomic Instability: Delayed Cytogenetic Aberrations and Apoptosis in Primary Human Bone Marrow Cells

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Pages 287-293 | Received 26 Sep 1994, Accepted 16 Nov 1994, Published online: 03 Jul 2009

References

  • Bender M.A., Awa A.A., Brooks A.L., Evans H.J., Groer P.G., Littlefield L.G., Pereira C., Preston R.J., Wacolz B.W. Current status of cytogenetic procedures to detect and quantify previous exposure to radiation. Mutation Research 1988; 196: 103–159
  • Born R., Trott K.R. Colonogenicity of the progeny of surviving cells after irradiation. International Journal of Radiation Biology 1988; 53: 319–330
  • Brown D.C., Trott K.R. Clonal heterogeneity in the progeny of HeLa cells which survive X-irradiation. International Journal of Radiation Biology 1994; 66: 151–155
  • Carrano A.V., Minkler J., Pilkso D. On the fate of stable chromosome aberrations. Mutation Research 1975; 30: 153–156
  • Elkind M.M., Sutton H. X-ray damage and recovery in mammalian cells in culture. Nature 1959; 184: 1293–1295
  • Evans E.P. Karyotyping and sexing of gametes, embryos and fetuses and in situ hybridization to chromosomes. Mammalian Development. A Practical Approach, M. Monk. IRL, Oxford University, Press. 1987; 93–114, In
  • Goodhead D.T. Spatial and temporal distribution of Energy. Health Physics 1988; 55: 231–240
  • Gorgojo L., Little J.B. Expression of lethal mutations in progeny of irradiated mammalian cells. International Journal of Radiation Biology 1989; 55: 619–630
  • Holmberg K., Falt S., Johansson A., Lambert B. Clonal chromosome aberrations and genomic instability in X-irradiated human T-lymphocyte cultures. Mutation Research 1993; 286: 321–330
  • Holyoake T.L., Freshney M.G., Konwalinka G., Haun M., Petzer A., Fitzsimmons E., Lucie N.P., Wright E.G., Pragnell I.B. Mixed colony formation in vitro by the heterogeneous compartment of multipotential progenitors in human bone marrow. Leukemia 1993; 7: 207–213
  • Kadhim M.A., Lorimore S.A., Hepburn M.D., Goodhead D.T., Buckle V.J., Wright E.G. Alphaparticle-induced chromosomal instability in human bone marrow cells. Lancet 1994; 344: 987–988
  • Kadhim M.A., Macdonald D.A., Goodhead D.T., Lorimore S.A., Marsden S.J., Wright E.G. Transmission of chromosomal instability after plutonium α-particle irradiation. Nature 1992; 355: 738–740
  • Khadim M.A., Lorimore S.A., Hepburn M.D., Goodhead D.T., Buckle V.J., Wright E.G. Alpha-particle-induced chromosomal instability in human bone marrow cells. Lancet 1994; 344: 987–988
  • Little J.B., Gorgojo L., Vetros H. Delayed appearance of lethal and specific gene mutations in irradiated mammalian cells. International Journal of Radiation Oncology, Biology and Physics 1990; 19: 1425–1429
  • Lorimore S.A., Goodhead D.T., Wright E.G. Inactivation of haemopoietic stem cells by slow alphaparticles. International Journal of Radiation Biology 1993; 63: 655–660
  • Marder B.A., Morgan W.F. Delayed chromosomal instability induced by DNA damage. Molecular and Cellular Biology 1993; 13: 6667–6677
  • Martins M.B., Sabatier L., Ricoul M., Pinton A., Dutrillaux B. Specific chromosome instability induced by heavy ions: a step towards transformation of human fibroblasts. Mutation Research 1993; 285: 229–237
  • Puck T.T., Marcus P.I. Action of X-rays on mammalian cells. Journal of Experimental Medicine 1956; 103: 653–666
  • Sabatier L., Dutrillaux B., Martin M.B. Chromosomal instability. Nature 1992; 357: 548–548
  • Seymour C.B., Mothersill C., Alper T. High yields of lethal mutations in somatic mammalian cells that survive ionizing radiation. International Journal of Radiation Biology 1986; 50: 167–179
  • Thompson L.H., Suit H.D. Proliferation kinetics of X-irradiated mouse L cells studies with time lapse photography. II. International Journal of Radiation Biology 1969; 15: 347–362
  • Trott K.R., Hug O. Intraclonal recovery of division probability in pedigrees of single X-irradiated mammalian cells. International Journal of Radiation Biology 1970; 17: 483–486

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