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Research Article

Alpha-particle-induced neoplastic transformation in synchronized hybrid cells of HeLa and human skin fibroblasts

Pages 523-529 | Published online: 03 Jul 2009

References

  • BALcEn-KumczEK, E. K. and HARRISON, G. H. 1991, Lack of dose-rate modification (0.0049 vs 042 Gy/min) of fission-neutron-induced neoplastic transformation in C3H10T1/2 Cells. International Journal of Radiation Biology, 59, 1017–1026.
  • BALCER-KUBICZEK, E. K., HARRISON, G. H., ZEMAN, G. H., MATTSON P. J. and KUNSKA, A., 1988, Lack of inverse dose-rate effect on fission neutron induced transformation of C3H10T1/2 cells. International Journal of Radiation Biology, 54, 531–536.
  • BETTEGA, D., CALZOLARI, P., COSTA, A., NORIS CHIORDA, G. and TALLONE, L., 1995, Oncogenic transformation of C3H10T1/2 cells exposed to alpha particles: sensitivity through the Cell Cycle. Radiation Research, 142, 276–280.
  • BETTEGA, D., CALZOLARI, P., NORIS-CHIORDA, G. and T ALLONE-LOMBARDI, L., 1992, Transformation of C3H10T1/2 cells with a particles at low doses: effects of single and fraction-ated doses. Radiation Research, 131, 66–71.
  • BRENNER, D. J. and HALL, E. J., 1990, The inverse dose rate effect for oncogenic transformation by neutrons and charged particles: a plausible interpretation consistent with published data. International J ournal of Radiation Biology, 58, 745–758.
  • BRENNER, D. J., HALL, E. J., RANDERS-PEHRSON G. and MILLER, R. C., 1993, Mechanistic consideration on the dose-rate/LET dependence of oncogenic transformation by ionising radiation. Radiation Research, 133, 365–369.
  • BURCH, P. R. and CHESTER, M. S., 1986, Neoplastic transforma-tion of cells in vitro at low and high dose-rates of fission neutrons: an interpretation. International Journal of Radiation Biology, 49, 495–500.
  • CAO, J., WELLS, R. L. and ELKIND, M. M., 1993, Neoplastic transformation of C3H mouse embryo cells, 10T1/ 2: cell cycle dependence for 50 kV X-rays and UV-B light. International Journal of Radiation Biology, 64, 83–92.
  • ELKIND, M. M., 1991, Enhancement of neoplastic transformation due to protracted exposure of fission spectrum neutrons: biophysical model. International Journal of Radiation Biology, 59, 1467–1475.
  • HIEBER, L., PONSEL, G., Roos, H., FEEN, S., FROMKE E. and KELLERER, A. M., 1987, Absence of dose-rate effect in the transformation of C3H10T1/2 cells by a-particles. International Journal of Radiation Biology, 52, 859–869.
  • HILL, C. K., BuoNAouRo, F. M., MYERS, C. P., HAN, A. and ELKIND, M. M., 1982, Fission-spectrum neutrons at reduced dose rates enhance neoplastic transformation. Nature, 298, 67–69.
  • HILL, C. K., CARNEs, B. A., HAN, A. and ELKIND, M. M., 1985, Neoplastic transformation is enhanced by multiple low doses of fission-spectrum neutrons. Radiation Research, 102, 404–410.
  • HILL, C. K., HAN, A. and ELKIND, M. M., 1984, Fission-spectrum neutrons at a low dose rate enhance neoplastic transformation in the linear, low dose region (0-10 cGy). International Journal of Radiation Biology, 46, 11–15.
  • JONES, C. A., SEDITA, B. A., HILL, C. K. and ELKIND, M. M., 1989, Influence of dose rate on transformation of Syrian hamster embryo cells by fission-spectrum neutrons. In Low Dose Radiation- biological Bases of Risk Assessment, edited by K. F. Baverstock and J. W. Stather (London: Taylor & Francis), pp. 539–546.
  • MENDONCA, M. S., ANTONIONO, R. J., SUN, C. and REDPATH, J. L., 1992, A simplified and rapid staining method for the HeLa X Skin fibroblast human hybrid cell neoplastic transformation assay. Radiation Research, 131, 345–350.
  • MILLER, R. C., BRENNER, D. J., GEARD, C. J., KOMATSU, C. R., MARINO, S. A. and HALL, E. J., 1988, Oncogenic trans-formation by fractionated doses of neutrons. Radiation Research, 114, 589–597.
  • MILLER, R. C., GEARD, C. R., GEARD, M. and HALL, E. J., 1992, Cell cycle dependent radiation-induced oncogenic transformation of C3H10T1/2 cells. Radiation Research, 130, 129–133.
  • MILLER, R. C., GEARD, C. R., MARTIN, S. G., MARINO S. A. and HALL, E. J., 1995, Neutron-induced cell cycle-dependent oncogenic transformation of C3H10T1/2 cells. Radiation Research, 142, 270–275.
  • MILLER, R. C., RANDERS-PEHRSON, G., HIEBER, L., MARINO, S. A., RICHARDS, M. and HALL, E. J., 1993, The inverse dose-rate effect for oncogenic transformation by charged particles is dependent on linear energy transfer. Radiation Research, 133, 360–364.
  • PAZZAGLIA, S., SARAN, A., PARISET, L., REBESSI, S., DI MAIO, V., COPPOLA, M. and COVELLI, V., 1996, Sensitivity of C3H10T1/2 cells to radiation-induced killing and neo-plastic transformations a function of cell cycle. International Journal of Radiation Biology, 69, 58–65.
  • REDPATH, J. L., ANTONIONO, R. J., SUN, C., GERSTENBERGAND, H. M. and BLAKELY, W. F., 1995, Late mitosis/early G1-phase and mid-G1-phase are not hypersensitive cell cycle phases for neoplastic transformation of HeLa X skin fibroblast human hybrid cells induced by fission-spectrum neutrons. Radiation Research, 141, 37–43.
  • REDPATH, J. L., HILL, C. K., JONES, C. A. and SUN, C., 1990, Fission-neutron-induced espression of a tumor- C. associ-ated antigen in human cell hybrids (HeLa X Skin fibroblasts): evidence for increased expression at low dose rate. International journal of Radiation Biology, 58, 673–680.
  • REDPATH, J. L. and SUN, C., 1990, Sensitivity of a human hybrid cell line (HeLa X skin fibroblast) to radiation-induced neoplastic transformation in G2, M, and G1 phases of the Cell Cycle. Radiation Research, 121, 206–211.
  • REDPATH, J. L., SUN, C. and BLAKELEY, W. F., 1991, Effect of fission-neutron dose rate -on the induction of a tumor-associated antigen in human cell hybrids (HeLa X Skin fib rob la sts). Radiation Research, 128, S71–S74 .
  • REDPATH, J. L., SUN, C., COLMAN, M. and STANBRIDGE, E. J.7 1987, Neoplastic transformation of human hybrid cells by radiation: a quantitative assay. Radiation Research, 110, 468–472.
  • ROSSI, H. J. and KETTERER, A. M., 1986, The dose rate dependence of oncogenic transformation by neutrons may be due to variation of response during the cell cycle. International journal of Radiation Biology, 50, 353–361.
  • SARAN, A., PAZZAGLIA, S., COPPOLA, M., REBESSI, S., DI MAJO, V., GARAVINI M. and COVELLI, V., 1991, Absence of dose-fractionation effect on neoplastic transformation induced by fission-spectrum neutrons in C3H10T1/2 cells. Radiation Research, 126, 343–348.
  • SARAN, A., PAZZAGLIA, S., PARISET, L., REBESSI, S., BROERSE, J. J., ZOETELIEF, J., DI MAJO, V., COPPOLA M. and COVELLI, V., 1994, Neoplastic tranformation of C3H10T1/2 cells: a study with fractionated doses of monoenergetic neutrons. Radiation Research, 138, 246–251.
  • STANBRIDGE, E. J., DER, C. J., DOERSEN, C. J., NISHIMI, R. Y PEEHL, D. M., WEINSTEIN, B. E. and WILKINSON, J. E.7 1982, Human cell hybrids analysis of transformation and tumorigenicity. Science, 215, 252–259.
  • SUN, C., REDPATH, J. L., COLMAN, M. and STANBRIDGE, E. J.7 1988, Further studies on the radiation-induced expression of a tumor-specific antigen in human cell hybrids. Radiation Research, 114, 84–93.
  • YANG, T. C., CRAISE, L. M., MEI, M. T. and TOBIAS, C. A., 1986, Dose protraction with low and high LET radiation on neoplastic transformation. Advances in Space Research, 6, 137–147.

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