References
- BECCIOLINI, A., BALZI, M., FABRICA, D. and POTTEN, C. S., 1996, Cell kinetics in rat small intestine after irradiation with sublethal dose at different times of the day. International Journal of Radiation Biology, 70, 281–288.
- BOARDER, T. A. and BLACKETT, N. M., 1976, The proliferative status of intestinal epithelial clonogenic cells: Sensitiv-ity to S phase specific cytotoxic agents. Cell and Tissue Kinetics, 9, 589–596.
- BURHOLT, D. R., HAGEMANN, R. F., COOPER, J. W., SCHENKEN, L. L. and LESHER, S., 1975, Damage and recovery assessment of the mouse jejunum to abdominal X-ray and adriamy-cin treatment. British Journal of Radiology, 48, 908–912.
- CAIRNIE, A. B., LAMERTON, L. F. and STEEL, G. G., 1965, Cell proliferation studies in the intestinal epithelium of the rat, I. determination of the kinetic parameters. Experimental Cell Research, 39, 528–538.
- CAIRNIE, A. B. and MILLEN, B. H., 1975, Fission of crypts in the small intestine of the irradiated mouse. Cell and Tissue Kinetics, 8, 189–196.
- CHOMICZEWSKI, K., HENDRY, J. H. and POTTEN, C. S., 1993, Accelerated repopulation of intestine post-irradiation following intraluminal injection of a mucosal cell suspension or its supernatant. Radiotherapy and Oncology, 26, 64–68.
- HAMILTON, E., 1977, Differences in survival of mouse colon crypts after whole- or partial-body irradiation. Interna-tionalJournal of Radiation Biology, 31, 341–347.
- HAMILTON, E., 1979, Induction of radioresistance in mouse colon crypts by X-rays. International Journal of Radiation Biology, 36, 537–545.
- HENDRY, J. H., 1994, Quantitation of intestinal clonogens by regeneration following cytotoxicity. Seminars in Developmental Biology, 4, 303–312.
- HENDRY, J. H., POTTEN, C. S. and ROBERTS, N. P., 1983, The gastrointestinal syndrome and mucosal clonogenic cells: relationships between target cell sensitivities, LD 50 and survival, and their modification by antibiotics. Radiation Research, 96, 100–112.
- but', K. and POTTEN, C. S., 1983, Response of intestinal cells of differing topological and hierarchical status to ten cytotoxic drugs and 5 sources of radiation. British Journal of Cancer, 47, 175–185.
- K. and POTTEN, C. S., 1987, Further studies on the response of intestinal crypts of different hierarchical status to cytotoxic drugs. British Journal of Cancer, 55, 113–123.
- LI, Y. Q., FAN, C. Y., O'CONNOR, P. J., WINTON, D. J. and POTTEN, C. S., 1992, Target cells for the cytotoxic effects of carcinogens in the murine small bowel. Carcinogenesis, 13, 361–368.
- LOEFFLER, M. and POTTEN, C. S., 1996, Stem cells and cellular predigrees— a conceptual introduction. In Stem Cells, edited by C. S. Potten (London: Academic) pp. 1–27.
- MERRITT, A. J., POTTEN, C. S., KEMP, C. J., HICKMAN, J. A., BALMAIN, A., LANE, D. P. and HALL, P. A., 1994, The role of p53 in spontaneous and radiation-induced apoptosis in the gastrointestinal tract of normal and p53-deficient mice. Cancer Research, 54, 614–617.
- MERRITT, A. J., POTTEN, C. S., WATSON, A. J., LOH, D. Y., NAKAYAMA, K. and HICKMAN, J. A., 1995, Differential expression of bc1-2 intestinal epithelia. Correlation with attenuation of apoptosis in colonic crypts and incidence of colonic neoplasia. Journal of Cell Science, 108, 2261–2271.
- POTTEN, C. S., 1977, Extreme sensitivity of some intestinal crypt cells to X and y irradiation. Nature, 269, 518–521.
- POTTEN, C. S., 1990, A comprehensive study of the radio-biological response of the murine (BDF1) small intestine. International Journal of Radiation Biology, 58, 925–973.
- POTTEN, C. S., 1995, Interleukin-11 protects the clonogenic stem cells in murine small-intestinal crypts from impairment of their reproductive capacity by radiation. International Journal of Cancer, 62, 356–361.
- POTTEN, C. S. and HENDRY, J. H., 1983, Stem cells in murine small intestine. In Stem Cells: Their Identification and Characterisation, edited by C. S. Potten (Edinburgh: Churchill Livingstone), pp. 155–199.
- POTTEN, C. S. and HENDRY, H. J., 1985, The micro-colony assay in mouse small intestine. In Cell Clones: Manual of Mammalian Cell Techniques, edited by C. S. Potten and J. H. Hendry (Edinburgh: Churchill Livingstone), pp. 50–60.
- POTTEN, C. S. and HENDRY, J. H., 1995, Clonogenic cells and the microcolony assay. In Radiation and Gut, edited by C. S. Potten and J. H. Hendry (Amsterdam: Elsevier), pp. 45–52.
- POTTEN, C. S., HENDRY, J. H., MOORE, J. V. and CHWALINSKI, S., 1983, Cytotoxic effects in gastro-intestinal epithelium (as exemplified by small intestine), In Cytotoxic Insult to Tissue: Effects on Cell Lineages, edited by C. S. Potten and J. H. Hendry (Edinburgh: Churchill Livingstone), pp. 105–152.
- POTTEN, C. S., LI, Y. Q., O'CONNOR, P. J. and WINTON, D. J., 1992, A possible explanation for the differential cancer incidence in the intestine, based on the distribution of the cytotoxic effects of carcinogens in the murine large bowel. Carcinogenesis, 13, 2305–2312.
- POTTEN, C. S. and LOEFFLER, M., 1990, Stem cells: attributes, cycles, spirals and uncertainties. Lessons for and from the crypt. Development, 110, 1001–1020.
- POTTEN, C. S., REZVANI, M., HENDRY, J. H., MOORE, J. V. and MAJOR, D., 1981, The correction of intestinal micro-colony counts for variation in size. International Journal of Radiation Biology, 40, 217–225.
- ROBERTS, S. A., 1990, DRFIT: a program for fitting radiation survival models. International Journal of Radiation Biology, 57, 1243–1246.
- ROBERTS, S. A., and POTTEN, C. S., 1994, Clonogen content of intestinal crypts: its deduction using a microcolony assay on whole mount preparations and its dependence on radiation dose. International Journal of Radiation Biology, 65, 477–481.
- THAMES, H. D. JR, WITHERS, H. R., MASON, K. A. and REID, B. 0., 1981, Dose—survival characteristics of mouse jejunal crypt cells. International Journal of Radiation Oncology, Biology, Physics, 7, 1591–1597.
- TUCKER, S. L., WITHERS, H. R., MASON, K. A. and THAMES, H. D. JR, 1983, A dose-surviving fraction curve for mouse colonic mucosa. European Journal of Cancer and Clinical Oncology, 19, 433–437.
- WATSON, A. J. M., MERRITT, A. J., JONES, L. S., ASKEW, J. N., ANDERSON, E., BRECCIOLINI, A., BALZI, M., POTTEN, C. S. and HICKMAN, J. A., 1996, Evidence for reciprocity of bc1-2 and p53 expression in human colorectal adeno-mas and carcinomas. British Journal of Cancer, 73, 889–895.
- WITHERS, H. R. and ELKIND, M. M., 1970, Microcolony survival assay for cells of mouse intestinal mucosa exposed to radiation. International Journal of Radiation Biology, 17, 261–268.
- WITHERS, H. R. and MASON, K. A., 1974, The kinetics of recovery in irradiated colonic mucosa of the mouse. Cancer, 34, 896–903.
- WRIGHT, N. and ALISON, M., 1984, The Biology of Epithelial Cell Populations, 2 vols (Oxford: Clarendon), II, 537–870.
- YAU, H. C. and CAIRNIE, A. B., 1979, Cell survival characteristics of intestinal stem cells and crypts of y-irradiated mice. Radiation Research, 80, 92–107.