583
Views
33
CrossRef citations to date
0
Altmetric
Papers

Quantification of genes encoding resistance to aminoglycosides, β-lactams and tetracyclines in wastewater environments by real-time PCR

, , , , &
Pages 219-230 | Received 05 Jun 2008, Published online: 19 Jun 2009

References

  • Amann , R I , Ludwig , W and Schleifer , K . 1995 . Phylogenetic identification and in situ detection of individual microbial cells without cultivation . Microbiol Rev , 59 ( 1 ) : 143 – 169 .
  • Aoshima , H , Kimura , A , Shibutani , A , Okada , C , Matsumiya , Y and Kubo , M . 2006 . Evaluation of soil bacterial biomass using environmental DNA extracted by slow-stirring method . Appl Microbiol Biotechnol , 71 ( 6 ) : 875 – 880 .
  • Auerbach , E A , Seyfried , E E and McMahon , K D . 2007 . Tetracycline resistance genes in activated sludge wastewater treatment plants . Water Res , 41 ( 5 ) : 1143 – 1151 .
  • Blattner , F R , Plunkett , G , Bloch , C A , Perna , N T , Burland , V , Riley , M , Collado-Vides , J , Glasner , J D , Rode , C K , Mayhew , G F , Gregor , J , Davis , N W , Kirkpatrick , H A , Goeden , M A , Rose , D J , Mau , B and Shao , Y . 1997 . The complete genome sequence of Escherichia coli K-12 . Science , 277 ( 5331 ) : 1453 – 1474 .
  • Chitnis , V , Chitnis , D , Patil , S and Kant , R . 2000 . Hospital effluent: A source of multiple drug-resistant bacteria . Curr Sci , 79 ( 7 ) : 989 – 991 .
  • Davies , J . 1994 . Inactivation of antibiotics and the dissemination of resistance genes . Science , 264 ( 5157 ) : 375 – 382 .
  • Fluit , A C , Visser , M R and Schmitz , F J . 2001 . Molecular detection of antimicrobial resistance . Clin Microbiol Rev , 14 ( 4 ) : 836 – 871 .
  • Esiobu , N , Armenta , L and Ike , J . 2002 . Antibiotic resistance in soil and water environments . Int J Environ Health Res , 12 : 133 – 144 .
  • Gill , S R , Fouts , D E , Archer , G L , Mongodin , E F , Deboy , R T , Ravel , J , Paulsen , I T , Kolonay , J F , Brinkac , L , Beanan , M , Dodson , R J , Daugherty , S C , Madupu , R , Angiuoli , S V , Durkin , A S , Haft , D H , Vamathevan , J , Khouri , H , Utterback , T , Lee , C , Dimitrov , G , Jiang , L , Qin , H , Weidman , J , Tran , K , Kang , K , Hance , I R , Nelson , K E and Fraser , C M . 2005 . Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain . J Bacteriol , 187 ( 7 ) : 2426 – 2438 .
  • Guillaume , G , Verbrugge , D , Chasseur-Libotte , M , Moens , W and Collard , J . 2000 . PCR typing of tetracycline resistance determinants (Tet A-E) in Salmonella enterica serotype Hadar and in the microbial community of activated sludges from hospital and urban wastewater treatment facilities in Belgium . FEMS Microbiol Ecol , 32 ( 1 ) : 77 – 85 .
  • Halling-Sorensen , B , Nors Nielsen , S , Lanzky , P F , Ingerslev , F , Holten Lutzhoft , H C and Jorgensen , S E . 1998 . Occurrence, fate and effects of pharmaceutical substances in the environment – a review . Chemosphere , 36 ( 2 ) : 357 – 393 .
  • Heuer , H , Krogerrecklenfort , E , Wellington , E MH , Egan , S , van Elsas , J D , van Overbeek , L , Collard , J M , Guillaume , G , Karagouni , A D , Nikolakopoulou , T L and Smalla , K . 2002 . Gentamicin resistance genes in environmental bacteria: Prevalence and transfer . FEMS Microbiol Ecol , 42 ( 2 ) : 289 – 302 .
  • Jarnheimer , P A , Ottoson , J , Lindberg , R , Stenström , T A , Johansson , M , Tysklind , M , Winner , M M and Olsen , B . 2004 . Fluoroquinolone antibiotics in a hospital sewage line; occurrence, distribution and impact on bacterial resistance . Scand J Infect Dis , 36 ( 10 ) : 752 – 755 .
  • Kummerer , K . 2004 . Resistance in the environment . J Antimicrob Chemother , 54 ( 2 ) : 311 – 320 .
  • Levy , S B . 1998 . The challenge of antibiotic resistance . Sci Am , 278 ( 3 ) : 46 – 53 .
  • Levy , S B and Marshall , B . 2004 . Antibacterial resistance worldwide: Causes, challenges and responses . Nat Med , 10 ( 12 ) : 122 – 129 .
  • Lindberg , R , Jarnheimer , P A , Olsen , B , Johansson , M and Tysklind , M . 2004 . Determination of antibiotic substances in hospital sewage water using solid phase extraction and liquid chromatography/mass spectrometry and group analogue internal standards . Chemosphere , 57 ( 10 ) : 1479 – 1488 .
  • Lowe , B , Avila , H A , Bloom , F R , Gleeson , M and Kusser , W . 2003 . Quantisation of gene expression in neural precursors by reverse-transcription polymerase chain reaction using self-quenched, fluorogenic primers . Anal Biochem , 315 ( 1 ) : 95 – 105 .
  • Lydmark , P , Brunström , R , Samuelsson , K , Mattson , A , Sörensson , F , Lindgren , P E and Hermansson , M . 2007 . Effects of environmental conditions on the nitrifying population dynamics in a pilot wastewater treatment plant . Environ Microbiol , 9 ( 9 ) : 2220 – 2233 .
  • Paulsen , I T , Banerjei , L , Myers , G S , Nelson , K E , Seshadri , R , Read , T D , Fouts , D E , Eisen , J A , Gill , S R , Heidelberg , J F , Tettelin , H , Dodson , R J , Umayam , L , Brinkac , L , Beanan , M , Daugherty , S , DeBoy , R T , Durkin , S , Kolonay , J , Madupu , R , Nelson , W , Vamathevan , J , Tran , B , Upton , J , Hansen , T , Shetty , J , Khouri , H , Utterback , T , Radune , D , Ketchum , K A , Dougherty , B A and Fraser , C M . 2003 . Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis . Science , 299 ( 5615 ) : 2071 – 2074 .
  • Pauwels , B and Verstraete , W . 2006 . The treatment of hospital wastewater: An appraisal . J Water Health , 4 ( 4 ) : 405 – 416 .
  • Patterson , A J , Colangeli , R , Spigaglia , P and Scott , K P . 2007 . Distribution of specific tetracycline and erythromycin resistance genes in environmental samples assessed by macroarry detection . Environ Microbiol , 9 ( 3 ) : 703 – 715 .
  • Peak , N , Knapp , C W , Yang , R K , Hanfelt , M M , Smith , M S , Aga , D S and Graham , D W . 2007 . Abundance of six tetracycline resistance genes in wastewater lagoons at cattle feedlots with different antibiotic use strategies . Environ Microbiol , 9 ( 1 ) : 143 – 151 .
  • Reinthaler , F F , Posch , J , Feierl , G , Wust , G , Haas , D , Ruckenbauer , G , Mascher , F and Marth , E . 2003 . Antibiotic resistance of E. coli in sewage and sludge . Water Res , 37 ( 8 ) : 1685 – 1690 .
  • Rhodes , G , Huys , G , Swings , J , McGann , P , Hiney , M , Smith , P and Pickup , R W . 2000 . Distribution of oxytetracycline resistance plasmids between aeromonads in hospital and aquaculture environments: Implication of Tn1721 in dissemination of the tetracycline resistance determinant tetA . Appl Environ Microbiol , 66 ( 9 ) : 3883 – 3890 .
  • Rice , E W , Messer , J W , Johnson , C H and Reasoner , D J . 1995 . Occurrence of high-level aminoglycoside resistance in environmental isolates of enterococci . Appl Environ Microbiol , 61 ( 1 ) : 374 – 376 .
  • Roberts , M C . 1996 . Tetracycline resistance determinants: Mechanisms of action, regulation of expression, genetic mobility, and distribution . FEMS Microbiol Rev , 19 ( 1 ) : 1 – 24 .
  • Schwartz , T , Kohnen , W , Jansen , B and Obst , U . 2003 . Detection of antibiotic-resistant bacteria and their resistance genes in wastewater, surface water, and drinking water biofilms . FEMS Microbiol Ecol , 43 ( 3 ) : 325 – 335 .
  • Strindhall , J , Lindgren , P E , Lofgren , S and Kihlstrom , E . 2002 . Variations among clinical isolates of Staphylococcus aureus to induce expression of E-selectin and ICAM-1 in human endothelial cells . FEMS Immunol. Med Microbiol , 32 ( 3 ) : 227 – 235 .
  • Sundberg , C , Stendahl , J SK , Tonderski , K and Lindgren , P E . 2007 . Overland flow systems for treatment of landfill leachates – potential nitrification and structure of the ammonia-oxidising bacterial community during a growing season . Soil Biol Biochem , 39 : 127 – 138 .
  • Sundsfjord , A , Simonsen , G S , Haldorsen , B C , Haaheim , H , Hjelmevoll , S O , Littauer , P and Dahl , K H . 2004 . Genetic methods for detection of antimicrobial resistance . APMIS , 112 ( 11–12 ) : 815 – 837 .
  • Volkmann , H , Schwartz , T , Bischoff , P , Kirchen , S and Obst , U . 2004 . Detection of clinically relevant antibiotic-resistance genes in municipal wastewater using real-time PCR (TaqMan) . J Microbiol Meth , 56 ( 2 ) : 277 – 286 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.