146
Views
25
CrossRef citations to date
0
Altmetric
Paper

Whole blood and mononuclear cell glutathione response to dietary whey protein supplementation in sedentary and trained male human subjects

, &
Pages 131-141 | Published online: 06 Jul 2009

References

  • Antonio J, Sanders MS & Van Gammeren D (2001): The effects of bovine colostrums supplementation on body composition and exercise performance in active men and women. Nutrition 17, 243–247.
  • Bauman PF, Smith TK & Bray TM (1988): The effect of dietary protein and sulfur amino acids on hepatic glutathione concentration and glutathione dependent enzyme activities in the rat. Can. J. Phys. Pharm. 66, 1048–1052.
  • Bell G, Syrotuik D, Martin T, Burnham R & Quinney HA (2000): The effect of concurrent strength training and endurance training on skeletal muscle properties and hormone levels. Eur. J. Appl. Physiol. 81(5),418–427.
  • Bounous G & Gold P (1991): The biological activity of undenatured dietary whey proteins: role of glutathione. Clin. Invest. Med. 14, 296–309.
  • Bounous G & Kongshavn PAL (1989): Influence of protein type in nutritionally adequate diets on the development of immunity. In Absorption and Utilization of Amino Acids, ed. M Friedman. Boca Raton, FL: CRC Press.
  • Cho ES, Johnson N & Snider BCF (1984): Tissue glu- tathione as a cysteine reservoir during cystine depletion in growing rats. J. Nutr. 114, 1853–1862.
  • Colker CM, Swain MA, Fabucini B, Shi QH & Kalman DS (2000): Effects of supplemental protein on body composi-tion and muscular strength in healthy athletic male adults. Curr. Ther. Res. Clin. Exp. 61, 19–28.
  • Dethmers JK & Meister A (1981): Glutathione export by human lymphoid cells— depletion of glutathione by inhibition of its synthesis decreases export and increases sensitivity to irradiation. Proc. Natl. Acad. Sci. USA 78, 7492–7496.
  • Droge W, Schulze-Osthoff K, Mihm S, Galter D, Schenk H, Eck HP, Roth S & Gmunder H (1994): Functions of glutathione and glutathione disulfide in immunology and immunopathology. FASEB J. 8, 1131–1138.
  • Droge W (1996): Modulation of the immune response by cysteine and cysteine derivatives. Riv. Ital. Nutr. Parenter-ale Enterale 14, 1–4.
  • Gohil K, Viguie C, Stanley WC, Brooks GA & Packer L (1988): Blood glutathione oxidation during human ex-ercise. J. Appl. Phys. 64, 115–119.
  • Griffith OW (1980): Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal. Biochem. 106, 207–212.
  • Hoog JO, Homgren A, D’Silva C, Douglas KT & Seddon AP (1982): Glutathione derivatives as inhibitors of glutaredoxin and ribonucleotide reductase from Escher-ichia-coli. FEBS Lett. 138, 59–61.
  • Hum S, Koski KG & Hoffer LJ (1992): Varied protein intake alters glutathione metabolism in rats. J. Nutr. 122, 2010–2018.
  • Immunotech Research Corporation Limited (1997): Anti-cancer therapeutic composition containing whey protein concentrate. International Patent number PCT/CA 93/ 00309.
  • Kaplowitz N, Aw TY & Ookhtens M (1985): The regulation of hepatic glutathione. Ann. Rev. Pharm. Toxicol. 25, 715–744.
  • Kinscherf R, Fischbach T, Mihm S, Roth S, Hohenhaus- Sievert E, Wiess C, Edler L, Bartsch P & Droge W (1994): Effect of glutathione depletion and oral N-acetyl-cysteine treatment on CD4+ and CD8+ cells. FASEB J. 8, 448–451.
  • Kretzschmar M & Muller D (1993): Aging, training and exercise: a review of effects on plasma glutathione and lipid peroxides. Sports Med. 15, 196–209.
  • Lands LC, Grey VL & Smountas AA (1999): Effect of supplementation with a cysteine donor on muscular performance. J. Appl. Physiol. 87, 1381–1385.
  • Lauterburg BH, Adams JD & Mitchell JR (1984): Hepatic glutathione homeostasis in the rat: efflux accounts for glutathione turnover. Hepatology 4, 586–590.
  • Lemon PWR (1998): Effects of exercise on dietary protein requirements. Int. J. Sport Nutr. 8, 426–447.
  • Lew H, Pyke S & Quintanilha A (1995): Changes in the glutathione status of plasma, liver, and muscle following exhaustive exercies in rats. FEBS Lett. 185, 262–266.
  • Meister A & Anderson ME (1983): Glutathione. Ann. Rev. Biochem. 52, 711–760.
  • Micke P, Beeh KM & Buhl R (2002): Effects of long-term supplementation with whey proteins on plasma glutathione levels of HIV-infected patients. Eur. J. Nutr. 41, 12–18. Middleton NE (2001): Chapter 3: an evaluation of matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) in the qualitative characterization of concentrated whey protein products. Masters Thesis, Department of Agriculture, Food, Nutri-tional Science, University of Alberta.
  • Pelegri C, Rodriguez-Palmero M, Paz Morante M, Comas J, Castell M & Franch A (1995): Comparison of four lymphocyte isolation methods applied to rodent T cell subpopulations and B cells. J. Immunol. Methods 187, 265–271.
  • Pendergast J & Little R (1988): Repeated measures analysis with the SAS system. 13th SUGI Proceedings, Cary, NC: SAS Institute. pp. 1205–1211.
  • Sen CK, Marin E, Kretzshmar M & Hannienen O (1992):_;
  • Skeletal muscle and liver glutathione homeostasis in response to training, exercise, and immobilization. J. Appl. Physiol. 73, 1265-1272.
  • Sen CK (1997): Nutritional biochemistry of cellular glu- tathione. Nutr. Biochem. 8, 660–672.
  • Sen CK (1999): Glutathione homeostasis in response to exercise training and nutritional supplements. Mol. Cell. Biochem. 196, 31–42.
  • Steel RGD, Torrie JH & Dickey DA (1997): Analysis of variance III: factorial experiments. In Principles and Procedures of Statistics: a Biometrical Approach, pp. 352–399. Boston, MA: McGraw Hill.
  • Tietze F (1969): Enzymatic method for quantitative deter- mination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 27, 502–522.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.