Chemical Composition of Myrtus communis L. and Proapoptotic Effects on the A549 Cell Line

References

• Kwan, Y.P., Saito, T., Ibrahim, D., Al-Hassan, F.M., Ein Oon, C., Chen, Y., Jothy, S.L., Kanwar, J.R. and Sasidharan, S. (2016). Evaluation of the cytotoxicity, cell-cycle arrest, and apoptotic induction by Euphorbia hirta in MCF-7 breast cancer cells. Pharm. Biol. 54(7): 1223–1236.
   PubMed Web of Science ®Google Scholar
• Marsik, P., Kokoska, L., Landa, P., Nepovim, A., Soudek, P. and Vanek, T. (2005). In-vitro inhibitory effects of thymol and quinones of Nigella sativa seeds on cyclooxygenase-1- and -2-catalyzed prostaglandin E2 biosynthese. Planta Med. 71(8): 739-742.
   PubMed Web of Science ®Google Scholar
• De Andrade, T.U., Brasil, G.A., Endringer, D.C., Da Nobrega, F.R. and De Sousa, D.P. (2017). Cardiovascular activity of the chemical constituents of essential oils. Molecules. 22(9): 1539.
   Web of Science ®Google Scholar
• Nirmala, M.J., Durai, L., Gopakumar, V. and Nagarajan, R. (2019). Anticancer and antibacterial effects of a clove bud essential oil-based nanoscale emulsion system. Int. J. Nanomedicine. 14: 6439-6450.
   PubMed Web of Science ®Google Scholar
• [[https://www.cancer.org/content/dam/CRC/PDF/Public/6041.00.pdf], last access date: 01.07. 2020.
   Google Scholar
• Tan, G., Gy llenhaal, C. and Soejarto, D.D. (2006). Biodiversity as a source of anticancer drugs. Curr. Drug Targets. 7(3): 265-277.
   PubMed Web of Science ®Google Scholar
• Mir, M.A., Bashir, N., Alfaify, A. and Oteef, M.D.Y. (2020). GC-MS analysis of Myrtus communis extract and its antibacterial activity against Gram-positive bacteria. BMC Complement. Med. Ther. 20(1): 86.
   PubMedGoogle Scholar
• Sateriale, D., Facchiano, S., Colicchio, R., Pagliuca, C., Varricchio, E., Paolucci, M., Volpe, M.G., Salvatore, P. and Pagliarulo, C. (2020). In vitro synergy of polyphenolic extracts from honey, myrtle and pomegranate against oral pathogens, S. mutans and R. Dentocariosa. Front. Microbiol. 11: 1465.
   PubMed Web of Science ®Google Scholar
• Man, A., Santacroce, L., Jacob, R., Mare, A. and Man, L. (2019). Antimicrobial activity of six essential oils against a group of human pathogens: A comparative study. Pathogens. 8(1): 15.
   PubMed Web of Science ®Google Scholar
• Aleksic, V. and Knezevic, P. (2014). Antimicrobial and antioxidative activity of extracts and essential oils of Myrtus communis L. Microbiol. Res. 169(4): 240-254.
   PubMed Web of Science ®Google Scholar
• Aidi Wannes, W., Mhamdi, B., Sriti, J., Ben, Jemia, M., Ouchikh, O., Hamdaoui, G., Kchouk, M.E. and Marzouk, B. (2010). Antioxidant activities of the essential oils and methanol extracts from myrtle (Myrtus communis var. italica L.) leaf, stem and flower. Food Chem. Toxicol. 48(5): 1362-1370.
   PubMed Web of Science ®Google Scholar
• Cruciani, S., Santaniello, S., Fadda, A., Sale, L., Sarais, G., Sanna, D., Mulas, M., Ginesu, G.C., Cossu, M.L., Serra, P.A., Ventura, C. and Maioli, M. (2019). Extracts from Myrtle Liqueur Processing Waste Modulate Stem Cells Pluripotency under Stressing Conditions. Biomed. Res. Int. 5641034.
   Google Scholar
• Hayder, N., Kilani, S., Abdelwahed, A., Mahmoud, A., Meftahi, K., Ben Chibani, J., Ghedira, K. and Chekir-Ghedira, L. (2003). Antimutagenic activity of aqueous extracts and essential oil isolated from Myrtus communis. Pharmazie. 58(7): 523-524.
   PubMed Web of Science ®Google Scholar
• Mahmoudvand, H., Ezzatkhah, F., Sharififar, F., Sharifi, I., and Dezaki, E.S. (2015). Antileishmanial and cytotoxic effects of essential oil and methanolic extract of Myrtus communis L. Korean J. Parasitol. 53(1): 21-27.
   PubMed Web of Science ®Google Scholar
• Barac, A., Donadu, M., Usai, D., Spiric, V.T., Mazzarello, V., Zanetti, S., Aleksic, E., Stevanovic, G., Nikolic, N. and Rubino, S. (2018). Antifungal activity of Myrtus communis against Malassezia sp. isolated from the skin of patients with pityriasis versicolor. Infection. 46(2): 253-257.
   PubMed Web of Science ®Google Scholar
• Al-Hadeethi, M.A., Al-Anbari, A.K. and Al-Dulimi, S.A. (2015). Identify the essential oils in Myrtus communis L. leaves. IJACEBS. 2(2): 116-118.
   Google Scholar
• Harassi, Y., Tilaoui, M., Idir, A., Frederic, J., Baudino, S., Ajouaoi, S., Mouse, H.A. and Zyad, A. (2019). Phytochemical analysis, cytotoxic and antioxidant activities of Myrtus communis essential oil from Morocco. J. Complement. Integr. Med. 16(3): /j/jcim.2019.16.issue-3/jcim-2018-0100/jcim-2018-0100.xml.
   Google Scholar
• Usai, M., Marchetti, M., Culeddu, N. and Mulas, M. (2018). Chemical composition of Myrtle (Myrtus communis L.) berries essential oils as observed in a collection of genotypes. Molecules. 23(10): 2502-2522.
   Web of Science ®Google Scholar
• Fadil, M., Fikri-Benbrahim, K., Rachiq, S., Ihssane, B., Lebrazi, S., Chraibi, M., Haloui, T. and Farah, A. (2018). Combined treatment of Thymus vulgaris L., Rosmarinus officinalis L. and Myrtus communis L. essential oils against Salmonella typhimurium: Optimization of antibacterial activity by mixture design methodology. Eur. J. Pharm. Biopharm. 126: 211-220.
   PubMed Web of Science ®Google Scholar
• Parveen, A., Akash, M.S., Rehman, K. and Kyunn, W.W. (2016). Dual role of p21 in the progression of cancer and its treatment. Crit. Rev. Eukaryot. Gene Expr. 26(1): 49-62.
   PubMed Web of Science ®Google Scholar
• Nikolaou, M., Pavlopoulou, A., Georgakilas, A.G. and Kyrodimos, E. (2018). The challenge of drug resistance in cancer treatment: a current overview. Clin. Exp. Metastasis. 35(4): 309-318.
   PubMed Web of Science ®Google Scholar
• Duran, N., Duran, G.G., Ay, E., Kaya, D.A., Kaya, M.G.S. and Mert, A. (2016). In-vitro cytotoxic activity of Nigella sativa L. on human malignant melanoma cell lines. The 6th International Conference on Advanced Materials and Systems (ICAMS). 1-6. DOI: 10.24264/icams-2016.II.10
   Google Scholar
• Duran, G.G., Duran, N., Ay, E., Kaya, M.G.A. and Kaya, D.A. (2016). Synergistic activities of the essential oils Hypericum perforatum with methotrexate on human breast cancer cell line MCF-7. The 6th International Conference on Advanced Materials and Systems (ICAMS). 40-46. DOI: 10.24264/icams-2016.II.9
   Google Scholar
• Yu-ichiro, N. and Erina, K. (2017). Caspase-dependent non-apoptotic processes in development. Cell Death Differ. 24(8): 1422-1430.
   PubMed Web of Science ®Google Scholar
• Yuhei, K., Yu-ichiro, N. and Erina, K. (2016). Apoptosis in cellular society: Communication between apoptotic cells and their neighbors. Int. J. Mol. Sci. 17(12): 2144-2148.
   Web of Science ®Google Scholar
• Veiga, G.L.D., Silva, R.D.M.D., Pereira, E.C., Azzalis, L.A., Alves, B.D.C.A. and Gehrke, F.S. (2019). The role of survivin as a biomarker and potential prognostic factor for breast cancer. Rev. Assoc. Med. Bras. 65(6): 893-901.
   PubMed Web of Science ®Google Scholar
• https://www.who.int/ionizing_radiation/research/iarc/en/ (accessible date; 5th day of May, 2020).
   Google Scholar
• Cho, J. H. (2017). Immunotherapy for non-small-cell lung cancer: Current Status and Future Obstacles. Immune Netw. 17(6): 378-391.
   PubMed Web of Science ®Google Scholar
• Amaral, R.G., dos Santos, S.A., Andrade, L.N., Severino, P. and Carvalho, A.A. (2019). Natural Products as Treatment against Cancer: A Historical and Current Vision Clinics in Oncology. 4: 1562-1568.
   Google Scholar
• Bahadirli, N.P. and Ayanoglu, F. (2019). Preliminary results: Assessment of new Salvia chemotypes for herbal tea industry by hybridization. Scientific Papers. Series A. Agronomy, Vol. LXII, No. 1.
   Google Scholar
• Adams, R.P. (2001). Identification of essential oil components by gas chromatography/quadrupole mass spectrometry, Allured Publishing Corp.: Carol Stream, USA.
   Google Scholar
• Vandendool, H. and Kratz, Pd. A. (1963). Generalization of the retention index system including linear temperature programmed gas-liquid partition chromatography. J Chromatogr. 11: 463-471.
   PubMed Web of Science ®Google Scholar
• Babushok, V.I., Linstrom, P.J., Zenkevich, I.G. (2011). Retention indices for frequently reported compounds of plant essential oils. J. Phys. Chem. Ref. Data. 40(4):1-47.
   Web of Science ®Google Scholar
• Arora, R, Singh, B., Vig, A.P. and Arora, S. (2016). Conventional and modified hydrodistillation method for the extraction of glucosinolate hydrolytic products: A comparative account. Springer Plus. 5: 479-482.
   PubMedGoogle Scholar
• Mitupatum, T., Aree, K., Kittisenachai, S., Roytrakul, S., Puthong, S., Kangsadalampai, S. and Rojpibulstit, P. (2015). Hep88 mAb-mediated paraptosis-like apoptosis in HepG2 cells via downstream upregulation and activation of caspase-3, caspase-8 and caspase-9. Asian Pac. J. Cancer Prev. 16(5): 1771-1779.
   PubMedGoogle Scholar
• Kalia, S. and Bansal, M.P. (2009). Regulation of apoptosis by caspases under oxidative stress conditions in mice testicular cells: in vitro molecular mechanism. Mol. Cell. Biochem. 322(1-2): 43-52.
   PubMed Web of Science ®Google Scholar
• Taamalli, A., Iswaldi. I., Arraez-Roman, D., Segura-Carretero, A., Fernandez-Gutierrez, A. and Zarrouk, M. (2014). UPLC-QTOF/MS for a rapid characterisation of phenolic compounds from leaves of Myrtus communis L. Phytochem. Anal. 25(1): 89-96.
   PubMed Web of Science ®Google Scholar
• Izgi, K., Iskender, B., Jauch, J., Sezen, S., Cakir, M., Charpentier, M., Canatan, H. and Sakalar, C. (2015). Myrtucommulone-A induces both extrinsic and intrinsic apoptotic pathways in cancer cells. J. Biochem. Mol. Toxicol. 29(9): 432-439.
   PubMed Web of Science ®Google Scholar
• Hrubik, J., Kai, S.N., Gli, B., Jovin, E., Mimica-Duki, N.M. and Kovacevic, R.M. (2012). Myrtus comunis and Eucalyptus camaldulensis cytotoxicity on breast cancer cells. Proc. Nat. Sci, Matica Srpska Noviç Sad. 123(65): 65-73.
   Google Scholar
• Tretiakova, I., Blaesius, D., Maxia, L., Wesselborg, S., Schulze-Osthoff, K, Cinatl, J., Michaelis, M. and Werz, O. (2008). Myrtucommulone from Myrtus communis induces apoptosis in cancer cells via the mitochondrial pathway involving caspase-9. Apoptosis. 13(1): 119-131.
   PubMed Web of Science ®Google Scholar
• Gartel, A.L. and Tyner, A.L. (2002). The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol. Cancer. Ther. 1(8): 639-649.
   PubMed Web of Science ®Google Scholar
• Kang, H.J. and Rosenwaks, Z. (2018). p53 and reproduction. Fertil Steril. 109(1): 39-43.
   PubMed Web of Science ®Google Scholar
• Lakin, N.D. and Jackson, S.P. (1999). Regulation of p53 in response to DNA damage. Oncogene. 18(53): 7644-7655.
   PubMed Web of Science ®Google Scholar
• Oztekin, M., Koyuncu, H., Petek, M., Ulasli, M. and Unan, S. (1998). The effect of Myrtus communis L. oil on ehrlich tumour. 2nd Congress of the Balkan Union of Oncology, September 10-14, Turkey, 383-386.
   Google Scholar