Exogenous PML/RARα Fusion Gene Responds to All-trans Retinoic Acid Results in Differentiation of the Human B Cell Line

References

• Groopman, J. and Ellman, J. (1979). Acute promyelocytic leukemia, American Journal of Hematology, 7, 395–408.
   PubMed Web of Science ®Google Scholar
• Larson, R. A., Kondo, K., Vardiman, J. W., Butler, A. E., Golomb, H. M. and Rowly, J. D. (1984). Evidence of a 15;17 translocation in every patient with acute promyelocytic leukemia, American Journal of Medicine, 76, 827–841.
   PubMed Web of Science ®Google Scholar
• Alcalay, M., Zangrilli, D., Pandolfi, P. P., Longo, L., Mencarelli, A., Giacomucci, A., Rocchi, M., Biondi, A., Rambaldi, A., Lo Coco, F., Diverio, D., Donti, E., Grignani, F. and Pellicci, P. G. (1991). Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor α locus, Proceedings of the National Academy of Science of United States of America, 88, 1977–1981.
   PubMed Web of Science ®Google Scholar
• Kakizuka, A., Jr. Miller, W. H., Umesono, K., Jr. Warrell, R. P., Frankel, S. R., Murty, V. V. V. S., Dmitrovsky, E. and Evans, R. M. (1991). Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML, Cell, 66, 663–674.
   PubMed Web of Science ®Google Scholar
• Goddard, A. D., Borrow, J., Freemont, P. S. and Solomon, E. (1991). Characterization of a zinc finger gene disrupted by the t(15;17) in acute promyelocytic leukemia, Science, 254, 1371–1374.
   PubMed Web of Science ®Google Scholar
• Huang, M. E., Yu-Chen, Y., Shu-Rong, C., Jin-Ren, C., Jla-Xiang, L., Long-Jun, G. and Zhen-Yi, W. (1988). Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia, Blood, 72, 567–572.
   PubMed Web of Science ®Google Scholar
• Warrell, R. P., Frankel, S. P., Miller, W. H., Scheinberg, D. A., Itri, L. M., Hittelman, W. N., Vyas, R., Andreef, M., Tafuri, A., Jakubowski, A., Gabrilove, J., Gordon, M. S. and Dmitrovsky, E. (1991). Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans retinoic acid), New England Journal Medicine, 324, 1385–1393.
   PubMed Web of Science ®Google Scholar
• Fenaux, P., Deley, M. C., Castaigne, S., Archimbaud, E., Chomienne, C., Link, H., Guerci, A., Duarte, M., Daniel, M. T., Bowen, D., Huebner, G., Bauters, F., Fegueux, N., Fey, M., Sanz, M., Lowenberg, B., Maloisel, F., Auzanneau, G., Sadoun, A., Gardin, C., Bastion, Y., Gasner, A., Jacky, E., Dombret, H., Chastang, C., Degos, L. and the European APL 91 group (1993). Effect of all trans retinoic acid in newly diagnosed acute promyelocytic leukemia. Result of a multicenter randomized trial, Blood, 82, 3241–3249.
   PubMed Web of Science ®Google Scholar
• Solomon, E., Borrow, J. and Goddard, A. D. (1991). Chromosome aberrations and cancer, Science, 254, 1153–1160.
   PubMed Web of Science ®Google Scholar
• Maeda, Y., Horiuchi, F., Miyatake, J., Sono, H., Tatsumi, Y., Urase, F., Irimajiri, K. and Horiuchi, A. (1996). Inhibition of growth and induction of apoptosis by all-trans retinoic acid in lymphoid cell lines transfected with the PML/RARα fusion gene, British Journal of Haematology, 93, 973–976.
   PubMed Web of Science ®Google Scholar
• Altabef, M., Garcia, M., Lavau, C., Bae, S.-C., Dejean, A. and Samarut, J. (1996). A retrovirus carrying the promyelocyte-retinoic acid receptor PML-RARα fusion gene transforms haematopoietic progenitors in vitro and induces acute leukaemias, The EMBO Journal, 15, 2707–2716.
   PubMed Web of Science ®Google Scholar
• Brown, D., Kogan, S., Lagasse, E., Weissman, I., Alcalay, M., Pelicci, P. G., Atwater, S. and Bishop, J. M. (1997). A PML-RARα transgene initiates murine acute promyelocytic leukemia, Proceedings of the National Academy of Science of United States of America, 94, 2551–2556.
   PubMed Web of Science ®Google Scholar
• Grignani, F., Fagioli, M., Alcalay, M., Longo, L., Pandolfi, P. P., Donti, E., Biondi, A., Lo Coco, F., Grignani, F. and Pelicci, P. G. (1994). Acute promyelocytic leukemia: from genetics to treatment, Blood, 83, 10–25.
   PubMed Web of Science ®Google Scholar
• de The, H., Chomienne, C., Lanotte, M., Degos, L. and Dejean, A. (1990). The t(15;17) translocation of acute promyelocytic leukemia fused the retinoic acid receptor-α gene to a novel transcribed locus, Nature, 347, 558–561.
   PubMed Web of Science ®Google Scholar
• de The, H., Lavau, C., Marchio, A., Chomienne, C., Degos, L. and Dejean, A. (1991). The PML/RARα fusion mRNA genarated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR, Cell, 66, 675–684.
   PubMed Web of Science ®Google Scholar
• Dyck, J. A., Maul, G. G., Jr. Miller, W. H., Chen, J. D., Kakizuka, A. and Evans, R. M. (1994). A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein, Cell, 76, 333–343.
   PubMed Web of Science ®Google Scholar
• Grignani, F., Ferrucci, P. F., Testa, U., Talamo, G., Fagioli, M., Alcalay, M., Mencarelli, A., Grignani, F., Peschle, C., Nicoletti, I. and Pelicci, P. G. (1993). The acute promyelocytic leukemia-specific PML/RARα fusion protein inhibits differentiation and promotes survival of myeloid precursor cells, Cell, 74, 423–431.
   PubMed Web of Science ®Google Scholar
• Levy, Y., Labaume, S., Gendron, M.-C. and Brouet, J.-C. (1994). Modulation of spontaneous B-cell differentiation in macroglobulinemia by retinoic acid, Blood, 83, 2206–2210.
   PubMed Web of Science ®Google Scholar
• Israel, H., Odziemiec, C. and Ballow, M. (1991). The effects of retinoic acid on immunoglobulin synthesis by human cord blood mononuclear cells, Clinical Immunology and Immunopathology, 59, 417–425.
   PubMedGoogle Scholar