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Stress
The International Journal on the Biology of Stress
Volume 24, 2021 - Issue 2: Commemorating the 2nd Munich Stress Conference
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Original Research Reports

Social defeat stress affects resident’s clock gene and bdnf expression in the brain

, , , , , & ORCID Icon show all
Pages 206-212 | Received 07 Dec 2019, Accepted 18 Apr 2020, Published online: 16 Jun 2020

References

  • Albrecht, U. (2012). Timing to perfection: The biology of central and peripheral circadian clocks. Neuron, 74(2), 246–260. https://doi.org/10.1016/j.neuron.2012.04.006
  • Asai, M., Yoshinobu, Y., Kaneko, S., Mori, A., Nikaido, T., Moriya, T., Akiyama, M., & Shibata, S. (2001). Circadian expression of Per gene m RNA expression in the suprachiasmatic nucleus, paraventricular nucleus, and pineal body of aged rats. Journal of Neuroscience Research, 66(6), 1133–1139. https://doi.org/10.1002/jnr.10010
  • Bendová, Z., Sládek, M., & Svobodová, I. (2012). The expression of NR2B subunit of NMDA receptor in the suprachiasmatic nucleus of Wistar rats and its role in glutamate-induced CREB and ERK1/2 phosphorylation. Neurochemistry International, 61(1), 43–47. https://doi.org/10.1016/j.neuint.2012.04.016
  • Bendová, Z., Sumová, A., & Mikkelsen, J. D. (2009). Circadian and developmental regulation of N- methyl- d- aspartate- receptor 1 m RNA splice variants and N- methyl- d- aspartate- receptor 3 subunit expression within the rat suprachiasmatic nucleus. Neuroscience, 159(2), 599–609. https://doi.org/10.1016/j.neuroscience.2009.01.016
  • Ben-Hamo, M., Larson, T. A., Duge, L. S., Sikkema, C., Wilkinson, C. W., de la Iglesia, H. O., & González, M. M. (2017). Circadian forced desynchrony of the master clock leads to phenotypic manifestation of depression in rats. e Neuro, 3(6), 1–13.
  • Berton, O., Mc Clung, C. A., Dileone, R. J., Krishnan, V., Renthal, W., Russo, S. J., Graham, D., Tsankova, N. M., Bolanos, C. A., Rios, M., Monteggia, L. M., Self, D. W., & Nestler, E. J. (2006). Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress. Science, 311(5762), 864–868. https://doi.org/10.1126/science.1120972
  • Bland, S. T., Tamlyn, J. P., Barrientos, R. M., Greenwood, B. N., Watkins, L. R., Campeau, S., Day, H. E., & Maier, S. F. (2007). Expression of fibroblast growth factor-2 and brain-derived neurotrophic factor m RNA in the medial prefrontal cortex and hippocampus after uncontrollable or controllable stress. Neuroscience, 144(4), 1219–1228. https://doi.org/10.1016/j.neuroscience.2006.11.026
  • Bohus, B., Koolhaas, J. M., de Ruiter, A. J. H., & Heijnen, C. J. (1992). Psycho-social stress: Differential alteration in immune system function and tumor growth. In R. Kvietnansky, R. Mc Carty, & J. Axelrod (Eds.), Atress: Neuroedocrine and Molecular Approaches (pp. 607–621). S.A. Publishers.
  • Bova, R., Micheli, M. R., Qualadrucci, P., & Zucconi, G. G. (1998). BDNF and trk B m RNAs oscillate in rat brain during the light-dark cycle. Molecular Brain Research, 57(2), 321–324. https://doi.org/10.1016/S0169-328X(98)00092-8
  • Cheon, S., Park, N., Cho, S., & Kim, K. (2013). Glucocorticoid-mediated Period2 induction delays the phase of circadian rhythm. Nucleic Acids Research, 41(12), 6161–6174. https://doi.org/10.1093/nar/gkt307
  • Chi-Castañeda, D., & Ortega, A. (2018). Circadian regulation of glutamate transporters. Frontiers in Endocrinology, 9, 340. https://doi.org/10.3389/fendo.2018.00340
  • Christiansen, S. L., Bouzinova, E. V., Fahrenkrug, J., & Wiborg, O. (2016). Altered expression pattern of clock genes in a rat model of depression. International Journal of Neuropsychopharmacology, 19(11), pyw061. https://doi.org/10.1093/ijnp/pyw061
  • Chun, L. E., Christensen, J., Woodruff, E. R., Morton, S. J., Hinds, L. R., & Spencer, R. L. (2018). Adrenal-dependent and -independent stress-induced Per1 m RNA in hypothalamic paraventricular nucleus and prefrontal cortex of male and female rats. Stress, 21(1), 69–83. https://doi.org/10.1080/10253890.2017.1404571
  • Chung, S., Lee, E. J., Yun, S., Choe, H. K., Park, S. B., Son, H. J., Kim, K. S., Dluzen, D. E., Lee, I., Hwang, O., Son, G. H., & Kim, K. (2014). Impact of circadian nuclear receptor REV-ERBα on midbrain dopamine production and mood regulation. Cell, 157(4), 858–868. https://doi.org/10.1016/j.cell.2014.03.039
  • Colyn, L., Venzala, E., Marco, S., Perez-Otaño, I., & Tordera, R. M. (2019). Chronic social defeat stress induces sustained synaptic structural changes in the prefrontal cortex and amygdala. Behavioural Brain Research, 373, 112079. https://doi.org/10.1016/j.bbr.2019.112079
  • Cooper, O., Bonert, V., Moser, F., Mirocha, J., & Melmed, S. (2017). Altered pituitary gland structure and function in posttraumatic stress disorder. Journal of the Endocrine Society, 1(6), 577–587. https://doi.org/10.1210/js.2017-00069
  • Curtis, A. M., & Fagundes, C. T. (2016). Understanding the role of cellular molecular clocks in controlling the innate immune response. Methods in Molecular Biology, 1390, 301–316. https://doi.org/10.1007/978-1-4939-3335-8_19
  • Dmitrzak-Weglarz, M., & Reszka, E. (2017). Pathophysiology of depression: Molecular regulation of melatonin homeostasis - Current status. Neuropsychobiology, 76(3), 117–129. https://doi.org/10.1159/000489470
  • Dong, L., Bilbao, A., Laucht, M., Henriksson, R., Yakovleva, T., Ridinger, M., Desrivieres, S., Clarke, T. K., Lourdusamy, A., Smolka, M. N., Cichon, S., Blomeyer, D., Treutlein, J., Perreau-Lenz, S., Witt, S., Leonardi-Essmann, F., Wodarz, N., Zill, P., Soyka, M., … Schumann, G. (2011). Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking. The American Journal of Psychiatry, 168(10), 1090–1098. https://doi.org/10.1176/appi.ajp.2011.10111579
  • Ergang, P., Mikulecka, A., Vodicka, M., Vagnerova, K., Miksik, I., & Pacha, J. (2018). Social defeat stimulates local glucocorticoid regeneration in lymphoid organs. Endocrine Connections, 7(12), 1389–1396.
  • Fanous, S., Hammer, R. P., Jr., & Nikulina, E. M. (2010). Short- and long-term effects of intermittent social defeat stress on brain-derived neurotrophic factor expression in mesocorticolimbic brain regions. Neuroscience, 167(3), 598–607. https://doi.org/10.1016/j.neuroscience.2010.02.064
  • Kolker, D. E., Vitaterna, M. H., Fruechte, E. M., Takahashi, J. S., & Turek, F. W. (2004). Effects of age on circadian rhythms are similar in wild-type and heterozygous clock mutant mice. Neurobiology of Aging, 25(4), 517–523. https://doi.org/10.1016/j.neurobiolaging.2003.06.007
  • Koo, J. W., Chaudhury, D., Han, M. H., & Nestler, E. J. (2019). Role of mesolimbic brain-derived neurotrophic factor in depression. Biological Psychiatry, 86(10), 738–748. https://doi.org/10.1016/j.biopsych.2019.05.020
  • Kubová, H., Bendová, Z., Moravcová, S., Pačesová, D., Rocha, L. L., & Mareš, P. (2018). Neonatal Clonazepam administration induces long-lasting changes in glutamate receptors. Frontiers in Molecular Neuroscience, 11, 382. https://doi.org/10.3389/fnmol.2018.00382
  • Landgraf, D., Long, J. E., Proulx, C. D., Barandas, R., Malinow, R., & Welsh, D. K. (2016). Genetic disruption of Circadian rhythms in the suprachiasmatic nucleus causes helplessness, behavioral despair, and anxiety-like behavior in mice. Biological Psychiatry, 80(11), 827–835. https://doi.org/10.1016/j.biopsych.2016.03.1050
  • Mallei, A., Ieraci, A., & Popoli, M. (2018). Chronic social defeat stress differentially regulates the expression of BDNF transcripts and epigenetic modifying enzymes in susceptible and resilient mice. World Journal of Biological Psychiatry., 19, 1–12.
  • Mang, G. M., La Spada, F., Emmenegger, Y., Chappuis, S., Ripperger, J. A., Albrecht, U., & Franken, P. (2016). Altered sleep homeostasis in Rev-erbα knockout mice. Sleep, 39(3), 589–601. https://doi.org/10.5665/sleep.5534
  • Manz, K. M., Levine, W. A., Seckler, J. C., Iskander, A. N., & Reich, C. G. (2018). A novel adolescent chronic social defeat model: Reverse-Resident-Intruder Paradigm (r RIP) in male rats. Stress, 21(2), 169–178. https://doi.org/10.1080/10253890.2017.1423285
  • Milin, J. (1998). Stress-reactive response of the gerbil pineal gland: Concretion genesis. General and Comparative Endocrinology, 110(3), 237–251. https://doi.org/10.1006/gcen.1998.7069
  • Milin, J., Demajo, M., & Todorovic, V. (1996). Rat pinealocyte reactive response to a long-term stress inducement. Neuroscience, 73(3), 845–854. https://doi.org/10.1016/0306-4522(96)00014-0
  • Moreno-Rius, J. (2019). The cerebellum under stress. Frontiers in Neuroendocrinology, 54, 100774. https://doi.org/10.1016/j.yfrne.2019.100774
  • Murinova, J., Hlavacova, N., Chmelova, M., & Riecansky, I. (2017). The evidence for altered BDNF expression in the brain of rats reared or housed in social isolation: A systematic review. Frontiers in Behavioral Neuroscience., 11, 101. https://doi.org/10.3389/fnbeh.2017.00101
  • Natsubori, A., Honma, K., & Honma, S. (2014). Dual regulation of clock gene Per2 expression in discrete brain areas by the circadian pacemaker and methamphetamine-induced oscillator in rats. The European Journal of Neuroscience, 39(2), 229–240. https://doi.org/10.1111/ejn.12400
  • Niraula, A., Wang, Y., Godbout, J. P., & Sheridan, J. F. (2018). Corticosterone production during repeated social defeat causes monocyte mobilization from the bone marrow, glucocorticoid resistance, and neurovascular adhesion molecule expression. The Journal of Neuroscience : The Oscience, 38(9), 2328–2340. https://doi.org/10.1523/JNEUROSCI.2568-17.2018
  • Norman, K. J., Seiden, J. A., Klickstein, J. A., Han, X., Hwa, L. S., De Bold, J. F., & Miczek, K. A. (2015). Social stress and escalated drug self-administration in mice I. Alcohol and corticosterone. Psychopharmacology, 232(6), 991–1001. https://doi.org/10.1007/s00213-014-3733-9
  • Patki, G., Solanki, N., Atrooz, F., Allam, F., & Salim, S. (2013). Depression, anxiety-like behavior and memory impairment are associated with increased oxidative stress and inflammation in a rat model of social stress. Brain Research., 1539, 73–86. https://doi.org/10.1016/j.brainres.2013.09.033
  • Pizarro, A., Hayer, K., Lahens, N. F., Hogenesch, J. B., & Circa, D. B. (2012). A database of mammalian circadian gene expression pro-files. Nucleic Acids Research, 41(D1), D1009–D1013. https://doi.org/10.1093/nar/gks1161
  • Qiao, H., Li, M. X., Xu, C., Chen, H. B., An, S. C., & Ma, X. M. (2016). Dendritic spines in depression: What we learned from animal models. Neural Plasticity, 2016, 8056370. https://doi.org/10.1155/2016/8056370
  • Radha, E., Shankaraiah, K., Halberg, F., & Bhaskaran, D. (1985). Developmental, circadian and aging aspects of dopamine, norepinephrine and 5-HT in rat brain regions. In P. H. Redfern, I. Campbell, J. A. Xavier, & K. F. Martin (Eds.), Circadian Rhythms in the Central Nervous System, Proceedings of the IX Conference IUPHAR, SAT Symposium (pp. 199–209). Macmillan.
  • Razzoli, M., Domenici, E., Carboni, L., Rantamaki, T., Lindholm, J., Castrén, E., & Arban, R. (2011). A role for BDNF/Trk B signaling in behavioral and physiological consequences of social defeat stress. Genes, Brain and Behavior, 10(4), 424–433. https://doi.org/10.1111/j.1601-183X.2011.00681.x
  • Roybal, K., Theobold, D., Graham, A., Di Nieri, J. A., Russo, S. J., Krishnan, V., Chakravarty, S., Peevey, J., Oehrlein, N., Birnbaum, S., Vitaterna, M. H., Orsulak, P., Takahashi, J. S., Nestler, E. J., Carlezon, W. A., Jr., & Mc Clung, C. A. (2007). Mania-like behavior induced by disruption of CLOCK. Proceedings of the National Academy of Sciences of the United States of America, 104(15), 6406–6411. https://doi.org/10.1073/pnas.0609625104
  • Schaaf, M. J., Duurland, R., de Kloet, E. R., & Vreugdenhil, E. (2000). Circadian variation in BDNF m RNA expression in the rat hippocampus. Molecular Brain Research, 75(2), 342–344. https://doi.org/10.1016/S0169-328X(99)00314-9
  • Sengupta, S., Yang, G., O’Donnell, J. C., Hinson, M. D., McCormack, S. E., Falk, M. J., La, P., Robinson, M. B., Williams, M. L., Yohannes, M. T., Polyak, E., Nakamaru-Ogiso, E., & Dennery, P. A. (2016). The circadian gene Rev-erbα improves cellular bioenergetics and provides preconditioning for protection against oxidative stress. Free Radical Biology & Medicine, 93, 177–189. https://doi.org/10.1016/j.freeradbiomed.2016.02.004
  • Spencer, S., Falcon, E., Kumar, J., Krishnan, V., Mukherjee, S., Birnbaum, S. G., & Mc Clung, C. A. (2013). Circadian genes period 1 and period 2 in the nucleus accumbens regulate anxiety-related behavior. The European Journal of Neuroscience, 37(2), 242–250. https://doi.org/10.1111/ejn.12010
  • Tahara, Y., & Shibata, S. (2018). Entrainment of the mouse circadian clock: Effects of stress, exercise, and nutrition, Free Radic. Free Radical Biology & Medicine, 119, 129–138. https://doi.org/10.1016/j.freeradbiomed.2017.12.026
  • Torra, I. P., Tsibulsky, V., Delaunay, F., Saladin, R., Laudet, V., Fruchart, J. C., Kosykh, V., & Staels, B. (2000). Circadian and glucocorticoid regulation of Rev-erbalpha expression in liver. Endocrinology, 141(10), 3799–3806. https://doi.org/10.1210/endo.141.10.7708
  • Vasconcelos, M., Stein, D. J., & de Almeida, R. M. (2015). Social defeat protocol and relevant biomarkers, implications for stress response physiology, drug abuse, mood disorders and individual stress vulnerability: A systematic review of the last decade. Trends in Psychiatry and Psychotherapy, 37(2), 51–66. https://doi.org/10.1590/2237-6089-2014-0034
  • Vodička, M., Ergang, P., Mikulecká, A., Řeháková, L., Klusoňová, P., Makal, J., Soták, M., Musílková, J., Zach, P., & Pácha, J. (2014). Regulation of 11β-hydroxysteroid dehydrogenase type 1 and 7α-hydroxylase CYP7B1 during social stress. PLoS One, 9(2), e89421. https://doi.org/10.1371/journal.pone.0089421
  • Wyse, C. A., & Coogan, A. N. (2010). Impact of aging on diurnal expression patterns of CLOCK and BMAL1 in the mouse brain. Brain Research, 1337, 21–31. https://doi.org/10.1016/j.brainres.2010.03.113
  • Yi, L. T., Luo, L., Wu, Y. J., Liu, B. B., Liu, X. L., Geng, D., & Liu, Q. (2015). Circadian variations in behaviors, BDNF and cell proliferation in depressive mice. Metabolic Brain Disease, 30(6), 1495–1503. https://doi.org/10.1007/s11011-015-9710-0
  • Yoshida, K., Hashiramoto, A., Okano, T., Yamane, T., Shibanuma, N., & Shiozawa, S. (2013). TNF-α modulates expression of the circadian clock gene Per2 in rheumatoid synovial cells. Scandinavian Journal of Rheumatology, 42(4), 276–280. https://doi.org/10.3109/03009742.2013.765031
  • Yuan, T. F., & Slotnick, B. M. (2014). Roles of olfactory system dysfunction in depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 54, 26–30. https://doi.org/10.1016/j.pnpbp.2014.05.013

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