Publication Cover
Stress
The International Journal on the Biology of Stress
Volume 10, 2007 - Issue 1
184
Views
3
CrossRef citations to date
0
Altmetric
Original

Differential vascular adaptive response to stress exposure in male and female rats: Role of gonadal hormones and endothelial cells

&
Pages 27-36 | Received 24 Aug 2006, Accepted 18 Nov 2006, Published online: 07 Jul 2009

References

  • Arteche E, Strippoli G, Loirand G, Pacaud P, Candenas L, Molto JC, Souto L, Fernandez J, Norte M, Martin JD, Savineau JP. An analysis of the mechanisms involved in the okadaic acid induced contraction of the estrogen-primed rat uterus. J Pharmacol Exp Ther 1997; 282(1)201–207
  • Ba ZF, Yokoyama Y, Toth B, Rue LW, 3rd, Bland KI, Chaudry IH. Gender differences in small intestinal endothelial function: Inhibitory role of androgens. Am J Physiol Gastrointest Liver Physiol 2004; 286(3)G452–G457
  • Calderone V, Baragatti B, Breschi MC, Nieri P, Martinotti E. Hormonal influence on the release of endothelial nitric oxide: Gender related dimorphic sensitivity of rat aorta for noradrenaline. J Pharm Pharmacol 2002; 54(4)523–528
  • Cankar K, Finderle Z. Gender differences in cutaneous vascular and autonomic nervous response to local cooling. Clin Auton Res 2003; 13(3)214–220
  • Cignarella A, Bolego C, Pinna C, Zanardo R, Nardi F, Zancan V, Puglisi L. Androgen deprivation, estrogen treatment and vascular function in male rat aorta. Naunyn Schmiedebergs Arch Pharmacol 2000; 361(2)166–172
  • Conde MV, Marín J, Fernandez-Criado C, Balfagón G. Regulation of beta-adrenoceptor-mediated relaxation of the rat aorta is modulated by endogenous ovarian hormones. Clin Sci 2000; 98(4)381–387
  • Cordellini S, Vassilieff VS. Decreased endothelium-dependent vasoconstriction in acuted stressed rats is potentiated by previous chronic stress. Nitric oxide involvement. Gen Pharmacol 1998; 30(1)79–83
  • Cordellini S, Carvalho MHC, Scivoletto R, Fortes ZB, Nigro D. Indirect evidence for an endothelium-derived contracting factor in aorta of deoxycorticosterone acetate-salt hypertensive rats. J Hypertens 1990; 8(11)53–60
  • Cordellini S, Novo R, Lanza U, Jr. Exposure to stress. Differential vascular adaptive response in spontaneously hypertensive and Wistar rats: Role of nitric oxide, and prehypertensive and hypertensive states. Life Sci 2006; 79: 646–653
  • Crews JK, Khalil RA. Gender-specific inhibition of Ca++ entry mechanisms of arterial vasoconstriction by sex hormones. Clin Exp Pharmacol Physiol 1999; 26(9)707–715
  • Dar DE, Zinder O. Short-term effect of steroids on catecholamines secretion from bovine adrenal medulla chromaffin cells. Neuropharmacology 1997; 36(11/12)1783–1788
  • Delgado JL, Landeras J, Carbonell LF, Parilla JJ, Abad L, Quesada T, Fiol G, Hernandez I. Effect of n-acetylcisteine on vascular endothelium function in aorta from oophorectomized rats. Gen Pharmacol 1999; 32(1)23–27
  • Duckles SP, Krause DN, Miller VM. Effects of gonadal steroids on vascular function. J Pharmacol Exp Ther 1986; 279(1)1–3
  • Evans JM, Ziegler MG, Patwardhan AR, Ott JB, Kim CS, Leonelli FM, Knapp CF. Gender differences in autonomic cardiovascular regulation: Spectral, hormonal, and hemodynamic indexes. J Appl Physiol 2001; 91(6)2611–2618
  • Ford JA, Clark SG, Walters EM, Wheeler MB, Hurley WL. Estrogenic effects of genistein on reproductive tissues of ovariectomized gillts. J Anim Sci 2006; 84(4)834–842
  • Garcia-Villalón AL, Sanz E, Monge L, Fernandez N, Martinez MA, Climent B, Dieguez G. Vascular reactivity to vasopressin during diabetes: Gender and regional differences. Eur J Pharmacol 2003; 459(2/3)247–254
  • Glenn TC, Krause DN, Duckles SP. Vascular responses to neuropeptide Y are greater in female than male rats. Naunyn Schmiedebergs Arch Pharmacol 1997; 355(1)111–118
  • Handa RJ, Nunley KM, Lorens SA, Louie JP, Mcgivern RF, Bollnow MR. Androgen regulation of adrenocorticotropin and corticosterone secretion in the male rat following novelty and foot shock stressors. Physiol Behav 1994; 55(1)117–124
  • Hutchison SJ, Sudhir K, Chou TM, Chatterjee K. Sex hormones and vascular reactivity. Herz 1997; 22(3)141–150
  • Isles CG, Hole DJ, Hawthorne VM, Lever AF. Relation between coronary risk and coronary mortality in women of renfrew and paisley survey: Comparison with men. Lancet 1992; 339(8795)702–706
  • Jansakul C. Effect of swimming on vascular reactivity to phenylephrine and KCl in male rats. Br J Pharmacol 1995; 115(4)587–594
  • Kanashiro CA, Khalil RA. Gender-related distinctions in protein kinase C activity in rat vascular smooth muscle. Am J Cell Physiol 2001; 280(1)C34–C45
  • Kauser K, Rubanyi GM. Gender difference in endothelial dysfunction in the aorta of spontaneously hypertensive rats. Hypertension 1995; 4(1)517–523
  • Khalil RA. Sex hormones as potential modulators of vascular function in hypertension. Hypertension 2005; 46: 249–254
  • Knoll J, Miklya I, Knoll B, Dilló J. Sexual hormones terminate in the rat the significantly enhanced catecholaminergic/serotoninergic tone in the brain characteristic to the post-weaning period. Life Sci 2000; 67: 765–773
  • Lapshin AV, Manukhina EB, Meerson FZ. Adaptation to short stress exposures prevents the enhancement of the endothelium-dependent reactions of the aorta in myocardial infarct. Fiziol Zh Im I M Sechenova 1991; 77(3)70–78
  • Levenson J, Pessana F, Gariepy J, Armentano R, Simon A. Gender differences in wall shear-mediated brachial artery vasoconstriction and vasodilation. J Am Coll Cardiol 2001; 38(6)1668–1674
  • Lund TD, Hinds LR, Handa RJ. The androgen 5alpha-dihydrotestosterone and its metabolite 5alpha-androstan-3beta, 17beta-diol inhibit the hypothalamo–pituitary–adrenal response to stress by acting through estrogen receptor beta-expressing neurons in the hypothalamus. J Neurosci 2006; 26(5)1448–1456
  • Ma I, Yu Z, Xiao S, Thadani U, Robinson CP, Patterson E. Supersensitivity to serotonin- and histamine induced arterial contraction following ovariectomy. Eur J Pharmacol 2000; 359(2/3)191–200
  • Milakofsky L, Harris N, Vogel WH. Effects of repeated stress on plasma arginine levels in young and old rats. Physiol Behav 1993; 54: 725–728
  • Minshall RD, Miyagawa K, Chadwick CC, Novy MJ, Hermsmeyer K. In vitro modulation of primate coronary vascular muscle cell reactivity by ovarian steroid hormones. FASEB J 1998; 12(13)1419–1529
  • Morschl E, Bretus I, Nemcsik J, László F, Pávó I. Estrogen-mediated up-regulation of the Ca-dependent constitutive nitric oxide synthase in the rat aorta and heart. Life Sci 2000; 68: 49–55
  • Navarro-Oliveira CM, Vassilieff VS, Cordellini S. The sympathetic adrenomedullary system, but not the hypothalamic–pituitary–adrenal axis, participates in aorta adaptive response to stress: Nitric oxide involvement. J Auton Nerv Syst 2000; 83(3)140–147
  • Nevala R, Paakkari I, Tarkkila L, Vapaatalo H. The effects of male gender and female sex hormone deficiency on the vascular responses of the rat in vitro. J Physiol Pharmacol 1996; 47(3)425–432
  • Ogilvie KM, Rivier C. Gender difference in hypothalamic–pituitary–adrenal axis responses to alcohol in the rat: Activational role of gonadal steroids. Brain Res 1997; 766(1/2)19–28
  • Ong PJ, Patrizi G, Chong WC, Webb CM, Hayward CS, Collins P. Testosterone enhances flow-mediated brachial artery reactivity in men with coronary artery disease. Am J Cardiol 2000; 85(2)269–272
  • Rees DD, Palmer RMJ, Schulz R, Hodson HF, Moncada S. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo. Br J Pharmacol 1990; 101(3)746–752
  • Reilly CM, Stopper VS, Mills TM. Androgens modulate the alpha-adrenergic responsiveness of vascular smooth muscle in the corpus cavernosum. J Androl 1997; 18(1)26–31
  • Robert R, Chagneau-Derrode C, Carretier M, Mauco G, Silvain C. Gender differences in vascular reactivity of aortas from rats with and without portal hypertension. J Gastroenterol Hepatol 2005; 20(6)890–894
  • Sanz E, Fernández N, Monge L, Martinez MA, Climent B, Dieguez G, Garcia-Villalon AL. Effects of diabetes on the vascular response to nitric oxide and constrictor prostanoids: Gender and regional differences. Life Sci 2003; 72(13)1537–1547
  • Seale JV, Wood SA, Atkinson HC, Bate E, Lightman SL, Ingram CD, Jessop DS, Harbuz MS. Gonadectomy reverses the sexually diergic patterns of circadian and stress-induced hypothalamo–pituitary–adrenal axis activity in male and female rats. J Neuroendocrinol 2004a; 16: 516–524
  • Seale JV, Wood SA, Atkinson HC, Harbuz MS, Lightman SL. Gonadal steroid replacement reverses gonadectomy-induced changes in the corticosterone pulse profile and stress-induced hypothalamic–pituitary–adrenal axis activity of male and female rats. J Neuroendocrinol 2004b; 16: 989–998
  • Selvaraj V, Zakroczymski MA, Naaz A, Mukai M, Doerge DR, Katzenellenbogen JA, Helferich WC, Cooke PS. Estrogenicity of the isoflavone metabolite equal on reproductive and non-reproductive organs in mice. Biol Reprod 2004; 71(3)966–972
  • Shoemaker JK, Hogeman CS, Khan M, Kimmerly DS, Sinoway LI. Gender affects sympathetic and hemodynamic response to postural stress. Am J Physiol 2001; 281(1)H2028–H2035
  • Stallone JN. Sex differences in nitric oxide-mediated attenuation of vascular reactivity to vasopressin are abolished by gonadectomy. Eur J Pharmacol 1994; 259(3)273–283
  • Vane JR. Inhibition of prostaglandin synthase as a mechanism of action for aspirin-like drugs. Nat New Biol 1971; 23(25)232–235
  • Viau V. Functional cross-talk between the hypothalamic–pituitary–gonadal and adrenal axes. J Neuroendocrinol 2002; 14(6)506–513
  • Viau V, Meaney MJ. Variations in the hypothalamic–pituitary–adrenal response to stress during the estrous cycle in the rat. Endocrinology 1991; 129(5)2503–2511
  • Villar IC, Francis S, Weeb A, Hobbs AJ, Ahluwalia A. Novel aspects of endothelium-dependent regulation of vascular tone. Kidney Int 2006; 70(5)840–853
  • Virdis A, Ghiadoni L, Pinto S, Lombardo M, Petraglia F, Gennazzani A, Buralli S, Taddei S, Salvetti A. Mechanisms responsible for endothelial dysfunction associated with acute estrogen deprivation in normotensive women. Circulation 2000; 101(19)2258–2263
  • Webb CR, Vander AJ, Henry JP. Increased vasodilator responses to acetylcholine in psychosocial hypertensive mice. Hypertension 1987; 9(3)268–276
  • Worboys S, Kotsopoulos D, Teede H, McGrath B, Davis SR. Evidence that parenteral testosterone may improve endothelium-dependent and independent vasodilation in postmenopausal women already receiving estrogen. J Clin Endocrinol Metab 2001; 86(1)158–161
  • Yue P, Chatterjee K, Beale C, Poole-Wilson PA, Collions P. Testosterone relaxes rabbit coronary arteries and aorta. Circulation 1995; 91(4)1154–1160
  • Zamorano B, Bruzzone ME, Martinez JI. Vascular smooth muscle reactivity to norepinephrine in ovariectomized rats: Relationship to vascular PGE2/PGF2 alpha ratio. Gen Pharmacol 1995; 26(7)1613–1618
  • Zysow BR, Kauser K, Lawn RM, Rubanyi GM. Effects of estrus cycle, ovariectomy, and treatment with estrogen, tamoxifen, and progesterone on apolipoprotein(a) gene expression in transgenic mice. Arterioscler Thromb Vasc Biol 1997; 17(9)1741–1745

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.