Gray and White Matter Brain Volume in Aged Rats Raised on n-3 Fatty Acid Deficient Diets

References

• Ahmad, A., Moriguchi, T. and Salem, N., Jr. (2002a ) “Decrease in neuron size in docosahexaenoic acid-deficient brain”, Pediatric Neurology 26, 210–218.
   PubMed Web of Science ®Google Scholar
• Ahmad, A., Murthy, M., Griener, R.S., Moriguchi, T. and Salem, N., Jr. (2002b ) “A decrease in cell size accompanies a loss of docosahexaenoate in the rat hippocampus”, Nutritional Neuroscience 5, 103–113.
   PubMed Web of Science ®Google Scholar
• Bothwell, S., Meredith, G.E., Phillips, J., Staunton, H., Doherty, C., Grigorenko, E., Glazier, S., Deadwyler, S.A., O’Donovan, C.A. and Farrell, M. (2001 ) “Neuronal hypertrophy in the neocortex of patients with temporal lobe epilepsy”, Journal of Neuroscience 21, 4789–4800.
   PubMed Web of Science ®Google Scholar
• Bourre, J.M., Durand, G., Erre, J-P. and Aran, J-M. (1999 ) “Changes I auditory brainstem responses in alpha-linolenic acid deficiency as a function of age in rats”, Audiology 38, 13–18.
   PubMedGoogle Scholar
• Catalan, J., Moriguchi, T., Slotnick, B., Murthy, M., Greiner, R.S. and Salem, N., Jr. (2002 ) “Cognitive deficits in docosahexaenoic acid-deficient rats”, Behavioral Neuroscience 116, 1022–1031.
   PubMed Web of Science ®Google Scholar
• Clandinin, M.T., Chappell, J.E., Leong, S., Heim, T., Swyer, P.R. and Chance, G.W. (1980a ) “Intrauterine fatty acid accretion rates in human brain, implications for fatty acid requirements”, Early Human Development 4, 121–129.
   PubMed Web of Science ®Google Scholar
• Clandinin, M.T., Chappell, J.E., Leong, S., Heim, T., Swyer, P.R. and Chance, G.W. (1980b ) “Extrauterine fatty acid accretion in infant brain, implications for fatty acid requirements”, Early Human Development 4, 131–138.
   PubMed Web of Science ®Google Scholar
• Faust, P.L., Su, H.M., Moser, A. and Moser, H.W. (2001 ) “The peroxisome deficient PEX2 Zellweger mouse, pathologic and biochemical correlates of lipid dysfunction”, Molecular Neuroscience 16, 289–297, discussion 317–321.
   PubMed Web of Science ®Google Scholar
• Favrelere, S., Stadelmann-Ingrand, S., Huguet, F., De Javel, D., Piriou, A., Tallineau, C. and Durand, G. (2000 ) “Age-related changes in ethanolamine glycerophospholipid fatty acid levels in rat frontal cortex and hippocampus”, Neurobiology of Aging 21, 653–660.
   PubMed Web of Science ®Google Scholar
• Gonzalalez, R.C. and Wintz, P. (1977) Digital Image Processing (Addison-Wesley, Reading, MA).
   Google Scholar
• Green, P. and Yavin, E. (1998 ) “Mechanisms of docosahexaenoic acid accretion in the fetal brain”, Journal of Neuroscience Research 52, 129–136.
   PubMed Web of Science ®Google Scholar
• Greiner, R.S., Moriguchi, T., Slotnick, B.M., Hutton, A. and Salem, N. (2001 ) “Olfactory discrimination deficits in n-3 fatty acid-deficient rats”, Physiology & Behavior 72, 379–385.
   PubMed Web of Science ®Google Scholar
• Hashimoto, M., Hossain, S., Shimada, T., Sugioka, K., Yamasaki, H., Fujii, Y., Ishibashi, Y., Oka, J-I. and Shido, O. (2002 ) “Docosahexaenoic acid provides protection from impairment of learning ability in Alzheimer’s disease model rats”, Journal ofNeurochemistry 81, 1084–1091.
   PubMed Web of Science ®Google Scholar
• Hommer, D., Momenan, R., Kaiser, E. and Rawlings, R. (2001 ) “Evidence for a gender-related effect of alcoholism on brain volumes”, American Journal of Psychiatry 58, 98–204.
   Google Scholar
• Ikemoto, A., Ohishi, M., Hata, N., Misawa, Y., Fujii, Y. and Okuyama, H. (2000 ) “Effect of n-3 fatty acid deficiency on fatty acid composition and metabolism of aminophospholipids in rat brain synaptosomes”, Lipids 35, 1107–1115.
   PubMed Web of Science ®Google Scholar
• Jeffrey, B.G., Mitchell, D.C., Hibbeln, J.R., Gibson, R.A., Chedester, A.L. and Salem, N., Jr. (2002 ) “Visual acuity and retinal function in infant monkeys fed long-chain PUFA”, Lipids 37, 839–848.
   PubMed Web of Science ®Google Scholar
• Martinez, M. (1992 ) “Tissue levels of polyunsaturated fatty acids during early human development”, Journal of Pediatrics 120, S129–S138.
   Google Scholar
• Martinez, M. (2001 ) “Restoring the DHA levels in the brains of Zellweger patients”, Journal of Molecular Neuroscience 16, 309–316, discussion 317–322.
   PubMed Web of Science ®Google Scholar
• Martinez, M. and Vazquez, E. (1998 ) “MRI evidence that docosahexaenoic acid ethyl ester improves myelination in generalized peroxisomal disorders”, Neurology 51, 26–32.
   PubMed Web of Science ®Google Scholar
• Martinez, M., Vazquez, E., Garcia-Silva, M.T., Manzanares, J., Bertran, J.M., Castello, F. and Mougan, I. (2000 ) “Therapeutic effects of docosahexaenoic acid ethyl ester in patients with generalized peroxisomal disorders”, American Journal of Clinical Nutrition 71, 376S-385S.
   PubMed Web of Science ®Google Scholar
• McGahon, B.M., Martin, D.S., Horrobin, D.F. and Lynch, M.A. (1999 ) “Age-related changes in synaptic function, analysis of the effect of dietary supplementation with omega-3 fatty acids”, Neuroscience 94, 305–314.
   PubMed Web of Science ®Google Scholar
• Mervis, R.F., Bachstetter, A., Waters, A., Ahmad, A., Moriguchi, T. and Salem, N. (2001) “Dietary deficiency of docosahexaenoic acid (DHA) impairs dendritic development in rat neocortex”, [Abstract, program number 256.18]. 31st Soc for Neurosci, San Diego, CA.
   Google Scholar
• Momenan, R., Hommer, D., Rawlings, R., Ruttimann, U., Kerich, M. and Rio, D. (1997 ) “Intensity-adaptive segmentation of single-echo T1-weighted resonance images”, Human Brain Mapping 5, 194–205.
   PubMed Web of Science ®Google Scholar
• Moriguchi, T., Greiner, R.S. and Salem, N., Jr. (2000 ) “Behavioral deficits associated with dietary induction of decreased brain docosahexaenoic acid concentration”, . Journal of Neurochemistry 75, 2563–2573.
   PubMed Web of Science ®Google Scholar
• Moriguchi, T., Loewke, J., Garrison, M., Catalan, J.N. and Salem, N., Jr. (2001 ) “Reversal of docosahexaenoic acid deficiency in the rat brain, retina, liver, and serum”, Journal ofLipid Research 42, 419–427.
   PubMed Web of Science ®Google Scholar
• Paxinos, G. and Watson, C. (1986) The Rat Brain in Stereotaxic Coordinates, 2nd Edn. (Academic Press, California).
   Google Scholar
• Reeves, P.G., Neil, F.H. and Fahey, G.C. (1993 ) “Committee report on the AIN-93 purified rodent diet”, Journal of Nutrition 123, 1939–1951.
   PubMed Web of Science ®Google Scholar
• Salem, N., Jr. (1989 ) “Omega-3 fatty acid, molecular and biochemical aspects ”, In: Spiller, G. and Scala, J., eds, New Protective Roles of Selected Nutrients in Human Nutrition (Alan R. Liss, New York).
   Google Scholar
• Salem, N., Jr., Litman, B., Kim, H.Y. and Gawrisch, K. (2001a ) “Mechanisms of action of docosahexaenoic acid in the nervous system”, Lipids 36, 945–959.
   PubMed Web of Science ®Google Scholar
• Salem, N., Jr., Moriguchi, T., Greiner, R.S., McBride, K., Ahmad, A., Catalan, J.N. and Slotnick, B. (2001b ) “Alterations in brain function after loss of docosahexaenoate due to dietary restriction of n-3 fatty acids”, Journal ofMolecular Neuroscience 16, 299–307, discussion 317–321.
   PubMed Web of Science ®Google Scholar
• Schiefermeier, M. and Yavin, E. (2002 ) “n-3 Deficient and docosahexaenoic acid-enriched diets during critical periods of the developing prenatal rat brain”, Journal of Lipid Research 43, 124–131.
   PubMed Web of Science ®Google Scholar
• Sweet, R.A., Pierri, J.N., Auh, S., Sampson, A.R. and Lewis, D.A. (2003 ) “Reduced pyramidal cell somal volume in auditory association cortex of subjects with schizophrenia”, Neuropsychopharmacology 28, 599–609.
   PubMed Web of Science ®Google Scholar
• Uauy, R., Mena, P. and Rojas, C. (2000 ) “Essential fatty acids in early life, structural and functional role”, Proceedings of the Nutritional Society 59, 3–15.
   PubMed Web of Science ®Google Scholar
• Wainwright, P.E. (2002 ) “Essential fatty acids and brain function, a developmental perspective on mechanisms”, Proceedings ofthe Nutritional Society 61, 61–69.
   PubMed Web of Science ®Google Scholar
• Weisinger, H.S., Armitage, J.A., Jeffrey, B.G., Mitchell, D.C., Moriguchi, T., Sinclair, A.J., Weisinger, R.S. and Salem, N., Jr. (2002 ) “Retinal sensitivity loss in third-generation n-3 PUFA- deficient rats”, Lipids 37, 759–765.
   PubMed Web of Science ®Google Scholar
• Yamamoto, N., Okaniwa, Y., Mori, S., Nomura, M. and Okuyama, H. (1991a) “Related effects of a high-linoleate and a high-alpha-linolenate diet on the learning ability of aged rats. Evidence against an autoxidation-related lipid peroxide theory of aging”, . Journal of Gerontology 46, B17–B22.
   PubMedGoogle Scholar
• Yamamoto, N., Okaniwa, Y., Mori, S., Nomura, M. and Okuyama, H. (1991b) “Effects of high-linoleate and a high-α-linolenate diet on the learning ability of aged rats. Evidence against an autooxidation-related lipid peroxide theory of aging”, Journal of Gerontology 46, B17–B22.
   PubMedGoogle Scholar
• Yehuda, S., Rabinovitz, S., Carasso, R.L. and Mostofsky, D.I. (2002 ) “The role of polyunsaturated fatty acids in restoring the aging neuronal membrane”, Neurobiology of Aging 23, 843– 853.
   PubMed Web of Science ®Google Scholar