The role of calcium sensing receptors in GLP-1 and PYY secretion after acute intraduodenal administration of L-Tryptophan in rats

References

• Johnstone AM. Safety and efficacy of high-protein diets for weight loss. Proc Nutr Soc 2012;71(2):339–49. doi: 10.1017/S0029665112000122
   PubMed Web of Science ®Google Scholar
• Halton TL, Hu FB. The effects of high protein diets on thermogenesis, satiety and weight loss: a critical review. J Am Coll Nutr 2004;23(5):373–85. doi: 10.1080/07315724.2004.10719381
   PubMed Web of Science ®Google Scholar
• Jahan-Mihan A, Luhovyy BL, El Khoury D, Anderson GH. Dietary proteins as determinants of metabolic and physiologic functions of the gastrointestinal tract. Nutrients 2011;3(5):574–603. doi: 10.3390/nu3050574
   PubMed Web of Science ®Google Scholar
• Spreckley E, Murphy KG. The L-cell in nutritional sensing and the regulation of appetite. Front Nutr 2015;2:23. doi: 10.3389/fnut.2015.00023
   PubMedGoogle Scholar
• Ojha U. Protein-induced satiation and the calcium-sensing receptor. Diabetes Metab Syndr Obes 2018;11:45–51. doi: 10.2147/DMSO.S156597
   PubMed Web of Science ®Google Scholar
• Bruen CM, O’Halloran F, Cashman KD, Giblin L. The effects of food components on hormonal signalling in gastrointestinal enteroendocrine cells. Food Funct 2012;3:1131–43. doi: 10.1039/c2fo30086a
   PubMed Web of Science ®Google Scholar
• Conigrave AD, Brown EM. Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology. Am J Physiol Gastrointest Liver Physiol 2006;291:G753–61. doi: 10.1152/ajpgi.00189.2006
   PubMed Web of Science ®Google Scholar
• Liou AP, Sei Y, Zhao X, Feng J, Lu X, Thomas C, et al. The extracellular calcium-sensing receptor is required for cholecystokinin secretion in response to l-phenylalanine in acutely isolated intestinal I cells. Am J Physiol Gastrointest Liver Physiol 2011;300(4):G538–46. doi: 10.1152/ajpgi.00342.2010
   PubMed Web of Science ®Google Scholar
• Mace OJ, Schindler M, Patel S. The regulation of K- and L-cell activity by GLUT2 and the calcium-sensing receptor CasR in rat small intestine. J Physiol 2012;590(12):2917–36. doi: 10.1113/jphysiol.2011.223800
   PubMed Web of Science ®Google Scholar
• Brennan S, Davies TS, Schepelmann M, Riccardi D. Emerging roles of the extracellular calcium-sensing receptor in nutrient sensing: control of taste modulation and intestinal hormone secretion. Br J Nutr 2014;111(Suppl 1):S16–22. doi: 10.1017/S0007114513002250
   PubMedGoogle Scholar
• Geng Y, Mosyak L, Kurinov I, Zuo H, Sturchler E, Cheng TC, et al. Structural mechanism of ligand activation in human calcium-sensing receptor. Elife 2016;5:e13662. doi: 10.7554/eLife.13662
   PubMed Web of Science ®Google Scholar
• Meyer-Gerspach AC, Häfliger S, Meili J, Doody A, Rehfeld JF, Drewe J, et al. Effect of L-tryptophan and L-leucine on gut hormone secretion, appetite feelings and gastric emptying rates in lean and non-diabetic obese participants: a randomized, double-blind, parallel-group trial. PLoS One 2016;11(11):e0166758. doi: 10.1371/journal.pone.0166758
   PubMed Web of Science ®Google Scholar
• Steinert RE, Ullrich SS, Geary N, Asarian L, Bueter M, Horowitz M, et al. Comparative effects of intraduodenal amino acid infusions on food intake and gut hormone release in healthy males. Physiol Rep 2017;5(21):e13492. doi: 10.14814/phy2.13492
   PubMed Web of Science ®Google Scholar
• Zhao X, Xian Y, Wang C, Ding L, Meng X, Zhu W, et al. Calcium-sensing receptor-mediated L-tryptophan-induced secretion of cholecystokinin and glucose-dependent insulinotropic peptide in swine duodenum. J Vet Sci 2018;19(2):179–87. doi: 10.4142/jvs.2018.19.2.179
   PubMed Web of Science ®Google Scholar
• Muramatsu M, Hira T, Mitsunaga A, Sato E, Nakajima S, Kitahara Y, et al. Activation of the gut calcium-sensing receptor by peptide agonists reduces rapid elevation of plasma glucose in response to oral glucose load in rats. Am J Physiol Gastrointest Liver Physiol 2014;306(12):G1099–107. doi: 10.1152/ajpgi.00155.2014
   PubMed Web of Science ®Google Scholar
• Steinert RE, Luscombe-Marsh ND, Little TJ, Standfield S, Otto B, Horowitz M, et al. Effects of intraduodenal infusion of L-tryptophan on ad libitum eating, antropyloroduodenal motility, glycemia, insulinemia, and gut peptide secretion in healthy men. J Clin Endocrinol Metab 2014;99(9):3275–84. doi: 10.1210/jc.2014-1943
   PubMed Web of Science ®Google Scholar
• Xian Y, Zhao X, Wang C, Kang C, Ding L, Zhu W, et al. Phenylalanine and tryptophan stimulate gastrin and somatostatin secretion and H+-K+-ATPase activity in pigs through calcium-sensing receptor. Gen Comp Endocrinol 2018;267:1–8. doi:10.1016/j.ygcen.2018.05.022 doi: 10.1016/j.ygcen.2018.05.022
   Google Scholar
• Ueda Y, Iwakura H, Bando M, Doi A, Ariyasu H, Inaba H, et al. Differential role of GPR142 in tryptophan-mediated enhancement of insulin secretion in obese and lean mice. PLoS One 2018;13(6):e0198762. doi: 10.1371/journal.pone.0198762
   PubMed Web of Science ®Google Scholar
• Nemeth EF, Delmar EG, Heaton WL, Miller MA, Lambert LD, Conklin RL, et al. Calcilytic compounds: potent and selective Ca2+ receptor antagonists that stimulate secretion of parathyroid hormone. J Pharmacol Exp Ther 2001;299(1):323–31.
   PubMed Web of Science ®Google Scholar
• Nauck MA, Niedereichholz U, Ettler R, Holst JJ, Orskov C, Ritzel R, et al. Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans. Am J Physiol Endocrinol Metab 1997;273:E981–8. doi: 10.1152/ajpendo.1997.273.5.E981
   PubMed Web of Science ®Google Scholar
• Meeran K, O’Shea D, Edwards CM, Turton MD, Heath MM, Gunn I, et al. Repeated intracerebroventricular administration of glucagon-like peptide-1-(7–36) amide or exendin-(9–39) alters body weight in the rat. Endocrinology 1999;140(1):244–50. doi: 10.1210/endo.140.1.6421
   PubMed Web of Science ®Google Scholar
• Reimann F, Williams L, da Silva Xavier G, Rutter GA, Gribble FM. Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells. Diabetologia 2004;47(9):1592–601. doi: 10.1007/s00125-004-1498-0
   PubMed Web of Science ®Google Scholar
• van den Broek M, de Heide LJM, Emous M, Wijma RB, Veeger NJGM, Wolthuis A, et al. Satiety and gastrointestinal hormones during a mixed meal tolerance test after gastric bypass surgery: association with plasma amino acid concentrations. Surg Obes Relat Dis 2018. pii:S1550-7289(18)30258-2. doi:10.1016/j.soard.2018.05.010.
   PubMed Web of Science ®Google Scholar
• Alamshah A, Spreckley E, Norton M, Kinsey-Jones JS, Amin A, Ramgulam A, et al. L-phenylalanine modulates gut hormone release and glucose tolerance and suppresses food intake through the calcium-sensing receptor in rodents. Int J Obes (Lond) 2017;41(11):1693–701. doi: 10.1038/ijo.2017.164
   PubMed Web of Science ®Google Scholar
• Tolhurst G, Zheng Y, Parker HE, Habib AM, Reimann F, Gribble FM. Glutamine triggers and potentiates glucagon-like peptide-1 secretion by raising cytosolic Ca2+ and cAMP. Endocrinology 2011;152:405–13. doi: 10.1210/en.2010-0956
   PubMed Web of Science ®Google Scholar
• Feng J, Petersen CD, Coy DH, Jiang JK, Thomas CJ, Pollak MR, et al. Calcium-sensing receptor is a physiologic multimodal chemosensor regulating gastric G-cell growth and gastrin secretion. Proc Natl Acad Sci USA 2010;107(41):17791–6. doi: 10.1073/pnas.1009078107
   PubMed Web of Science ®Google Scholar
• MacLeod RJ. A new role for the extracellular calcium-sensing receptor demonstrated by using CCK-eGFP BAC mice. Am J Physiol Gastrointest Liver Physiol 2011;300(4):G526–7. doi: 10.1152/ajpgi.00029.2011
   PubMed Web of Science ®Google Scholar
• Tsiolakis D, Marks V. The differential effect of intragastric and intravenous tryptophan on plasma glucose, insulin, glucagon, GLI and GIP in the fasted rat. Horm Metab Res 1984;16(5):226–9. doi: 10.1055/s-2007-1014752
   PubMed Web of Science ®Google Scholar
• Ayaso R, Ghattas H, Abiad M, Obeid O. Meal pattern of male rats maintained on amino acid supplemented diets: the effect of tryptophan, lysine, arginine, proline, and threonine. Nutrients 2014;6(7):2509–22. doi: 10.3390/nu6072509
   PubMed Web of Science ®Google Scholar
• Gartner SN, Aidney F, Klockars A, Prosser C, Carpenter EA, Isgrove K, et al. Intragastric preloads of l-tryptophan reduce ingestive behavior via oxytocinergic neural mechanisms in male mice. Appetite 2018;125:278–86. doi: 10.1016/j.appet.2018.02.015
   PubMed Web of Science ®Google Scholar
• Chimerel C, Emery E, Summers DK, Keyser U, Gribble FM, Reimann F. Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells. Cell Rep 2014;9(4):1202–8. doi: 10.1016/j.celrep.2014.10.032
   PubMed Web of Science ®Google Scholar
• Krishnan S, Ding Y, Saedi N, Choi M, Sridharan GV, Sherr DH, et al. Gut microbiota-derived tryptophan metabolites modulate inflammatory response in hepatocytes and macrophages. Cell Rep 2018;23(4):1099–111. doi: 10.1016/j.celrep.2018.03.109
   PubMed Web of Science ®Google Scholar
• Wang Y, Chandra R, Samsa LA, Gooch B, Fee BE, Cook JM, et al. Amino acids stimulate cholecystokinin release through the Ca2+-sensing receptor. Am J Physiol Gastrointest Liver Physiol 2011;300(4):G528–37. doi: 10.1152/ajpgi.00387.2010
   Google Scholar
• Diakogiannaki E, Pais R, Tolhurst G, Parker HE, Horscroft J, Rauscher B, et al. Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor. Diabetologia 2013;56:2688–96. doi: 10.1007/s00125-013-3037-3
   PubMed Web of Science ®Google Scholar
• Pais R, Gribble FM, Reimann F. Signalling pathways involved in the detection of peptones by murine small intestinal enteroendocrine L-cells. Peptides 2016;77:9–15. doi: 10.1016/j.peptides.2015.07.019
   PubMed Web of Science ®Google Scholar
• Hira T, Nakajima S, Eto Y, Hara H. Calcium-sensing receptor mediates phenylalanine-induced cholecystokinin secretion in enteroendocrine STC-1 cells. FEBS J 2008;275(18):4620–6. doi: 10.1111/j.1742-4658.2008.06604.x
   PubMed Web of Science ®Google Scholar
• Joshi S, Tough IR, Cox HM. Endogenous PYY and GLP-1 mediate l-glutamine responses in intestinal mucosa. Br J Pharmacol 2013;170(5):1092–101. doi: 10.1111/bph.12352
   PubMed Web of Science ®Google Scholar
• Leech CA, Habener JF. Regulation of glucagon-like peptide-1 receptor and calcium-sensing receptor signaling by L-histidine. Endocrinology 2003;144(11):4851–8. doi: 10.1210/en.2003-0498
   PubMed Web of Science ®Google Scholar
• Squires PE, Harris TE, Persaud SJ, Curtis SB, Buchan AM, Jones PM. The extracellular calcium-sensing receptor on human beta-cells negatively modulates insulin secretion. Diabetes 2000;49(3):409–17. doi: 10.2337/diabetes.49.3.409
   PubMed Web of Science ®Google Scholar
• Gray E, Muller D, Squires PE, Asare-Anane H, Huang GC, Amiel S, et al. Activation of the extracellular calcium-sensing receptor initiates insulin secretion from human islets of langerhans: involvement of protein kinases. J Endocrinol 2006;190(3):703–10. doi: 10.1677/joe.1.06891
   PubMed Web of Science ®Google Scholar
• Jones PM, Kitsou-Mylona I, Gray E, Squires PE, Persaud SJ. Expression and function of the extracellular calcium-sensing receptor in pancreatic beta-cells. Arch Physiol Biochem 2007;113(3):98–103. doi: 10.1080/13813450701531185
   PubMedGoogle Scholar
• Rybczynska A, Marchwinska A, Dys A, Boblewski K, Lehmann A, Lewko B. Activity of the calcium-sensing receptor influences blood glucose and insulin levels in rats. Pharmacol Rep 2017;69(4):709–13. doi: 10.1016/j.pharep.2017.01.034
   PubMed Web of Science ®Google Scholar
• Lin HV, Efanov AM, Fang X, Beavers LS, Wang X, Wang J, et al. GPR142 controls tryptophan-induced insulin and incretin hormone secretion to improve glucose metabolism. PLoS One 2016;11(6):e0157298. doi: 10.1371/journal.pone.0157298
   PubMed Web of Science ®Google Scholar
• Oya M, Suzuki H, Watanabe Y, Sato M, Tsuboi T. Amino acid taste receptor regulates insulin secretion in pancreatic β-cell line MIN6 cells. Genes Cells 2011;16(5):608–16. doi: 10.1111/j.1365-2443.2011.01509.x
   PubMed Web of Science ®Google Scholar
• Parkash J, Asotra K. L-histidine sensing by calcium sensing receptor inhibits voltage-dependent calcium channel activity and insulin secretion in β-cells. Life Sci 2011;88(9-10):440–6. doi: 10.1016/j.lfs.2010.12.022
   PubMed Web of Science ®Google Scholar
• Ryan AT, Luscombe-Marsh ND, Saies AA, Little TJ, Standfield S, Horowitz M, et al. Effects of intraduodenal lipid and protein on gut motility and hormone release, glycemia, appetite, and energy intake in lean men. Am J Clin Nutr 2013;98(2):300–11. doi: 10.3945/ajcn.113.061333
   PubMed Web of Science ®Google Scholar
• Greeley Jr GH, Hashimoto T, Izukura M, Gomez G, Jeng J, Hill FL, et al. A comparison of intraduodenally and intracolonically administered nutrients on the release of peptide-YY in the dog. Endocrinology 1989;125(4):1761–5. doi: 10.1210/endo-125-4-1761
   PubMed Web of Science ®Google Scholar
• Cho HJ, Robinson ES, Rivera LR, McMillan PJ, Testro A, Nikfarjam M, et al. Glucagon-like peptide 1 and peptide YY are in separate storage organelles in enteroendocrine cells. Cell Tissue Res 2014;357(1):63–9. doi: 10.1007/s00441-014-1886-9
   PubMed Web of Science ®Google Scholar
• Fu-Cheng X, Anini Y, Chariot J, Voisin T, Galmiche JP, Rozé C. Peptide YY release after intraduodenal, intraileal, and intracolonic administration of nutrients in rats. Pflugers Arch 1995;431(1):66–75. doi: 10.1007/BF00374378
   PubMed Web of Science ®Google Scholar
• Naslund E, Bogefors J, Skogar S, Grybäck P, Jacobsson H, Holst JJ, et al. GLP-1 slows solid gastric emptying and inhibits insulin, glucagon, and PYY release in humans. Am J Physiol Regul Integr Comp Physiol 1999;277(3):R910–6. doi: 10.1152/ajpregu.1999.277.3.R910
   Web of Science ®Google Scholar
• Inubushi T, Kamemura N, Oda M, Sakurai J, Nakaya Y, Harada N, et al. L-tryptophan suppresses rise in blood glucose and preserves insulin secretion in type-2 diabetes mellitus rats. J Nutr Sci Vitaminol (Tokyo) 2012;58(6):415–22. doi: 10.3177/jnsv.58.415
   PubMed Web of Science ®Google Scholar
• Ardiansyah Shirakawa H, Inagawa Y, Koseki T, Komai M. Regulation of blood pressure and glucose metabolism induced by L-tryptophan in stroke-prone spontaneously hypertensive rats. Nutr Metab (Lond) 2011;8(1):45–51. doi: 10.1186/1743-7075-8-45
   PubMedGoogle Scholar
• Ritze Y, Bardos G, Hubert A, Bohle M, Bischoff SC. Effect of tryptophan supplementation on diet-induced non-alcoholic fatty liver disease in mice. Br J Nutr 2014;112(1):1–7. doi: 10.1017/S0007114514000440
   PubMed Web of Science ®Google Scholar