Prevention of diet restriction induced hyperactivity but not body-weight reduction in rats co-treated with tryptophan: relationship with striatal serotonin and dopamine metabolism and serotonin-1A auto-receptor expression

References

• Fladung AK, Gron G, Grammer K, Herrnberger B, Schilly E, Grasteit S, et al. A neural signature of anorexia nervosa in the ventral striatal reward system. Am J Psychiatry. 2010;167(2):206–12.
   PubMed Web of Science ®Google Scholar
• Goldstein A, Gvion Y. Socio-demographic and psychological risk factors for suicidal behavior among individuals with anorexia and bulimia nervosa: a systematic review. J Affect Disord. 2019;245:1149–67.
   PubMed Web of Science ®Google Scholar
• Dobrescu SR, Dinkler L, Gillberg C, Råstam M, Gillberg C, Wentz E. Anorexia nervosa: 30-year outcome. Br J Psychiatry 216(2), 97–104. 2019: 1–8.
   Web of Science ®Google Scholar
• Strobel C, Quadflieg N, Voderholzer U, Naab S, Fichter MM. Short- and long-term outcome of males treated for anorexia nervosa: a review of the literature. Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity. 2018;23(5):541–52.
   PubMed Web of Science ®Google Scholar
• Dash S. The impact of genetic and cultural factors on anorexia and bulimia. Life Research. 2019;2(2):71–79.
   Google Scholar
• Baranowska B, Kochanowski J. Neuroendocrine aspects of anorexia nervosa and bulimia nervosa. Neuroendocrinol Lett. 2018;39(3):172–8.
   PubMed Web of Science ®Google Scholar
• Brodrick BB, Jacobs MA, McAdams CJ. Psychosis in anorexia nervosa: a case report and review of the literature. Psychosomatics. 2020;61(2):181–7.
   PubMed Web of Science ®Google Scholar
• Muller TD, Focker M, Holtkamp K, Herpertz-Dahlmann B, Hebebrand J. Leptin-mediated neuroendocrine alterations in anorexia nervosa: somatic and behavioral implications. Child Adolesc Psychiatr Clin N Am. 2009;18(1):117–29.
   PubMed Web of Science ®Google Scholar
• Treasure J, Eid L. Eating disorder animal model. Curr Opin Psychiatry. 2019;32(6):471–7.
   PubMed Web of Science ®Google Scholar
• Haleem DJ. Improving therapeutics in anorexia nervosa with tryptophan. Life Sci. 2017;178:87–93.
   PubMed Web of Science ®Google Scholar
• Yokokura M, Terada T, Bunai T, Nakaizumi K, Kato Y, Yoshikawa E, et al. Alterations in serotonin transporter and body image-related cognition in anorexia nervosa. NeuroImage: Clinical. 2019;23:101928.
   PubMed Web of Science ®Google Scholar
• Ayano G. Dopamine: receptors, functions, synthesis, pathways, locations and mental disorders: review of literatures. J Ment Disord Treat. 2016;2(120):2.
   Google Scholar
• Södersten P, Bergh C, Leon M, Zandian M. Dopamine and anorexia nervosa. Neurosci Biobehav Rev. 2016;60:26–30.
   PubMed Web of Science ®Google Scholar
• Bailer UF, Price JC, Meltzer CC, Wagner A, Mathis CA, Gamst A, Kaye WH. Dopaminergic activity and altered reward modulation in anorexia nervosa-insight from multimodal imaging. Int J Eating Disord. 2017;50(5):593–6.
   PubMed Web of Science ®Google Scholar
• Steinglass JE, Walsh BT. Neurobiological model of the persistence of anorexia nervosa. J Eat Disord. 2016;4(1):19.
   PubMedGoogle Scholar
• Wang HL, Zhang S, Qi J, Wang H, Cachope R, Mejias-Aponte CA, et al. Dorsal raphe dual serotonin-glutamate neurons drive reward by establishing excitatory synapses on VTA mesoaccumbens dopamine neurons. Cell Rep. 2019;26(5):1128–42.e7.
   PubMed Web of Science ®Google Scholar
• Niederkofler V, Asher TE, Dymecki SM. Functional interplay between dopaminergic and serotonergic neuronal systems during development and adulthood. ACS Chem Neurosci. 2015;6(7):1055–70.
   PubMed Web of Science ®Google Scholar
• Alex KD, Pehek EA. Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission. Pharmacol Ther. 2007;113(2):296–320.
   PubMed Web of Science ®Google Scholar
• Mehdi BJ, Haleem DJ. Long-term administration of rice bran oil attenuates 5-HT1A receptor dependent responses in rats. J Anim Res Nutr. 2018;3:1–6.
   Google Scholar
• Haleem DJ. 5-HT1A receptor-dependent control of nigrostriatal dopamine neurotransmission in the pharmacotherapy of Parkinson’s disease and schizophrenia. Behav Pharmacol. 2015;26(1 and 2-Special Issue):45–58.
   PubMed Web of Science ®Google Scholar
• Allaway HC, Southmayd EA, De Souza MJ. The physiology of functional hypothalamic amenorrhea associated with energy deficiency in exercising women and in women with anorexia nervosa. Horm Mol Biol Clin Investig. 2016;25(2):91–119.
   PubMed Web of Science ®Google Scholar
• Saleem DM, Mehboob S, Khan MM, Samad N, Zafar A, Haleem DJ. Inhibition of diet-restriction-induced behavioral deficits by tryptophan administration in rats. Pak J Pharm Sci. 2018;31:1021–9.
   PubMed Web of Science ®Google Scholar
• Ali O, Haleem DJ, Obaid R, Kamil N, Haleem MA, Ahmed SW. Effect of co administration of haloperidol and large neutral amino acids (tryptophan and valine) on rats striatal dopamine, serotonin and their metabolism. Pak J Pharm Sci. 2003;16(1):13–25.
   PubMedGoogle Scholar
• Salim A, Haleem R, Murtaza F, Shameem G, Perveen T, Haleem DJ. Injected tryptophan increases brain but not plasma tryptophan levels more in restrained rats. Pak J Pharm Sci. 2003;16(1):51–7.
   PubMedGoogle Scholar
• Cheema MAR, Nawaz S, Gul S, Salman T, Naqvi S, Dar A, Haleem DJ. Neurochemical and behavioral effects of nigella sativa and olea europaea oil in rats. Nutr Neurosci. 2018;21(3):185–94.
   PubMed Web of Science ®Google Scholar
• Haleem DJ, Mahmood K. Brain serotonin in high-fat diet-induced weight gain, anxiety and spatial memory in rats. Nutr Neurosci. 2019: 1–10.
   Web of Science ®Google Scholar
• Salman T, Nawaz S, Waraich RS, Haleem DJ. Repeated administration of methylphenidate produces reinforcement and downregulates 5-HT-1A receptor expression in the nucleus accumbens. Life Sci. 2019;218:139–46.
   PubMed Web of Science ®Google Scholar
• Milos G, Baur V, Schumacher S, Kuenzli C, Schnyder U, Mueller-Pfeiffer C, Martin-Soelch C. How fat will it make me? Estimation of weight gain in anorexia nervosa. Appetite. 2017;114:368–73.
   PubMed Web of Science ®Google Scholar
• Scherma M, Collu R, Satta V, Giunti E, Fadda P. Animal models of eating disorders. In: Kobeissy F. (eds) Psychiatric disorders. New York (NY): Humana; 2019. p. 297–314.
   Google Scholar
• Gauthier C, Hassler C, Mattar L, Launay JM, Callebert J, Steiger H, Lang F. Symptoms of depression and anxiety in anorexia nervosa: links with plasma tryptophan and serotonin metabolism. Psychoneuroendocrinology. 2014;39:170–8.
   PubMed Web of Science ®Google Scholar
• Aoki C, Chowdhury TG, Wable GS, Chen YW. Synaptic changes in the hippocampus of adolescent female rodents associated with resilience to anxiety and suppression of food restriction-evoked hyperactivity in an animal model for anorexia nervosa. Brain Res. 2017;1654:102–15.
   PubMed Web of Science ®Google Scholar
• Haleem DJ. Exaggerated feedback control decreases brain serotonin concentration and elicits hyperactivity in a rat model of diet-restriction-induced anorexia nervosa. Appetite. 2009;52(1):44–50.
   PubMed Web of Science ®Google Scholar
• Barbarich NC, Kaye WH, Jimerson D. Neurotransmitter and imaging studies in anorexia nervosa: new targets for treatment. Current Drug Targets-CNS & Neurological Disorders. 2003;2(1):61–72.
   PubMedGoogle Scholar
• Kaye WH, Barbarich NC, Putnam K, Gendall KA, Fernstrom J, Fernstrom M, et al. Anxiolytic effects of acute tryptophan depletion in anorexia nervosa. Int J Eating Disord. 2003;33(3):257–67.
   PubMed Web of Science ®Google Scholar
• Lloyd EC, Frampton I, Verplanken B, Haase AM. How extreme dieting becomes compulsive: a novel hypothesis for the role of anxiety in the development and maintenance of anorexia nervosa. Med Hypotheses. 2017;108:144–50.
   PubMed Web of Science ®Google Scholar
• Haider S, Khaliq S, Haleem DJ. Enhanced serotonergic neurotransmission in the hippocampus following tryptophan administration improves learning acquisition and memory consolidation in rats. Pharmacol Rep. 2007;59(1):53–57.
   PubMed Web of Science ®Google Scholar
• Frank GK, Shott ME, DeGuzman MC. Recent advances in understanding anorexia nervosa. F1000Res. 2019;8:1–7.
   Google Scholar
• Jankovic J. Parkinson’s disease tremors and serotonin. Brain. 2018;141(3):624–6.
   PubMedGoogle Scholar
• Sgambato-Faure V, Tremblay L. Dopamine and serotonin modulation of motor and non-motor functions of the non-human primate striato-pallidal circuits in normal and pathological states. J Neural Transm. 2018;125(3):485–500.
   PubMed Web of Science ®Google Scholar
• Haleem DJ. Extending therapeutic use of psychostimulants: focus on serotonin-1A receptor. Prog Neuro-Psychopharmacol Biol Psychiatry. 2013;46:170–80.
   PubMed Web of Science ®Google Scholar
• Savitz J, Lucki I, Drevets WC. 5-HT1A receptor function in major depressive disorder. Prog Neurobiol. 2009;88(1):17–31.
   PubMed Web of Science ®Google Scholar
• Albert PR, Le Francois B, Vahid-Ansari F. Genetic, epigenetic and posttranscriptional mechanisms for treatment of major depression: the 5-HT1A receptor gene as a paradigm. Journal of Psychiatry & Neuroscience: JPN. 2019;44(3):164–76.
   PubMed Web of Science ®Google Scholar
• Popova NK, Naumenko VS. 5-HT1A receptor as a key player in the brain 5-HT system. Rev Neurosci. 2013;24(2):191–204.
   PubMed Web of Science ®Google Scholar
• Haleem DJ, Gul S. Circulating leptin, cortisol and gender differences associated with anorexia or obesity in depression. World J Biol Psychiatry. 2020;21(3):195–202.
   PubMed Web of Science ®Google Scholar