Blueberry treatment administered before and/or after lipopolysaccharide stimulation attenuates inflammation and oxidative stress in rat microglial cells

References

• Lull ME, Block ML. Microglial activation and chronic neurodegeneration. Neurotherapeutics. 2010;7(4):354–65.
   PubMed Web of Science ®Google Scholar
• Dringen R. Oxidative and antioxidative potential of brain microglial cells. Antioxid Redox Signal. 2005;7(9-10):1223–33.
   PubMed Web of Science ®Google Scholar
• Lijia Z, Zhao S, Wang X, Wu C, Yang J. A self-propelling cycle mediated by reactive oxide species and nitric oxide exists in LPS-activated microglia. Neurochem Int. 2012;61(7):1220–30.
   PubMed Web of Science ®Google Scholar
• Qin L, Wu X, Block ML, Liu Y, Breese GR, Hong JS, et al. Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration. Glia. 2007;55(5):453–62.
   PubMed Web of Science ®Google Scholar
• Liu B, Gao HM, Hong JS. Parkinson's disease and exposure to infectious agents and pesticides and the occurrence of brain injuries: role of neuroinflammation. Environ Health Perspect. 2003;111(8):1065–73.
   PubMed Web of Science ®Google Scholar
• Parihar VK, Maroso M, Syage A, Allen BD, Angulo MC, Soltesz I, Limoli CL. Persistent nature of alterations in cognition and neuronal circuit excitability after exposure to simulated cosmic radiation in mice. Exp Neurol. 2018;305(2018):44–55.
   PubMedGoogle Scholar
• Debnath-Canning M, Unruh S, Vyas P, Daneshtalab N, Igamberdiev AU, Weber JT. Fruits and leaves from wild blueberry plants contain diverse polyphenols and decrease neuroinflammatory responses in microglia. J Funct Foods. 2020;68(2020):103906.
   Google Scholar
• Andres-Lacueva C, Shukitt-Hale B, Galli RL, Jauregui O, Lamuela-Raventos RM, Joseph JA. Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory. Nutr Neurosci. 2005;8(2):111–20.
   PubMed Web of Science ®Google Scholar
• Rabin BM, Shukitt-Hale B. A voyage to Mars: Space radiation, aging, and nutrition. Nutrition and Aging. 2014;2(4):233–241.
   Google Scholar
• Slemmer JE, Shacka JJ, Sweeney MI, Weber JT. Antioxidants and free radical scavengers for the treatment of stroke, traumatic brain injury and aging. Curr Med Chem. 2008;15(4):404–14.
   PubMed Web of Science ®Google Scholar
• Shukitt-Hale B, Lau FC, Carey AN, Galli RL, Spangler EL, Ingram DK, Joseph JA. Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus. Nutr Neurosci. 2008;11(4):172–82.
   PubMed Web of Science ®Google Scholar
• Lau FC, Bielinski DF, Joseph JA. Inhibitory effects of blueberry extract on the production of inflammatory mediators in lipopolysaccharide-activated BV2 microglia. J Neurosci Res. 2007;85(5):1010–7.
   PubMed Web of Science ®Google Scholar
• Carey AN, Fisher DR, Rimando AM, Gomes SM, Bielinski DF, Shukitt-Hale B. Stilbenes and anthocyanins reduce stress signaling in BV-2 mouse microglia. J Agric Food Chem. 2013;61(25):5979–86.
   PubMed Web of Science ®Google Scholar
• Zhu Y, Bickford PC, Sanberg P, Giunta B, Tan J. Blueberry opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activation protein kinase. Rejuvenation Res. 2008;11(5):891–901.
   PubMed Web of Science ®Google Scholar
• Bozic I, Savic D, Laketa D, Bjelobaba I, Milenkovic I, Pekovic S, et al. Benfotiamine attenuates inflammatory response in LPS stimulated BV-2 microglia. PLoS One. 2015;10(2):e0118372.
   PubMed Web of Science ®Google Scholar
• Zhou X, Gan P, Hao L, Tao L, Jia J, Gao B, et al. Antiinflammatory effects of orientin-2"-O-galactopyranoside on lipopolysaccharide-stimulated microglia. Biol Pharm Bull. 2014;37(8):1282–94.
   PubMed Web of Science ®Google Scholar
• Strober W. Trypan Blue Exclusion Test of Cell Viability. Curr Protoc Immunol. 2015;111(1):A3 B 1–A3 B 3.
   PubMedGoogle Scholar
• Poulose SM, Fisher DR, Larson J, Bielinski DF, Rimando AM, Carey AN, et al. Anthocyanin-rich acai (Euterpe oleracea Mart.) fruit pulp fractions attenuate inflammatory stress signaling in mouse brain BV-2 microglial cells. J Agric Food Chem. 2012;60(4):1084–93.
   PubMed Web of Science ®Google Scholar
• Lau FC, Joseph JA, McDonald JE, Kalt W. Attenuation of iNOS and COX2 by blueberry polyphenols is mediated through the suppression of NF-κB activation. J Functional Foods. 2009;1(3):274–283.
   Web of Science ®Google Scholar
• Serra D, Henriques JF, Serra T, Bento Silva A, Bronze MR, Dinis TC, etal An Anthocyanin-Rich Extract Obtained from Portuguese Blueberries Maintains Its Efficacy in Reducing Microglia-Driven Neuroinflammation after Simulated Digestion. Nutrients. 2020;12(12):3670.
   PubMed Web of Science ®Google Scholar
• Cheng A, Yan H, Han C, Wang W, Tian Y, Chen X. Polyphenols from blueberries modulate inflammation cytokines in LPS-induced RAW264.7 macrophages. Int J Biol Macromol. 2014;69(2014):382–7.
   PubMedGoogle Scholar
• Cheng A, Han C, Fang X, Sun J, Chen X, Wan F. Extractable and non-extractable polyphenols from blueberries modulate LPS-induced expression of iNOS and COX-2 in RAW264.7 macrophages via the NF-kappaB signalling pathway. J Sci Food Agric. 2016;96(10):3393–400.
   PubMed Web of Science ®Google Scholar
• Ebenezer PJ, Wilson CB, Wilson LD, Nair AR. The Anti-Inflammatory Effects of Blueberries in an Animal Model of Post-Traumatic Stress Disorder (PTSD). PLoS One. 2016;11(9):e0160923.
   PubMed Web of Science ®Google Scholar
• Wadsworth TL, McDonald TL, Koop DR. Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-alpha. Biochem Pharmacol. 2001;62(7):963–74.
   PubMed Web of Science ®Google Scholar
• Panaro MA, Carofiglio V, Acquafredda A, Cavallo P, Cianciulli A. Anti-inflammatory effects of resveratrol occur via inhibition of lipopolysaccharide-induced NF-kappaB activation in Caco-2 and SW480 human colon cancer cells. Br J Nutr. 2012;108(9):1623–32.
   PubMed Web of Science ®Google Scholar
• Elks CM, Reed SD, Mariappan N, Shukitt-Hale B, Joseph JA, Ingram DK, Francis J. A blueberry-enriched diet attenuates nephropathy in a rat model of hypertension via reduction in oxidative stress. PLoS One. 2011;6(9):e24028.
   PubMed Web of Science ®Google Scholar
• Murugaiyah V, Mattson MP. Neurohormetic phytochemicals: An evolutionary-bioenergetic perspective. Neurochem Int. 2015;89:271–80.
   PubMed Web of Science ®Google Scholar
• Wang J, Mazza G. Effects of anthocyanins and other phenolic compounds on the production of tumor necrosis factor alpha in LPS/IFN-gamma-activated RAW 264.7 macrophages. J Agric Food Chem. 2002;50(15):4183–9.
   PubMed Web of Science ®Google Scholar
• Shen M, Chan TH, Dou QP. Targeting tumor ubiquitin-proteasome pathway with polyphenols for chemosensitization. Anticancer Agents Med Chem. 2012;12(8):891–901.
   PubMed Web of Science ®Google Scholar
• Sun GY, Chen Z, Jasmer KJ, Chuang DY, Gu Z, Hannink M, Simonyi A. Quercetin Attenuates Inflammatory Responses in BV-2 Microglial Cells: Role of MAPKs on the Nrf2 Pathway and Induction of Heme Oxygenase-1. PLoS One. 2015;10(10):e0141509.
   PubMed Web of Science ®Google Scholar
• Goyarzu P, Malin DH, Lau FC, Taglialatela G, Moon WD, Jennings R, et al. Blueberry supplemented diet: Effects on object recognition memory and nuclear factor-kappa B levels in aged rats. Nutr Neurosci. 2004;7(2):75–83.
   PubMed Web of Science ®Google Scholar