Calorie restriction protects against acute systemic LPS-induced inflammation

References

• Furman D, Campisi J, Verdin E, Carrera-Bastos P, Targ S, Franceschi C, et al. Chronic inflammation in the etiology of disease across the life span. Nat Med. 2019;25(12):1822–32. doi:10.1038/s41591-019-0675-0.
   PubMed Web of Science ®Google Scholar
• Stromsnes K, Correas AG, Lehmann J, Gambini J, Olaso-Gonzalez G. Anti-inflammatory properties of diet: role in healthy aging. Biomedicines. 2021;9(8):922. doi:10.3390/biomedicines9080922.
   PubMed Web of Science ®Google Scholar
• Bok E, Jo M, Lee S, Lee B-R, Kim J, Kim H-J. Dietary restriction and neuroinflammation: a potential mechanistic link. Int J Mol Sci. 2019;20(3):464. doi:10.3390/ijms20030464.
   PubMed Web of Science ®Google Scholar
• Madeo F, Carmona-Gutierrez D, Hofer SJ, Kroemer G. Caloric restriction mimetics against age-associated disease: targets, mechanisms, and therapeutic potential. Cell Metab. 2019;29(3):592–610. doi:10.1016/j.cmet.2019.01.018.
   PubMed Web of Science ®Google Scholar
• Popov A, Denisov P, Bychkov M, Brazhe A, Lyukmanova E, Shenkarev Z, et al. Caloric restriction triggers morphofunctional remodeling of astrocytes and enhances synaptic plasticity in the mouse hippocampus. Cell Death Dis. 2020;11(3):208. doi:10.1038/s41419-020-2406-3.
   PubMed Web of Science ®Google Scholar
• Gensous N, Franceschi C, Santoro A, Milazzo M, Garagnani P, Bacalini MG. The impact of caloric restriction on the epigenetic signatures of aging. Int J Mol Sci. 2019;20(8):2022. doi:10.3390/ijms20082022.
   PubMed Web of Science ®Google Scholar
• Pifferi F, Aujard F. Caloric restriction, longevity and aging: recent contributions from human and non-human primate studies. Prog Neuro-Psychopharmacol Biol Psychiatry. 2019;95:109702. doi:10.1016/j.pnpbp.2019.109702.
   PubMed Web of Science ®Google Scholar
• Amigo I, Menezes-Filho SL, Luévano-Martínez LA, Chausse B, Kowaltowski AJ. Caloric restriction increases brain mitochondrial calcium retention capacity and protects against excitotoxicity. Aging Cell. 2017;16(1):73–81. doi:10.1111/acel.12527.
   PubMed Web of Science ®Google Scholar
• Redman LM, Smith SR, Burton JH, Martin CK, Il’yasova D, Ravussin E. Metabolic slowing and reduced oxidative damage with sustained caloric restriction support the rate of living and oxidative damage theories of aging. Cell Metab. 2018;27(4):805–15.e4. doi:10.1016/j.cmet.2018.02.019.
   PubMed Web of Science ®Google Scholar
• Smith RL, Soeters MR, Wüst RCI, Houtkooper RH. Metabolic flexibility as an adaptation to energy resources and requirements in health and disease. Endocr Rev. 2018;39(4):489–517. doi:10.1210/er.2017-00211.
   PubMed Web of Science ®Google Scholar
• Wahl D, Solon-Biet SM, Wang Q-P, Wali JA, Pulpitel T, Clark X, et al. Comparing the effects of Low-protein and high-carbohydrate diets and caloric restriction on brain aging in mice. Cell Rep. 2018;25(8):2234–43.e6. doi:10.1016/j.celrep.2018.10.070.
   PubMed Web of Science ®Google Scholar
• Bettio LEB, Rajendran L, Gil-Mohapel J. The effects of aging in the hippocampus and cognitive decline. Neurosci Biobehav Rev. 2017;79:66–86. doi:10.1016/j.neubiorev.2017.04.030.
   PubMed Web of Science ®Google Scholar
• Newcombe EA, Camats-Perna J, Silva ML, Valmas N, Huat TJ, Medeiros R. Inflammation: the link between comorbidities, genetics, and Alzheimer’s disease. J Neuroinflammation. 2018;15(1):276. doi:10.1186/s12974-018-1313-3.
   PubMed Web of Science ®Google Scholar
• Wahl D, Cogger VC, Solon-Biet SM, Waern RVR, Gokarn R, Pulpitel T, et al. Nutritional strategies to optimise cognitive function in the aging brain. Ageing Res Rev. 2016;31:80–92. doi:10.1016/j.arr.2016.06.006.
   PubMed Web of Science ®Google Scholar
• Gonçalves C-A, Rodrigues L, Bobermin LD, Zanotto C, Vizuete A, Quincozes-Santos A, et al. Glycolysis-derived compounds from astrocytes that modulate synaptic communication. Front Neurosci. 2019;12:1035. doi:10.3389/fnins.2018.01035.
   PubMed Web of Science ®Google Scholar
• dos Santos JPA, Vizuete AF, Gonçalves C-A. Calcineurin-mediated hippocampal inflammatory alterations in streptozotocin-induced model of dementia. Mol Neurobiol. 2020;57(1):502–12. doi:10.1007/s12035-019-01718-2.
   PubMed Web of Science ®Google Scholar
• Harrison L, Pfuhlmann K, Schriever SC, Pfluger PT. Profound weight loss induces reactive astrogliosis in the arcuate nucleus of obese mice. Mol Metab. 2019;24:149–55. doi:10.1016/j.molmet.2019.03.009.
   PubMed Web of Science ®Google Scholar
• Norden DM, Trojanowski PJ, Villanueva E, Navarro E, Godbout JP. Sequential activation of microglia and astrocyte cytokine expression precedes increased iba-1 or GFAP immunoreactivity following systemic immune challenge: Iba1 and GFAP are unreliable activation markers. Glia. 2016;64(2):300–16. doi:10.1002/glia.22930.
   PubMed Web of Science ®Google Scholar
• Escartin C, Galea E, Lakatos A, O’Callaghan JP, Petzold GC, Serrano-Pozo A, et al. Reactive astrocyte nomenclature, definitions, and future directions. Nat Neurosci. 2021;24(3):312–25. doi:10.1038/s41593-020-00783-4.
   PubMed Web of Science ®Google Scholar
• Dringen R, Brandmann M, Hohnholt MC, Blumrich E-M. Glutathione-dependent detoxification processes in astrocytes. Neurochem Res. 2015;40(12):2570–82. doi:10.1007/s11064-014-1481-1.
   PubMed Web of Science ®Google Scholar
• Kupferschmid BJ, Therrien B, Rowsey PJ. Different sickness responses in adult and aged rats following lipopolysaccharide administration. Biol Res Nurs. 2018;20(3):335–42. doi:10.1177/1099800418759599.
   PubMed Web of Science ®Google Scholar
• Bobermin LD, Weber FB, dos Santos TM, Belló-Klein A, Wyse ATS, Gonçalves C-A, Quincozes-Santos A. Sulforaphane induces glioprotection after LPS challenge. Cell Mol Neurobiol. 2022;42(3):829–46. doi:10.1007/s10571-020-00981-5.
   PubMed Web of Science ®Google Scholar
• Kwon HS, Koh S-H. Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes. Transl Neurodegener. 2020;9(1):42. doi:10.1186/s40035-020-00221-2.
   PubMed Web of Science ®Google Scholar
• de Oliveira TQ, de Moura AC, Feistauer V, Damiani R, Braga MF, Almeida S, et al. Caloric restriction in mice improves short-term recognition memory and modifies the neuroinflammatory response in the hippocampus of male adult offspring. Behav Brain Res. 2022;425:113838. doi:10.1016/j.bbr.2022.113838.
   PubMed Web of Science ®Google Scholar
• Burfeind KG, Michaelis KA, Marks DL. The central role of hypothalamic inflammation in the acute illness response and cachexia. Semin Cell Dev Biol. 2016;54:42–52. doi:10.1016/j.semcdb.2015.10.038.
   PubMed Web of Science ®Google Scholar
• DiSabato DJ, Quan N, Godbout JP. Neuroinflammation: the devil is in the details. J Neurochem. 2016;139:136–53. doi:10.1111/jnc.13607.
   PubMed Web of Science ®Google Scholar
• Zolfaghari SI, Rabbani Khorasgani M, Noorbakhshnia M. The effects of lactobacilli (L. rhamnosus, L. reuteri, L. plantarum) on LPS-induced memory impairment and changes in CaMKII-α and TNF-α genes expression in the hippocampus of rat. Physiol Behav. 2021;229:113224. doi:10.1016/j.physbeh.2020.113224.
   PubMed Web of Science ®Google Scholar
• Ribeiro LC, Quincozes-Santos A, Leite MC, Abib RT, Kleinkauf-Rocha J, Biasibetti R, et al. Caloric restriction increases hippocampal glutamate uptake and glutamine synthetase activity in Wistar rats. Neurosci Res. 2009;64(3):330–4. doi:10.1016/j.neures.2009.04.004.
   PubMed Web of Science ®Google Scholar
• Andrade VS, Rojas DB, de Andrade RB, Kim TDH, Vizuete AF, Zanatta Â, et al. A possible anti-inflammatory effect of proline in the brain cortex and cerebellum of rats. Mol Neurobiol [Internet]. 2017;55:4068–4077. [accessed 2023 Apr 9]. doi:10.1007/s12035-017-0626-z.
   PubMed Web of Science ®Google Scholar
• Ribeiro LC, Rodrigues L, Quincozes-Santos A, Tramontina AC, Bambini-Junior V, Zanotto C, et al. Caloric restriction improves basal redox parameters in hippocampus and cerebral cortex of Wistar rats. Brain Res. 2012;1472:11–9. doi:10.1016/j.brainres.2012.07.021.
   PubMed Web of Science ®Google Scholar
• Browne RW, Armstrong D. Reduced glutathione and glutathione disulfide. In: Armstrong D, editor. Free radical and antioxidant protocols [internet]. Vol. 108. New Jersey: Humana Press; 1998. p. 347–52. [accessed 2021 Aug 16]. doi:10.1385/0-89603-472-0:347. 
   Google Scholar
• Lissner LJ, Rodrigues L, Wartchow KM, Borba E, Bobermin LD, Fontella FU, et al. Short-term alterations in behavior and astroglial function after intracerebroventricular infusion of methylglyoxal in rats. Neurochem Res. 2021;46(2):183–96. doi:10.1007/s11064-020-03154-4.
   PubMed Web of Science ®Google Scholar
• Da Ré C, Souza JM, Fróes F, Taday J, dos Santos JP, Rodrigues L, et al. Neuroinflammation induced by lipopolysaccharide leads to memory impairment and alterations in hippocampal leptin signaling. Behav Brain Res. 2020;379:112360. doi:10.1016/j.bbr.2019.112360.
   PubMed Web of Science ®Google Scholar
• Wartchow KM, Rodrigues L, Lissner LJ, Federhen BC, Selistre NG, Moreira A, et al. Insulin-producing cells from mesenchymal stromal cells: protection against cognitive impairment in diabetic rats depends upon implant site. Life Sci. 2020;251:117587. doi:10.1016/j.lfs.2020.117587.
   PubMed Web of Science ®Google Scholar
• Peterson GL. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal Biochem. 1977;83(2):346–56. doi:10.1016/0003-2697(77)90043-4.
   PubMed Web of Science ®Google Scholar
• Santin K, da Rocha RF, Cechetti F, Quincozes-Santos A, de Souza DF, Nardin P, et al. Moderate exercise training and chronic caloric restriction modulate redox status in rat hippocampus. Brain Res. 2011;1421:1–10. doi:10.1016/j.brainres.2011.08.003.
   PubMed Web of Science ®Google Scholar
• Corrales P, Vidal-Puig A, Medina-Gómez G. Ppars and metabolic disorders associated with challenged adipose tissue plasticity. Int J Mol Sci. 2018;19(7):2124. doi:10.3390/ijms19072124.
   PubMed Web of Science ®Google Scholar
• Sun C, Mao S, Chen S, Zhang W, Liu C. PPARs-Orchestrated metabolic homeostasis in the adipose tissue. Int J Mol Sci. 2021;22(16):8974. doi:10.3390/ijms22168974.
   PubMed Web of Science ®Google Scholar
• Jaitovich MM, Varela A, Sbarbati C, Hermann R, Torresín ME, Savino EA, Marina Prendes MG. Restricted feeding improves postischemic recovery of Langendorff-perfused rat hearts. Can J Physiol Pharmacol. 2010;88(10):1002–9. doi:10.1139/Y10-076.
   PubMed Web of Science ®Google Scholar
• Rebrin I, Kamzalov S, Sohal RS. Effects of age and caloric restriction on glutathione redox state in mice. Free Radical Biol Med. 2003;35(6):626–35. doi:10.1016/S0891-5849(03)00388-5.
   PubMed Web of Science ®Google Scholar
• Mantovani A, Garlanda C. Humoral innate immunity and acute-phase Proteins. Longo DL, editor. N Engl J Med. 2023;388(5):439–52. doi:10.1056/NEJMra2206346.
   PubMed Web of Science ®Google Scholar
• Sander LE, Sackett SD, Dierssen U, Beraza N, Linke RP, Müller M, et al. Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function. J Exp Med. 2010;207(7):1453–64. doi:10.1084/jem.20091474.
   PubMed Web of Science ®Google Scholar
• Tweedell A, Mulligan KX, Martel JE, Chueh F-Y, Santomango T, McGuinness OP. Metabolic response to endotoxin in vivo in the conscious mouse: role of interleukin-6. Metabolism. 2011;60(1):92–8. doi:10.1016/j.metabol.2009.12.022.
   PubMed Web of Science ®Google Scholar
• Xu C, Feng C, Huang P, Li Y, Liu R, Liu C, et al. TNFα and IFNγ rapidly activate PI3K-AKT signaling to drive glycolysis that confers mesenchymal stem cells enhanced anti-inflammatory property. Stem Cell Res Ther. 2022;13(1):491. doi:10.1186/s13287-022-03178-3.
   PubMed Web of Science ®Google Scholar
• Kraus WE, Bhapkar M, Huffman KM, Pieper CF, Krupa Das S, Redman LM, et al. 2 years of calorie restriction and cardiometabolic risk (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial. Lancet Diabetes Endocrinol. 2019;7(9):673–83. doi:10.1016/S2213-8587(19)30151-2.
   PubMed Web of Science ®Google Scholar
• Montefusco L, D’Addio F, Loretelli C, Ben Nasr M, Garziano M, Rossi A, et al. Anti-inflammatory effects of diet and caloric restriction in metabolic syndrome. J Endocrinol Invest. 2021;44(11):2407–15. doi:10.1007/s40618-021-01547-y.
   PubMed Web of Science ®Google Scholar
• Hansen SB, Wang H. The shared role of cholesterol in neuronal and peripheral inflammation. Pharmacol Ther. 2023;249:108486. doi:10.1016/j.pharmthera.2023.108486.
   PubMed Web of Science ®Google Scholar
• Perovic M, Mladenovic Djordjevic A, Smiljanic K, Tanic N, Rakic L, Ruzdijic S, Kanazir S. Expression of cholesterol homeostasis genes in the brain of the male rat is affected by age and dietary restriction. Biogerontology. 2009;10(6):735–45. doi:10.1007/s10522-009-9220-8.
   PubMed Web of Science ®Google Scholar
• Slotnick SD. The hippocampus and long-term memory. Cogn Neurosci. 2022;13(3-4):113–4. doi:10.1080/17588928.2022.2128736.
   PubMed Web of Science ®Google Scholar
• Yoo S, Blackshaw S. Regulation and function of neurogenesis in the adult mammalian hypothalamus. Prog Neurobiol. 2018;170:53–66. doi:10.1016/j.pneurobio.2018.04.001.
   PubMed Web of Science ®Google Scholar
• Tuomi K, Logomarsino JV. Bacterial lipopolysaccharide, lipopolysaccharide-binding protein, and other inflammatory markers in obesity and after bariatric surgery. Metab Syndr Relat Disord. 2016;14(6):279–88. doi:10.1089/met.2015.0170.
   PubMed Web of Science ®Google Scholar
• Radler ME, Hale MW, Kent S. Calorie restriction attenuates lipopolysaccharide (LPS)-induced microglial activation in discrete regions of the hypothalamus and the subfornical organ. Brain Behav Immun. 2014;38:13–24. doi:10.1016/j.bbi.2013.11.014.
   PubMed Web of Science ®Google Scholar
• Radler ME, Wright BJ, Walker FR, Hale MW, Kent S. Calorie restriction increases lipopolysaccharide-induced neuropeptide Y immunolabeling and reduces microglial cell area in the arcuate hypothalamic nucleus. Neuroscience. 2015;285:236–47. doi:10.1016/j.neuroscience.2014.11.014.
   PubMed Web of Science ®Google Scholar
• McDonald JR, Finck BK, McIntosh LM, Wilson SE. Anti-inflammatory approaches that target the chemokine network. Recent Pat Inflammation Allergy Drug Discovery. 2011;5(1):1–16. doi:10.2174/187221311794474829.
   PubMedGoogle Scholar
• Verkhratsky A, Augusto-Oliveira M, Pivoriūnas A, Popov A, Brazhe A, Semyanov A. Astroglial asthenia and loss of function, rather than reactivity, contribute to the ageing of the brain. Pflugers Arch Eur J Physiol. 2021;473(5):753–74. doi:10.1007/s00424-020-02465-3.
   PubMed Web of Science ®Google Scholar