Publication Cover
Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Latest Articles
70
Views
0
CrossRef citations to date
0
Altmetric
Research Article

Ketogenic diet therapies as a non-pharmacological adjuvant in resistant epilepsy: retrospective analysis of adult outpatients in Colombia

, , &

References

  • World Health Organization. Epilepsy. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/epilepsy. (2023).
  • Pan American Health Organization. Epilepsy. PAHO. https://www.paho.org/en/topics/epilepsy. (2023).
  • Alva-Díaz C, Navarro-Flores A, Rivera-Torrejon O, Huerta-Rosario A, Molina RA, Velásquez-Rimachi V, et al. Prevalence and incidence of epilepsy in Latin America and the Caribbean: a systematic review and meta-analysis of population-based studies. Epilepsia. 2021;62:984–96. doi:10.1111/epi.16850
  • Vos T, Lim SS, Abbafati C, Abbas KM, Abbasi M, Abbasifard M, et al. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396:1204–22. doi:10.1016/S0140-6736(20)30925-9
  • Rodriguez-Acevedo AJ, Gordon LG, Waddell N, Hollway G, Vadlamudi L. Developing a gene panel for pharmacoresistant epilepsy: a review of epilepsy pharmacogenetics. Pharmacogenomics. 2021;22:225–34. doi:10.2217/pgs-2020-0145
  • Strzelczyk A, Reese JP, Dodel R, Hamer HM. Cost of epilepsy: a systematic review. PharmacoEconomics. 2008;26:463–76. doi:10.2165/00019053-200826060-00002
  • Sondhi V, Sharma S. Non-pharmacological and non-surgical treatment of refractory childhood epilepsy. Indian J Pediatr. 2020;87:1062–9. doi:10.1007/s12098-019-03164-3
  • Rm W. The effects of ketonemia on the course of epilepsy. InMayo Clin Proc. 1921;2:307–8.
  • Goswami JN, Sharma S. Current perspectives on the role of the ketogenic diet in epilepsy management. Neuropsychiatr Dis Treat. 2019;15:3273–85. doi:10.2147/NDT.S201862
  • Barzegar M, Rahimi Khamaneh S, Raeisi S. Ketogenic diet: overview, types, and possible anti-seizure mechanisms. Nutr Neurosci. 2019;0:1–10.
  • Augustin K, Khabbush A, Williams S, Eaton S, Orford M, Cross JH, etal Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders. Lancet Neurol. 2018;17:84–93. doi:10.1016/S1474-4422(17)30408-8
  • Wells J, Swaminathan A, Paseka J, Hanson C. Efficacy and safety of a ketogenic diet in children and adolescents with refractory epilepsy—a review. Nutrients. 2020;12:1–19. doi:10.3390/nu12061809
  • Cervenka MC, Wood S, Bagary M, Balabanov A, Bercovici E, Brown M-G, etal International recommendations for the management of adults treated with ketogenic diet therapies. Neurol Clin Pract. 2021;11:385–97. doi:10.1212/CPJ.0000000000001007
  • Ruan Y, Chen L, She D, Chung Y, Ge L, Han L. Ketogenic diet for epilepsy: an overview of systematic review and meta-analysis. Eur J Clin Nutr. 2022;76:1234–44. doi:10.1038/s41430-021-01060-8
  • Bernal JC, Micolta PM, Torres LHC, Zúñiga-Núñez MA, Osorio JV. Efectos de la dieta cetogénica en pacientes adultos con epilepsia refractaria. Neurología Argentina. 2021;13:221–7. doi:10.1016/j.neuarg.2021.07.005
  • Kossoff EH, McGrogan JR, Bluml RM, Pillas DJ, Rubenstein JE, Vining EP. A modified atkins diet is effective for the treatment of intractable pediatric epilepsy. Epilepsia. 2006;47:421–4. doi:10.1111/j.1528-1167.2006.00438.x
  • Janmohamed M, Brodie MJ, Kwan P. Pharmacoresistance – epidemiology, mechanisms, and impact on epilepsy treatment. Neuropharmacology. 2020;168:107790. doi:10.1016/j.neuropharm.2019.107790
  • Williams TJ, Cervenka MC. The role for ketogenic diets in epilepsy and status epilepticus in adults. Clin Neurophysiol Pract. 2017;2:154–60. doi:10.1016/j.cnp.2017.06.001
  • Smith M, Politzer N, MacGarvie D, McAndrews MP, Del Campo M. Efficacy and tolerability of the modified atkins diet in adults with pharmacoresistant epilepsy: A prospective observational study. Epilepsia. 2011;52:775–80. doi:10.1111/j.1528-1167.2010.02941.x
  • Kossoff EH, Rowley H, Sinha SR, Vining EPG. A prospective study of the modified atkins diet for intractable epilepsy in adults. Epilepsia. 2008;49:316–9. doi:10.1111/j.1528-1167.2007.01256.x
  • Jagadish S, Payne ET, Wong-Kisiel L, Nickels KC, Eckert S, Wirrell EC. The ketogenic and modified atkins diet therapy for children with refractory epilepsy of genetic etiology. Pediatr Neurol. 2019;94:32–7. doi:10.1016/j.pediatrneurol.2018.12.012
  • Asadi-pooya AA. Lennox-Gastaut syndrome : a comprehensive review, p. 403–414 (2018)..
  • Armeno M, Araujo C, Sotomontesano B, Caraballo RH. Actualización sobre los efectos adversos durante la terapia con dieta cetogénica en la epilepsia refractaria pediátrica. Rev Neurol. 2018;66:193. doi:10.33588/rn.6606.2017280
  • Schoeler NE, Wood S, Aldridge V, Sander JW, Cross JH, Sisodiya SM. Ketogenic dietary therapies for adults with epilepsy: feasibility and classification of response. Epilepsy Behav. 2014;37:77–81. doi:10.1016/j.yebeh.2014.06.007
  • Kossoff EH, Al-Macki N, Cervenka MC, Kim HD, Liao J, Megaw K, et al. What are the minimum requirements for ketogenic diet services in resource-limited regions? Recommendations from the international league against epilepsy task force for dietary therapy. Epilepsia. 2015;56:1337–42. doi:10.1111/epi.13039
  • Pan American Health Organization. The management of epilepsy in the public health sector. Washington, D.C.: Pan American Health Organization; 2018.
  • Nkole KL, Kawatu N, Patel AA, Kanyinji C, Njobvu T, Chipeta J, Musuku J, et al. Ketogenic diet in Zambia: managing drug-resistant epilepsy in a low and middle income country. Epilepsy Behav Reports. 2020;14:100380. doi:10.1016/j.ebr.2020.100380

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.