References
- Aliro, Emilie, Annette C. Kuesel, Maria Magdalena Guraiib, Vânia de la Fuente-Núñez, Abha Saxena, and Melba F. Gomes. 2017. “Ethics Review of Studies During Public Health Emergencies—the Experience of the WHO Ethics Review Committee During the Ebola Virus Disease Epidemic.” BMC Medical Ethics 18 (43). https://bmcmedethics.biomedcentral.com/articles/10.1186/s12910-017-0201-1.
- Bambery, Ben, Michael Selgelid, Charles Weijer, Julian Savulescu, and Andrew J. Pollard. 2016. “Ethical Criteria for Human Challenge Studies in Infectious Diseases.” Public Health Ethics 9 (1): 92–103. doi: 10.1093/phe/phv026
- Baumgaertner, Emily. 2018. “Panel Calls for Review of Zika Virus Testing.” New York Times, April 24, D3.
- BIO. 2016. Clinical Development Success Rates 2006–2015. Biotechnology Innovation Organization. https://www.bio.org/press-release/bio-releases-largest-study-ever-clinical-development-success-rates.
- Boddie, Crystal. 2015. “Federal Funding in Support of Ebola Medical Countermeasures R&D.” Health Security 13 (1): 3–8. doi: 10.1089/hs.2015.0001
- Buzan, Barry, Ole Wæver, and Jaap de Wilde. 1998. Security: A New Framework for Analysis. Boulder: Lynne Rienner.
- Caplan, Arthur L. 2015. “Morality in a Time of Ebola.” The Lancet 385: e16–e17. doi: 10.1016/S0140-6736(14)61653-6
- CEPI. 2018a. Mission. Coalition for Epidemic Preparedness Innovations. Accessed 20 March. http://cepi.net/mission.
- CEPI. 2018b. Approach. Coalition for Epidemic Preparedness Innovations. Accessed 20 March. http://cepi.net/approach.
- Cohen, Jon. 2014. “Ebola Vaccine: Little and Late.” Science 345 (6203): 1441–1442. doi: 10.1126/science.345.6203.1441
- Cohen, Jon. 2016. “The Truest Test.” Science 352 (6288): 882–885. doi: 10.1126/science.352.6288.882
- Cohen, Jon. 2017. “A Half-billion-dollar Bid to Head off Emerging Diseases.” Science 355 (6322): 237. doi: 10.1126/science.355.6322.237
- Cox, Simon. 2014. “Ebola Crisis: Vaccine ‘Too Late’ for Outbreak.” BBC News, October 17, http://www.bbc.co.uk/news/health-29649572.
- Craig, Anne L., and Sukumar P. Desai. 2015. “‘Human Medical Experimentation with Extreme Prejudice: Lessons from the Doctors’ Trial at Nuremberg’.” Journal of Anesthesia History 1: 64–69. doi: 10.1016/j.janh.2015.06.001
- Davies, Sara E. 2008. “Securitizing Infectious Disease.” International Affairs 84 (2): 295–313. doi: 10.1111/j.1468-2346.2008.00704.x
- Dawson, Angus J. 2015. “Ebola: What It Tells Us About Medical Ethics.” Journal of Medical Ethics 41: 107–110. doi: 10.1136/medethics-2014-102304
- Dawson, Angus, and Marcel Verweij. 2012. “Solidarity: A Moral Concept in Need of Clarification.” Public Health Ethics 5 (1): 1–5. doi: 10.1093/phe/phs007
- Eckholm, Erik. 2003. “SARS is the Spark for a Riot in China.” New York Times, April 29, A1.
- Editorial. 2018. “Learning the Lessons of the Failed BCG Booster.” British Medical Journal 360 (8136): 52.
- Elbe, Stefan. 2006. “Should HIV/AIDS be Securitized? The Ethical Dilemmas of Linking HIV/AIDS and Security.” International Studies Quarterly 50 (1): 119–144. doi: 10.1111/j.1468-2478.2006.00395.x
- Elbe, Stefan, Anne Roemer-Mahler, and Christopher Long. 2014. “Securing Circulation Pharmaceutically: Antiviral Stockpiling and Pandemic Preparedness in the European Union.” Security Dialogue 45 (5): 440–457. doi: 10.1177/0967010614530072
- Emanuel, Ezekiel J., David Wendler, Jack Killen, and Christine Grady. 2004. “What Makes Clinical Research in Developing Countries Ethical? The Benchmarks of Ethical Research.” Journal of Infectious Diseases 189: 930–937. doi: 10.1086/381709
- Enserink, Martin. 2014a. “Ebola Drugs Still Stuck in Lab.” Science 345 (6195): 364–365. doi: 10.1126/science.345.6195.364
- Enserink, Martin. 2014b. “‘Debate Erupts on ‘Repurposed’ Drugs for Ebola.” Science 345 (6198): 718–719. doi: 10.1126/science.345.6198.718
- Farrar, Jeremy, David Heymann, and Peter Piot. 2014. Experimental Medicine in a Time of Ebola, Wellcome Trust. August 6. https://wellcome.ac.uk/news/experimental-medicine-time-ebola.
- FDA. 2018. Step 3: Clinical Research. US Food and Drug Administration. https://www.fda.gov/ForPatients/Approvals/Drugs/ucm405622.htm.
- Feasey, Nicholas A., and Myron M. Levine. 2017. “Typhoid Vaccine Development with a Human Challenge Model.” The Lancet 390: 2419–2421. doi: 10.1016/S0140-6736(17)32407-8
- Hackenbroch, Veronika, Markus Grill, and Katrin Elger. 2014. “The Global Hunt for an Ebola Vaccine.” Spiegel Online, November 28. http://www.spiegel.de/international/world/ebola-vaccine-search-moves-ahead-rapidly-a-1005602.html.
- Hayden, Erika Check. 2014. “Ethical Dilemma for Ebola Trials.” Nature 515: 177–178. doi: 10.1038/515177a
- Henao-Restrepo, Ana Maria, Anton Camacho, Ira M. Longini, Conall H. Watson, W. John Edmunds, Matthias Egger, Miles W. Carroll, et al. 2017. “Efficacy and Effectiveness of an rVSV-Vectored Vaccine in Preventing Ebola Virus Disease: Final Results from the Guinea Ring Vaccination, Open-Label, Cluster-Randomised Trial (Ebola Ça Suffit!).” The Lancet 389 (10068): 505–518. doi: 10.1016/S0140-6736(16)32621-6
- Holt, Kate. 2016. “Ebola Vaccine Trial in Sierra Leone Battles Against Fear and Logistics.” The Guardian, March 10. https://www.theguardian.com/global-development/2016/mar/10/ebola-vaccine-trial-sierra-leone-fear-logistics-immunisations.
- Hoyt, Kendall, and Richard Hatchett. 2016. “Preparing for the Next Zika.” Nature Biotechnology 34 (4): 384–386. doi: 10.1038/nbt.3532
- Jack, Andrew. 2008. “New Lease on Life? The Ethics of Offshoring Clinical Trials.” Financial Times, January 28. https://www.ft.com/content/6c77bb92-cdc7-11dc-9e4e-000077b07658.
- Jennings, Bruce, and Angus Dawson. 2015. “Solidarity in the Moral Imagination of Bioethics.” Hastings Center Report 45 (5): 31–38. doi: 10.1002/hast.490
- Keusch, Gerald, Keith McAdam, Patricia A. Cuff, Michelle Mancher, and Emily R. Busta. 2017. Integrating Clinical Research Into Epidemic Response: The Ebola Experience. Washington, DC: National Academies Press.
- Kupferschmidt, Kai. 2018. “Worms Living in Your Veins? Seventeen Volunteers Said ‘OK’.” Science 359 (6378): 853–854. doi: 10.1126/science.359.6378.853
- London, Leslie, Ashraf Kagee, Keymanthri Moodley, and Leslie Swartz. 2012. “Ethics, Human Rights and HIV Vaccine Trials in Low-income Settings.” Journal of Medical Ethics 38: 286–293. doi: 10.1136/medethics-2011-100227
- Marinissen, Maria Julia, Lauren Barna, Margaret Meyers, and Susan E. Sherman. 2014. “Strengthening Global Health Security by Developing Capacities to Deploy Medical Countermeasures Internationally.” Biosecurity and Bioterrorism 12 (5): 284–291. doi: 10.1089/bsp.2014.0049
- Maurice, John. 2014. “WHO Meeting Chooses Untried Interventions to Defeat Ebola.” The Lancet 384: e45–e46. doi: 10.1016/S0140-6736(14)61411-2
- McInnes, Colin, and Kelley Lee. 2006. “Health, Security and Foreign Policy.” Review of International Studies 32 (1): 5–23. doi: 10.1017/S0260210506006905
- McNeil, Donald G. 2017. “Curiosity, and Cash, Fight a Fever.” New York Times, October 3, D3.
- National Library of Medicine. 2017. Learn About Clinical Studies. US National Library of Medicine. https://clinicaltrials.gov/ct2/about-studies/learn.
- NIH. 2017. Ethics in Clinical Research. National Institutes of Health, US Department of Health and Human Services. https://www.cc.nih.gov/recruit/ethics.html.
- Nordling, Linda. 2018. “‘EU Crackdown on ‘Ethics Dumping’.” Nature 559: 17–18. doi: 10.1038/d41586-018-05616-w
- Nuremberg Code. 1949. “Permissible Medical Experiments.” In Trials of War Criminals Before the Nuremberg Military Tribunals under Control Council Law 10, Nuremberg, October 1946 to April 1949, Vol. 2, 181–182. Washington, DC: US Government Printing Office.
- Onishi, Norimitsu. 2014. “As Ebola Grips City, Quarantine Adds to Chaos.” New York Times, August 29, A1.
- Onishi, Norimitsu, and Sheri Fink. 2015. “Vaccines Face Same Mistrust That Fed Ebola.” New York Times, March 14, A1.
- Pittman, Phillip R. 2005. “An Assessment of Health Status among Medical Research Volunteers Who Served in the Project Whitecoat Program at Fort Detrick, Maryland.” Military Medicine 170 (3): 183–187. doi: 10.7205/MILMED.170.3.183
- Plotkin, Stanley A., Adel A. F. Mahmoud, and Jeremy Farrar. 2015. “Establishing a Global Vaccine-Development Fund.” New England Journal of Medicine 373 (4): 297–300. doi: 10.1056/NEJMp1506820
- Rid, Annette, and Ezekiel J. Emanuel. 2014. “Ethical Considerations of Experimental Interventions in the Ebola Outbreak.” The Lancet 384: 1896–1899. doi: 10.1016/S0140-6736(14)61315-5
- Roemer-Mahler, Anne, and Stefan Elbe. 2016. “The Race for Ebola Drugs: Pharmaceuticals, Security and Global Health Governance.” Third World Quarterly 37 (3): 487–506. doi: 10.1080/01436597.2015.1111136
- Rushton, Simon. 2011. “Global Health Security: Security for Whom? Security from What?” Political Studies 59 (4): 779–796. doi: 10.1111/j.1467-9248.2011.00919.x
- Savulescu, Julian. 2015. “Science Wars—How Much Risk Should Soldiers be Exposed to in Military Experimentation?” Journal of Law and the Biosciences 2 (1): 99–104. doi: 10.1093/jlb/lsv006
- Selgelid, Michael J., and Christian Enemark. 2008. “Infectious Diseases, Security and Ethics: The Case of HIV/AIDS.” Bioethics 22 (9): 457–465. doi: 10.1111/j.1467-8519.2008.00696.x
- Shuchman, Miriam. 2015. “Ebola Vaccine Trial in West Africa Faces Criticism.” The Lancet 385: 1933–1934. doi: 10.1016/S0140-6736(15)60938-2
- Stephenson, Jeffrey E., and Arthur O. Anderson. 2007. “Ethical and Legal Dilemmas in Biodefense Research.” In Medical Aspects of Biological Warfare, edited by Zygmunt F. Dembek, 559–577. Falls Church, VA/Washington, DC: Office of the Surgeon General, US Army/The Borden Institute.
- Stunkel, Leanne, and Christine Grady. 2011. “More Than the Money: A Review of the Literature Examining Healthy Volunteer Motivations.” Contemporary Clinical Trials 32: 342–352. doi: 10.1016/j.cct.2010.12.003
- Tengbeh, Angus Fayia, Luisa Enria, Elizabeth Smout, Thomas Mooney, Mike Callaghan, David Ishola, Bailah Leigh, et al. 2018. “‘We Are the Heroes Because We Are Ready to Die for This Country’: Participants’ Decision-making and Grounded Ethics in an Ebola Vaccine Clinical Trial.” Social Science and Medicine 203: 35–42. doi: 10.1016/j.socscimed.2018.03.008
- Twine, Susan M., Mireille D. Petit, Kelly M. Fulton, Robert V. House, and J. Wayne Conlan. 2010. “Immunoproteomics Analysis of the Murine Antibody Response to Vaccination with an Improved Francisella Tularensis Live Vaccine Strain (LVS).” PLOS One. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010000.
- West-Oram, Peter G. N., and Alena Buyx. 2017. “Global Health Solidarity.” Public Health Ethics 10 (2): 212–224.
- WHO. 2007. A Safer Future: Global Public Health Security in the 21st Century. Geneva: World Health Organization.
- WHO. 2009. Research Ethics in International Epidemic Response: WHO Technical Consultation. Geneva: World Health Organization.
- WHO. 2014a. Ethical Considerations for use of Unregistered Interventions for Ebola Virus Disease (EVD). World Health Organization. http://www.who.int/mediacentre/news/statements/2014/ebola-ethical-review-summary/en/.
- WHO. 2014b. Ethical Considerations for use of Unregistered Interventions for Ebola Viral Disease: Report of an Advisory Panel to WHO . WHO/HIS/KER/GHE/14.1. Geneva: World Health Organization.
- WHO. 2015a. Ebola Situation Report—28 January 2015. World Health Organization. http://apps.who.int/ebola/en/ebola-situation-report/situation-reports/ebola-situation-report-28-january-2015.
- WHO. 2015b. Report of the Ebola Interim Assessment Panel. World Health Organization. http://www.who.int/csr/resources/publications/ebola/report-by-panel.pdf.
- WHO. 2015c. World on the Verge of an Effective Ebola Vaccine. World Health Organization. http://www.who.int/mediacentre/news/releases/2015/effective-ebola-vaccine/en/.
- WHO. 2016a. Ebola Situation Report—30 March 2016. World Health Organization. http://apps.who.int/ebola/current-situation/ebola-situation-report-30-march-2016.
- WHO. 2016b. Guidance for Managing Ethical Issues in Infectious Disease Outbreaks. Geneva: World Health Organization.
- WHO. 2018a. A Research and Development Blueprint for Action to Prevent Epidemics. World Health Organization. Accessed 27 April. http://www.who.int/blueprint/en/.
- WHO. 2018b. List of Blueprint Priority Diseases. World Health Organization. Accessed 27 April. http://www.who.int/blueprint/priority-diseases/en/.
- Withers, Iain. 2018. “Are We Prepared for the Next Ebola-scale Epidemic?” The Telegraph, February 1. http://www.telegraph.co.uk/business/0/prepared-next-ebola-scale-epidemic/.
- WMA. 1964. WMA Declaration of Helsinki—Ethical Principles for Medical Research Involving Human Subjects. Last amended in 2013. World Medical Association. https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects.
- Yasinski, Emma. 2018. “Study Questions Animal Efficacy Data Behind Trials.” Science 360 (6385): 142. doi: 10.1126/science.360.6385.142
- Zitner, Aaron. 2001. “Taking a Germ Bullet.” Los Angeles Times, November 28, A2.