REFERENCES
- Applegate , E. A. and Grivetti , L. E. 1997 . Search for the competitive edge: A history of dietary fads and supplements . J. Nutr. , 127 : 869S – 873S . [PUBMED] [INFOTRIEVE] [CSA]
- Lamb , D. R. and Williams , M. H. , eds. 1991 . Perspectives in Exercise Science and Sports Medicine, Volume 4: Ergogenics-Enhancement of Performance in Exercise and Sport , Dubuque, IA : Wm. C. Brown Publishers .
- Williams , M. H. 1998 . The Ergogenics Edge: Pushing the Limits of Sports Performance , Champaign, IL : Human Kinetics .
- Bahrke , M. S. and Yesalis , C. E. , eds. 2002 . Performance-Enhancing Substances in Sport and Exercise , Champaign, IL : Human Kinetics .
- Mottram , D. R. 1999 . Banned drugs in sport. Does the International Olympic Committee (IOC) list need updating? . Sports Med. , 27 : 1 – 10 . [PUBMED] [INFOTRIEVE] [CSA]
- Ahrendt , D. M. 2001 . Ergogenic aids: Counseling the athlete . Am. Fam. Physician , 63 : 913 – 922 . [PUBMED] [INFOTRIEVE] [CSA]
- Chou , T. M. and Benowitz , N. L. 1994 . Caffeine and coffee: Effects on health and cardiovascular disease . Comp. Biochem. Physiol. C. Pharmacol. Toxicol. Endocrinol. , 109 : 173 – 189 . [PUBMED] [INFOTRIEVE] [CSA]
- James , J. E. 1997 . Is habitual caffeine use a preventable cardiovascular risk factor? . Lancet , 349 : 279 – 281 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Golding , J. 1995 . Reproduction and caffeine consumption—A literature review . Early Hum. Dev. , 43 : 1 – 14 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Heaney , R. P. 2002 . Effects of caffeine on bone and the calcium economy . Food Chem. Toxicol. , 40 : 1263 – 1270 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Pozniak , P. C. 1985 . The carcinogenicity of caffeine and coffee: A review . J. Am. Diet. Assoc. , 85 : 1127 – 1133 . [PUBMED] [INFOTRIEVE] [CSA]
- Kruger , A. 1996 . Chronic psychiatric patients' use of caffeine: Pharmacological effects and mechanisms . Psychol. Rep. , 78 : 915 – 923 . [PUBMED] [INFOTRIEVE] [CSA]
- Holtzman , S. G. 1990 . Caffeine as a model drug of abuse . Trends Pharmacol. Sci. , 11 : 355 – 356 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Ross , G. W. , Abbott , R. D. , Petrovitch , H. , Morens , D. M. , Grandinetti , A. , Tung , K. H. , Tanner , C. M. , Masaki , K. H. , Blanchette , P. L. , Curb , J. D. , Popper , J. S. and White , L. R. 2000 . Association of coffee and caffeine intake with the risk of Parkinson disease . J. Am. Med. Assoc. , 283 : 2674 – 2679 . [CSA] [CROSSREF]
- Schwarzschild , M. A. , Chen , J. F. and Ascherio , A. 2002 . Caffeinated clues and the promise of adenosine A2A antagonists in PD . Neurology , 58 : 1154 – 1160 . [PUBMED] [INFOTRIEVE] [CSA]
- Curatolo , P. W. and Robertson , D. 1983 . The health consequences of caffeine . Ann. Intern. Med. , 98 : 641 – 653 . [PUBMED] [INFOTRIEVE] [CSA]
- Gilbert , R. M. 1984 . “ Caffeine consumption ” . In The Methylxanthine Beverages and Foods: Chemistry, Consumption, and Health Effects , Edited by: Spiller , G. A. 185 – 213 . New York : Alan R. Liss, Inc .
- Barone , J. J. and Roberts , H. R. 1996 . Caffeine consumption . Food Chem. Toxicol. , 34 : 119 – 129 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Waldvogel , S. R. 2003 . Caffeine—A drug with a surprise . Angew. Chem. Int. Ed. Engl. , 42 : 604 – 605 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Granados-Soto , V. and Castaneda-Hernandez , G. 1999 . A review of the pharmacokinetic and pharmacodynamic factors in the potentiation of the antinociceptive effect of nonsteroidal anti-inflammatory drugs by caffeine . J. Pharmacol. Toxicol. Methods , 42 : 67 – 72 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Sawynok , J. 1995 . Pharmacological rationale for the clinical use of caffeine . Drugs , 49 : 37 – 50 . [PUBMED] [INFOTRIEVE] [CSA]
- Harland , B. F. 2000 . Caffeine and nutrition . Nutrition , 16 : 522 – 526 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Brice , C. F. and Smith , A. P. 2002 . Factors associated with caffeine consumption . Int. J. Food Sci. Nutr. , 53 : 55 – 64 . [PUBMED] [INFOTRIEVE] [CSA]
- Gray , J. 1998 . Caffeine, coffee, and health . Nutr. Food Sci , 98 : 314 – 319 . [CSA] [CROSSREF]
- Mandel , H. G. 2002 . Update on caffeine consumption, disposition, and action . Food Chem. Toxicol. , 40 : 1231 – 1234 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Donovan , J. L. and De Vane , C. L. 2001 . A primer on caffeine pharmacology and its drug interactions in clinical psychopharmacology . Psychopharmacol. Bull. , 35 : 30 – 48 . [PUBMED] [INFOTRIEVE] [CSA]
- Fredholm , B. B. , Battig , K. , Holmen , J. , Nehlig , A. and Zvartau , E. E. 1999 . Actions of caffeine in the brain with special reference to factors that contribute to its widespread use . Pharmacol. Rev. , 51 : 83 – 133 . [PUBMED] [INFOTRIEVE] [CSA]
- Melia , P. , Pipe , A. and Greenberg , L. 1996 . The use of anabolic-androgenic steroids by Canadian students . Clin. J. Sport Med. , 6 : 9 – 14 . [PUBMED] [INFOTRIEVE] [CSA]
- Forman , E. S. , Dekker , A. H. , Javors , J. R. and Davison , D. T. 1995 . High-risk behaviors in teenage male athletes . Clin. J. Sport Med. , 5 : 36 – 42 . [PUBMED] [INFOTRIEVE] [CSA]
- Wagner , J. C. 1991 . Enhancement of athletic performance with drugs. An overview . Sports Med. , 12 : 250 – 265 . [PUBMED] [INFOTRIEVE] [CSA]
- Rogers , C. C. 1985 . Cyclists try caffeine suppositories . Phys. Sportsmed. , 13 : 38 – 40 . [CSA]
- Nehlig , A. and Debry , G. 1994 . Caffeine and sports activity: A review . Int. J. Sports Med. , 15 : 215 – 223 . [PUBMED] [INFOTRIEVE] [CSA]
- Jones , A. R. and Pichot , J. T. 1998 . Stimulant Use in sports . Am. J. Addict. , 7 : 243 – 255 . [PUBMED] [INFOTRIEVE] [CSA]
- Delbeke , F. T. and Debackere , M. 1984 . Caffeine: Use and abuse in sports . Int. J. Sports Med. , 5 : 179 – 182 . [PUBMED] [INFOTRIEVE] [CSA]
- Spriet , L. L. 1995 . Caffeine and performance . Int. J. Sport Nutr. , 5 : S84 – 99 . Suppl[PUBMED] [INFOTRIEVE] [CSA]
- Rivers , W. H.R. and Webber , H. N. 1907 . The action of caffeine on the capacity for muscular work . J. Physiol. , 36 : 33 – 47 . [CSA]
- Foltz , E. E. , Ivy , A. C. and Barborka , C. J. 1943 . The influence of amphetamine (benzedrine) sulfate, d-desoxyephedrine hydrochloride (pervitin), and caffeine upon work output and recovery when rapidly exhausting work is done by trained subjects . Lab. Clin. Med. , 28 : 603 – 606 . [CSA]
- Foltz , E. E. , Schiffrin , M. J. and Ivy , A. C. 1943 . The influence of amphetamine (benzedrine) sulfate and caffeine on the performance of rapidly exhausting work by untrained subjects . Lab. Clin. Med. , 28 : 601 – 603 . [CSA]
- Weiss , B. and Laties , V. G. 1962 . Enhancement of human performance by caffeine and the amphetamines . Pharmacol. Rev. , 14 : 1 – 36 . [PUBMED] [INFOTRIEVE] [CSA]
- Costill , D. L. , Dalsky , G. P. and Fink , W. J. 1978 . Effects of caffeine ingestion on metabolism and exercise performance . Med. Sci. Sports , 10 : 155 – 158 . [PUBMED] [INFOTRIEVE] [CSA]
- Ivy , J. L. , Costill , D. L. , Fink , W. J. and Lower , R. W. 1979 . Influence of caffeine and carbohydrate feedings on endurance performance . Med. Sci. Sports , 11 : 6 – 11 . [PUBMED] [INFOTRIEVE] [CSA]
- Essig , D. , Costill , D. L. and Van Handel , P. J. 1980 . Effects of caffeine ingestion on utilization of muscle glycogen and lipid during leg ergometer cycling . Int. J. Sports Med. , 1 : 86 – 90 . [CSA]
- Graham , T. E. and Spriet , L. L. 1991 . Performance and metabolic responses to a high caffeine dose during prolonged exercise . J. Appl. Physiol. , 71 : 2292 – 2298 . [PUBMED] [INFOTRIEVE] [CSA]
- Spriet , L. L. , MacLean , D. A. , Dyck , D. J. , Hultman , E. , Cederblad , G. and Graham , T. E. 1992 . Caffeine ingestion and muscle metabolism during prolonged exercise in humans . Am. J. Physiol. , 262 : E891 – 898 . [PUBMED] [INFOTRIEVE] [CSA]
- Wilcox , A. R. 1990 . Caffeine and endurance performance . Sports Sci. Exch. , 3 : 1 – 5 . [CSA]
- Conlee , R. K. 1991 . “ Amphetamine, caffeine, and cocaine ” . In Perspectives in Exercise Science and Sports Medicine, Volume 4: Ergogenics—Enhancement of Performance in Exercise and Sport , Edited by: Lamb , D. R. and Williams , M. H. 285 – 330 . Dubuque, IA : Wm. C. Brown Publishers .
- Clarkson , P. M. 1993 . Nutritional ergogenic aids: Caffeine . Int. J. Sport Nutr. , 3 : 103 – 111 . [PUBMED] [INFOTRIEVE] [CSA]
- Graham , T. E. , Rush , J. W. and van Soeren , M. H. 1994 . Caffeine and exercise: Metabolism and performance . Can. J. Appl. Physiol. , 19 : 111 – 138 . [PUBMED] [INFOTRIEVE] [CSA]
- Graham , T. E. and Spriet , L. L. 1996 . Caffeine and exercise performance . Sports Sci. Exch. , 9 : 1 – 5 . [CSA]
- Spriet , L. L. 1997 . “ Ergogenic aids: Recent advances and retreats ” . In Perspectives in Exercise Science and Sports Medicine, Volume 10: Optimizing Sport Performance , Edited by: Lamb , D. R. and Murray , R. 185 – 238 . Carmel, IN : Cooper Publishing Group .
- Spriet , L. L. and Graham , T. E. 1999 . Caffeine and exercise performance . Curr. Comm. ACSM , : 1 – 3 . July[CSA]
- Spriet , L. L. and Hewlett , R. A. 2000 . “ Caffeine ” . In Nutrition in Sport , Edited by: Maughan , R. J. 379 – 392 . Oxford : Blackwell Science Ltd .
- Graham , T. E. 2001 . Caffeine and exercise: Metabolism, endurance, and performance . Sports Med. , 31 : 785 – 807 . [PUBMED] [INFOTRIEVE] [CSA]
- Graham , T. E. 2001 . Caffeine, coffee, and ephedrine: Impact on exercise performance and metabolism . Can. J. Appl. Physiol. , 26 : S103 – 119 . Suppl[PUBMED] [INFOTRIEVE] [CSA]
- Williams , J. H. 1991 . Caffeine. neuromuscular function, and high-intensity exercise performance . Sports Med. Phys. Fitness , 31 : 481 – 489 . [CSA]
- Tarnopolsky , M. A. 1994 . Caffeine and endurance performance . Sports Med. , 18 : 109 – 125 . [PUBMED] [INFOTRIEVE] [CSA]
- Sinclair , C. J. and Geiger , J. D. 2000 . Caffeine use in sports. A pharmacological review . J. Sports Med. Phys. Fitness , 40 : 71 – 79 . [PUBMED] [INFOTRIEVE] [CSA]
- Spriet , L. L. 2000 . “ Caffeine ” . In Performance-Enhancing Substances in Sport and Exercise , Edited by: Bahrke , M. S. and Yesalis , C. E. 267 – 278 . Champaign, IL : Human Kinetics .
- Paluska , S. A. 2003 . Caffeine and exercise . Curr. Sports Med. Rep. , 2 : 213 – 219 . [PUBMED] [INFOTRIEVE] [CSA]
- Magkos , F. and Kavouras , S. A. 2004 . “ Caffeine ” . In Nutritional Ergogenic Aids , Edited by: Wolinsky , I. and Driskell , J. A. 275 – 323 . Boca Raton, FL : CRC Press LLC .
- Greer , F. , McLean , C. and Graham , T. E. 1998 . Caffeine, performance, and metabolism during repeated Wingate exercise tests . J. Appl. Physiol. , 85 : 1502 – 1508 . [PUBMED] [INFOTRIEVE] [CSA]
- Armstrong , L. E. 2002 . Caffeine, body fluid-electrolyte balance, and exercise performance . Int. J. Sport Nutr. Exerc. Metab. , 12 : 189 – 206 . [PUBMED] [INFOTRIEVE] [CSA]
- Slavin , J. L. and Joensen , D. J. 1985 . Caffeine and sports performance . Phys. Sportsmed. , 13 : 191 – 193 . [CSA]
- Applegate , E. 1999 . Effective nutritional ergogenic aids . Int. J. Sport Nutr. , 9 : 229 – 239 . [PUBMED] [INFOTRIEVE] [CSA]
- Benowitz , N. L. 1990 . Clinical pharmacology of caffeine . Annu. Rev. Med. , 41 : 277 – 288 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Arnaud , M. J. 1987 . The pharmacology of caffeine . Prog. Drug Res. , 31 : 273 – 313 . [PUBMED] [INFOTRIEVE] [CSA]
- Leonard , T. K. , Watson , R. R. and Mohs , M. E. 1987 . The effects of caffeine on various body systems: A review . J. Am. Diet. Assoc. , 87 : 1048 – 1053 . [PUBMED] [INFOTRIEVE] [CSA]
- Jang , G. R. , Harris , R. Z. and Lau , D. T. 2001 . Pharmacokinetics and its role in small molecule drug discovery research . Med. Res. Rev. , 21 : 382 – 396 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Eteng , M. U. , Eyong , E. U. , Akpanyung , E. O. , Agiang , M. A. and Aremu , C. Y. 1997 . Recent advances in caffeine and theobromine toxicities: A review . Plant Foods Hum. Nutr. , 51 : 231 – 243 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Mumford , G. K. , Benowitz , N. L. , Evans , S. M. , Kaminski , B. J. , Preston , K. L. , Sannerud , C. A. , Silverman , K. and Griffiths , R. R. 1996 . Absorption rate of methylxanthines following capsules, cola and chocolate . Eur. J. Clin. Pharmacol. , 51 : 319 – 325 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Liguori , A. , Hughes , J. R. and Grass , J. A. 1997 . Absorption and subjective effects of caffeine from coffee, cola, and capsules . Pharmacol. Biochem. Behav. , 58 : 721 – 726 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Marks , V. and Kelly , J. F. 1973 . Absorption of caffeine from tea, coffee, and coca cola . Lancet , 1 : 827 [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Blanchard , J. and Sawers , S. J. 1983 . The absolute bioavailability of caffeine in man . Eur. J. Clin. Pharmacol. , 24 : 93 – 98 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Bonati , M. , Latini , R. , Galletti , F. , Young , J. F. , Tognoni , G. and Garattini , S. 1982 . Caffeine disposition after oral doses . Clin. Pharmacol. Ther. , 32 : 98 – 106 . [PUBMED] [INFOTRIEVE] [CSA]
- Kamimori , G. H. , Karyekar , C. S. , Otterstetter , R. , Cox , D. S. , Balkin , T. J. , Belenky , G. L. and Eddington , N. D. 2002 . The rate of absorption and relative bioavailability of caffeine administered in chewing gum versus capsules to normal healthy volunteers . Int. J. Pharm. , 234 : 159 – 167 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Miners , J. O. and Birkett , D. J. 1996 . The use of caffeine as a metabolic probe for human drug metabolizing enzymes . Gen. Pharmacol. , 27 : 245 – 249 . [PUBMED] [INFOTRIEVE] [CSA]
- Fredholm , B. B. 1985 . On the mechanism of action of theophylline and caffeine . Acta Med. Scand. , 217 : 149 – 153 . [PUBMED] [INFOTRIEVE] [CSA]
- Cheng , W. S. , Murphy , T. L. , Smith , M. T. , Cooksley , W. G. , Halliday , J. W. and Powell , L. W. 1990 . Dose-dependent pharmacokinetics of caffeine in humans: Relevance as a test of quantitative liver function . Clin. Pharmacol. Ther. , 47 : 516 – 524 . [PUBMED] [INFOTRIEVE] [CSA]
- Carrillo , J. A. and Benitez , J. 2000 . Clinically significant pharmacokinetic interactions between dietary caffeine and medications . Clin. Pharmacokinet. , 39 : 127 – 153 . [PUBMED] [INFOTRIEVE] [CSA]
- McLean , C. and Graham , T. E. 2002 . Effects of exercise and thermal stress on caffeine pharmacokinetics in men and eumenorrheic women . J. Appl. Physiol. , 93 : 1471 – 1478 . [PUBMED] [INFOTRIEVE] [CSA]
- Kamimori , G. H. , Lugo , S. I. , Penetar , D. M. , Chamberlain , A. C. , Brunhart , G. E. , Brunhart , A. E. and Eddington , N. D. 1995 . Dose-dependent caffeine pharmacokinetics during severe sleep deprivation in humans . Int. J. Clin. Pharmacol. Ther. , 33 : 182 – 186 . [PUBMED] [INFOTRIEVE] [CSA]
- Kamimori , G. H. , Penetar , D. M. , Headley , D. B. , Thorne , D. R. , Otterstetter , R. and Belenky , G. 2000 . Effect of three caffeine doses on plasma catecholamines and alertness during prolonged wakefulness . Eur. J. Clin. Pharmacol. , 56 : 537 – 544 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Robertson , D. , Frolich , J. C. , Carr , R. K. , Watson , J. T. , Hollifield , J. W. , Shand , D. G. and Gates , J. A. 1978 . Effects of caffeine on plasma renin activity, catecholamines and blood pressure . N. Engl. J. Med. , 298 : 181 – 186 . [PUBMED] [INFOTRIEVE] [CSA]
- Robertson , D. , Wade , D. , Workman , R. , Woosley , R. L. and Gates , J. A. 1981 . Tolerance to the humoral and hemodynamic effects of caffeine in man . J. Clin. Invest. , 67 : 1111 – 1117 . [PUBMED] [INFOTRIEVE] [CSA]
- Bellet , S. , Kershbaum , A. and Finck , E. M. 1968 . Response of free fatty acids to coffee and caffeine . Metabolism , 17 : 702 – 707 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Carrillo , J. A. , Christensen , M. , Ramos , S. I. , Aim , C. , Dahl , M. L. , Benitez , J. and Bertilsson , L. 2000 . Evaluation of caffeine as an in vivo probe for CYP1A2 using measurements in plasma, saliva, and urine . Ther. Drug Monit. , 22 : 409 – 417 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Zylber-Katz , E. , Granit , L. and Levy , M. 1984 . Relationship between caffeine concentrations in plasma and saliva . Clin. Pharmacol. Ther. , 36 : 133 – 137 . [PUBMED] [INFOTRIEVE] [CSA]
- Graham , T. E. and Spriet , L. L. 1995 . Metabolic, catecholamine, and exercise performance responses to various doses of caffeine . J. Appl. Physiol. , 78 : 867 – 874 . [PUBMED] [INFOTRIEVE] [CSA]
- Collomp , K. , Anselme , F. , Audran , M. , Gay , J. P. , Chanal , J. L. and Prefaut , C. 1991 . Effects of moderate exercise on the pharmacokinetics of caffeine . Eur. J. Clin. Pharmacol. , 40 : 279 – 282 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Lelo , A. , Birkett , D. J. , Robson , R. A. and Miners , J. O. 1986 . Comparative pharmacokinetics of caffeine and its primary demethylated metabolites paraxanthine, theobromine, and theophylline in man . Br. J. Clin. Pharmacol. , 22 : 177 – 182 . [PUBMED] [INFOTRIEVE] [CSA]
- Kennedy , J. S. , Leduc , B. W. , Scavone , J. M. , Harmatz , J. S. , Shader , R. I. and Greenblatt , D. J. 1987 . Pharmacokinetics of intravenous caffeine: Comparison of high-performance liquid chromatographic and gas chromatographic methods . J. Chromatogr. , 422 : 274 – 280 . [PUBMED] [INFOTRIEVE] [CSA]
- Newton , R. , Broughton , L. J. , Lind , M. J. , Morrison , P. J. , Rogers , H. J. and Bradbrook , I. D. 1981 . Plasma and salivary pharmacokinetics of caffeine in man . Eur. J. Clin. Pharmacol. , 21 : 45 – 52 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Stable , L. , Arner , P. and Ungerstedt , U. 1991 . Drug distribution studies with microdialysis. III: Extracellular concentration of caffeine in adipose tissue in man . Life Sci. , 49 : 1853 – 1858 . [CSA] [CROSSREF]
- Stable , L. , Segersvard , S. and Ungerstedt , U. 1991 . Drug distribution studies with microdialysis. II. Caffeine and theophylline in blood, brain and other tissues in rats . Life Sci. , 49 : 1843 – 1852 . [CSA] [CROSSREF]
- Gonzalez-Jimenez , J. , Frutos , G. and Cayre , I. 1992 . Fluorescence quenching of human serum albumin by xanthines . Biochem. Pharmacol. , 44 : 824 – 826 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Burg , A. W. and Werner , E. 1972 . Tissue distribution of caffeine and its metabolites in the mouse . Biochem. Pharmacol. , 21 : 923 – 936 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Donoso , P. , O'Neill , S. C. , Dilly , K. W. , Negretti , N. and Eisner , D. A. 1994 . Comparison of the effects of caffeine and other methylxanthines on [Ca2+]i in rat ventricular myocytes . Br. J. Pharmacol. , 111 : 455 – 458 . [PUBMED] [INFOTRIEVE] [CSA]
- Hawke , T. J. , Allen , D. G. and Lindinger , M. I. 2000 . Paraxanthine, a caffeine metabolite, dose dependently increases [Ca2+]i in skeletal muscle . J. Appl. Physiol. , 89 : 2312 – 2317 . [PUBMED] [INFOTRIEVE] [CSA]
- Weinfeld , H. and Christman , A. A. 1953 . The metabolism of caffeine and theophylline . J. Biol. Chem. , 200 : 345 – 355 . [PUBMED] [INFOTRIEVE] [CSA]
- Cornish , H. H. and Christman , A. A. 1957 . A study of the metabolism of theobromine, theophylline, and caffeine in man . J. Biol. Chem. , 228 : 315 – 323 . [PUBMED] [INFOTRIEVE] [CSA]
- Somani , S. M. and Gupta , P. 1988 . Caffeine: A new look at an age-old drug . Int. J. Clin. Pharmacol. Ther. Toxicol. , 26 : 521 – 533 . [PUBMED] [INFOTRIEVE] [CSA]
- Lelo , A. , Miners , J. O. , Robson , R. A. and Birkett , D. J. 1986 . Quantitative assessment of caffeine partial clearances in man . Br. J. Clin. Pharmacol. , 22 : 183 – 186 . [PUBMED] [INFOTRIEVE] [CSA]
- Gu , L. , Gonzalez , F. J. , Kalow , W. and Tang , B. K. 1992 . Biotransformation of caffeine, paraxanthine, theobromine, and theophylline by cDNA-expressed human CYP1A2 and CYP2E1 . Pharmacogenetics , 2 : 73 – 77 . [PUBMED] [INFOTRIEVE] [CSA]
- Caubet , M. S. , Elbast , W. , Dubuc , M. C. and Brazier , J. L. 2002 . Analysis of urinary caffeine metabolites by HPLC-DAD: The use of metabolic ratios to assess CYP1A2 enzyme activity . J. Pharm. Biomed. Anal. , 27 : 261 – 270 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Ha , H. R. , Chen , J. , Krahenbuhl , S. and Follath , F. 1996 . Biotransformation of caffeine by cDNA-expressed human cytochromes P-450 . Eur. J. Clin. Pharmacol. , 49 : 309 – 315 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Butler , M. A. , Iwasaki , M. , Guengerich , F. P. and Kadlubar , F. F. 1989 . Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines . Proc. Natl. Acad. Sci. USA , 86 : 7696 – 7700 . [PUBMED] [INFOTRIEVE] [CSA]
- Fuhr , U. , Doehmer , J. , Battula , N. , Wolfel , C. , Kudla , C. , Keita , Y. and Staib , A. H. 1992 . Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms . Biochem. Pharmacol. , 43 : 225 – 235 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Anderson , B. J. , Gunn , T. R. , Holford , N. H. and Johnson , R. 1999 . Caffeine overdose in a premature infant: Clinical course and pharmacokinetics . Anaesth. Intensive Care , 27 : 307 – 311 . [PUBMED] [INFOTRIEVE] [CSA]
- Grant , D. M. , Campbell , M. E. , Tang , B. K. and Kalow , W. 1987 . Biotransformation of caffeine by microsomes from human liver. Kinetics and inhibition studies . Biochem. Pharmacol. , 36 : 1251 – 1260 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Berthou , F. , Flinois , J. P. , Ratanasavanh , D. , Beaune , P. , Riche , C. and Guillouzo , A. 1991 . Evidence for the involvement of several cytochromes P-450 in the first steps of caffeine metabolism by human liver microsomes . Drug Metab. Dispos. , 19 : 561 – 567 . [PUBMED] [INFOTRIEVE] [CSA]
- Rostami-Hodjegan , A. , Nurminen , S. , Jackson , P. R. and Tucker , G. T. 1996 . Caffeine urinary metabolite ratios as markers of enzyme activity: A theoretical assessment . Pharmacogenetics , 6 : 121 – 149 . [PUBMED] [INFOTRIEVE] [CSA]
- Tassaneeyakul , W. , Birkett , D. J. , McManus , M. E. , Veronese , M. E. , Andersson , T. , Tukey , R. H. and Miners , J. O. 1994 . Caffeine metabolism by human hepatic cytochromes P450: Contributions of 1A2, 2E1 and 3A isoforms . Biochem. Pharmacol. , 47 : 1767 – 1776 . [PUBMED] [INFOTRIEVE] [CSA]
- Bendriss , E. K. , Markoglou , N. and Wainer , I. W. 2000 . Liquid chromatographic method for the simultaneous determination of caffeine and fourteen caffeine metabolites in urine . J. Chromatogr. B Biomed. Sci. Appl. , 746 : 331 – 338 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Kalow , W. and Tang , B. K. 1993 . The use of caffeine for enzyme assays: A critical appraisal . Clin. Pharmacol. Ther. , 53 : 503 – 514 . [PUBMED] [INFOTRIEVE] [CSA]
- Chung , W. G. and Cha , Y. N. 1997 . Oxidation of caffeine to theobromine and theophylline is catalyzed primarily by flavin-containing monooxygenase in liver microsomes . Biochem. Biophys. Res. Commun. , 235 : 685 – 688 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Brachtel , D. and Richter , E. 1992 . Absolute bioavailability of caffeine from a tablet formulation . J. Hepatol. , 16 : 385 [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Busto , U. , Bendayan , R. and Sellers , E. M. 1989 . Clinical pharmacokinetics of non-opiate abused drugs . Clin. Pharmacokinet , 16 : 1 – 26 . [PUBMED] [INFOTRIEVE] [CSA]
- Kaplan , G. B. , Greenblatt , D. J. , Ehrenberg , B. L. , Goddard , J. E. , Cotreau , M. M. , Harmatz , J. S. and Shader , R. I. 1997 . Dose-dependent pharmacokinetics and psychomotor effects of caffeine in humans . J. Clin. Pharmacol. , 37 : 693 – 703 . [PUBMED] [INFOTRIEVE] [CSA]
- Callahan , M. M. , Robertson , R. S. , Arnaud , M. J. , Branfman , A. R. , McComish , M. F. and Yesair , D. W. 1982 . Human metabolism of [1-methyl-14C]- and [2-14C]caffeine after oral administration . Drug Metab. Dispos. , 10 : 417 – 423 . [PUBMED] [INFOTRIEVE] [CSA]
- Sato , J. , Nakata , H. , Owada , E. , Kikuta , T. , Umetsu , M. and Ito , K. 1993 . Influence of usual intake of dietary caffeine on single-dose kinetics of theophylline in healthy human subjects . Eur. J. Clin. Pharmacol , 44 : 295 – 298 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Denaro , C. P. , Brown , C. R. , Wilson , M. , Jacob , P. III and Benowitz , N. L. 1990 . Dose-dependency of caffeine metabolism with repeated dosing . Clin. Pharmacol. Ther. , 48 : 277 – 285 . [PUBMED] [INFOTRIEVE] [CSA]
- Benowitz , N. L. , Jacob , P. 3rd , Mayan , H. and Denaro , C. 1995 . Sympathomimetic effects of paraxanthine and caffeine in humans . Clin. Pharmacol. Ther. , 58 : 684 – 691 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Simon , T. , Becquemont , L. , Hamon , B. , Nouyrigat , E. , Chodjania , Y. , Poirier , J. M. , Funck-Brentano , C. and Jaillon , P. 2001 . Variability of cytochrome P450 1A2 activity over time in young and elderly healthy volunteers . Br. J. Clin. Pharmacol. , 52 : 601 – 604 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Rizzo , N. , Hispard , E. , Dolbeault , S. , Dally , S. , Leverge , R. and Girre , C. 1997 . Impact of long-term ethanol consumption on CYP1A2 activity . Clin. Pharmacol. Ther. , 62 : 505 – 509 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Kamimori , G. H. , Eddington , N. D. , Hoyt , R. W. , Fulco , C. S. , Lugo , S. , Durkot , M. J. , Brunhart , A. E. and Cymerman , A. 1995 . Effects of altitude (4300 m) on the pharmacokinetics of caffeine and cardio-green in humans . Eur. J. Clin. Pharmacol , 48 : 167 – 170 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Tantcheva-Poor , I. , Zaigler , M. , Rietbrock , S. and Fuhr , U. 1999 . Estimation of cytochrome P-450 CYP1A2 activity in 863 healthy Caucasians using a saliva-based caffeine test . Pharmacogenetics , 9 : 131 – 144 . [PUBMED] [INFOTRIEVE] [CSA]
- Vistisen , K. , Loft , S. and Poulsen , H. E. 1991 . Cytochrome P450 IA2 activity in man measured by caffeine metabolism: Effect of smoking, broccoli and exercise . Adv. Exp. Med. Biol. , 283 : 407 – 411 . [PUBMED] [INFOTRIEVE] [CSA]
- Vistisen , K. , Poulsen , H. E. and Loft , S. 1992 . Foreign compound metabolism capacity in man measured from metabolites of dietary caffeine . Carcinogenesis , 13 : 1561 – 1568 . [PUBMED] [INFOTRIEVE] [CSA]
- Lee , H. , Yeom , H. , Kim , Y. G. , Yoon , C. N. , Jin , C. , Choi , J. S. , Kim , B. R. and Kim , D. H. 1998 . Structure-related inhibition of human hepatic caffeine N3-demethylation by naturally occurring flavonoids . Biochem. Pharmacol , 55 : 1369 – 1375 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Carrillo , J. A. and Benitez , J. 1996 . CYP1A2 activity, gender and smoking, as variables influencing the toxicity of caffeine . Br. J. Clin. Pharmacol , 41 : 605 – 608 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Krul , C. and Hageman , G. 1998 . Analysis of urinary caffeine metabolites to assess biotransformation enzyme activities by reversed-phase high-performance liquid chromatography . J. Chromatogr. B Biomed. Sci. Appl. , 709 : 27 – 34 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Rump , A. F. , Siekmann , U. and Kalff , G. 1999 . Effects of hyperbaric and hyperoxic conditions on the disposition of drugs: Theoretical considerations and a review of the literature . Gen. Pharmacol. , 32 : 127 – 133 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Jurgens , G. , Christensen , H. R. , Brosen , K. , Sonne , J. , Loft , S. and Olsen , N. V. 2002 . Acute hypoxia and cytochrome P450-mediated hepatic drug metabolism in humans . Clin. Pharmacol. Ther. , 71 : 214 – 220 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Kamimori , G. H. , Joubert , A. , Otterstetter , R. , Santaromana , M. and Eddington , N. D. 1999 . The effect of the menstrual cycle on the pharmacokinetics of caffeine in normal, healthy eumenorrheic females . Eur. J. Clin. Pharmacol. , 55 : 445 – 449 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Lane , J. D. , Steege , J. F. , Rupp , S. L. and Kuhn , C. M. 1992 . Menstrual cycle effects on caffeine elimination in the human female . Eur. J. Clin. Pharmacol. , 43 : 543 – 546 . [PUBMED] [INFOTRIEVE] [CSA]
- Kamimori , G. H. , Somani , S. M. , Knowlton , R. G. and Perkins , R. M. 1987 . The effects of obesity and exercise on the pharmacokinetics of caffeine in lean and obese volunteers . Eur. J. Clin. Pharmacol , 31 : 595 – 600 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Caraco , Y. , Zylber-Katz , E. , Berry , E. M. and Levy , M. 1995 . Caffeine pharmacokinetics in obesity and following significant weight reduction . Int. J. Obes. Relat. Metab. Disord. , 19 : 234 – 239 . [PUBMED] [INFOTRIEVE] [CSA]
- Rietveld , E. C. , Broekman , M. M. , Houben , J. J. , Eskes , T. K. and van Rossum , J. M. 1984 . Rapid onset of an increase in caffeine residence time in young women due to oral contraceptive steroids . Eur. J. Clin. Pharmacol. , 26 : 371 – 373 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Abernethy , D. R. and Todd , E. L. 1985 . Impairment of caffeine clearance by chronic use of low-dose oestrogen-containing oral contraceptives . Eur. J. Clin. Pharmacol. , 28 : 425 – 428 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Patwardhan , R. V. , Desmond , P. V. , Johnson , R. F. and Schenker , S. 1980 . Impaired elimination of caffeine by oral contraceptive steroids . J. Lab. Clin. Med. , 95 : 603 – 608 . [PUBMED] [INFOTRIEVE] [CSA]
- Schrenk , D. , Brockmeier , D. , Morike , K. , Bock , K. W. and Eichelbaum , M. 1998 . A distribution study of CYP1A2 phenotypes among smokers and non-smokers in a cohort of healthy Caucasian volunteers . Eur. J. Clin. Pharmacol , 53 : 361 – 367 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Aldridge , A. , Bailey , J. and Neims , A. H. 1981 . The disposition of caffeine during and after pregnancy . Semin. Perinatol , 5 : 310 – 314 . [PUBMED] [INFOTRIEVE] [CSA]
- Tsutsumi , K. , Kotegawa , T. , Matsuki , S. , Tanaka , Y. , Ishii , Y. , Kodama , Y. , Kuranari , M. , Miyakawa , I. and Nakano , S. 2001 . The effect of pregnancy on cytochrome P4501A2, xanthine oxidase, and N-acetyltransferase activities in humans . Clin. Pharmacol. Ther , 70 : 121 – 125 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Knutti , R. , Rothweiler , H. and Schlatter , C. 1981 . Effect of pregnancy on the pharmacokinetics of caffeine . Eur. J. Clin. Pharmacol , 21 : 121 – 126 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Knutti , R. , Rothweiler , H. and Schlatter , C. 1982 . The effect of pregnancy on the pharmacokinetics of caffeine . Arch. Toxicol. Suppl , 5 : 187 – 192 . [PUBMED] [INFOTRIEVE] [CSA]
- Parsons , W. D. and Neims , A. H. 1978 . Effect of smoking on caffeine clearance . Clin. Pharmacol. Ther , 24 : 40 – 45 . [PUBMED] [INFOTRIEVE] [CSA]
- Butler , M. A. , Lang , N. P. , Young , J. F. , Caporaso , N. E. , Vineis , P. , Hayes , R. B. , Teitel , C. H. , Massengill , J. P. , Lawsen , M. F. and Kadlubar , F. F. 1992 . Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites . Pharmacogenetics , 2 : 116 – 127 . [PUBMED] [INFOTRIEVE] [CSA]
- de Leon , J. , Diaz , F. J. , Rogers , T. , Browne , D. , Dinsmore , L. , Ghosheh , O. H. , Dwoskin , L. P. and Crooks , P. A. 2003 . A pilot study of plasma caffeine concentrations in a US sample of smoker and nonsmoker volunteers . Prog. Neuropsychopharmacol. Biol. Psychiatry , 27 : 165 – 171 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Benowitz , N. L. , Hall , S. M. and Modin , G. 1989 . Persistent increase in caffeine concentrations in people who stop smoking . Br. Med. J , 298 : 1075 – 1076 . [CSA]
- Aranda , J. V. , Louridas , A. T. , Vitullo , B. B. , Thorn , P. , Aldridge , A. and Haber , R. 1979 . Metabolism of theophylline to caffeine in human fetal liver . Science , 206 : 1319 – 1321 . [PUBMED] [INFOTRIEVE] [CSA]
- Bory , C. , Baltassat , P. , Porthault , M. , Bethenod , M. , Frederich , A. and Aranda , J. V. 1978 . Biotransformation of theophylline to caffeine in premature newborn . Lancet , 2 : 1204 – 1205 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Bory , C. , Baltassat , P. , Porthault , M. , Bethenod , M. , Frederich , A. and Aranda , J. V. 1979 . Metabolism of theophylline to caffeine in premature newborn infants . J. Pediatr , 94 : 988 – 993 . [PUBMED] [INFOTRIEVE] [CSA]
- Bada , H. S. , Khanna , N. N. , Somani , S. M. and Tin , A. A. 1979 . Interconversion of theophylline and caffeine in newborn infants . J. Pediatr , 94 : 993 – 995 . [PUBMED] [INFOTRIEVE] [CSA]
- Boutroy , M. J. , Vert , P. , Royer , R. J. , Monin , P. and Royer-Morrot , M. J. 1979 . Caffeine, a metabolite of theophylline during the treatment of apnea in the premature infant . J. Pediatr , 94 : 996 – 998 . [PUBMED] [INFOTRIEVE] [CSA]
- Sonnier , M. and Cresteil , T. 1998 . Delayed ontogenesis of CYP1A2 in the human liver . Eur. J. Biochem. , 251 : 893 – 898 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Aranda , J. V. , Collinge , J. M. , Zinman , R. and Watters , G. 1979 . Maturation of caffeine elimination in infancy . Arch. Dis. Child , 54 : 946 – 949 . [PUBMED] [INFOTRIEVE] [CSA]
- Parsons , W. D. and Neims , A. H. 1981 . Prolonged half-life of caffeine in healthy tern newborn infants . J. Pediatr , 98 : 640 – 641 . [PUBMED] [INFOTRIEVE] [CSA]
- Aldridge , A. , Aranda , J. V. and Neims , A. H. 1979 . Caffeine metabolism in the newborn . Clin. Pharmacol. Ther , 25 : 447 – 453 . [PUBMED] [INFOTRIEVE] [CSA]
- Rasmussen , B. B. , Brix , T. H. , Kyvik , K. O. and Brosen , K. 2002 . The interindividual differences in the 3-demethylation of caffeine alias CYP1A2 is determined by both genetic and environmental factors . Pharmacogenetics , 12 : 473 – 478 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Grant , D. M. , Tang , B. K. and Kalow , W. 1983 . Variability in caffeine metabolism . Clin. Pharmacol. Ther , 33 : 591 – 602 . [PUBMED] [INFOTRIEVE] [CSA]
- Birkett , D. J. and Miners , J. O. 1991 . Caffeine renal clearance and urine caffeine concentrations during steady state dosing. Implications for monitoring caffeine intake during sports events . Br. J. Clin. Pharmacol , 31 : 405 – 408 . [PUBMED] [INFOTRIEVE] [CSA]
- Duthel , J. M. , Vallon , J. J. , Martin , G. , Ferret , J. M. , Mathieu , R. and Videman , R. 1991 . Caffeine and sport: Role of physical exercise upon elimination . Med. Sci. Sports Exerc , 23 : 980 – 985 . [PUBMED] [INFOTRIEVE] [CSA]
- van , d er , Merwe , P. J. , Luus , H. G. and Barnard , J. G. 1992 . Caffeine in sport. Influence of endurance exercise on the urinary caffeine concentration . Int. J. Sports Med , 13 : 74 – 76 . [CSA]
- Tang-Liu , D. D. , Williams , R. L. and Riegelman , S. 1983 . Disposition of caffeine and its metabolites in man . J. Pharmacol. Exp. Ther , 224 : 180 – 185 . [PUBMED] [INFOTRIEVE] [CSA]
- Delbeke , F. T. and Debackere , M. 1998 . The influence of diuretics on the excretion and metabolism of doping agents. Part IV—Caffeine . Biopharm. Drug Dispos , 9 : 137 – 145 . [CSA]
- Sinues , B. , Fanlo , A. , Bernal , M. L. , Mayayo , E. , Soriano , M. A. and Martinez-Ballarin , E. 2000 . Influence of the urine flow rate on some caffeine metabolite ratios used to assess CYP1A2 activity . Ther. DrugMonit , 24 : 715 – 721 . [CSA] [CROSSREF]
- van , d er , Merwe , P. J. , Muller , F. R. and Muller , F. O. 1988 . Caffeine in sport. Urinary excretion of caffeine in healthy volunteers after intake of common caffeine-containing beverages . S. Afr. Med. J , 74 : 163 – 164 . [CSA]
- Clarkson , P. M. 1996 . Nutrition for improved sports performance. Current issues on ergogenic aids . Sports Med , 21 : 393 – 401 . [PUBMED] [INFOTRIEVE] [CSA]
- Van Soeren , M. H. , Sathasivam , P. , Spriet , L. L. and Graham , T. E. 1993 . Caffeine metabolism and epinephrine responses during exercise in users and nonusers . J. Appl. Physiol. , 75 : 805 – 812 . [PUBMED] [INFOTRIEVE] [CSA]
- Pasman , W. J. , van Baak , M. A. , Jeukendrup , A. E. and de Haan , A. 1995 . The effect of different dosages of caffeine on endurance performance time . Int. J. Sports Med , 16 : 225 – 230 . [PUBMED] [INFOTRIEVE] [CSA]
- Wagner , J. C. 1990 . How much caffeine is too much in athletes? . Am. J. Hosp. Pharm , 47 : 303 [CSA]
- Conway , K. J. , Orr , R. and Stannard , S. R. 2003 . Effect of a divided caffeine dose on endurance cycling performance, postexercise urinary caffeine concentration, and plasma paraxanthine . J. Appl. Physiol. , 94 : 1557 – 1562 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Associated Press . 2003 . Revised banned list will be in force for Athens. ESPN Internet Ventures. http://espn.go.com/oly/news/2003/0917/1617822.html
- Hetzler , R. K. , Knowlton , R. G. , Somani , S. M. , Brown , D. D. and Perkins , R. M. III . 1990 . Effect of paraxanthine on FFA mobilization after intravenous caffeine administration in humans . J. Appl. Physiol. , 68 : 44 – 47 . [PUBMED] [INFOTRIEVE] [CSA]
- Greer , F. , Friars , D. and Graham , T. E. 2000 . Comparison of caffeine and theophylline ingestion: Exercise metabolism and endurance . J. Appl. Physiol. , 89 : 1837 – 1844 . [PUBMED] [INFOTRIEVE] [CSA]
- Raguso , C. A. , Coggan , A. R. , Sidossis , L. S. , Gastaldelli , A. and Wolfe , R. R. 1996 . Effect of theophylline on substrate metabolism during exercise . Metabolism , 45 : 1153 – 1160 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Johansson , B. , Georgiev , V. , Kuosmanen , T. and Fredholm , B. B. 1996 . Long-term treatment with some methylxanthines decreases the susceptibility to bicuculline- and pentylenetetrazol-induced seizures in mice. Relationship to c-fos expression and receptor binding . Eur. J. Neurosci , 8 : 2447 – 2458 . [PUBMED] [INFOTRIEVE] [CSA]
- Veley , V. H. and Waller , A. D. 1910 . On the comparative toxicity of theobromine and caffeine, as measured by their direct effect upon the contractility of isolated muscle . Proc. R. Soc. Lond. B Biol. Sci , 82 : 568 – 574 . [CSA]
- Axelsson , J. and Thesleff , S. 1958 . Activation of the contractile mechanism in striated muscle . Acta Physiol. Scand , 44 : 55 – 66 . [PUBMED] [INFOTRIEVE] [CSA]
- Conway , D. and Sakai , T. 1960 . Caffeine contracture . Proc. Natl. Acad. Sci. USA , 46 : 897 – 903 . [CSA]
- Sandow , A. , Taylor , S. R. , Isaacson , A. and Seguin , J. J. 1964 . Electrochemical coupling in potentiation of muscular contraction . Science , 143 : 577 – 579 . [PUBMED] [INFOTRIEVE] [CSA]
- Yamaguchi , T. 1975 . Caffeine-induced potentiation of twitches in frog single muscle fiber . Jpn. J. Physiol. , 25 : 693 – 704 . [PUBMED] [INFOTRIEVE] [CSA]
- Luttgau , H. C. and Oetliker , H. 1968 . The action of caffeine on the activation of the contractile mechanism in straited muscle fibers . J. Physiol. , 194 : 51 – 74 . [PUBMED] [INFOTRIEVE] [CSA]
- Gutmann , E. and Sandow , A. 1965 . Caffeine-induced contracture and potentiation of contraction in normal and denervated rat muscle . Life Sci. , 4 : 1149 – 1156 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Weber , A. and Herz , R. 1968 . The relationship between caffeine contracture of intact muscle and the effect of caffeine on reticulum . Gen. Physiol. , 52 : 750 – 759 . [CSA] [CROSSREF]
- Weber , A. 1968 . The mechanism of the action of caffeine on sarcoplasmic reticulum . Gen. Physiol. , 52 : 760 – 772 . [CSA] [CROSSREF]
- Delay , M. , Ribalet , B. and Vergara , J. 1986 . Caffeine potentiation of calcium release in frog skeletal muscle fibers . J. Physiol. , 375 : 535 – 559 . [PUBMED] [INFOTRIEVE] [CSA]
- Weber , A. , Herz , R. and Reiss , I. 1964 . The regulation of myofibrillar activity by calcium . Proc. R. Soc. Lond. B Biol. Sci. , 160 : 489 – 499 . [PUBMED] [INFOTRIEVE] [CSA]
- Palade , P. , Dettbarn , C. , Brunder , D. , Stein , P. and Hals , G. 1989 . Pharmacology of calcium release from sarcoplasmic reticulum . J. Bioenerg. Biomembr , 21 : 295 – 320 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Frank , G. B. 1987 . Pharmacological studies of excitation-contraction coupling in skeletal muscle . Can. J. Physiol. Pharmacol. , 65 : 711 – 716 . [PUBMED] [INFOTRIEVE] [CSA]
- Hawke , T. J. , Allen , D. G. and Lindinger , M. I. 1998 . Paraxanthine increases [Ca2+]i in resting mouse skeletal muscle . FASEB J. , 12 : A1030 [CSA]
- Ebashi , S. 1991 . Excitation-contraction coupling and the mechanism of muscle contraction . Annu. Rev. Physiol. , 53 : 1 – 16 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Melzer , W. , Herrmann-Frank , A. and Luttgau , H. C. 1995 . The role of Ca2+ ions in excitation-contraction coupling of skeletal muscle fibers . Biochim. Biophys. Acta , 1241 : 59 – 116 . [PUBMED] [INFOTRIEVE] [CSA]
- Ferrier , G. R. and Howlett , S. E. 2001 . Cardiac excitation-contraction coupling: Role of membrane potential in regulation of contraction . Am. J. Physiol. Heart Circ. Physiol , 280 : H1928 – 1944 . [PUBMED] [INFOTRIEVE] [CSA]
- Lamb , G. D. 2000 . Excitation-contraction coupling in skeletal muscle: Comparisons with cardiac muscle . Clin. Exp. Pharmacol. Physiol. , 27 : 216 – 224 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Bers , D. M. 2002 . Cardiac excitation-contraction coupling . Nature , 415 : 198 – 205 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Meissner , G. and Lu , X. 1995 . Dihydropyridine receptor-ryanodine receptor interactions in skeletal muscle excitation-contraction coupling . Biosci. Rep. , 15 : 399 – 408 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Fosset , M. , Jaimovich , E. , Delpont , E. and Lazdunski , M. 1983 . [3H]nitrendipine receptors in skeletal muscle . J. Biol. Chem. , 258 : 6086 – 6092 . [PUBMED] [INFOTRIEVE] [CSA]
- Fleischer , S. , Ogunbunmi , E. M. , Dixon , M. C. and Fleer , E. A. 1985 . Localization of Ca2+ release channels with ryanodine in junctional terminal cisternae of sarcoplasmic reticulum of fast skeletal muscle . Proc. Natl. Acad. Sci. USA , 82 : 7256 – 7259 . [PUBMED] [INFOTRIEVE] [CSA]
- Pessah , I. N. , Francini , A. O. , Scales , D. J. , Waterhouse , A. L. and Casida , J. E. 1986 . Calcium-ryanodine receptor complex. Solubilization and partial characterization from skeletal muscle junctional sarcoplasmic reticulum vesicles . J. Biol. Chem. , 261 : 8643 – 8648 . [PUBMED] [INFOTRIEVE] [CSA]
- Ogawa , Y. , Kurebayashi , N. and Murayama , T. 1999 . Ryanodine receptor isoforms in excitation-contraction coupling . Adv. Biophys. , 36 : 27 – 64 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Fill , M. and Copello , J. A. 2002 . Ryanodine receptor calcium release channels . Physiol. Rev. , 82 : 893 – 922 . [PUBMED] [INFOTRIEVE] [CSA]
- Wagenknecht , T. and Radermacher , M. 1997 . Ryanodine receptors: Structure and macromolecular interactions . Curr. Opin. Struct. Biol. , 7 : 258 – 265 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Franzini-Armstrong , C. and Protasi , F. 1997 . Ryanodine receptors of striated muscles: A complex channel capable of multiple interactions . Physiol. Rev. , 77 : 699 – 729 . [PUBMED] [INFOTRIEVE] [CSA]
- Yano , K. and Zarain-Herzberg , A. 1994 . Sarcoplasmic reticulum calsequestrins: Structural and functional properties . Mol. Cell. Biochem. , 135 : 61 – 70 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Guo , W. , Jorgensen , A. O. and Campbell , K. P. 1996 . Triadin, a linker for calsequestrin and the ryanodine receptor . Soc. Gen. Physiol. Ser. , 51 : 19 – 28 . [PUBMED] [INFOTRIEVE] [CSA]
- Tang , W. , Sencer , S. and Hamilton , S. L. 2002 . Calmodulin modulation of proteins involved in excitation-contraction coupling . Front. Biosci. , 7 : D1583 – 1589 . [PUBMED] [INFOTRIEVE] [CSA]
- Marks , A. R. 1996 . Cellular functions of immunophilins . Physiol. Rev , 76 : 631 – 649 . [PUBMED] [INFOTRIEVE] [CSA]
- Ondrias , K. , Marx , S. O. , Gaburjakova , M. and Marks , A. R. 1998 . FKBP12 modulates gating of the ryanodine receptor/calcium release channel . Ann. N.Y. Acad. Sci. , 853 : 149 – 156 . [PUBMED] [INFOTRIEVE] [CSA]
- Marty , I. , Robert , M. , Villaz , M. , De Jongh , K. , Lai , Y. , Catterall , W. A. and Ronjat , M. 1994 . Biochemical evidence for a complex involving dihydropyridine receptor and ryanodine receptor in triad junctions of skeletal muscle . Proc. Natl. Acad. Sci. USA , 91 : 2270 – 2274 . [PUBMED] [INFOTRIEVE] [CSA]
- Endo , M. , Tanaka , M. and Ogawa , Y. 1970 . Calcium induced release of calcium from the sarcoplasmic reticulum of skinned skeletal muscle fibers . Nature , 228 : 34 – 36 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Endo , M. 1997 . Calcium release from the sarcoplasmic reticulum . Physiol. Rev. , 57 : 71 – 108 . [CSA]
- Schneider , M. F. and Chandler , W. K. 1973 . Voltage dependent charge movement of skeletal muscle: A possible step in excitation-contraction coupling . Nature , 242 : 244 – 246 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Rios , E. and Pizarro , G. 1991 . Voltage sensor of excitation-contraction coupling in skeletal muscle . Physiol. Rev. , 71 : 849 – 908 . [PUBMED] [INFOTRIEVE] [CSA]
- Farah , C. S. and Reinach , F. C. 1995 . The troponin complex and regulation of muscle contraction . FASEB J. , 9 : 755 – 767 . [PUBMED] [INFOTRIEVE] [CSA]
- Ohtsuki , I. 1999 . Calcium ion regulation of muscle contraction: The regulatory role of troponin T . Mol. Cell. Biochem. , 190 : 33 – 38 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Franzini-Armstrong , C. 1998 . Annemarie Weber: Ca2+ and the regulation of muscle contraction . Trends Cell Biol. , 8 : 251 – 253 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Niggli , E. 1999 . Localized intracellular calcium signaling in muscle: Calcium sparks and calcium quark . Annu. Rev. Physiol. , 61 : 311 – 335 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Meissner , G. 1994 . Ryanodine receptor/Ca2+ release channels and their regulation by endogenous effectors . Annu. Rev. Physiol. , 56 : 485 – 508 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Meissner , G. 2002 . Regulation of mammalian ryanodine receptors . Front. Biosci. , 7 : D2072 – 2080 . [PUBMED] [INFOTRIEVE] [CSA]
- Coronado , R. , Morrissette , J. , Sukhareva , M. and Vaughan , D. M. 1994 . Structure and function of ryanodine receptors . Am. J. Physiol. , 266 : C1485 – 1504 . [PUBMED] [INFOTRIEVE] [CSA]
- Xu , L. , Tripathy , A. , Pasek , D. A. and Meissner , G. 1998 . Potential for pharmacology of ryanodine receptor/calcium release channels . Ann. N. Y. Acad. Sci. , 853 : 130 – 148 . [PUBMED] [INFOTRIEVE] [CSA]
- Zucchi , R. and Ronca-Testoni , S. 1997 . The sarcoplasmic reticulum Ca2+ channel/ryanodine receptor: Modulation by endogenous effectors, drugs and disease states . Pharmacol Rev. , 49 : 1 – 51 . [PUBMED] [INFOTRIEVE] [CSA]
- Laver , D. R. , Baynes , T. M. and Dulhunty , A. F. 1997 . Magnesium inhibition of ryanodine-receptor calcium channels: Evidence for two independent mechanisms . J. Membr. Biol. , 156 : 213 – 229 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Rousseau , E. , Ladine , J. , Liu , Q. Y. and Meissner , G. 1998 . Activation of the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum by caffeine and related compounds . Arch. Biochem. Biophys. , 267 : 75 – 86 . [CSA] [CROSSREF]
- Rousseau , E. and Meissner , G. 1989 . Single cardiac sarcoplasmic reticulum Ca2+-release channel: Activation by caffeine . Am. J. Physiol. , 256 : H328 – 333 . [PUBMED] [INFOTRIEVE] [CSA]
- Palade , P. 1987 . Drug-induced Ca2+ release from isolated sarcoplasmic reticulum. I. Use of pyrophosphate to study caffeine-induced Ca2+ release . J. Biol. Chem. , 262 : 6135 – 6141 . [PUBMED] [INFOTRIEVE] [CSA]
- Murayama , T. , Kurebayashi , N. and Ogawa , Y. 2000 . Role of Mg2+ in Ca2+-induced Ca2+ release through ryanodine receptors of frog skeletal muscle: Modulations by adenine nucleotides and caffeine . Biophys. J. , 78 : 1810 – 1824 . [PUBMED] [INFOTRIEVE] [CSA]
- Herrmann-Frank , A. , Luttgau , H. C. and Stephenson , D. G. 1999 . Caffeine and excitation-contraction coupling in skeletal muscle: A stimulating story . J. Muscle Res. Cell Motil. , 20 : 223 – 237 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Salviati , G. and Volpe , P. 1988 . Ca2+ release from sarcoplasmic reticulum of skinned fast- and slow-twitch muscle fibers . Am. J. Physiol. , 254 : C459 – 465 . [PUBMED] [INFOTRIEVE] [CSA]
- Fryer , M. W. and Neering , I. R. 1989 . Actions of caffeine on fast- and slow-twitch muscles of the rat . J. Physiol. , 416 : 435 – 454 . [PUBMED] [INFOTRIEVE] [CSA]
- Ligeti , L. , Batkai , S. , Ivanics , T. , Toth , A. , Slaaf , D. W. and Reneman , R. S. 1998 . Caffeine induced free calcium changes in intact fast- and slow-twitch muscles . FASEB J. , 12 : A1030 [CSA]
- Mitsumoto , H. , DeBoer , G. E. , Bunge , G. , Andrish , J. T. , Tetzlaff , J. E. and Cruse , R. P. 1990 . Fiber-type specific caffeine sensitivities in normal human skinned muscle fibers . Anesthesiology , 72 : 50 – 54 . [PUBMED] [INFOTRIEVE] [CSA]
- Fryer , M. W. and Stephenson , D. G. 1996 . Total and sarcoplasmic reticulum calcium contents of skinned fibres from rat skeletal muscle . J. Physiol. , 493 : 357 – 370 . [PUBMED] [INFOTRIEVE] [CSA]
- Pagala , M. K. and Taylor , S. R. 1998 . Imaging caffeine-induced Ca2+ transients in individual fast-twitch and slow-twitch rat skeletal muscle fibers . Am. J. Physiol. , 274 : C623 – 632 . [PUBMED] [INFOTRIEVE] [CSA]
- Rossi , R. , Bottinelli , R. , Sorrentino , V. and Reggiani , C. 2001 . Response to caffeine and ryanodine receptor isoforms in mouse skeletal muscles . Am. J. Physiol Cell Physiol. , 281 : C585 – 594 . [PUBMED] [INFOTRIEVE] [CSA]
- Marco , L. A. and Nastuk , W. L. 1968 . Sarcomeric oscillations in frog skeletal muscle fibers . Science , 161 : 1357 – 1358 . [PUBMED] [INFOTRIEVE] [CSA]
- Klein , M. G. , Simon , B. J. and Schneider , M. F. 1992 . Effects of procaine and caffeine on calcium release from the sarcoplasmic reticulum in frog skeletal muscle . J. Physiol. , 453 : 341 – 366 . [PUBMED] [INFOTRIEVE] [CSA]
- Herrmann-Frank , A. 1989 . Caffeine- and Ca2+-induced mechanical oscillations in isolated skeletal muscle fibres of the frog . Muscle Res. Cell. Motil. , 10 : 437 – 445 . [CSA] [CROSSREF]
- Kumbaraci , N. M. and Nastuk , W. L. 1982 . Action of caffeine in excitation-contraction coupling of frog skeletal muscle fibers . J. Physiol. , 325 : 195 – 211 . [PUBMED] [INFOTRIEVE] [CSA]
- Herrmann-Frank , A. and Meissner , G. 1989 . Isolation of a Ca2+-releasing factor from caffeine-treated skeletal muscle fibres and its effect on Ca2+ release from sarcoplasmic reticulum . J. Muscle Res. Cell Motil. , 10 : 427 – 436 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Soderling , S. H. and Beavo , J. A. 2000 . Regulation of cAMP and cGMP signaling: New phosphodiesterases and new functions . Curr. Opin. Cell. Biol. , 12 : 174 – 179 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Fawcett , L. , Baxendale , R. , Stacey , P. , McGrouther , C. , Harrow , L. , Soderling , S. , Hetman , J. , Beavo , J. A. and Phillips , S. C. 2000 . Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11 A . Proc. Natl. Acad. Sci. USA , 97 : 3702 – 3707 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Beavo , J. A. 1995 . Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms . Physiol. Rev. , 75 : 725 – 748 . [PUBMED] [INFOTRIEVE] [CSA]
- Conti , M. , Nemoz , G. , Sette , C. and Vicini , E. 1995 . Recent progress in understanding the hormonal regulation of phosphodiesterases . Endocr. Rev. , 16 : 370 – 389 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Butcher , R. W. and Sutherland , E. W. 1962 . Adenosine 3′,5′-phosphate in biological materials. I. Purification and properties of cyclic 3′,5′-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine 3′,5′-phosphate in human urine . J. Biol. Chem. , 237 : 1244 – 1250 . [PUBMED] [INFOTRIEVE] [CSA]
- Weishaar , R. E. , Cain , M. H. and Bristol , J. A. 1985 . A new generation of phosphodiesterase inhibitors: Multiple molecular forms of phosphodiesterase and the potential for drug selectivity . J. Med. Chem. , 28 : 537 – 545 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Exton , J. H. , Robison , G. A. , Sutherland , E. W. and Park , C. R. 1971 . Studies on the role of adenosine 3′,5′-monophosphate in the hepatic actions of glucagon and catecholamines . J. Biol. Chem. , 246 : 6166 – 6177 . [PUBMED] [INFOTRIEVE] [CSA]
- Sutherland , E. W. 1972 . Studies on the mechanism of hormone action . Science , 177 : 401 – 408 . [PUBMED] [INFOTRIEVE] [CSA]
- Fain , J. N. , Pointer , R. H. and Ward , W. F. 1972 . Effects of adenosine nucleosides on adenylate cyclase, phosphodiesterase, cyclic adenosine monophosphate accumulation, and lipolysis in fat cells . J. Biol. Chem. , 247 : 6866 – 6872 . [PUBMED] [INFOTRIEVE] [CSA]
- Butcher , R. W. 1970 . The role of cyclic AMP in the actions of some lipolytic and anti-lipolytic agents . Horm. Metab. Res. , 2 : 5 – 10 . [PUBMED] [INFOTRIEVE] [CSA]
- Hynie , S. , Krishna , G. and Brodie , B. B. 1966 . Theophylline as a tool in studies of the role of cyclic adenosine 3′,5′-monophosphate in hormone-induced lipolysis . J. Pharmacol. Exp. Ther. , 153 : 90 – 96 . [PUBMED] [INFOTRIEVE] [CSA]
- Beavo , J. A. , Rogers , N. L. , Crofford , O. B. , Hardman , J. G. , Sutherland , E. W. and Newman , E. V. 1970 . Effects of xanthine derivatives on lipolysis and on adenosine 3′,5′-monophosphate phosphodiesterase activity . Mol. Pharmacol. , 6 : 597 – 603 . [PUBMED] [INFOTRIEVE] [CSA]
- Ingebretsen , C. , Clark , J. F. , Allen , D. O. and Ashmore , J. 1974 . Effect of glucagon, dibutyryl adenosine 3′,5′-cyclic monophosphate and phosphodiesterase inhibitors on rat liver phosphorylase activity and adenosine 3′,5′-cyclic monophosphate levels . Biochem. Pharmacol. , 23 : 2139 – 2146 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Smellie , F. W. , Davis , C. W. , Daly , J. W. and Wells , J. N. 1979 . Alkylxanthines: Inhibition of adenosine-elicited accumulation of cyclic AMP in brain slices and of brain phosphodiesterase activity . Life Sci. , 24 : 2475 – 2482 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Fredholm , B. B. , Hedqvist , P. and Vernet , L. 1978 . Effect of theophylline and other drugs on rabbit renal cyclic nucleotide phosphodiesterase, 5′-nucleotidase, and adenosine deaminase . Biochem. Pharmacol. , 27 : 2845 – 2850 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Glass , W. F. 2nd and and Moore , J. B. Jr. 1979 . Inhibition of human lung cyclic GMP and cyclic AMP phosphodiesterases by certain nucleosides, nucleotides, and pharmacological phosphodiesterase inhibitors . Biochem. Pharmacol. , 28 : 1107 – 1112 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Green , D. , Guy , G. and Moore , J. B. Jr. 1977 . The adenosine 3′,5′-monophosphate and guanosine 3′,5′-monophosphate phosphodiesterases from human lung tissue . Life Sci. , 20 : 1157 – 1162 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Macphee , C. H. , Harrison , S. A. and Beavo , J. A. 1986 . Immunological identification of the major platelet low-Km cAMP phosphodiesterase: Probable target for anti-thrombotic agents . Proc. Natl. Acad. Sci. USA , 83 : 6660 – 6663 . [PUBMED] [INFOTRIEVE] [CSA]
- Nemecek , G. M. , Wells , J. N. and Butcher , R. W. 1980 . Inhibition of fibroblast cyclic AMP escape and cyclic nucleotide phosphodiesterase activities by xanthines . Mol. Pharmacol. , 18 : 57 – 64 . [PUBMED] [INFOTRIEVE] [CSA]
- Kramer , G. L. and Wells , J. N. 1980 . Xanthines and skeletal muscle: Lack of relationship between phosphodiesterase inhibition and increased twitch tension in rat diaphragms . Mol. Pharmacol. , 17 : 73 – 78 . [PUBMED] [INFOTRIEVE] [CSA]
- Wells , J. N. , Wu , Y. J. , Baird , C. E. and Hardman , J. G. 1975 . Phosphodiesterases from porcine coronary arteries: Inhibition of separated forms by xanthines, papaverine, and cyclic nucleotides . Mol. Pharmacol. , 11 : 775 – 783 . [PUBMED] [INFOTRIEVE] [CSA]
- Goodsell , E. B. , Stein , H. H. and Wenzke , K. J. 1971 . 8-substituted theophyllines. In vitro inhibition of 3′,5′-cyclic adenosine monophosphate phosphodiesterase and pharmacological spectrum in mice . J. Med. Chem. , 14 : 1202 – 1205 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Weishaar , R. E. , Quade , M. M. , Schenden , J. A. and Evans , D. B. 1985 . Relationship between inhibition of cardiac muscle phosphodiesterases, changes in cyclic nucleotide levels, and contractile response for CI-914 and other novel cardiotonics . J. Cyclic Nucleotide Protein Phosphor. Res. , 10 : 551 – 564 . [PUBMED] [INFOTRIEVE] [CSA]
- Chebotareva , N. A. , Klinov , S. V. and Kurganov , B. I. 2001 . Regulation of muscle glycogen phosphorylase by physiological effectors . Biotechnol. Genet. Eng. Rev. , 18 : 265 – 297 . [PUBMED] [INFOTRIEVE] [CSA]
- Buchbinder , J. L. , Rath , V. L. and Fletterick , R. J. 2001 . Structural relationships among regulated and unregulated phosphorylases . Annu. Rev. Biophys. Biomol. Struct. , 30 : 191 – 209 . [PUBMED] [INFOTRIEVE] [CSA]
- Johnson , L. N. 1992 . Glycogen phosphorylase: Control by phosphorylation and allosteric effectors . FASEB J. , 6 : 2274 – 2282 . [PUBMED] [INFOTRIEVE] [CSA]
- Johnson , L. N. and Barford , D. 1990 . Glycogen phosphorylase. The structural basis of the allosteric response and comparison with other allosteric proteins . J. Biol. Chem. , 265 : 2409 – 2412 . [PUBMED] [INFOTRIEVE] [CSA]
- Fletterick , R. J. and Madsen , N. B. 1980 . The structures and related functions of phosphorylase a . Annu. Rev. Biochem. , 49 : 31 – 61 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Cohen , P. 1983 . Protein phosphorylation and the control of glycogen metabolism in skeletal muscle . Philos. Trans. R. Soc. Lond. B Biol. Sci. , 302 : 13 – 25 . [PUBMED] [INFOTRIEVE] [CSA]
- Kihlman , B. and Overgaard–Hansen , K. 1955 . Inhibition of muscle phosphorylase by methylated oxypurines . Exp. Cell Res. , 8 : 252 – 255 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Kasvinsky , P. J. , Shechosky , S. and Fletterick , R. J. 1978 . Synergistic regulation of phosphorylase a by glucose and caffeine . J. Biol. Chem. , 253 : 9102 – 9106 . [PUBMED] [INFOTRIEVE] [CSA]
- Kobayashi , M. , Soman , G. and Graves , D. J. 1982 . A comparison of the activator sites of liver and muscle glycogen phosphorylase b . J. Biol. Chem. , 257 : 14041 – 14047 . [PUBMED] [INFOTRIEVE] [CSA]
- Madsen , N. B. , Shechosky , S. and Fletterick , R. J. 1983 . Site-site interactions in glycogen phosphorylase b probed by ligands specific for each site . Biochemistry , 22 : 4460 – 4465 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Kasvinsky , P. J. , Madsen , N. B. , Sygusch , J. and Fletterick , R. J. 1978 . The regulation of glycogen phosphorylase a by nucleotide derivatives. Kinetic and x-ray crystallographic studies . J. Biol. Chem. , 253 : 3343 – 3351 . [PUBMED] [INFOTRIEVE] [CSA]
- Tsitsanou , K. E. , Skamnaki , V. T. and Oikonomakos , N. G. 2000 . Structural basis of the synergistic inhibition of glycogen phosphorylase a by caffeine and a potential antidiabetic drug . Arch. Biochem. Biophys. , 384 : 245 – 254 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Martin , W. H. , Hoover , D. J. , Armento , S. J. , Stock , I. A. , McPherson , R. K. , Danley , D. E. , Stevenson , R. W. , Barrett , E. J. and Treadway , J. L. 1998 . Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose . in vivo. Proc. Natl. Acad. Sci. USA , 95 : 1776 – 1781 . [CSA] [CROSSREF]
- Bot , G. , Kovacs , E. and Gergely , P. 1977 . Role of tetramer in equilibrium dimer equilibrium in the dephosphorylation and activity of phosphorylase a . Acta Biochim. Biophys. Acad. Sci. Hung. , 12 : 335 – 341 . [PUBMED] [INFOTRIEVE] [CSA]
- Hajdu , J. , Dombradi , V. , Bot , G. and Friedrich , P. 1979 . Structural changes in glycogen phosphorlase as revealed by cross-linking with bifunctional diimidates: Phosphorylase b . Biochemistry , 18 : 4037 – 4041 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Withers , S. G. , Sykes , B. D. , Madsen , N. B. and Kasvinsky , P. J. 1979 . Identical structural changes induced in glycogen phosphorylase by two nonexclusive allosteric inhibitors . Biochemistry , 18 : 5342 – 5348 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Steiner , R. F. , Greer , L. , Bhat , R. and Oton , J. 1980 . Structural changes induced in glycogen phosphorylase b by the binding of glucose and caffeine . Biochim. Biophys. Acta , 611 : 269 – 279 . [PUBMED] [INFOTRIEVE] [CSA]
- Ercan-Fang , N. and Nuttall , F. Q. 1997 . The effect of caffeine and caffeine analogs on rat liver phosphorylase a activity . J. Pharmacol. Exp. Ther. , 280 : 1312 – 1318 . [PUBMED] [INFOTRIEVE] [CSA]
- Kasvinsky , P. J. 1982 . The effect of AMP on inhibition of muscle phosphorylase a by glucose derivatives . J. Biol. Chem. , 257 : 10805 – 10810 . [PUBMED] [INFOTRIEVE] [CSA]
- Leonidas , D. D. , Oikonomakos , N. G. , Papageorgiou , A. C. , Xenakis , A. , Cazianis , C. T. and Bern , F. 1990 . The ammonium sulfate activation of phosphorylase b . FEBS Lett. , 261 : 23 – 27 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Helmreich , E. , Michaelides , M. C. and Cori , C. F. 1967 . Effects of substrates and a substrate analog on the binding of 5′-adenylic acid to muscle phosphorylase a . Biochemistry , 6 : 3695 – 3710 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Barford , D. and Johnson , L. N. 1989 . The allosteric transition of glycogen phosphorylase . Nature , 340 : 609 – 616 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Barford , D. , Hu , S. H. and Johnson , L. N. 1991 . Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP . J. Mol. Biol. , 218 : 233 – 260 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Kasvinsky , P. J. , Fletterick , R. J. and Madsen , N. B. 1981 . Regulation of the dephosphorylation of glycogen phosphorylase a and synthase b by glucose and caffeine in isolated hepatocytes . Can. J. Biochem. , 59 : 387 – 395 . [PUBMED] [INFOTRIEVE] [CSA]
- Gilboe , D. P. and Nuttall , F. Q. 1982 . Stimulation of liver glycogen particle synthase D phosphatase activity by caffeine, AMP, and glucose 6-phosphate . Arch. Biochem. Biophys. , 219 : 179 – 185 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Gilboe , D. P. and Nuttall , F. Q. 1984 . Direct glucose stimulation of glycogen synthase phosphatase activity in a liver glycogen particle preparation . Arch. Biochem. Biophys. , 228 : 587 – 591 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Gilboe , D. P. and Nuttall , F. Q. 1984 . The synergistic action of caffeine or adenosine on glucose stimulation of liver glycogen synthase phosphatase activity . FEBS Lett. , 170 : 365 – 369 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Gilboe , D. P. 1986 . The mechanism of caffeine-enhanced glucose stimulation of liver glycogen synthase phosphatase activity . Biochem. Pharmacol. , 35 : 2097 – 2105 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Rush , J. W. and Spriet , L. L. 2001 . Skeletal muscle glycogen phosphorylase a kinetics: Effects of adenine nucleotides and caffeine . J. Appl. Physiol. , 91 : 2071 – 2078 . [PUBMED] [INFOTRIEVE] [CSA]
- Hynie , S. and Wenke , M. 1995 . The absence of stimulation of lipolysis by papaverine, a strong inhibitor of phosphodiesterase . Eur. J. Pharmacol. , 30 : 230 – 237 . [CSA] [CROSSREF]
- Kather , H. and Scheurer , A. 1987 . Effects of different phosphodiesterase inhibitors on the antilipolytic action of insulin in human adipocytes . Horm. Metab. Res. , 19 : 379 – 381 . [PUBMED] [INFOTRIEVE] [CSA]
- Persson , C. G. , Andersson , K. E. and Kjellin , G. 1986 . Effects of enprofylline and theophylline may show the role of adenosine . Life Sci. , 38 : 1057 – 1072 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Londos , C. , Cooper , D. M. , Schlegel , W. and Rodbell , M. 1978 . Adenosine analogs inhibit adipocyte adenylate cyclase by a GTP-dependent process: Basis for actions of adenosine and methylxanthines on cyclic AMP production and lipolysis . Proc. Natl. Acad. Sci. USA , 75 : 5362 – 5366 . [PUBMED] [INFOTRIEVE] [CSA]
- Fain , J. N. and Wieser , P. B. 1975 . Effects of adenosine deaminase on cyclic adenosine monophosphate accumulation, lipolysis, and glucose metabolism of fat cells . J. Biol. Chem. , 250 : 1027 – 1034 . [PUBMED] [INFOTRIEVE] [CSA]
- Choi , O. H. , Shamim , M. T. , Padgett , W. L. and Daly , J. W. 1988 . Caffeine and theophylline analogues: Correlation of behavioral effects with activity as adenosine receptor antagonists and as phosphodiesterase inhibitors . Life Sci. , 43 : 387 – 398 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Fredholm , B. B. and Persson , C. G. 1982 . Xanthine derivatives as adenosine receptor antagonists . Eur. J. Pharmacol. , 81 : 673 – 676 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Londos , C. , Cooper , D. M. and Wolff , J. 1980 . Subclasses of external adenosine receptors . Proc. Natl. Acad. Sci. USA , 77 : 2551 – 2554 . [PUBMED] [INFOTRIEVE] [CSA]
- Fredholm , B. B. 1980 . Are methylxanthine effects due to antagonism of endogenous adenosine? . Trends Pharmacol. Sci. , 1 : 129 – 132 . [CSA] [CROSSREF]
- Fredholm , B. B. 1995 . Astra Award Lecture. Adenosine, adenosine receptors, and the actions of caffeine . Pharmacol. Toxicol. , 76 : 93 – 101 . [PUBMED] [INFOTRIEVE] [CSA]
- Rall , T. W. 1982 . The 1982 Theodore Weicker Memorial Award Oration: Evolution of the mechanism of action of methylxanthines: From calcium mobilizers to antagonists of adenosine receptors . Pharmacologist , 24 : 277 – 287 . [CSA]
- Sattin , A. and Rall , T. W. 1970 . The effect of adenosine and adenine nucleotides on the cyclic adenosine 3′,5′-phosphate content of guinea pig cerebral cortex slices . Mol. Pharmacol. , 6 : 13 – 23 . [PUBMED] [INFOTRIEVE] [CSA]
- Snyder , S. H. , Katims , J. J. , Annau , Z. , Bruns , R. F. and Daly , J. W. 1981 . Adenosine receptors and behavioral actions of methylxanthines . Proc. Natl. Acad. Sci. USA , 78 : 3260 – 3264 . [PUBMED] [INFOTRIEVE] [CSA]
- Daly , J. W. , Bruns , R. F. and Snyder , S. H. 1981 . Adenosine receptors in the central nervous system: Relationship to the central actions of methylxanthines . Life Sci. , 28 : 2083 – 2097 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Daly , J. W. 1982 . Adenosine receptors: Targets for future drugs . J. Med. Chem. , 25 : 197 – 207 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Ukena , D. , Schudt , C. and Sybrecht , G. W. 1993 . Adenosine receptor-blocking xanthines as inhibitors of phosphodiesterase isozymes . Biochem. Pharmacol. , 45 : 847 – 851 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Daly , J. W. , Padgett , W. L. and Shamim , M. T. 1986 . Analogues of caffeine and theophylline: Effect of structural alterations on affinity at adenosine receptors . J. Med. Chem. , 29 : 1305 – 1308 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Schwabe , U. , Ukena , D. and Lohse , M. J. 1985 . Xanthine derivatives as antagonists at A1 and A2 adenosine receptors . Naunyn. Schmiedebergs Arch. Pharmacol. , 330 : 212 – 221 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Fredholm , B. B. , Irenius , E. , Kull , B. and Schulte , G. 2001 . Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cells . Biochem. Pharmacol. , 61 : 443 – 448 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Fredholm , B. B. , Arslan , G. , Halldner , L. , Kull , B. , Schulte , G. and Wasserman , W. 2000 . Structure and function of adenosine receptors and their genes . Naunyn. Schmiedebergs Arch. Pharmacol. , 362 : 364 – 374 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Fredholm , B. B. , Ijzerman , A. P. , Jacobson , K. A. , Klotz , K. N. and Linden , J. 2001 . International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors . Pharmacol. Rev. , 53 : 527 – 552 . [PUBMED] [INFOTRIEVE] [CSA]
- Ralevic , V. and Burnstock , G. 1998 . Receptors for purines and pyrimidines . Pharmacol. Rev. , 50 : 413 – 492 . [PUBMED] [INFOTRIEVE] [CSA]
- Olah , M. E. and Stiles , G. L. 1995 . Adenosine receptor subtypes: Characterization and therapeutic regulation . Annu. Rev. Pharmacol. Toxicol. , 35 : 581 – 606 . [PUBMED] [INFOTRIEVE] [CSA]
- Fredholm , B. B. 1995 . Adenosine receptors in the central nervous system . News Physiol. Sci. , 10 : 122 – 128 . [CSA]
- Palmer , T. M. and Stiles , G. L. 1995 . Adenosine receptors . Neuropharmacology , 34 : 683 – 694 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Feoktistov , I. and Biaggioni , I. 1997 . Adenosine A2B receptors . Pharmacol. Rev. , 49 : 381 – 402 . [PUBMED] [INFOTRIEVE] [CSA]
- North , R. A. and Barnard , E. A. 1997 . Nucleotide receptors . Curr. Opin. Neurobiol. , 7 : 346 – 357 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Shryock , J. C. and Belardinelli , L. 1997 . Adenosine and adenosine receptors in the cardiovascular system: Biochemistry, physiology, and pharmacology . Am. J. Cardiol. , 79 : 2 – 10 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Auchampach , J. A. and Bolli , R. 1999 . Adenosine receptor subtypes in the heart: Therapeutic opportunities and challenges . Am. J. Physiol. , 276 : H1113 – 1116 . [PUBMED] [INFOTRIEVE] [CSA]
- Svenningsson , P. , Le Moine , C. , Fisone , G. and Fredholm , B. B. 1999 . Distribution, biochemistry and function of striatal adenosine A2A receptors . Prog. Neurobiol. , 59 : 355 – 396 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Baraldi , P. G. , Cacciari , B. , Romagnoli , R. , Merighi , S. , Varani , K. , Borea , P. A. and Spalluto , G. 2000 . A3 adenosine receptor ligands: History and perspectives . Med. Res. Rev. , 20 : 103 – 128 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Klotz , K. N. 2000 . Adenosine receptors and their ligands . Naunyn. Schmiedebergs Arch. Pharmacol. , 362 : 382 – 391 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Jorgensen , P. L. , Hakansson , K. O. and Karlish , S. J. 2003 . Structure and mechanism of Na,K-ATPase: Functional sites and their interactions . Annu. Rev. Physiol. , 65 : 817 – 849 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Kaplan , J. H. 2002 . Biochemistry of Na,K-ATPase . Annu. Rev. Biochem. , 71 : 511 – 535 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Kaplan , J. H. , Hu , Y. K. and Gatto , C. 2001 . Conformational coupling: The moving parts of an ion pump . J. Bioenerg. Biomembr. , 33 : 379 – 385 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Renaud , J. M. 2002 . Modulation of force development by Na+, K+, Na+ K+ pump, and KATP channel during muscular activity . Can. J. Appl. Physiol. , 27 : 296 – 315 . [PUBMED] [INFOTRIEVE] [CSA]
- Tong , E. Y. , Bittar , E. E. , Chen , S. S. and Danielson , B. G. 1972 . The influence of caffeine on the sodium efflux in barnacle muscle fibers . Experientia , 28 : 1031 – 1033 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Bittar , E. E. , Hift , H. , Huddart , H. and Tong , E. 1974 . The effects of caffeine on sodium transport, membrane potential, mechanical tension and ultrastructure in barnacle muscle fibres . J. Physiol. , 242 : 1 – 34 . [PUBMED] [INFOTRIEVE] [CSA]
- Hays , E. T. , Horowicz , P. and Swift , J. G. 1977 . Theophylline action on sodium fluxes in frog striated muscle . J. Pharmacol. Exp. Ther. , 202 : 388 – 396 . [PUBMED] [INFOTRIEVE] [CSA]
- Willmets , R. G. , Welsh , D. G. and Lindinger , M. I. 1994 . Paraxanthine stimulates 42K uptake in resting rat skeletal muscle . Med. Sci. Sports Exerc. , 26 : 853 [CSA]
- Lindinger , M. I. , Welsh , D. G. and Willmets , R. G. 1995 . Dose dependence of paraxanthine (PX) stimulation of skeletal muscle Na, K-pump activity . Physiol. Zool. , 68 : 185 [CSA]
- Hawke , T. J. , Willmets , R. G. and Lindinger , M. I. 1999 . K+ transport in resting rat hind- limb skeletal muscle in response to paraxanthine, a caffeine metabolite . Can. J. Physiol. Pharmacol. , 77 : 835 – 843 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Lindinger , M. I. , Willmets , R. G. and Hawke , T. J. 1996 . Stimulation of Na+, K+-pump activity in skeletal muscle by methylxanthines: Evidence and proposed mechanisms . Acta Physiol. Scand. , 156 : 347 – 353 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Gupta , M. P. , Makino , N. , Takeo , S. , Kaneko , M. and Dhalla , N. S. 1990 . Cardiac sarcolemma as a possible site of action of caffeine in rat heart . J. Pharmacol. Exp. Ther. , 255 : 1188 – 1194 . [PUBMED] [INFOTRIEVE] [CSA]
- Kotsias , B. A. and Venosa , R. A. 2001 . Caffeine-induced depolarization in amphibian skeletal muscle fibres: Role of Na+/Ca2+ exchange and K+ release . Acta Physiol. Scand. , 171 : 459 – 466 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Overduin , M. , Cheever , M. L. and Kutateladze , T. G. 2001 . Signaling with phosphoinositides: Better than binary . Mol. Interv. , 1 : 150 – 159 . [PUBMED] [INFOTRIEVE] [CSA]
- Toker , A. 2002 . Phosphoinositides and signal transduction . Cell. Mol. Life Sci. , 59 : 761 – 779 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Czech , M. P. 2003 . Dynamics of phosphoinositides in membrane retrieval and insertion . Annu. Rev. Physiol. , 65 : 791 – 815 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Leslie , N. R. , Biondi , R. M. and Alessi , D. R. 2001 . Phosphoinositide-regulated kinases andphosphoinositide phosphatases . Chem. Rev. , 101 : 2365 – 2380 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Vanhaesebroeck , B. , Leevers , S. J. , Panayotou , G. and Waterfield , M. D. 1997 . Phosphoinositide 3-kinases: A conserved family of signal transducers . Trends Biochem. Sci. , 22 : 267 – 272 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Toker , A. 2000 . Protein kinases as mediators of phosphoinositide 3-kinase signaling . Mol. Pharmacol. , 57 : 652 – 658 . [PUBMED] [INFOTRIEVE] [CSA]
- Vanhaesebroeck , B. and Waterfield , M. D. 1999 . Signaling by distinct classes of phosphoinositide 3-kinases . Exp. Cell Res. , 253 : 239 – 254 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Lam , K. , Carpenter , C. L. , Ruderman , N. B. , Friel , J. C. and Kelly , K. L. 1994 . The phosphatidylinositol 3-kinase serine kinase phosphorylates IRS-1. Stimulation by insulin and inhibition by wortmannin . J. Biol. Chem. , 269 : 20648 – 20652 . [PUBMED] [INFOTRIEVE] [CSA]
- Carpenter , C. L. , Auger , K. R. , Duckworth , B. C. , Hou , W. M. , Schaffhausen , B. and Cantley , L. C. 1993 . A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity . Mol. Cell. Biol. , 13 : 1657 – 1665 . [PUBMED] [INFOTRIEVE] [CSA]
- Toker , A. and Cantley , L. C. 1997 . Signalling through the lipid products of phosphoinositide-3-OH kinase . Nature , 387 : 673 – 676 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Honeyman , T. W. , Strohsnitter , W. , Scheid , C. R. and Schimmel , R. J. 1983 . Phosphatidic acid and phosphatidylinositol labelling in adipose tissue. Relationship to the metabolic effects of insulin and insulin-like agents . Biochem. J. , 212 : 489 – 498 . [PUBMED] [INFOTRIEVE] [CSA]
- Buckley , J. T. 1977 . Properties of human erythrocyte phosphatidylinositol kinase and inhibition by adenosine, ADP, and related compounds . Biochim. Biophys. Acta , 498 : 1 – 9 . [PUBMED] [INFOTRIEVE] [CSA]
- Sarkaria , J. N. , Busby , E. C. , Tibbetts , R. S. , Roos , P. , Taya , Y. , Karnitz , L. M. and Abraham , R. T. 1999 . Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine . Cancer Res. , 59 : 4375 – 4382 . [PUBMED] [INFOTRIEVE] [CSA]
- Blasina , A. , Price , B. D. , Turenne , G. A. and McGowan , C. H. 1999 . Caffeine inhibits the checkpoint kinase ATM . Curr. Biol. , 9 : 1135 – 1138 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Foukas , L. C. , Daniele , N. , Ktori , C. , Anderson , K. E. , Jensen , J. and Shepherd , P. R. 2002 . Direct effects of caffeine and theophylline on p 110 delta and other phosphoinositide 3-kinases. Differential effects on lipid kinase and protein kinase activities . J. Biol. Chem. , 277 : 37124 – 37130 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Shepherd , P. R. , Withers , D. J. and Siddle , K. 1998 . Phosphoinositide 3-kinase: The key switch mechanism in insulin signalling . Biochem. J. , 333 : 471 – 490 . [PUBMED] [INFOTRIEVE] [CSA]
- Sun , J. H. and Zhu , P. H. 1998 . Effects of high potassium and caffeine exposure on activities of Ca2+-dependent and Ca2+-independent protein kinase C in frog skeletal muscle . Cell. Signal. , 10 : 569 – 574 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Takasuga , S. , Katada , T. , Ui , M. and Hazeki , O. 1999 . Enhancement by adenosine of insulin-induced activation of phosphoinositide 3-kinase and protein kinase B in rat adipocytes . J. Biol. Chem. , 274 : 19545 – 19550 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Burke , G. , Chang , L. L. and Szabo , M. 1973 . Thyrotropin and cyclic nucleotide effects on prostaglandin levels in isolated thyroid cells . Science , 180 : 872 – 875 . [PUBMED] [INFOTRIEVE] [CSA]
- Dorrington , J. H. and Kilpatrick , R. 1967 . Effect of adenosine 3′,5′-(cyclic)-monophosphate on the synthesis of progestational steroids by rabbit ovarian tissue in vitro . Biochem. J. , 104 : 725 – 730 . [PUBMED] [INFOTRIEVE] [CSA]
- Wicks , W. D. 1968 . Tyrosine-alpha-ketoglutarate transaminase: Induction by epinephrine and adenosine-3′,5′-cyclic phosphate . Science , 160 : 997 – 998 . [PUBMED] [INFOTRIEVE] [CSA]
- Capovilla , M. , Cervetto , L. and Torre , V. 1982 . Antagonism between steady light and phosphodiesterase inhibitors on the kinetics of rod photoresponses . Proc. Natl. Acad. Sci. USA , 79 : 6698 – 6702 . [PUBMED] [INFOTRIEVE] [CSA]
- Sutherland , E. , Robinson , G. and Butcher , R. 1968 . Some aspects of the biological role of adenosine 3′,5′-monophosphate (cyclic AMP) . Circulation , 37 : 279 – 306 . [CSA]
- Tsuzuki , J. and Newburgh , R. W. 1975 . Inhibition of 5′-nucleotidase in rat brain by methylxanthines . J. Neurochem. , 25 : 895 – 896 . [PUBMED] [INFOTRIEVE] [CSA]
- Heyliger , C. E. , Panagia , V. and Dhalla , N. S. 1981 . Effect of cyclic AMP phosphodiesterase inhibitors on cardiac sarcolemmal 5′-nucleotidase . J. Pharmacol. Exp. Ther. , 217 : 489 – 493 . [PUBMED] [INFOTRIEVE] [CSA]
- Fredholm , B. B. and Lindgren , E. 1983 . Inhibition of soluble 5′-nucleotidase from rat brain by different xanthine derivatives . Biochem. Pharmacol. , 32 : 2832 – 2834 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Wharton , W. and Goz , B. 1979 . Induction of alkaline phosphatase activity in HeLa cells. Inhibition by xanthine derivatives and thermostability studies . Biochem. Pharmacol. , 28 : 763 – 768 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Manchester , K. L. , Bullock , G. and Roetzscher , V. M. 1973 . Influence of methylxanthines and local anaesthetics on the metabolism of muscle and associated changes in mitochondrial morphology . Chem.-Biol. Interact. , 6 : 273 – 296 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Manchester , K. L. 1970 . Toxicity of methylxanthines and local anaesthetics towards muscle . Biochem. J. , 117 : 39P – 40P . [PUBMED] [INFOTRIEVE] [CSA]
- Gluud , C. N. and Dich , J. 1977 . Inhibitory effect of xanthines on the incorporation of [14C]valine into proteins and on the secretion of albumin in isolated parenchymal rat liver cells . Biochem. Pharmacol. , 26 : 553 – 554 . [PUBMED] [INFOTRIEVE] [CSA]
- Halkerston , I. D. , Feinstein , M. and Hechter , O. 1966 . An anomalous effect of theophylline on ACTH and adenosine 3′,5′-monophosphate stimulation . Proc. Soc. Exp. Biol. Med. , 122 : 896 – 900 . [PUBMED] [INFOTRIEVE] [CSA]
- Raghupathy , E. , Peterson , N. A. and McKean , C. M. 1971 . Stimulatory effects on aminophylline on amino acid incorporation into protein by cell-free systems . Biochem. Pharmacol. , 20 : 1901 – 1915 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Lissitzky , S. , Mante , S. , Attali , J. C. and Cartouzou , G. 1969 . Action of 3′,5′-cyclic adenosinemonophosphate on the protein synthesizing capacity of thyroid polyribosomes in vitro . Biochem. Biophys. Res. Commun. , 35 : 437 – 443 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Khairallah , E. A. and Pitot , H. C. 1967 . 3′,5′-Cyclic AMP and the release of polysome- bound proteins in vitro . Biochem. Biophys. Res. Commun. , 29 : 269 – 273 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Fernandez-Puentes , C. , Carrasco , L. and Vazquez , D. 1974 . The enhancement of polypeptide synthesis in mammalian systems by methylxanthines . FEBS Lett. , 45 : 132 – 135 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Rumsby , P. C. , Kato , H. , Waldren , C. A. and Patterson , D. 1982 . Effects of caffeine on pyrimidine biosynthesis and 5-phosphoribosyl 1-pyrophosphate metabolism in Chinese hamster cell . J. Biol. Chem. , 257 : 11364 – 11367 . [PUBMED] [INFOTRIEVE] [CSA]
- Persson , C. G. , Karlsson , J. A. and Erjefalt , I. 1982 . Differentiation between bronchodilation and universal adenosine antagonism among xanthine derivatives . Life Sci. , 30 : 2181 – 2189 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Liu , W. and Meissner , G. 1997 . Structure-activity relationship of xanthines and skeletal muscle ryanodine receptor/Ca2+ release channel . Pharmacology , 54 : 135 – 143 . [PUBMED] [INFOTRIEVE] [CSA]
- Bruns , R. F. 1981 . Adenosine antagonism by purines, pteridines and benzopteridines in human fibroblasts . Biochem. Pharmacol. , 30 : 325 – 333 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Weinberger , M. and Hendeles , L. 1996 . Theophylline in asthma . N. Engl. J. Med. , 334 : 1380 – 1388 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Fulceri , R. , Nori , A. , Gamberucci , A. , Volpe , P. , Giunti , R. and Benedetti , A. 1994 . Fatty acyl-CoA esters induce calcium release from terminal cisternae of skeletal muscle . Cell Calcium , 15 : 109 – 116 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Oba , T. , Koshita , M. and Yamaguchi , M. 1997 . Ethanol enhances caffeine-induced Ca2+- release channel activation in skeletal muscle sarcoplasmic reticulum . Am. J. Physiol. , 272 : C622 – 627 . [PUBMED] [INFOTRIEVE] [CSA]
- Lee , H. C. 1993 . Potentiation of calcium- and caffeine-induced calcium release by cyclic ADP-ribose . J. Biol. Chem. , 268 : 293 – 299 . [PUBMED] [INFOTRIEVE] [CSA]
- Wendt , I. R. and Stephenson , D. G. 1983 . Effects of caffeine on Ca-activated force production in skinned cardiac and skeletal muscle fibres of the rat . Pflugers Arch. , 398 : 210 – 216 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Connett , R. J. , Ugol , L. M. , Hammack , M. J. and Hays , E. T. 1983 . Twitch potentiation and caffeine contractures in isolated rat soleus muscle . Comp. Biochem. Physiol. C. , 74 : 349 – 354 . [PUBMED] [INFOTRIEVE] [CSA] [CROSSREF]
- Block , B. M. , Barry , S. R. and Faulkner , J. A. 1992 . Aminophylline increases submaximum power but not intrinsic velocity of shortening of frog muscle . J. Appl. Physiol. , 73 : 71 – 74 . [PUBMED] [INFOTRIEVE] [CSA]
- O'Neill , S. C. , Donoso , P. and Eisner , D. A. 1990 . The role of [Ca2+]i and [Ca2+] sensitization in the caffeine contracture of rat myocytes: Measurement of [Ca2+]i and [caffeine]i . J. Physiol. , 425 : 55 – 70 . [PUBMED] [INFOTRIEVE] [CSA]
- Rasmussen , H. and Barrett , P. Q. 1984 . Calcium messenger system: An integrated view . Physiol. Rev. , 64 : 938 – 984 . [PUBMED] [INFOTRIEVE] [CSA]
- Winder , W. W. 1986 . Effect of intravenous caffeine on liver glycogenolysis during prolonged exercise . Med. Sci. Sports Exerc. , 18 : 192 – 196 . [PUBMED] [INFOTRIEVE] [CSA]
- Niewoehner , C. B. and Nuttall , F. Q. 1988 . Relationship of hepatic glucose uptake to intrahepatic glucose concentration in fasted rats after glucose load . Diabetes , 37 : 1559 – 1566 . [PUBMED] [INFOTRIEVE] [CSA]
- Arogyasami , J. , Yang , H. T. and Winder , W. W. 1989 . Effect of intravenous caffeine on muscle glycogenolysis in fasted exercising rats . Med. Sci. Sports Exerc. , 21 : 167 – 172 . [PUBMED] [INFOTRIEVE] [CSA]
- Arogyasami , J. , Yang , H. T. and Winder , W. W. 1989 . Effect of caffeine on glycogenolysis during exercise in endurance trained rats . Med. Sci. Sports Exerc. , 21 : 173 – 177 . [PUBMED] [INFOTRIEVE] [CSA]