Synthesis of Novel Acyclic Nucleoside Analogue Starting From 6-Aminouracil as Potent Antimicrobial Agent

References

• L. Liang, M. S. Xie, T. Qin, M. Zhu, G. R. Qu, and H. M. Guo, “Regio- and Enantioselective Synthesis of Chiral Pyrimidine Acyclic Nucleosides via Rhodium-Catalyzed Asymmetric Allylation of Pyrimidines,” Organic Letters 19, no. 19 (2017): 5212–15.
   PubMed Web of Science ®Google Scholar
• A. Holý, “Antiviral Acyclic Nucleoside Phosphonates Structure Activity Studies,” Antiviral Research 71, no. 2–3 (2006): 248–53.
   PubMed Web of Science ®Google Scholar
• D. Hocková, D. T. Keough, Z. Janeba, T. H. Wang, J. De Jersey, and L. W. Guddat, “Synthesis of Novel N-Branched Acyclic Nucleoside Phosphonates as Potent and Selective Inhibitors of Human, Plasmodium Falciparum and Plasmodium Vivax 6-Oxopurine Phosphoribosyltransferases,” Journal of Medicinal Chemistry 55, no. 13 (2012): 6209–23.
   PubMed Web of Science ®Google Scholar
• Kun-Peng Shao, Xu-Yao Zhang, Peng-Ju Chen, Deng-Qi Xue, Peng He, Li-Ying Ma, Jia-Xin Zheng, Qiu-Rong Zhang, and Hong-Min Liu, “Synthesis and Biological Evaluation of Novel Pyrimidine-Benzimidazol Hybrids as Potential Anticancer Agents,” Bioorganic & Medicinal Chemistry Letters 24, no. 16 (2014): 3877–81.
   PubMed Web of Science ®Google Scholar
• V. Sharma, N. Chitranshi, and A. K. Agarwal, “Significance and Biological Importance of Pyrimidine in The Microbial World,” International Journal of Medicinal Chemistry 2014 (2014): 202784.
   PubMedGoogle Scholar
• H. H. Sayed, A. H. Shampoukh, and Y. E. Rashad, “Synthesis and Biological Evaluation of Some Pyrimidine, Pyrimido[2,1-b][1,3]Thiazine and Thiazolo[3,2-a]Pyrimidine Derivatives,” Acta Pharmaceutica 56 (2006): 231–44.
   PubMedGoogle Scholar
• Z. Seferoǧlu and N. Ertan, “Synthesis, Characterization and Spectroscopic Properties of Some New Phenylazo-6-Aminouracil,” Central European Journal of Chemistry 6, no. 1 (2008): 81–88.
   Google Scholar
• A. Shahrzad, “ZnO Nanoparticles-Catalyzed Cyclocondensation Reaction of Arylmethylidenepyruvic Acids with 6-Aminouracils,” Combinatorial Chemistry & High Throughput Screening 16, no. 1 (2013): 32–36.
   PubMed Web of Science ®Google Scholar
• F. B. Essa, A. Bazbouz, and S. Al-lababidi, “Preparation, Chemical and Biological Study of Acyclovir Analogue Starting from 6-Aminouracil,” Oriental Journal of Chemistry 26, no. 4 (2010): 1281–92.
   Google Scholar
• G. Abu Sheikha, P. La Colla, and A. G. Loi, “A New Class of Acyclic Nucleoside Phosphonates: Synthesis and Biological Activity of 9-{[(Phosphonomethyl) Aziridin-1-yl]Methyl}Guanine (PMAMG) and Analogues,” Nucleosides, Nucleotides, and Nucleic Acids 21, no. 10 (2002): 619–35.
   PubMed Web of Science ®Google Scholar
• M. Koszytkowska-Stawińska, K. Kaleta, W. Sas, and E. De Clercq, “Synthesis and Antiviral Properties of Aza-Analogues of Acyclovir,” Nucleosides, Nucleotides, and Nucleic Acids 26 (2007): 51–64.
   PubMed Web of Science ®Google Scholar
• F. B. Essa, A. Bazbouz, S. Alhilal, S. M. Gomha, and S. A. Ouf, “Synthesis and Biological Evaluation of an Indole Core-4 Based Derivative with Potent Antimicrobial Activity,” Research on Chemical Intermediates. 44 (2018): 5345–56.
   Web of Science ®Google Scholar
• H. Gao and A. K. Mitra, “Synthesis of Acyclovir, Ganciclovir and Their Prodrugs: A Review,” Synthesis 3 (2000): 329–51.
   Google Scholar
• W. R. Sherman and E. C. Taylor, Jr.; Checked by T. L. Cairns and D. S. Acker, “Diaminouracil Hydrochloride [Uracil, 5,6-Diamino-, Hydrochloride],” Organic Synthesis 4 (1963): 247; 37 (1957): 15.
   Google Scholar
• S. Marincean, M. R. Smith, L. Beltz, and B. Borhan, “Selectivity of Labeled Bromoethylamine for Protein Alkylation,” Journal of Molecular Modeling 18 (2012): 4547–56.
   PubMed Web of Science ®Google Scholar
• A. Alahiane, A. Rochdi, M. Taourirte, N. Redwane, S. Sebti, and H. B. Lazrek, “Natural Phosphate as Lewis Acid Catalyst: A Simple and Convenient Method for Acyclonucleoside Synthesis,” Tetrahedron Letters 42, no. 21 (2001): 3579–81.
   Web of Science ®Google Scholar
• G. M. Friedrichsen, W. Chen, M. Begtrup, C. P. Lee, P. L. Smith, and R. T. Borchardt, “Synthesis of Analogs of L-Valacyclovir and Determination of Their Substrate Activity for the Oligopeptide Transporter in Caco-2 Cells,”. European Journal of Pharmaceutical Sciences 16 (2002): 1–13.
   PubMed Web of Science ®Google Scholar
• G.-F. Huang and M. Okada, “Synthesis and Antiviral Activity of 5-[(Cyanomethylene) Oxy]-2′-Deoxyuridine,” Journal of Medicinal Chemistry. 24 (1981): 390–93.
   PubMed Web of Science ®Google Scholar
• X. Zhou and X. Chen, “An Easy-to-Operate n-Carbonylation of Indoles with Diaryl Carbonates as Reagent and Na2CO3 as Catalyst,” Synthetic Communications 50, no. 12 (2020): 1–9.
   Web of Science ®Google Scholar
• D. S. Pedersen, T. Boesen, A. B. Eldrup, B. Kiaer, C. Madsen, U. Henriksen, and O. Dahl. “The First Example of a New Type of Acyclic, Achiral Nucleoside Analogue: 1-[3-Hydroxy-2-(Hydroxymethyl)Prop-1-Enyl]Thymine,” Journal of the Chemical Society, Perkin Transactions 1 14 (2001): 1656–61.
   Google Scholar
• R. M. Shaker, M. Abd Elrady, and K. U. Sadek, “Synthesis, Reactivity, and Biological Activity of 5-Aminouracil and Its Derivatives,” Molecular Diversity 20 (2016): 153–83.
   PubMed Web of Science ®Google Scholar
• M. Nakazono, A. Uesaki, and K. Zaitsu, “The Chemiluminescence Mechanism of 3,4-Bis(3-Indolyl)-1H-Pyrrole-2,5-Dione, and the Characteristics of Chemiluminescence Developed in the Reaction with CH3CNH2O2NaOH,” Talanta 70, no. 1 (2006): 128–32.
   PubMed Web of Science ®Google Scholar
• H. Gao and A. K. Mitra, “Regioselective Synthesis of Various Prodrugs of Ganciclovir,” Tetrahedron Letters 41 (2000): 1131–36.
   Web of Science ®Google Scholar
• P. Bravo, G. Resnati, and F. Vianib, “Optically Pure and Fluoro Substituted Acyclovir Analogues,” Tetrahedron 49, no. 3 (1993): 713–20.
   Web of Science ®Google Scholar
• N. Rosas, P. Sharma, C. Alvarez, A. Cabrera, R. Ramirez, A. Delgado, and H. Arzoumanian, “Novel and Facile Catalytic Synthesis of 2,4-Dioxopyrido[2,3-d]-Pyrimidine Derivatives in Water,” Journal of the Chemical Society, Perkin Transactions 1 19 (2001): 2341–43.
   Google Scholar
• G. Paragi, E. Szájli, F. Bogár, L. Kovács, C. F. Guerra, and F. M. Bickelhaupt, “Hydrogen Bonding of 3- and 5-Methyl-6-Aminouracil with Natural DNA bases,” New Journal of Chemistry 32, no. 11 (2008): 1981–87.
   Web of Science ®Google Scholar
• S. A. Ouf and S. M. Sherif, “Synthesis and Fungitoxicity of Some Pyrimidine Derivatives,” Folia Microbiologica 38, no. 3 (1993): 181–87.
   PubMed Web of Science ®Google Scholar
• S. A. Ouf, S. M. Gomha, M. M. Ewies, and I. A. A. Sharawy, “Synthesis, Characterization, and Antifungal Activity Evaluation of Some Novel Arylazothiazoles,” Journal of Heterocyclic Chemistry 55, no. 1 (2018): 258–64.
   Web of Science ®Google Scholar
• A. S. Abd Elmegeed, S. A. Ouf, T. A. Moussaa, and S. M. R. Eltahlawid, “Dermatophytes and Other Associated Fungi in Patients Attending to Some Hospitals in Egypt,” Brazilian Journal of Microbiology 46 (2015): 799–805.
   PubMed Web of Science ®Google Scholar
• Salama A. Ouf, Tarek A. Moussa, Alshimaa M. Abd-Elmegeed, and Samar R. Eltahlawy, “Anti-Fungal Potential of Ozone Against Some Dermatophytes,” Brazilian Journal of Microbiology 47, no. 3 (2016): 697–702.
   PubMed Web of Science ®Google Scholar
• M. Alhilal, Y. A. M. Sulaiman, S. Alhilal, S. M. Gomha, and S. A. Ouf, “Anti-Fungal Activity of New Diterpenoid Akaloids Isolated by Different Chromatographic Methods from Delphinium peregrinum L. Var. Eriocarpum boiss,” Molecules 26 (2021): 1375.
   PubMed Web of Science ®Google Scholar